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cobU/cobP cobU/cobP dnaQ dnaQ BAI94874.1 BAI94874.1 rpoN-2 rpoN-2 galU galU BAI95086.1 BAI95086.1 nadD nadD BAI95246.1 BAI95246.1 dnaE dnaE rpoA rpoA BAI95542.1 BAI95542.1 rpoZ rpoZ BAI95626.1 BAI95626.1 dnaN dnaN BAI95830.1 BAI95830.1 rpoC rpoC rpoB rpoB rph rph BAI95977.1 BAI95977.1 dnaE-2 dnaE-2 sua5 sua5 lig lig dnaG dnaG cca cca BAI96422.1 BAI96422.1 pnp pnp BAI96482.1 BAI96482.1 fic-2 fic-2 holB holB ispF ispF moaB moaB dnaE-3 dnaE-3 BAI96574.1 BAI96574.1 BAI96910.1 BAI96910.1 dnaX dnaX glgC glgC ribF ribF cdsA cdsA glmU glmU BAI97262.1 BAI97262.1 BAI97275.1 BAI97275.1 BAI97385.1 BAI97385.1 glnE glnE BAI97564.1 BAI97564.1 mobA mobA manC manC fliA fliA kdsB kdsB dpo1 dpo1 manC-2 manC-2 coaD coaD BAI98209.1 BAI98209.1 dinB dinB dinB-2 dinB-2 glnD glnD cysC cysC cysD cysD
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
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cobU/cobPCobalamin biosynthesis enzyme; Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate. (167 aa)
dnaQDNA polymerase III epsilon subunit; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'- 5' exonuclease. (230 aa)
BAI94874.1DNA polymerase III delta subunit. (345 aa)
rpoN-2RNA polymerase sigma-54 factor; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. (504 aa)
galUUTP-glucose-1-phosphate uridylyltransferase; UDP-glucose pyrophosphorylase. (299 aa)
BAI95086.1FOG: PAS/PAC domain. (161 aa)
nadDNicotinate-nucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD). (209 aa)
BAI95246.1Putative nucleotidyltransferase; DNA polymerase involved in DNA repair. (506 aa)
dnaEDNA polymerase III alpha subunit; DNA polymerase involved in damage-induced mutagenesis and translesion synthesis (TLS). It is not the major replicative DNA polymerase. (1090 aa)
rpoADNA-directed RNA polymerase alpha subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (354 aa)
BAI95542.1Putative diguanylate cyclase; FOG: GGDEF domain / putative membrane protein. (395 aa)
rpoZDNA-directed RNA polymerase subunit K/omega; Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits. (114 aa)
BAI95626.1Putative diguanylate cyclase; FOG: GGDEF domain. (291 aa)
dnaNDNA polymerase III beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] (370 aa)
BAI95830.1Putative phage DNA primase/helicase. (482 aa)
rpoCDNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1418 aa)
rpoBDNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1387 aa)
rphRibonuclease PH; Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation. Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important. Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation. (238 aa)
BAI95977.1Putative nucleotidyltransferase; DNA polymerase involved in DNA repair. (519 aa)
dnaE-2DNA polymerase III alpha subunit; DNA polymerase involved in damage-induced mutagenesis and translesion synthesis (TLS). It is not the major replicative DNA polymerase. (1189 aa)
sua5Putative translation factor; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. (318 aa)
ligATP-dependent DNA ligase. (829 aa)
dnaGDNA primase; RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. (631 aa)
ccatRNA nucleotidyltransferase (CCA-adding enzyme); Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family. (402 aa)
BAI96422.1Conserved hypothetical protein. (464 aa)
pnpPolyribonucleotide nucleotidyltransferase; Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'- direction. (771 aa)
BAI96482.1Mannose-1-phosphate guanylyltransferase; Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis / translation initiation factor 2B, gamma/epsilon subunits (eIF-2Bgamma/eIF-2Bepsilon). (236 aa)
fic-2Cell filamentation protein. (426 aa)
holBDNA polymerase III delta' subunit; ATPase involved in DNA replication. (320 aa)
