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| | atpD | F-type H+-transporting ATPase beta chain; Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits; Belongs to the ATPase alpha/beta chains family. (481 aa) |
| | BAI98567.1 | Oxidoreductase-like protein; NAD-dependent epimerase/dehydratase / 3-beta hydroxysteroid dehydrogenase/isomerase / nucleoside-diphosphate-sugar epimerase. (331 aa) |
| | BAI98549.1 | Permease of the drug/metabolite transporter (DMT) superfamily. (136 aa) |
| | purU-2 | Formyltetrahydrofolate deformylase; Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4). (285 aa) |
| | gcpE | 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase; Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME- 2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate. Belongs to the IspG family. (386 aa) |
| | BAI98347.1 | Putative phosphopantothenoylcysteine synthetase/decarboxylase; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family. (418 aa) |
| | dut | dUTP pyrophosphatase; This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA; Belongs to the dUTPase family. (154 aa) |
| | BAI98339.1 | Uncharacterized protein conserved in bacteria. (165 aa) |
| | exoP | Putative succinoglycan biosynthesis transport protein exoP; ATPase involved in chromosome partitioning. (757 aa) |
| | BAI98326.1 | Putative transmembrane sensor domain. (441 aa) |
| | BAI98313.1 | Putative nucleoside-diphosphate sugar epimerase. (708 aa) |
| | BAI98312.1 | Putative UDP-bacillosamine synthetase; Putative pyridoxal phosphate-dependent enzyme apparently involved in regulation of cell wall biogenesis; Belongs to the DegT/DnrJ/EryC1 family. (411 aa) |
| | BAI98306.1 | Putative glycosyltransferase; Group 1 / N-acetyllactosaminide 3-alpha-galactosyltransferase. (378 aa) |
| | BAI98304.1 | Putative enzyme, similar to large subunit of carbamoylphosphate synthase protein / carbamoylphosphate synthase large subunit (split gene in MJ). (327 aa) |
| | BAI98303.1 | Putative NAD-dependent epimerase/dehydratase; Nucleoside-diphosphate-sugar epimerase / UDP-glucose 4-epimerase. (295 aa) |
| | purD | Phosphoribosylamine-glycine ligase; Belongs to the GARS family. (430 aa) |
| | pyrD | Dihydroorotate oxidase; Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor; Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily. (349 aa) |
| | BAI98225.1 | Putative NAD-dependent epimerase/dehydratase. (265 aa) |
| | kdsA | 2-dehydro-3-deoxyphosphooctonate aldolase; KDO 8-P synthase / 3-deoxy-D-manno-octulosonic acid (KDO) 8-phosphate synthase; Belongs to the KdsA family. (276 aa) |
| | acs | acetyl-CoA synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family. (650 aa) |
| | yagR | Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL/CutL homolog. (738 aa) |
| | pyk | Pyruvate kinase; Belongs to the pyruvate kinase family. (485 aa) |
| | purL-2 | Phosphoribosylformylglycinamidine synthase; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought to assist in [...] (725 aa) |
| | coaD | Pantetheine-phosphate adenylyltransferase; Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Belongs to the bacterial CoaD family. (170 aa) |
| | queA | S-adenosylmethionine:tRNA ribosyltransferase-isomerase; Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA). (344 aa) |
| | accC | Biotin carboxylase; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. (450 aa) |
| | nrdB | Ribonucleoside-diphosphate reductase beta chain; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides; Belongs to the ribonucleoside diphosphate reductase small chain family. (351 aa) |
| | BAI98042.1 | Bleomycin resistance protein / dioxygenase / lactoylglutathione lyase or related lyase. (124 aa) |
| | BAI97998.1 | Bleomycin resistance protein / dioxygenase / lactoylglutathione lyase or related lyase. (176 aa) |
| | BAI97970.1 | Protein involved in cellulose biosynthesis (CelD). (351 aa) |
