STRINGSTRING
Aasi_0016 Aasi_0016 Aasi_0029 Aasi_0029 Aasi_0058 Aasi_0058 Aasi_0077 Aasi_0077 Aasi_0091 Aasi_0091 Aasi_0105 Aasi_0105 Aasi_0114 Aasi_0114 Aasi_0119 Aasi_0119 Aasi_0130 Aasi_0130 eno eno Aasi_0166 Aasi_0166 Aasi_0199 Aasi_0199 Aasi_0227 Aasi_0227 adk adk glyA glyA Aasi_0283 Aasi_0283 gpsA gpsA gpmI gpmI Aasi_0304 Aasi_0304 accA accA Aasi_0352 Aasi_0352 Aasi_0369 Aasi_0369 fbp fbp Aasi_0423 Aasi_0423 asd asd Aasi_0435 Aasi_0435 Aasi_0474 Aasi_0474 gltX gltX Aasi_0566 Aasi_0566 Aasi_0651 Aasi_0651 miaA miaA Aasi_0715 Aasi_0715 Aasi_0716 Aasi_0716 pgk pgk Aasi_0775 Aasi_0775 Aasi_0781 Aasi_0781 psd psd dapF dapF Aasi_0901 Aasi_0901 Aasi_0946 Aasi_0946 pckA pckA Aasi_1062 Aasi_1062 Aasi_1063 Aasi_1063 Aasi_1064 Aasi_1064 Aasi_1065 Aasi_1065 Aasi_1069 Aasi_1069 Aasi_1205 Aasi_1205 acpP acpP Aasi_1209 Aasi_1209 dapA dapA Aasi_1420 Aasi_1420 Aasi_1427 Aasi_1427 Aasi_1430 Aasi_1430 accD accD tpiA tpiA Aasi_1558 Aasi_1558 pdhA pdhA Aasi_1786 Aasi_1786
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
Your Input:
Aasi_0016Phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain I; PRINTS: PR00419, Adrenodoxin reductase;PR00469, Pyridine nucleotide-disulphide oxidoreductase, class-II;PR00368, FAD-dependent pyridine nucleotide-disulphide oxidoreductase; PROSITE: PS00573, Pyridine nucleotide-disulphide oxidoreductase, class-II, active site; PFAM: PF00070, Pyridine nucleotide-disulphide oxidoreductase, NAD-binding region;PF07992, FAD-dependent pyridine nucleotide-disulphide oxidoreductase; PRODOM: PD000139, Pyridine nucleotide-disulphide oxidoreductase, NAD-binding region; TIGRFAMS: TIGR01292, Thioredo [...] (464 aa)
Aasi_0029Catalytic domain of components of various dehydrogenase complexes; PFAM: PF07676, WD40-like Beta Propeller; GENE3D: G3DSA:2.120.10.30, Six-bladed beta-propeller, TolB-like. (414 aa)
Aasi_0058Enoyl-(acyl-carrier-protein) reductase (NADH); PFAM: PF01618, MotA/TolQ/ExbB proton channel. (268 aa)
Aasi_0077Nucleotidyl transferase; PFAM: PF00892, Protein of unknown function DUF6, transmembrane. (336 aa)
Aasi_0091CDP-diacylglycerol/serine O-phosphatidyltransferase; Belongs to the CDP-alcohol phosphatidyltransferase class-I family. (233 aa)
Aasi_01053-oxoacyl-(acyl-carrier-protein) reductase; Catalyzes the NADPH-dependent reduction of beta-ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products, the first reductive step in the elongation cycle of fatty acid biosynthesis. Belongs to the short-chain dehydrogenases/reductases (SDR) family. (248 aa)
Aasi_0114Thiamine pyrophosphate protein domain protein TPP-binding; PANTHER: PTHR12919, Ribosomal protein S16; PFAM: PF00886, Ribosomal protein S16; SUPERFAMILY: SSF54565, Ribosomal protein S16; PRODOM: PD003791, Ribosomal protein S16; GENE3D: G3DSA:3.30.1320.10, Ribosomal protein S16; TIGRFAMS: TIGR00002, Ribosomal protein S16; Belongs to the TPP enzyme family. (589 aa)
Aasi_0119Nucleotidyl transferase; PFAM: PF02776, Thiamine pyrophosphate enzyme, N-terminal TPP binding region;PF00205, Thiamine pyrophosphate enzyme, central region;PF02775, Thiamine pyrophosphate enzyme, C-terminal TPP-binding. (362 aa)
Aasi_0130Phospholipase D/Transphosphatidylase; PRINTS: PR00971, Ribosomal protein S10; PANTHER: PTHR11700:SF2, Ribosomal protein S10, bacterial;PTHR11700, Ribosomal protein S10; PFAM: PF00338, Ribosomal protein S10; SUPERFAMILY: SSF54999, Ribosomal protein S10; PRODOM: PD001272, Ribosomal protein S10; GENE3D: G3DSA:3.30.70.600, Ribosomal protein S10; TIGRFAMS: TIGR01049, Ribosomal protein S10, bacterial. (198 aa)