ispF2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase; Bifunctional enzyme that catalyzes the formation of 4- diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D- erythritol 4-phosphate (MEP) (IspD), and catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C- methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (IspF). (381 aa)
moaBMolybdenum cofactor biosynthesis protein B; May be involved in the biosynthesis of molybdopterin. Belongs to the MoaB/Mog family. (175 aa)
dnaE-3DNA polymerase III alpha subunit. (1178 aa)
BAI96574.1GGDEF-family protein; Sensor histidine kinase / FOG: HAMP domain. (602 aa)
BAI96910.1MobA-related protein. (196 aa)
dnaXDNA polymerase III gamma and tau subunit; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. (536 aa)
glgCGlucose-1-phosphate adenylyltransferase; Involved in the biosynthesis of ADP-glucose, a building block required for the elongation reactions to produce glycogen. Catalyzes the reaction between ATP and alpha-D-glucose 1-phosphate (G1P) to produce pyrophosphate and ADP-Glc; Belongs to the bacterial/plant glucose-1-phosphate adenylyltransferase family. (419 aa)
ribFRiboflavin biosynthesis protein RibF/FAD synthase; Belongs to the ribF family. (312 aa)
cdsAPhosphatidate cytidylyltransferase; CDP-diglyceride synthetase; Belongs to the CDS family. (262 aa)
glmUUDP-N-acetylglucosamine pyrophosphorylase; Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C- terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N- acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5- triphosphate), a reaction catalyzed by the N-terminal domain. (484 aa)
BAI97262.1Putative diguanylate cyclase; FOG: GGDEF domain. (390 aa)
BAI97275.1Putative sugar nucleotidyltransferase. (255 aa)
BAI97385.1DNA polymerase III chi subunit. (149 aa)
glnEGlutamate-ammonia-ligase adenylyltransferase; Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transd [...] (895 aa)
BAI97564.1Hypothetical protein. (265 aa)
mobAMolybdopterin-guanine dinucleotide biosynthesis protein A; Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo-MPT) cofactor (Moco or molybdenum cofactor) to form Mo-molybdopterin guanine dinucleotide (Mo-MGD) cofactor; Belongs to the MobA family. (179 aa)
manCMannose-1-phosphate guanylyltransferase. (319 aa)
fliARNA polymerase sigma factor for flagellar operon FliA; DNA-directed RNA polymerase specialized sigma subunit; Belongs to the sigma-70 factor family. (245 aa)
kdsB3-deoxy-manno-octulosonate cytidylyltransferase; CMP-KDO synthetase. (279 aa)
dpo1DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. (928 aa)
manC-2Mannose-1-phosphate guanylyltransferase; Belongs to the mannose-6-phosphate isomerase type 2 family. (483 aa)
coaDPantetheine-phosphate adenylyltransferase; Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Belongs to the bacterial CoaD family. (170 aa)
BAI98209.1Putative diguanylate cyclase; FOG: GGDEF domain / two-component system, PleD related family, response regulator. (387 aa)
dinBDNA polymerase IV; Nucleotidyltransferase / DNA polymerase involved in DNA repair; remnant. (73 aa)
dinB-2DNA polymerase IV; Nucleotidyltransferase / DNA polymerase involved in DNA repair; remnant. (199 aa)
glnD[protein-PII] uridylyltransferas; Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen assimilation and metabolism. (919 aa)
cysCAdenylylsulfate kinase; Catalyzes the synthesis of activated sulfate. Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN/NodQ subfamily. (637 aa)
cysDSulfate adenylyltransferase subunit 2. (303 aa)
Your Current Organism:
Sphingobium japonicum
NCBI taxonomy Id: 452662
Other names: S. japonicum UT26S, Sphingobium japonicum UT26, Sphingobium japonicum UT26S, Sphingobium japonicum str. UT26S, Sphingobium japonicum strain UT26S
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