| | BAI97968.1 | Protein involved in cellulose biosynthesis (CelD). (368 aa) |
| | BAI97967.1 | Putative NAD-dependent epimerase/dehydratase; Nucleoside-diphosphate-sugar epimerase. (331 aa) |
| | kpsF | Sugar isomerase, KpsF/GutQ / putative sugar phosphate isomerase involved in capsule formation; Belongs to the SIS family. GutQ/KpsF subfamily. (335 aa) |
| | kdsB | 3-deoxy-manno-octulosonate cytidylyltransferase; CMP-KDO synthetase. (279 aa) |
| | fliI | Flagellum-specific ATP synthase FliI; Flagellar biosynthesis/type III secretory pathway ATPase. (442 aa) |
| | exsB | Probable transcription regulator ExsB; Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)). Belongs to the QueC family. (230 aa) |
| | queE | Putative organic radical activating enzyme; Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7- deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds. (215 aa) |
| | apt | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. (182 aa) |
| | BAI97883.1 | Putative nucleosidase; 5'-methylthioadenosine (MTA)/S-adenosylhomocycteine (SAH) nucleosidase family protein / nucleoside phosphorylase; bifunctional protein. (200 aa) |
| | wbpX | Glycosyltransferase WbpX; Group 1. (577 aa) |
| | BAI97863.1 | Putative NAD-dependent epimerase/dehydratase; GDP-6-deoxy-D-lyxo-4-hexulose reductase Gmd (EC 4.2.1.47). (299 aa) |
| | gmd | GDP-mannose 4,6-dehydratase; Catalyzes the conversion of GDP-D-mannose to GDP-4-dehydro-6- deoxy-D-mannose. (340 aa) |
| | BAI97860.1 | Putative perosamine synthetase; Putative pyridoxal phosphate-dependent enzyme apparently involved in regulation of cell wall biogenesis; Belongs to the DegT/DnrJ/EryC1 family. (381 aa) |
| | BAI97858.1 | Putative glycosyltransferase; Group 1. (347 aa) |
| | alg2 | Alpha-1,3-mannosyltransferase; Glycosyltransferase, group 1. (345 aa) |
| | BAI97856.1 | Putative acetyltransferase; Isoleucine patch superfamily. (195 aa) |
| | BAI97794.1 | Putative membrane protein. (528 aa) |
| | spoT | Guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. (701 aa) |
| | BAI97758.1 | Conserved hypothetical protein; Putative membrane protein. (633 aa) |
| | purN | Phosphoribosylglycinamide formyltransferase; Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate. (315 aa) |
| | purM | Phosphoribosylformylglycinamidine cyclo-ligase; Phosphoribosylaminoimidazole (AIR) synthetase. (364 aa) |
| | lytB | 4-hydroxy-3-methylbut-2-enyl diphosphate reductase; Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis. Belongs to the IspH family. (315 aa) |
| | murE | UDP-N-acetylmuramoylalanyl-D-glutamate-2, 6-diaminopimelate ligase; Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan. Belongs to the MurCDEF family. MurE subfamily. (480 aa) |
| | murF | UDP-N-acetylmuramoylalanyl-D-glutamyl-2, 6-diaminopimelate--D-alanyl-D-alanine ligase; Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein; Belongs to the MurCDEF family. MurF subfamily. (458 aa) |
| | mraY | phospho-N-acetylmuramoyl-pentapeptide- transferase; First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan; Belongs to the glycosyltransferase 4 family. MraY subfamily. (357 aa) |
| | murD | UDP-N-acetylmuramoylalanine-D-glutamate ligase; Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA). Belongs to the MurCDEF family. (444 aa) |
| | ftsW | Cell division protein FtsW; Belongs to the SEDS family. (400 aa) |
| | murG | Undecaprenyl-PP-MurNAc-pentapeptide-UDPGlcNAc GlcNAc transferase; Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II); Belongs to the glycosyltransferase 28 family. MurG subfamily. (371 aa) |
| | murC | UDP-N-acetylmuramate-alanine ligase; Cell wall formation; Belongs to the MurCDEF family. (473 aa) |
| | murB | UDP-N-acetylmuramate dehydrogenase; Cell wall formation. (315 aa) |
| | ddlA | D-alanine-D-alanine ligase; Cell wall formation; Belongs to the D-alanine--D-alanine ligase family. (321 aa) |
| | dgt | dGTPase; dGTP triphosphohydrolase; Belongs to the dGTPase family. Type 2 subfamily. (395 aa) |
