| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| Pnec_0337 | Pnec_0810 | Pnec_0337 | Pnec_0810 | PFAM: thiamine pyrophosphate protein domain protein TPP-binding; thiamine pyrophosphate protein central region; thiamine pyrophosphate protein TPP binding domain protein; KEGG: rpa:RPA4054 possible acetolactate synthase large subunit; Belongs to the TPP enzyme family. | TIGRFAM: acetolactate synthase, large subunit, biosynthetic type; PFAM: thiamine pyrophosphate protein domain protein TPP-binding; thiamine pyrophosphate protein central region; thiamine pyrophosphate protein TPP binding domain protein; KEGG: pnu:Pnuc_1063 acetolactate synthase, large subunit, biosynthetic type. | 0.926 |
| Pnec_0337 | Pnec_0811 | Pnec_0337 | Pnec_0811 | PFAM: thiamine pyrophosphate protein domain protein TPP-binding; thiamine pyrophosphate protein central region; thiamine pyrophosphate protein TPP binding domain protein; KEGG: rpa:RPA4054 possible acetolactate synthase large subunit; Belongs to the TPP enzyme family. | TIGRFAM: acetolactate synthase, small subunit; PFAM: amino acid-binding ACT domain protein; KEGG: pnu:Pnuc_1062 acetolactate synthase 3 regulatory subunit. | 0.997 |
| Pnec_0337 | Pnec_0838 | Pnec_0337 | Pnec_0838 | PFAM: thiamine pyrophosphate protein domain protein TPP-binding; thiamine pyrophosphate protein central region; thiamine pyrophosphate protein TPP binding domain protein; KEGG: rpa:RPA4054 possible acetolactate synthase large subunit; Belongs to the TPP enzyme family. | KEGG: pnu:Pnuc_1028 tartrate dehydrogenase. | 0.927 |
| Pnec_0337 | ilvC | Pnec_0337 | Pnec_0812 | PFAM: thiamine pyrophosphate protein domain protein TPP-binding; thiamine pyrophosphate protein central region; thiamine pyrophosphate protein TPP binding domain protein; KEGG: rpa:RPA4054 possible acetolactate synthase large subunit; Belongs to the TPP enzyme family. | Ketol-acid reductoisomerase; Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate. | 0.984 |
| Pnec_0810 | Pnec_0337 | Pnec_0810 | Pnec_0337 | TIGRFAM: acetolactate synthase, large subunit, biosynthetic type; PFAM: thiamine pyrophosphate protein domain protein TPP-binding; thiamine pyrophosphate protein central region; thiamine pyrophosphate protein TPP binding domain protein; KEGG: pnu:Pnuc_1063 acetolactate synthase, large subunit, biosynthetic type. | PFAM: thiamine pyrophosphate protein domain protein TPP-binding; thiamine pyrophosphate protein central region; thiamine pyrophosphate protein TPP binding domain protein; KEGG: rpa:RPA4054 possible acetolactate synthase large subunit; Belongs to the TPP enzyme family. | 0.926 |
| Pnec_0810 | Pnec_0811 | Pnec_0810 | Pnec_0811 | TIGRFAM: acetolactate synthase, large subunit, biosynthetic type; PFAM: thiamine pyrophosphate protein domain protein TPP-binding; thiamine pyrophosphate protein central region; thiamine pyrophosphate protein TPP binding domain protein; KEGG: pnu:Pnuc_1063 acetolactate synthase, large subunit, biosynthetic type. | TIGRFAM: acetolactate synthase, small subunit; PFAM: amino acid-binding ACT domain protein; KEGG: pnu:Pnuc_1062 acetolactate synthase 3 regulatory subunit. | 0.999 |
| Pnec_0810 | Pnec_0838 | Pnec_0810 | Pnec_0838 | TIGRFAM: acetolactate synthase, large subunit, biosynthetic type; PFAM: thiamine pyrophosphate protein domain protein TPP-binding; thiamine pyrophosphate protein central region; thiamine pyrophosphate protein TPP binding domain protein; KEGG: pnu:Pnuc_1063 acetolactate synthase, large subunit, biosynthetic type. | KEGG: pnu:Pnuc_1028 tartrate dehydrogenase. | 0.927 |
| Pnec_0810 | ilvC | Pnec_0810 | Pnec_0812 | TIGRFAM: acetolactate synthase, large subunit, biosynthetic type; PFAM: thiamine pyrophosphate protein domain protein TPP-binding; thiamine pyrophosphate protein central region; thiamine pyrophosphate protein TPP binding domain protein; KEGG: pnu:Pnuc_1063 acetolactate synthase, large subunit, biosynthetic type. | Ketol-acid reductoisomerase; Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate. | 0.995 |
