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| | bacA | Undecaprenyl-diphosphatase; Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin; Belongs to the UppP family. (269 aa) |
| | atpF-2 | F0F1-type ATP synthase subunit b; Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0); Belongs to the ATPase B chain family. (164 aa) |
| | atpF | F0F1-type ATP synthase subunit b; Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0); Belongs to the ATPase B chain family. (208 aa) |
| | ugd-2 | UDP-glucose 6-dehydrogenase. (439 aa) |
| | BAI97050.1 | Putative protein-tyrosine kinase; Uncharacterized protein involved in exopolysaccharide biosynthesis. (697 aa) |
| | BAI97047.1 | Uncharacterized protein conserved in bacteria / putative periplasmic protein precursor. (503 aa) |
| | BAI96997.1 | ErfK/YbiS/YcfS/YnhG/uncharacterized protein conserved in bacteria. (220 aa) |
| | folC | Dihydrofolate synthase (EC 6.3.2.12); Belongs to the folylpolyglutamate synthase family. (440 aa) |
| | accD | acetyl-CoA carboxylase carboxyl transferase subunit beta; Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA; Belongs to the AccD/PCCB family. (283 aa) |
| | htrB | Lauroyl/myristoyl acyltransferase. (300 aa) |
| | pdhC-2 | Pyruvate dehydrogenase E2 component; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). (427 aa) |
| | BAI96781.1 | Glycosyltransferase involved in cell wall biogenesis. (368 aa) |
| | mtgA | Monofunctional biosynthetic peptidoglycan transglycosylase; Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors; Belongs to the glycosyltransferase 51 family. (232 aa) |
| | ugd | UDP-glucose 6-dehydrogenase. (447 aa) |
| | exoQ | Exopolysaccharide production protein; Lipid A core - O-antigen ligase or related enzyme. (464 aa) |
| | BAI96757.1 | Putative glycosyltransferase; Teichoic acid biosynthesis protein; Belongs to the glycosyltransferase 26 family. (274 aa) |
| | pdhA-2 | Pyruvate/2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit. (323 aa) |
| | rodA | Rod shape determining protein; Peptidoglycan polymerase that is essential for cell wall elongation; Belongs to the SEDS family. MrdB/RodA subfamily. (370 aa) |
| | mrdA | Penicillin binding protein 2; Cell division protein FtsI / peptidoglycan glycosyltransferase. (689 aa) |
| | purF | Amidophosphoribosyltransferase; Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine. (492 aa) |
| | murI | Glutamate racemase; Provides the (R)-glutamate required for cell wall biosynthesis. (267 aa) |
| | amn | AMP nucleosidase; Catalyzes the hydrolysis of the N-glycosidic bond of AMP to form adenine and ribose 5-phosphate. Involved in regulation of AMP concentrations. (484 aa) |
| | algH | Putative transcriptional regulator; Belongs to the UPF0301 (AlgH) family. (186 aa) |
| | tmk | dTMP kinase; Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis; Belongs to the thymidylate kinase family. (213 aa) |
| | dacA | D-alanyl-D-alanine carboxypeptidase; Penicillin binding protein 5/6; Belongs to the peptidase S11 family. (387 aa) |
| | BAI96481.1 | Putative phosphotransferase related to Ser/Thr protein kinases. (332 aa) |
| | pyrG | CTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates. (544 aa) |
| | mltG | Putative aminodeoxychorismate lyase; Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation. (323 aa) |
| | BAI96424.1 | Putative glycosyltransferase; Group 1. (383 aa) |
| | dcd | dCTP deaminase; Catalyzes the deamination of dCTP to dUTP. (184 aa) |
| | BAI96382.1 | Putative peptidoglycan binding domain protein; Uncharacterized protein conserved in bacteria. (484 aa) |
| | BAI96380.1 | Hypothetical protein. (248 aa) |
| | BAI96348.1 | Conserved hypothetical protein; Uncharacterized membrane protein, putative virulence factor. (450 aa) |
| | BAI96346.1 | Group 2 / glycosyltransferase, probably involved in cell wall biogenesis / two-component system sensor histidine kinase/response regulator, hybrid ('one component system'). (377 aa) |
| | BAI96342.1 | Putative glycosyltransferase; Group 1. (409 aa) |
| | BAI96341.1 | Hypothetical protein. (353 aa) |
| | BAI96336.1 | Putative exopolysaccharide biosynthesis protein. (503 aa) |
| | BAI96332.1 | Protein involved in cellulose biosynthesis (CelD). (335 aa) |
| | purC | Phosphoribosylaminoimidazole-succinocarboxamide synthase; Belongs to the SAICAR synthetase family. (260 aa) |
| | purS | Phosphoribosylformylglycinamidine synthase PurS component; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is though [...] (76 aa) |
| | purL | Phosphoribosylformylglycinamidine synthase PurL component; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is though [...] (224 aa) |
| | pdhB | Pyruvate dehydrogenase E1 component beta subunit; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2. (456 aa) |
| | pdhA | Pyruvate dehydrogenase E1 component alpha subunit; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). (358 aa) |
| | carB | Carbamoyl-phosphate synthase large chain; Belongs to the CarB family. (1111 aa) |
| | carA | Carbamoyl-phosphate synthase small chain; Belongs to the CarA family. (389 aa) |
| | BAI96214.1 | Putative acyltransferase; Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide acyltransferase (E2) component, or related enzyme; remnant. (95 aa) |
| | purU | Formyltetrahydrofolate deformylase; Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4). (279 aa) |