| | gcvPA | Glycine dehydrogenase subunit 1; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein. (452 aa) |
| | BAI97576.1 | Uncharacterized protein conserved in bacteria. (202 aa) |
| | BAI97560.1 | Putative nucleoside-diphosphate-sugar epimerase. (309 aa) |
| | pyrB | Aspartate carbamoyltransferase catalytic chain; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family. (331 aa) |
| | citE-2 | Citrate lyase beta chain; citryl-CoA lyase (EC 4.1.3.34); Belongs to the HpcH/HpaI aldolase family. (271 aa) |
| | atpC | H+-transporting two-sector ATPase delta/epsilon subunit; Produces ATP from ADP in the presence of a proton gradient across the membrane. (84 aa) |
| | atpG | F-type H+-transporting ATPase gamma chain; Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex. (294 aa) |
| | atpA | F-type H+-transporting ATPase alpha chain; Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit. Belongs to the ATPase alpha/beta chains family. (509 aa) |
| | atpH | F-type H+-transporting ATPase oligomycin sensitivity conferral protein; F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation; Belongs to the ATPase delta chain family. (184 aa) |
| | talA | Transaldolase; Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway; Belongs to the transaldolase family. Type 3B subfamily. (217 aa) |
| | BAI97440.1 | Putative NUDIX hydrolase; NTP pyrophosphohydrolase / oxidative damage repair enzyme; remnant. (90 aa) |
| | BAI97427.1 | Putative ribose-phosphate pyrophosphokinase; Phosphoribosylpyrophosphate synthetase; Belongs to the ribose-phosphate pyrophosphokinase family. (294 aa) |
| | BAI97426.1 | Putative thymidine phosphorylase; Glycosyl transferase. (495 aa) |
| | guaB | IMP dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. (485 aa) |
| | ndk | Nucleoside-diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family. (140 aa) |
| | BAI97310.1 | Putative enzyme related to lactoylglutathione lyase. (264 aa) |
| | BAI97291.1 | Conserved hypothetical protein; Involved in the import of queuosine (Q) precursors, required for Q precursor salvage; Belongs to the vitamin uptake transporter (VUT/ECF) (TC 2.A.88) family. Q precursor transporter subfamily. (254 aa) |
| | sucA | 2-oxoglutarate dehydrogenase E1 component. (936 aa) |
| | sucB | 2-oxoglutarate dehydrogenase E2 component; E2 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the second step in the conversion of 2- oxoglutarate to succinyl-CoA and CO(2). (412 aa) |
| | glmU | UDP-N-acetylglucosamine pyrophosphorylase; Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C- terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N- acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5- triphosphate), a reaction catalyzed by the N-terminal domain. (484 aa) |
| | BAI97258.1 | Putative phosphohydrolase. (275 aa) |
| | glmS | Glucosamine-fructose-6-phosphate aminotransferase (isomerizing); Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source. (607 aa) |
| | pyrH | Uridylate kinase; Catalyzes the reversible phosphorylation of UMP to UDP. (241 aa) |
| | dxr | 1-deoxy-D-xylulose-5-phosphate reductoisomerase; Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4- phosphate (MEP); Belongs to the DXR family. (385 aa) |
| | fabZ | 3R-hydroxymyristoyl ACP dehydrase; Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs. (159 aa) |
| | accA | acetyl-CoA carboxylase carboxyl transferase subunit alpha; Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA. (314 aa) |
| | fbaB | Fructose-bisphosphate aldolase; Class I. (300 aa) |
| | BAI96151.1 | Uncharacterized protein conserved in bacteria. (362 aa) |
| | baf | Putative transcriptional regulator; Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis. (260 aa) |
| | tgt | Queuine tRNA-ribosyltransferase; Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, - Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form t [...] (376 aa) |