enoEnolase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family. (427 aa)
Aasi_0166Starch synthase catalytic domain protein. (270 aa)
Aasi_0199PROSITE: PS00467, Ribosomal protein L2; PANTHER: PTHR13691:SF5, Ribosomal protein L2, bacterial-type;PTHR13691, Ribosomal protein L2; PFAM: PF03947, Ribosomal protein L2;PF00181, Ribosomal protein L2; SUPERFAMILY: SSF50249, Nucleic acid-binding, OB-fold-like;SSF50104, Translation protein SH3-like; PIR: PIRSF002158, Ribosomal protein L2; GENE3D: G3DSA:2.40.50.140, Nucleic acid-binding, OB-fold;G3DSA:2.30.30.30, Translation protein SH3-like, subgroup; TIGRFAMS: TIGR01171, Ribosomal protein L2, bacterial-type. (293 aa)
Aasi_0227Hypothetical protein. (203 aa)
adkHypothetical protein; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family. (193 aa)
glyAHypothetical protein; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. (422 aa)
Aasi_0283Hypothetical protein; PROFILE: PS51192, Helicase, superfamily 1 and 2, ATP-binding;PS51194, DNA/RNA helicase, C-terminal; PFAM: PF02559, Transcription factor CarD;PF00270, DNA/RNA helicase, DEAD/DEAH box type, N-terminal;PF03461, TRCF;PF00271, DNA/RNA helicase, C-terminal; SMART: SM00487, DEAD-like helicase, N-terminal;SM00490, DNA/RNA helicase, C-terminal; TIGRFAMS: TIGR00580, Transcription-repair coupling factor. (551 aa)
gpsAHypothetical protein; Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family. (354 aa)
gpmIHypothetical protein; Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate. (507 aa)
Aasi_0304Hypothetical protein; PRINTS: PR00502, NUDIX hydrolase, core; PFAM: PF00293, NUDIX hydrolase, core; SUPERFAMILY: SSF55811, NUDIX; GENE3D: G3DSA:3.90.79.10, NUDIX hydrolase, core; Belongs to the DapB family. (240 aa)
accAHypothetical protein; Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA. (316 aa)
Aasi_0352Hypothetical protein; Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine. Belongs to the anaerobic coproporphyrinogen-III oxidase family. (375 aa)
Aasi_0369Hypothetical protein; Belongs to the aspartokinase family. (427 aa)
fbpHypothetical protein; PFAM: PF01351, Ribonuclease HII/HIII; SUPERFAMILY: SSF53098, Polynucleotidyl transferase, Ribonuclease H fold. (331 aa)
Aasi_0423Hypothetical protein; Belongs to the Glu/Leu/Phe/Val dehydrogenases family. (368 aa)
asdHypothetical protein; Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl- 4-phosphate; Belongs to the aspartate-semialdehyde dehydrogenase family. (332 aa)
Aasi_0435Hypothetical protein. (478 aa)
Aasi_0474Hypothetical protein; PFAM: PF03400, Transposase, IS1; Belongs to the NDK family. (130 aa)
gltXHypothetical protein; Catalyzes the attachment of glutamate to tRNA(Glu) in a two- step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu); Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily. (512 aa)
Aasi_0566Hypothetical protein. (215 aa)
Aasi_0651Hypothetical protein; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2. (325 aa)
miaAHypothetical protein; Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A); Belongs to the IPP transferase family. (313 aa)
Aasi_0715Hypothetical protein; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. (162 aa)
Aasi_0716Hypothetical protein; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. (454 aa)
pgkHypothetical protein; Belongs to the phosphoglycerate kinase family. (401 aa)
