STRINGSTRING
KSE_04580 KSE_04580 glyA2 glyA2 tnaA tnaA KSE_05820 KSE_05820 KSE_08450 KSE_08450 vlmD vlmD KSE_09110 KSE_09110 argD argD KSE_15080 KSE_15080 gcvP gcvP KSE_15520 KSE_15520 KSE_15530 KSE_15530 KSE_16470 KSE_16470 KSE_17040 KSE_17040 KSE_17550 KSE_17550 KSE_19320 KSE_19320 hisC hisC KSE_20960 KSE_20960 KSE_21820 KSE_21820 KSE_21970 KSE_21970 KSE_22030 KSE_22030 KSE_22700 KSE_22700 KSE_23010 KSE_23010 kynU kynU KSE_25120 KSE_25120 KSE_27390 KSE_27390 aspC aspC hemL hemL KSE_34150 KSE_34150 KSE_34790 KSE_34790 KSE_38330 KSE_38330 pat pat KSE_42330 KSE_42330 KSE_42710 KSE_42710 serC serC KSE_46570 KSE_46570 KSE_46580 KSE_46580 metB metB KSE_47640 KSE_47640 dapC dapC glyA3 glyA3 glyA1 glyA1 KSE_51010 KSE_51010 tpa tpa KSE_52680 KSE_52680 gabT gabT sufS sufS KSE_56060 KSE_56060 cobC cobC KSE_57380 KSE_57380 KSE_59440 KSE_59440 KSE_61030 KSE_61030 KSE_61340 KSE_61340 KSE_61520 KSE_61520 KSE_62520 KSE_62520 KSE_62530 KSE_62530 KSE_63100 KSE_63100 KSE_64580 KSE_64580 KSE_65200 KSE_65200 KSE_67160 KSE_67160 KSE_67290 KSE_67290 KSE_67440 KSE_67440 KSE_68020 KSE_68020 KSE_69620 KSE_69620 KSE_70680 KSE_70680 bioF2 bioF2 bioA bioA bioF1 bioF1 kbl kbl metY metY bfmK bfmK
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
KSE_04580Putative cysteine desulfurase; Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L-selenocystine to produce L-alanine. (470 aa)
glyA2Putative serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. (482 aa)
tnaAPutative tryptophanase. (456 aa)
KSE_05820Putative decarboxylase. (488 aa)
KSE_08450Putative aromatic amino acid decarboxylase. (494 aa)
vlmDPutative valine decarboxylase. (542 aa)
KSE_09110Putative aminotransferase. (405 aa)
argDPutative acetylornithine aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily. (400 aa)
KSE_15080Putative GntR family transcriptional regulator. (473 aa)
gcvPPutative glycine dehydrogenase; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. (956 aa)
KSE_15520Belongs to DegT/DnrJ/EryC1/StrS aminotransferase family (IPR000653). (387 aa)
KSE_15530Belongs to DegT/DnrJ/EryC1/StrS aminotransferase family (IPR000653). (393 aa)
KSE_16470Belongs to DegT/DnrJ/EryC1/StrS aminotransferase family (IPR000653). (405 aa)
KSE_17040Putative L-threonine aldolase. (364 aa)
KSE_17550Putative aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (463 aa)
KSE_19320Putative aminotransferase. (403 aa)
hisCPutative histidinol-phosphate aminotransferase; Protein synonym:imidazole acetol-phosphate transaminase; Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily. (366 aa)
KSE_20960Putative aminotransferase. (291 aa)
KSE_21820Putative cysteine desulfurase; Bifunctional protein. (455 aa)
KSE_21970Putative aminotransferase; Belongs to the sulfur carrier protein TusA family. (474 aa)
KSE_22030Putative aromatic amino acid decarboxylase. (455 aa)
KSE_22700Putative aminotransferase. (657 aa)
KSE_23010Putative lyase. (494 aa)
kynUPutative kynureninase; Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively. (409 aa)
KSE_25120Putative glutamate decarboxylase; Belongs to the group II decarboxylase family. (470 aa)
KSE_27390Putative aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (424 aa)
aspCPutative aspartate aminotransferase. (412 aa)
hemLPutative glutamate-1-semialdehyde 2,1-aminomutase; Protein synonym:glutamate-1-semialdehyde aminotransferase. (447 aa)
KSE_34150Putative L-threonine aldolase. (368 aa)
KSE_34790Belongs to DegT/DnrJ/EryC1/StrS aminotransferase family (IPR000653). (402 aa)
KSE_38330Similar to Probable aminotransferase in Mycobacterium tuberculosis (O53870). (389 aa)
patPutative phenylalanine aminotransferase; May catalyze the transamination reaction in phenylalanine biosynthesis; Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. (358 aa)