| | purU | Formyltetrahydrofolate deformylase; Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4). (279 aa) |
| | BAI96214.1 | Putative acyltransferase; Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide acyltransferase (E2) component, or related enzyme; remnant. (95 aa) |
| | anmK | anhydro-N-acetylmuramic acid kinase; Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling; Belongs to the anhydro-N-acetylmuramic acid kinase family. (364 aa) |
| | carA | Carbamoyl-phosphate synthase small chain; Belongs to the CarA family. (389 aa) |
| | carB | Carbamoyl-phosphate synthase large chain; Belongs to the CarB family. (1111 aa) |
| | eno | Enolase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family. (424 aa) |
| | pdhA | Pyruvate dehydrogenase E1 component alpha subunit; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). (358 aa) |
| | pdhB | Pyruvate dehydrogenase E1 component beta subunit; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2. (456 aa) |
| | purL | Phosphoribosylformylglycinamidine synthase PurL component; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is though [...] (224 aa) |
| | purS | Phosphoribosylformylglycinamidine synthase PurS component; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is though [...] (76 aa) |
| | purC | Phosphoribosylaminoimidazole-succinocarboxamide synthase; Belongs to the SAICAR synthetase family. (260 aa) |
| | BAI96332.1 | Protein involved in cellulose biosynthesis (CelD). (335 aa) |
| | BAI96336.1 | Putative exopolysaccharide biosynthesis protein. (503 aa) |
| | BAI96341.1 | Hypothetical protein. (353 aa) |
| | BAI96342.1 | Putative glycosyltransferase; Group 1. (409 aa) |
| | citE | Citrate lyase beta chain; citryl-CoA lyase (EC 4.1.3.34); Belongs to the HpcH/HpaI aldolase family. (278 aa) |
| | gpm | Phosphoglycerate mutase; Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate; Belongs to the phosphoglycerate mutase family. BPG- dependent PGAM subfamily. (228 aa) |
| | purE | Phosphoribosylaminoimidazole carboxylase catalytic subunit; Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR). (164 aa) |
| | purK | Phosphoribosylaminoimidazole carboxylase ATPase subunit; Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR). (356 aa) |
| | ribF | Riboflavin biosynthesis protein RibF/FAD synthase; Belongs to the ribF family. (312 aa) |
| | dxs | 1-deoxy-D-xylulose-5-phosphate synthase; Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D- xylulose-5-phosphate (DXP); Belongs to the transketolase family. DXPS subfamily. (644 aa) |
| | pbp-2 | Membrane carboxypeptidase (penicillin-binding protein). (689 aa) |
| | atpB | F0F1-type ATP synthase subunit a; Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane. (261 aa) |
| | atpE | F0F1-type ATP synthase subunit c; F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. (75 aa) |
| | atpF-2 | F0F1-type ATP synthase subunit b; Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0); Belongs to the ATPase B chain family. (164 aa) |
| | atpF | F0F1-type ATP synthase subunit b; Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0); Belongs to the ATPase B chain family. (208 aa) |
| | ugd-2 | UDP-glucose 6-dehydrogenase. (439 aa) |
| | wecB | UDP-N-acetylglucosamine 2-epimerase; Belongs to the UDP-N-acetylglucosamine 2-epimerase family. (380 aa) |
| | BAI97050.1 | Putative protein-tyrosine kinase; Uncharacterized protein involved in exopolysaccharide biosynthesis. (697 aa) |
| | BAI97047.1 | Uncharacterized protein conserved in bacteria / putative periplasmic protein precursor. (503 aa) |
| | BAI96997.1 | ErfK/YbiS/YcfS/YnhG/uncharacterized protein conserved in bacteria. (220 aa) |
| | folC | Dihydrofolate synthase (EC 6.3.2.12); Belongs to the folylpolyglutamate synthase family. (440 aa) |
| | accD | acetyl-CoA carboxylase carboxyl transferase subunit beta; Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA; Belongs to the AccD/PCCB family. (283 aa) |
