STRINGSTRING
A9D14_00025 A9D14_00025 A9D14_00070 A9D14_00070 argD argD A9D14_01005 A9D14_01005 A9D14_01010 A9D14_01010 ilvD ilvD argB argB argJ argJ leuD leuD leuC leuC leuB leuB A9D14_04400 A9D14_04400 A9D14_05400 A9D14_05400 A9D14_05665 A9D14_05665 A9D14_05840 A9D14_05840 leuA leuA ilvC ilvC A9D14_06065 A9D14_06065 A9D14_06070 A9D14_06070 asd asd argC argC A9D14_12010 A9D14_12010 A9D14_18945 A9D14_18945
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
A9D14_00025Unannotated protein; Belongs to the aspartokinase family. (422 aa)
A9D14_00070Unannotated protein; Catalyzes the isomerization of citrate to isocitrate via cis- aconitate. (893 aa)
argDUnannotated protein; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily. (396 aa)
A9D14_01005Unannotated protein. (365 aa)
A9D14_01010Unannotated protein. (646 aa)
ilvDUnannotated protein; Belongs to the IlvD/Edd family. (618 aa)
argBUnannotated protein; Catalyzes the ATP-dependent phosphorylation of N-acetyl-L- glutamate; Belongs to the acetylglutamate kinase family. ArgB subfamily. (302 aa)
argJUnannotated protein; Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis: the synthesis of N-acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate. Belongs to the ArgJ family. (406 aa)
leuDUnannotated protein; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. Belongs to the LeuD family. LeuD type 1 subfamily. (200 aa)
leuCUnannotated protein; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. (483 aa)
leuBUnannotated protein; Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate. (351 aa)
A9D14_04400Unannotated protein; Belongs to the isocitrate and isopropylmalate dehydrogenases family. (408 aa)
A9D14_05400Unannotated protein; Belongs to the citrate synthase family. (427 aa)
A9D14_05665Unannotated protein. (367 aa)
A9D14_05840Unannotated protein; Belongs to the IlvD/Edd family. (598 aa)
leuAUnannotated protein; Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3- hydroxy-4-methylpentanoate (2-isopropylmalate); Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 2 subfamily. (560 aa)
ilvCUnannotated protein; Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate. (339 aa)
A9D14_06065Unannotated protein. (171 aa)
A9D14_06070Unannotated protein. (586 aa)
asdUnannotated protein; Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl- 4-phosphate; Belongs to the aspartate-semialdehyde dehydrogenase family. (341 aa)
argCUnannotated protein; Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde. Belongs to the NAGSA dehydrogenase family. Type 2 subfamily. (314 aa)
A9D14_12010Unannotated protein. (403 aa)
A9D14_18945Unannotated protein; Belongs to the TPP enzyme family. (546 aa)
Your Current Organism:
Croceicoccus marinus
NCBI taxonomy Id: 450378
Other names: CGMCC 1.6776, Croceicoccus marinus Xu et al. 2009 emend. Huang et al. 2015, JCM 14846, Sphingomonadaceae bacterium E4A9, strain E4A9
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