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purA purA gltB gltB gltD gltD purH purH guaA guaA adk adk pyrE pyrE BAI95753.1 BAI95753.1 surE surE pyrF pyrF purB purB carA carA carB carB purL purL purS purS purC purC pyrC pyrC gmk gmk amn amn murI murI purF purF glnA glnA glsA glsA purK purK purE purE BAI97150.1 BAI97150.1 guaB guaB pyrB pyrB pyrC-2 pyrC-2 BAI97612.1 BAI97612.1 gcvPB gcvPB gcvPA gcvPA gcvH gcvH gcvT gcvT purM purM purN purN apt apt BAI98098.1 BAI98098.1 BAI98099.1 BAI98099.1 purL-2 purL-2 pyrD pyrD purD purD BAI98304.1 BAI98304.1
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query proteins and first shell of interactors
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second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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experimentally determined
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purAAdenylosuccinate synthase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family. (429 aa)
gltBGlutamate synthase (NADPH) large chain. (1507 aa)
gltDNADPH-dependent glutamate synthase beta chain or related oxidoreductase. (483 aa)
purHPhosphoribosylaminoimidazolecarboxamide formyltransferase; Bifunctional purine biosynthesis protein. (529 aa)
guaAGMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP. (519 aa)
adkAdenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family. (221 aa)
pyrEOrotate phosphoribosyltransferase; Catalyzes the transfer of a ribosyl phosphate group from 5- phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP). (193 aa)
BAI95753.1NAD-specific glutamate dehydrogenase. (1555 aa)
surE5'-nucleotidase; Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates; Belongs to the SurE nucleotidase family. (257 aa)
pyrFOrotidine-5'-phosphate decarboxylase; Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP). (224 aa)
purBAdenylosuccinate lyase; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. (437 aa)
carACarbamoyl-phosphate synthase small chain; Belongs to the CarA family. (389 aa)
carBCarbamoyl-phosphate synthase large chain; Belongs to the CarB family. (1111 aa)
purLPhosphoribosylformylglycinamidine synthase PurL component; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is though [...] (224 aa)
purSPhosphoribosylformylglycinamidine synthase PurS component; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is though [...] (76 aa)
purCPhosphoribosylaminoimidazole-succinocarboxamide synthase; Belongs to the SAICAR synthetase family. (260 aa)
pyrCDihydroorotase; Cyclic amidohydrolase. (441 aa)
gmkGuanylate kinase; Essential for recycling GMP and indirectly, cGMP. (227 aa)
amnAMP nucleosidase; Catalyzes the hydrolysis of the N-glycosidic bond of AMP to form adenine and ribose 5-phosphate. Involved in regulation of AMP concentrations. (484 aa)
murIGlutamate racemase; Provides the (R)-glutamate required for cell wall biosynthesis. (267 aa)
purFAmidophosphoribosyltransferase; Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine. (492 aa)
glnAGlutamine synthetase. (460 aa)
glsAGlutaminase; Belongs to the glutaminase family. (312 aa)
purKPhosphoribosylaminoimidazole carboxylase ATPase subunit; Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR). (356 aa)
purEPhosphoribosylaminoimidazole carboxylase catalytic subunit; Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR). (164 aa)
BAI97150.1GMP synthase - glutamine amidotransferase domain. (233 aa)
guaBIMP dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. (485 aa)
pyrBAspartate carbamoyltransferase catalytic chain; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family. (331 aa)
pyrC-2Dihydroorotase; Cyclic amidohydrolase. (407 aa)
BAI97612.1Conserved hypothetical protein. (215 aa)
gcvPBGlycine dehydrogenase subunit 2. (542 aa)
gcvPAGlycine dehydrogenase subunit 1; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein. (452 aa)
gcvHGlycine cleavage system H protein; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein. (123 aa)
gcvTAminomethyltransferase. (389 aa)
purMPhosphoribosylformylglycinamidine cyclo-ligase; Phosphoribosylaminoimidazole (AIR) synthetase. (364 aa)
purNPhosphoribosylglycinamide formyltransferase; Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate. (315 aa)
aptAdenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. (182 aa)
BAI98098.1Putative allantoinase; Dihydroorotase or related cyclic amidohydrolase. (451 aa)
BAI98099.1Amidase, hydantoinase / carbamoylase family. (416 aa)
purL-2Phosphoribosylformylglycinamidine synthase; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought to assist in [...] (725 aa)
pyrDDihydroorotate oxidase; Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor; Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily. (349 aa)
purDPhosphoribosylamine-glycine ligase; Belongs to the GARS family. (430 aa)
BAI98304.1Putative enzyme, similar to large subunit of carbamoylphosphate synthase protein / carbamoylphosphate synthase large subunit (split gene in MJ). (327 aa)
Your Current Organism:
Sphingobium japonicum
NCBI taxonomy Id: 452662
Other names: S. japonicum UT26S, Sphingobium japonicum UT26, Sphingobium japonicum UT26S, Sphingobium japonicum str. UT26S, Sphingobium japonicum strain UT26S
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