| | htrB | Lauroyl/myristoyl acyltransferase. (300 aa) |
| | glk | Glucokinase; Belongs to the bacterial glucokinase family. (321 aa) |
| | zwf | Glucose-6-phosphate 1-dehydrogenase; Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone. (486 aa) |
| | pgl | 6-phosphogluconolactonase; Hydrolysis of 6-phosphogluconolactone to 6-phosphogluconate. (229 aa) |
| | pdhC-2 | Pyruvate dehydrogenase E2 component; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). (427 aa) |
| | BAI96897.1 | acyl-CoA hydrolase. (135 aa) |
| | pdhD | Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, or related enzyme. (467 aa) |
| | BAI96781.1 | Glycosyltransferase involved in cell wall biogenesis. (368 aa) |
| | mtgA | Monofunctional biosynthetic peptidoglycan transglycosylase; Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors; Belongs to the glycosyltransferase 51 family. (232 aa) |
| | ugd | UDP-glucose 6-dehydrogenase. (447 aa) |
| | exoQ | Exopolysaccharide production protein; Lipid A core - O-antigen ligase or related enzyme. (464 aa) |
| | BAI96757.1 | Putative glycosyltransferase; Teichoic acid biosynthesis protein; Belongs to the glycosyltransferase 26 family. (274 aa) |
| | pdhA-2 | Pyruvate/2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit. (323 aa) |
| | BAI96699.1 | Putative acyltransferase; Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide acyltransferase (E2) component, or related enzyme; remnant. (79 aa) |
| | BAI96634.1 | Conjugal transfer protein TrbN / soluble lytic murein transglycosylase or related regulatory protein (LysM/invasin domain). (178 aa) |
| | rodA | Rod shape determining protein; Peptidoglycan polymerase that is essential for cell wall elongation; Belongs to the SEDS family. MrdB/RodA subfamily. (370 aa) |
| | mrdA | Penicillin binding protein 2; Cell division protein FtsI / peptidoglycan glycosyltransferase. (689 aa) |
| | nudH | Putative (di)nucleoside polyphosphate hydrolase; Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage; Belongs to the Nudix hydrolase family. RppH subfamily. (162 aa) |
| | purF | Amidophosphoribosyltransferase; Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine. (492 aa) |
| | ispE | 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase; Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol. (299 aa) |
| | murI | Glutamate racemase; Provides the (R)-glutamate required for cell wall biosynthesis. (267 aa) |
| | pgi | Glucose-6-phosphate isomerase; Belongs to the GPI family. (501 aa) |
| | amn | AMP nucleosidase; Catalyzes the hydrolysis of the N-glycosidic bond of AMP to form adenine and ribose 5-phosphate. Involved in regulation of AMP concentrations. (484 aa) |
| | algH | Putative transcriptional regulator; Belongs to the UPF0301 (AlgH) family. (186 aa) |
| | ispF | 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase; Bifunctional enzyme that catalyzes the formation of 4- diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D- erythritol 4-phosphate (MEP) (IspD), and catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C- methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (IspF). (381 aa) |
| | mazG | Nucleoside triphosphate pyrophosphohydrolase. (263 aa) |
| | tmk | dTMP kinase; Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis; Belongs to the thymidylate kinase family. (213 aa) |
| | dacA | D-alanyl-D-alanine carboxypeptidase; Penicillin binding protein 5/6; Belongs to the peptidase S11 family. (387 aa) |
| | BAI96481.1 | Putative phosphotransferase related to Ser/Thr protein kinases. (332 aa) |
| | pyrG | CTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates. (544 aa) |
| | tpiA | Triosephosphate isomerase (TIM); Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P); Belongs to the triosephosphate isomerase family. (246 aa) |
| | mltG | Putative aminodeoxychorismate lyase; Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation. (323 aa) |
| | BAI96424.1 | Putative glycosyltransferase; Group 1. (383 aa) |