Aasi_0775Hypothetical protein; PROFILE: PS50293, Tetratricopeptide region;PS50005, Tetratricopeptide region; PFAM: PF08238, Sel1-like;PF00515, Tetratricopeptide TPR-1; GENE3D: G3DSA:1.25.40.10, Tetratricopeptide-like helical; SMART: SM00671, Sel1-like;SM00028, Tetratricopeptide region; Belongs to the FPP/GGPP synthase family. (324 aa)
Aasi_0781Hypothetical protein; Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids. (288 aa)
psdHypothetical protein; Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer). (225 aa)
dapFHypothetical protein; Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L- lysine and an essential component of the bacterial peptidoglycan. (258 aa)
Aasi_0901Hypothetical protein; PANTHER: PTHR10954, Ribonuclease HII/HIII; PFAM: PF01351, Ribonuclease HII/HIII; SUPERFAMILY: SSF53098, Polynucleotidyl transferase, Ribonuclease H fold. (603 aa)
Aasi_0946Hypothetical protein. (139 aa)
pckAHypothetical protein; Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA. (520 aa)
Aasi_1062Hypothetical protein; Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4-hexulose. Belongs to the dTDP-4-dehydrorhamnose 3,5-epimerase family. (186 aa)
Aasi_1063Hypothetical protein; Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4-hexulose to yield dTDP-L-rhamnose. (290 aa)
Aasi_1064Hypothetical protein; PRINTS: PR01415, Ankyrin; PROFILE: PS50297, Ankyrin;PS50088, Ankyrin; PFAM: PF00023, Ankyrin; SUPERFAMILY: SSF48403, Ankyrin; GENE3D: G3DSA:1.25.40.20, Ankyrin; SMART: SM00248, Ankyrin; Belongs to the NAD(P)-dependent epimerase/dehydratase family. dTDP-glucose dehydratase subfamily. (337 aa)
Aasi_1065Hypothetical protein; PFAM: PF02657, Fe-S metabolism associated SufE. (328 aa)
Aasi_1069Hypothetical protein; PFAM: PF01609, Transposase, IS4-like; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family. (331 aa)
Aasi_1205Hypothetical protein. (182 aa)
acpPHypothetical protein; Carrier of the growing fatty acid chain in fatty acid biosynthesis; Belongs to the acyl carrier protein (ACP) family. (80 aa)
Aasi_1209Hypothetical protein; Belongs to the pyruvate kinase family. (481 aa)
dapAHypothetical protein; Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA). (295 aa)
Aasi_1420PRINTS: PR01021, Outer membrane protein, bacterial; PROFILE: PS50293, Tetratricopeptide region;PS50005, Tetratricopeptide region;PS51123, Outer membrane protein, OmpA/MotB, C-terminal; PFAM: PF00691, Outer membrane protein, OmpA/MotB, C-terminal;PF07719, Tetratricopeptide TPR2;PF07676, WD40-like Beta Propeller; SUPERFAMILY: SSF103088, Outer membrane protein, OmpA/MotB, C-terminal; PRODOM: PD000930, Outer membrane protein, OmpA/MotB, C-terminal; GENE3D: G3DSA:1.25.40.10, Tetratricopeptide-like helical;G3DSA:2.120.10.30, Six-bladed beta-propeller, TolB-like;G3DSA:3.30.1330.60, Outer memb [...] (461 aa)
Aasi_1427Hypothetical protein. (402 aa)
Aasi_1430PFAM: PF03811, Insertion element protein; SUPERFAMILY: SSF46689, Homeodomain-like. (352 aa)
accDHypothetical protein; Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA. (281 aa)
tpiAHypothetical protein; Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P); Belongs to the triosephosphate isomerase family. (267 aa)
Aasi_1558Hypothetical protein. (303 aa)
pdhAHypothetical protein; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). (345 aa)
Aasi_1786Hypothetical protein. (277 aa)
Your Current Organism:
Amoebophilus asiaticus
NCBI taxonomy Id: 452471
Other names: C. Amoebophilus asiaticus 5a2, Candidatus Amoebophilus asiaticus 5a2, Candidatus Amoebophilus asiaticus str. 5a2, Candidatus Amoebophilus asiaticus strain 5a2
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