STRINGSTRING
A9D14_00165 A9D14_00165 A9D14_00960 A9D14_00960 pckA pckA A9D14_02105 A9D14_02105 A9D14_02110 A9D14_02110 A9D14_02445 A9D14_02445 A9D14_02795 A9D14_02795 A9D14_03120 A9D14_03120 A9D14_03125 A9D14_03125 glcB glcB acsA acsA A9D14_03330 A9D14_03330 A9D14_04210 A9D14_04210 mdh mdh accD accD gloB gloB leuA leuA A9D14_06410 A9D14_06410 fumC fumC A9D14_07110 A9D14_07110 A9D14_07630 A9D14_07630 A9D14_07640 A9D14_07640 A9D14_07905 A9D14_07905 pdhA pdhA A9D14_09380 A9D14_09380 A9D14_09420 A9D14_09420 accA accA A9D14_09850 A9D14_09850 A9D14_10100 A9D14_10100 A9D14_12560 A9D14_12560 A9D14_13415 A9D14_13415 A9D14_14490 A9D14_14490 A9D14_15035 A9D14_15035 A9D14_15190 A9D14_15190 A9D14_16030 A9D14_16030 A9D14_16180 A9D14_16180 A9D14_16220 A9D14_16220 A9D14_16275 A9D14_16275 A9D14_16600 A9D14_16600 A9D14_17080 A9D14_17080 A9D14_18025 A9D14_18025 A9D14_18055 A9D14_18055 A9D14_19245 A9D14_19245 A9D14_19250 A9D14_19250
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
A9D14_00165Unannotated protein; Belongs to the pyruvate kinase family. (489 aa)
A9D14_00960Unannotated protein; Catalyzes the conversion of acetaldehyde to acetyl-CoA, using NAD(+) and coenzyme A. Is the final enzyme in the meta-cleavage pathway for the degradation of aromatic compounds. (313 aa)
pckAUnannotated protein; Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA. (529 aa)
A9D14_02105Unannotated protein. (646 aa)
A9D14_02110Unannotated protein. (353 aa)
A9D14_02445Unannotated protein. (145 aa)
A9D14_02795Unannotated protein; Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle. (929 aa)
A9D14_03120Unannotated protein; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. (449 aa)
A9D14_03125Unannotated protein; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. (169 aa)
glcBUnannotated protein; Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl- CoA) and glyoxylate to form malate and CoA; Belongs to the malate synthase family. GlcB subfamily. (714 aa)
acsAUnannotated protein; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family. (655 aa)
A9D14_03330Unannotated protein; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (339 aa)
A9D14_04210Unannotated protein. (467 aa)
mdhUnannotated protein; Catalyzes the reversible oxidation of malate to oxaloacetate. Belongs to the LDH/MDH superfamily. MDH type 3 family. (320 aa)
accDUnannotated protein; Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA; Belongs to the AccD/PCCB family. (283 aa)
gloBUnannotated protein; Thiolesterase that catalyzes the hydrolysis of S-D-lactoyl- glutathione to form glutathione and D-lactic acid. (252 aa)
leuAUnannotated protein; Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3- hydroxy-4-methylpentanoate (2-isopropylmalate); Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 2 subfamily. (560 aa)
A9D14_06410Unannotated protein; Belongs to the PEP-utilizing enzyme family. (888 aa)
fumCUnannotated protein; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily. (462 aa)
A9D14_07110Unannotated protein; Belongs to the TPP enzyme family. (594 aa)
A9D14_07630Unannotated protein. (470 aa)
A9D14_07640Unannotated protein; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). (441 aa)
A9D14_07905Unannotated protein; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2. (462 aa)
pdhAUnannotated protein; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). (352 aa)
A9D14_09380Unannotated protein. (127 aa)
A9D14_09420Unannotated protein. (228 aa)
accAUnannotated protein; Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA. (318 aa)
A9D14_09850Unannotated protein. (88 aa)
A9D14_10100Unannotated protein; Belongs to the thiolase-like superfamily. Thiolase family. (393 aa)
A9D14_12560Unannotated protein. (757 aa)
A9D14_13415Unannotated protein; Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family. (508 aa)
A9D14_14490Unannotated protein; Belongs to the aldehyde dehydrogenase family. (493 aa)
A9D14_15035Unannotated protein; Belongs to the thiolase-like superfamily. Thiolase family. (401 aa)
A9D14_15190Unannotated protein. (232 aa)
A9D14_16030Unannotated protein. (712 aa)
A9D14_16180Unannotated protein; Belongs to the thiolase-like superfamily. Thiolase family. (405 aa)
A9D14_16220Unannotated protein; Belongs to the thiolase-like superfamily. Thiolase family. (392 aa)
A9D14_16275Unannotated protein; Belongs to the thiolase-like superfamily. Thiolase family. (393 aa)
A9D14_16600Unannotated protein. (478 aa)
A9D14_17080Unannotated protein; Belongs to the thiolase-like superfamily. Thiolase family. (420 aa)
A9D14_18025Unannotated protein; Belongs to the TPP enzyme family. (594 aa)
A9D14_18055Unannotated protein. (450 aa)
A9D14_19245Unannotated protein; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (335 aa)
A9D14_19250Unannotated protein; Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate; Belongs to the PEP-utilizing enzyme family. (807 aa)
Your Current Organism:
Croceicoccus marinus
NCBI taxonomy Id: 450378
Other names: CGMCC 1.6776, Croceicoccus marinus Xu et al. 2009 emend. Huang et al. 2015, JCM 14846, Sphingomonadaceae bacterium E4A9, strain E4A9
Server load: low (18%) [HD]