| | BAI96412.1 | Lysozyme M1 (1,4-beta-N-acetylmuramidase). (221 aa) |
| | cdd | Cytidine deaminase; This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis; Belongs to the cytidine and deoxycytidylate deaminase family. (152 aa) |
| | dcd | dCTP deaminase; Catalyzes the deamination of dCTP to dUTP. (184 aa) |
| | gmk | Guanylate kinase; Essential for recycling GMP and indirectly, cGMP. (227 aa) |
| | BAI96382.1 | Putative peptidoglycan binding domain protein; Uncharacterized protein conserved in bacteria. (484 aa) |
| | BAI96380.1 | Hypothetical protein. (248 aa) |
| | BAI96348.1 | Conserved hypothetical protein; Uncharacterized membrane protein, putative virulence factor. (450 aa) |
| | BAI96346.1 | Group 2 / glycosyltransferase, probably involved in cell wall biogenesis / two-component system sensor histidine kinase/response regulator, hybrid ('one component system'). (377 aa) |
| | acs-2 | acetyl-CoA synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family. (650 aa) |
| | BAI98909.1 | Cellulose synthase protein C precursor; FOG: TPR repeat. (1125 aa) |
| | BAI98908.1 | Putative cellulose synthase; UDP-forming / glycosyltransferase, probably involved in cell wall biogenesis. (1441 aa) |
| | mipA | MltA-interacting MipA; Outer membrane protein V. (281 aa) |
| | linEb | 2,6-dichloro-p-hydroquinone 1,2-dioxygenase LinEb; Gamma-hexachlorocyclohexane degradation. (320 aa) |
| | BAI98824.1 | Hypothetical protein. (207 aa) |
| | BAI98803.1 | Putative iron-sulfur cluster binding protein. (446 aa) |
| | BAI98696.1 | Phosphoglycerate/bisphosphoglycerate mutase family protein. (187 aa) |
| | BAI98580.1 | PST family polysaccharide transporter; Membrane protein involved in the export of O-antigen and teichoic acid / polysaccharide biosynthesis protein. (486 aa) |
| | BAI98574.1 | Putative glycosyltransferase; Group 1. (396 aa) |
| | BAI98572.1 | Putative glycerol-3-phosphate dehydrogenase; FAD-dependent oxidoreductase. (387 aa) |
| | BAI98571.1 | Glycosyltransferase, family 2 / glycosyltransferase involved in cell wall biogenesis. (325 aa) |
| | BAI98569.1 | Hypothetical protein. (574 aa) |
| | pgk | 3-phosphoglycerate kinase; Belongs to the phosphoglycerate kinase family. (400 aa) |
| | gapD | Glyceraldehyde-3-phosphate dehydrogenase; Type I; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family. (336 aa) |
| | tktA | Transketolase; Belongs to the transketolase family. (655 aa) |
| | pdhC | Pyruvate dehydrogenase E2 component; Dihydrolipoamide acetyltransferase. (415 aa) |
| | bkdA1 | 2-oxoisovalerate dehydrogenase alpha subunit. (431 aa) |
| | thyA | Thymidylate synthase; Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by- product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis. (311 aa) |
| | purB | Adenylosuccinate lyase; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. (437 aa) |
| | BAI96117.1 | Hypothetical protein. (110 aa) |
| | pyrF | Orotidine-5'-phosphate decarboxylase; Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP). (224 aa) |
| | surE | 5'-nucleotidase; Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates; Belongs to the SurE nucleotidase family. (257 aa) |
| | BAI96083.1 | Uncharacterized protein conserved in bacteria / metallophosphoesterase. (287 aa) |
| | BAI96016.1 | Conserved hypothetical protein. (265 aa) |
| | rlpA | Rare lipoprotein A; Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides. (190 aa) |
| | rfbB-2 | dTDP-glucose 4,6-dehydratase; Nucleoside-diphosphate-sugar epimerase. (353 aa) |
| | rfbB | dTDP-glucose 4,6-dehydratase; Nucleoside-diphosphate-sugar epimerase. (357 aa) |
| | galE | UDP-glucose 4-epimerase; Nucleoside-diphosphate-sugar epimerase. (375 aa) |
| | BAI95948.1 | Putative phosphoglycerate mutase; Fructose-2,6-bisphosphatase. (208 aa) |
| | BAI95939.1 | Hypothetical protein. (134 aa) |
| | BAI95938.1 | FOG: TPR repeat. (326 aa) |