KSE_42330Putative aminotransferase. (401 aa)
KSE_42710Putative GntR family transcriptional regulator. (474 aa)
serCPutative phosphoserine aminotransferase; Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine; Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily. (372 aa)
KSE_46570Belongs to DegT/DnrJ/EryC1/StrS aminotransferase family (IPR000653). (388 aa)
KSE_46580Belongs to DegT/DnrJ/EryC1/StrS aminotransferase family (IPR000653). (368 aa)
metBPutative cystathionine gamma-synthase; Protein synonym:O-succinylhomoserine (thiol)-lyase. (384 aa)
KSE_47640Putative aminotransferase. (404 aa)
dapCPutative succinyldiaminopimelate aminotransferase. (381 aa)
glyA3Putative serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. (420 aa)
glyA1Putative serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. (422 aa)
KSE_51010Putative cysteine desulfurase. (392 aa)
tpaPutative taurine-pyruvate aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (464 aa)
KSE_52680Putative aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (452 aa)
gabTPutative 4-aminobutyrate aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (446 aa)
sufSPutative cysteine desulfurase; Bifunctional protein; Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. (420 aa)
KSE_56060Similar to Aspartate aminotransferase in Methanobacterium thermoformicicum (Q59569). (360 aa)
cobCPutative threonine-phosphate decarboxylase; Protein synonym:L-threonine-O-3-phosphate decarboxylase. (332 aa)
KSE_57380Putative GntR family transcriptional regulator. (495 aa)
KSE_59440Putative aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (463 aa)
KSE_61030Putative aminotransferase; Similar to Isopenicillin N epimerase in Nocardia lactamdurans (Q03046). (404 aa)
KSE_61340Putative methionine gamma lyase. (416 aa)
KSE_61520Putative GntR family transcriptional regulator. (475 aa)
KSE_62520Putative diaminobutyrate--2-oxoglutarate transaminase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (457 aa)
KSE_62530Putative L-2,4-diaminobutyrate decarboxylase. (488 aa)
KSE_63100Putative L-aspartate-beta-decarboxylase. (550 aa)
KSE_64580Similar to Putative aminotransferase B PatB in Bacillus subtilis (Q08432). (368 aa)
KSE_65200Putative aminotransferase; Similar to HpgT in Streptomyces toyocaensis (Q8KLK4). (435 aa)
KSE_67160Putative aminotransferase; Similar to Isopenicillin N epimerase in Nocardia lactamdurans (Q03046); Similar to Isopenicillin N epimerase in Streptomyces clavuligerus (P18549). (407 aa)
KSE_67290Hypothetical protein. (363 aa)
KSE_67440Putative aminotransferase; Similar to HpgT in Streptomyces toyocaensis (Q8KLK4). (453 aa)
KSE_68020Putative GntR family transcriptional regulator. (438 aa)
KSE_69620Putative aminotransferase. (396 aa)
KSE_70680Putative GntR family transcriptional regulator. (460 aa)
bioF2Putative 8-amino-7-oxononanoate synthase. (415 aa)
bioAPutative adenosylmethionine-8-amino-7-oxononanoate aminotransferase; Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. BioA subfamily. (449 aa)
bioF1Putative 8-amino-7-oxononanoate synthase. (374 aa)
kblPutative 2-amino-3-ketobutyrate coenzyme A ligase; Catalyzes the cleavage of 2-amino-3-ketobutyrate to glycine and acetyl-CoA. (396 aa)
metYPutative O-acetylhomoserine sulfhydrylase; Protein synonym:O-acetylhomoserine (thiol)-lyase. (447 aa)
bfmK5-aminolevulinate synthase. (410 aa)
Your Current Organism:
Kitasatospora setae
NCBI taxonomy Id: 452652
Other names: K. setae KM-6054, Kitasatospora setae KM-6054, Kitasatospora setae str. KM-6054, Kitasatospora setae strain KM-6054
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