| Pnec_0811 | Pnec_0337 | Pnec_0811 | Pnec_0337 | TIGRFAM: acetolactate synthase, small subunit; PFAM: amino acid-binding ACT domain protein; KEGG: pnu:Pnuc_1062 acetolactate synthase 3 regulatory subunit. | PFAM: thiamine pyrophosphate protein domain protein TPP-binding; thiamine pyrophosphate protein central region; thiamine pyrophosphate protein TPP binding domain protein; KEGG: rpa:RPA4054 possible acetolactate synthase large subunit; Belongs to the TPP enzyme family. | 0.997 |
| Pnec_0811 | Pnec_0810 | Pnec_0811 | Pnec_0810 | TIGRFAM: acetolactate synthase, small subunit; PFAM: amino acid-binding ACT domain protein; KEGG: pnu:Pnuc_1062 acetolactate synthase 3 regulatory subunit. | TIGRFAM: acetolactate synthase, large subunit, biosynthetic type; PFAM: thiamine pyrophosphate protein domain protein TPP-binding; thiamine pyrophosphate protein central region; thiamine pyrophosphate protein TPP binding domain protein; KEGG: pnu:Pnuc_1063 acetolactate synthase, large subunit, biosynthetic type. | 0.999 |
| Pnec_0811 | Pnec_0838 | Pnec_0811 | Pnec_0838 | TIGRFAM: acetolactate synthase, small subunit; PFAM: amino acid-binding ACT domain protein; KEGG: pnu:Pnuc_1062 acetolactate synthase 3 regulatory subunit. | KEGG: pnu:Pnuc_1028 tartrate dehydrogenase. | 0.966 |
| Pnec_0811 | ilvC | Pnec_0811 | Pnec_0812 | TIGRFAM: acetolactate synthase, small subunit; PFAM: amino acid-binding ACT domain protein; KEGG: pnu:Pnuc_1062 acetolactate synthase 3 regulatory subunit. | Ketol-acid reductoisomerase; Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate. | 0.998 |
| Pnec_0838 | Pnec_0337 | Pnec_0838 | Pnec_0337 | KEGG: pnu:Pnuc_1028 tartrate dehydrogenase. | PFAM: thiamine pyrophosphate protein domain protein TPP-binding; thiamine pyrophosphate protein central region; thiamine pyrophosphate protein TPP binding domain protein; KEGG: rpa:RPA4054 possible acetolactate synthase large subunit; Belongs to the TPP enzyme family. | 0.927 |
| Pnec_0838 | Pnec_0810 | Pnec_0838 | Pnec_0810 | KEGG: pnu:Pnuc_1028 tartrate dehydrogenase. | TIGRFAM: acetolactate synthase, large subunit, biosynthetic type; PFAM: thiamine pyrophosphate protein domain protein TPP-binding; thiamine pyrophosphate protein central region; thiamine pyrophosphate protein TPP binding domain protein; KEGG: pnu:Pnuc_1063 acetolactate synthase, large subunit, biosynthetic type. | 0.927 |
| Pnec_0838 | Pnec_0811 | Pnec_0838 | Pnec_0811 | KEGG: pnu:Pnuc_1028 tartrate dehydrogenase. | TIGRFAM: acetolactate synthase, small subunit; PFAM: amino acid-binding ACT domain protein; KEGG: pnu:Pnuc_1062 acetolactate synthase 3 regulatory subunit. | 0.966 |
| Pnec_0838 | ilvC | Pnec_0838 | Pnec_0812 | KEGG: pnu:Pnuc_1028 tartrate dehydrogenase. | Ketol-acid reductoisomerase; Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate. | 0.782 |
| ilvC | Pnec_0337 | Pnec_0812 | Pnec_0337 | Ketol-acid reductoisomerase; Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate. | PFAM: thiamine pyrophosphate protein domain protein TPP-binding; thiamine pyrophosphate protein central region; thiamine pyrophosphate protein TPP binding domain protein; KEGG: rpa:RPA4054 possible acetolactate synthase large subunit; Belongs to the TPP enzyme family. | 0.984 |
| ilvC | Pnec_0810 | Pnec_0812 | Pnec_0810 | Ketol-acid reductoisomerase; Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate. | TIGRFAM: acetolactate synthase, large subunit, biosynthetic type; PFAM: thiamine pyrophosphate protein domain protein TPP-binding; thiamine pyrophosphate protein central region; thiamine pyrophosphate protein TPP binding domain protein; KEGG: pnu:Pnuc_1063 acetolactate synthase, large subunit, biosynthetic type. | 0.995 |
| ilvC | Pnec_0811 | Pnec_0812 | Pnec_0811 | Ketol-acid reductoisomerase; Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate. | TIGRFAM: acetolactate synthase, small subunit; PFAM: amino acid-binding ACT domain protein; KEGG: pnu:Pnuc_1062 acetolactate synthase 3 regulatory subunit. | 0.998 |
| ilvC | Pnec_0838 | Pnec_0812 | Pnec_0838 | Ketol-acid reductoisomerase; Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate. | KEGG: pnu:Pnuc_1028 tartrate dehydrogenase. | 0.782 |