| | BAI95882.1 | N-acetylmuramoyl-L-alanine amidase; Negative regulator of beta-lactamase expression. (232 aa) |
| | BAI95870.1 | NTP pyrophosphohydrolase including oxidative damage repair enzyme. (180 aa) |
| | mltA | Membrane-bound lytic murein transglycosylase A. (419 aa) |
| | mviN | Integral membrane protein MviN; Involved in peptidoglycan biosynthesis. Transports lipid- linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane. (529 aa) |
| | murA | UDP-N-acetylglucosamine 1-carboxyvinyltransferase; Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine; Belongs to the EPSP synthase family. MurA subfamily. (427 aa) |
| | mrcA | Penicillin binding protein 1A; Bifunctional protein; peptidoglycan glycosyltransferase / membrane carboxypeptidase. (845 aa) |
| | amiA | N-acetylmuramoyl-L-alanine amidase. (334 aa) |
| | BAI95582.1 | Putative glycosyltransferase; Group 1. (408 aa) |
| | BAI95579.1 | Lipid A core - O-antigen ligase or related enzyme. (453 aa) |
| | glpK | Glycerol kinase; Belongs to the FGGY kinase family. (488 aa) |
| | glpA | Glycerol-3-phosphate dehydrogenase; Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family. (502 aa) |
| | BAI95548.1 | Glycosyltransferase, probably involved in cell wall biogenesis. (648 aa) |
| | ykvM | 7-cyano-7-deazaguanine reductase; Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1). Belongs to the GTP cyclohydrolase I family. QueF type 1 subfamily. (157 aa) |
| | BAI95519.1 | Conserved hypothetical protein; Involved in the import of queuosine (Q) precursors, required for Q precursor salvage; Belongs to the vitamin uptake transporter (VUT/ECF) (TC 2.A.88) family. Q precursor transporter subfamily. (223 aa) |
| | pyrE | Orotate phosphoribosyltransferase; Catalyzes the transfer of a ribosyl phosphate group from 5- phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP). (193 aa) |
| | adk | Adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family. (221 aa) |
| | BAI95417.1 | acetyl-CoA hydrolase. (503 aa) |
| | guaA | GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP. (519 aa) |
| | prsA-2 | Ribose-phosphate pyrophosphokinase; Phosphoribosylpyrophosphate synthetase; Belongs to the ribose-phosphate pyrophosphokinase family. (302 aa) |
| | BAI95312.1 | Putative thymidine phosphorylase. (512 aa) |
| | virB1 | Type IV secretion system protein VirB1. (221 aa) |
| | prsA | Ribose-phosphate pyrophosphokinase; Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib- 5-P); Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily. (311 aa) |
| | gpsA | Glycerol-3-phosphate dehydrogenase (NAD(P)+); Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family. (323 aa) |
| | queG | Putative Fe-S protein; Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr); Belongs to the QueG family. (340 aa) |
| | BAI95139.1 | Conserved hypothetical protein. (616 aa) |
| | purH | Phosphoribosylaminoimidazolecarboxamide formyltransferase; Bifunctional purine biosynthesis protein. (529 aa) |
| | rpe | Ribulose-phosphate 3-epimerase/pentose-5-phosphate-3-epimerase. (220 aa) |
| | BAI95084.1 | Uncharacterized protein conserved in bacteria. (588 aa) |
| | galU | UTP-glucose-1-phosphate uridylyltransferase; UDP-glucose pyrophosphorylase. (299 aa) |
| | bacA | Undecaprenyl-diphosphatase; Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin; Belongs to the UppP family. (269 aa) |
| | purA | Adenylosuccinate synthase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family. (429 aa) |
| | BAI94952.1 | Conserved hypothetical protein. (176 aa) |
| | BAI94904.1 | Membrane protein involved in the export of O-antigen and teichoic acid. (497 aa) |
| | BAI94903.1 | FOG: CBS domain. (142 aa) |
| | BAI94901.1 | acyl-CoA hydrolase. (125 aa) |
| | BAI94891.1 | FOG: Ankyrin repeat. (203 aa) |
| | pbp | Membrane carboxypeptidase (penicillin-binding protein). (689 aa) |
| | coaE | dephospho-CoA kinase; Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; Belongs to the CoaE family. (197 aa) |