| | tgt | Queuine tRNA-ribosyltransferase; Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, - Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form t [...] (376 aa) |
| | baf | Putative transcriptional regulator; Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis. (260 aa) |
| | BAI96151.1 | Uncharacterized protein conserved in bacteria. (362 aa) |
| | bkdA1 | 2-oxoisovalerate dehydrogenase alpha subunit. (431 aa) |
| | thyA | Thymidylate synthase; Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by- product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis. (311 aa) |
| | purB | Adenylosuccinate lyase; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. (437 aa) |
| | pyrF | Orotidine-5'-phosphate decarboxylase; Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP). (224 aa) |
| | BAI96083.1 | Uncharacterized protein conserved in bacteria / metallophosphoesterase. (287 aa) |
| | rfbB-2 | dTDP-glucose 4,6-dehydratase; Nucleoside-diphosphate-sugar epimerase. (353 aa) |
| | rfbB | dTDP-glucose 4,6-dehydratase; Nucleoside-diphosphate-sugar epimerase. (357 aa) |
| | galE | UDP-glucose 4-epimerase; Nucleoside-diphosphate-sugar epimerase. (375 aa) |
| | BAI95939.1 | Hypothetical protein. (134 aa) |
| | BAI95938.1 | FOG: TPR repeat. (326 aa) |
| | mviN | Integral membrane protein MviN; Involved in peptidoglycan biosynthesis. Transports lipid- linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane. (529 aa) |
| | murA | UDP-N-acetylglucosamine 1-carboxyvinyltransferase; Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine; Belongs to the EPSP synthase family. MurA subfamily. (427 aa) |
| | mrcA | Penicillin binding protein 1A; Bifunctional protein; peptidoglycan glycosyltransferase / membrane carboxypeptidase. (845 aa) |
| | BAI95582.1 | Putative glycosyltransferase; Group 1. (408 aa) |
| | BAI95579.1 | Lipid A core - O-antigen ligase or related enzyme. (453 aa) |
| | ykvM | 7-cyano-7-deazaguanine reductase; Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1). Belongs to the GTP cyclohydrolase I family. QueF type 1 subfamily. (157 aa) |
| | BAI95519.1 | Conserved hypothetical protein; Involved in the import of queuosine (Q) precursors, required for Q precursor salvage; Belongs to the vitamin uptake transporter (VUT/ECF) (TC 2.A.88) family. Q precursor transporter subfamily. (223 aa) |
| | pyrE | Orotate phosphoribosyltransferase; Catalyzes the transfer of a ribosyl phosphate group from 5- phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP). (193 aa) |
| | adk | Adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family. (221 aa) |
| | guaA | GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP. (519 aa) |
| | prsA-2 | Ribose-phosphate pyrophosphokinase; Phosphoribosylpyrophosphate synthetase; Belongs to the ribose-phosphate pyrophosphokinase family. (302 aa) |
| | prsA | Ribose-phosphate pyrophosphokinase; Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib- 5-P); Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily. (311 aa) |
| | gpsA | Glycerol-3-phosphate dehydrogenase (NAD(P)+); Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family. (323 aa) |
| | queG | Putative Fe-S protein; Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr); Belongs to the QueG family. (340 aa) |
| | BAI95139.1 | Conserved hypothetical protein. (616 aa) |
| | purH | Phosphoribosylaminoimidazolecarboxamide formyltransferase; Bifunctional purine biosynthesis protein. (529 aa) |
| | atpE | F0F1-type ATP synthase subunit c; F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. (75 aa) |
| | purA | Adenylosuccinate synthase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family. (429 aa) |
| | BAI94904.1 | Membrane protein involved in the export of O-antigen and teichoic acid. (497 aa) |
| | pbp | Membrane carboxypeptidase (penicillin-binding protein). (689 aa) |
| | coaE | dephospho-CoA kinase; Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; Belongs to the CoaE family. (197 aa) |
| | acs-2 | acetyl-CoA synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family. (650 aa) |
| | mipA | MltA-interacting MipA; Outer membrane protein V. (281 aa) |
| | BAI98824.1 | Hypothetical protein. (207 aa) |
| | BAI98803.1 | Putative iron-sulfur cluster binding protein. (446 aa) |
| | BAI98580.1 | PST family polysaccharide transporter; Membrane protein involved in the export of O-antigen and teichoic acid / polysaccharide biosynthesis protein. (486 aa) |
| | BAI98574.1 | Putative glycosyltransferase; Group 1. (396 aa) |
| | BAI98571.1 | Glycosyltransferase, family 2 / glycosyltransferase involved in cell wall biogenesis. (325 aa) |
| | BAI98569.1 | Hypothetical protein. (574 aa) |
| | BAI98567.1 | Oxidoreductase-like protein; NAD-dependent epimerase/dehydratase / 3-beta hydroxysteroid dehydrogenase/isomerase / nucleoside-diphosphate-sugar epimerase. (331 aa) |
| | BAI98549.1 | Permease of the drug/metabolite transporter (DMT) superfamily. (136 aa) |
| | purU-2 | Formyltetrahydrofolate deformylase; Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4). (285 aa) |
| | BAI98347.1 | Putative phosphopantothenoylcysteine synthetase/decarboxylase; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family. (418 aa) |
| | dut | dUTP pyrophosphatase; This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA; Belongs to the dUTPase family. (154 aa) |
| | BAI98339.1 | Uncharacterized protein conserved in bacteria. (165 aa) |
| | exoP | Putative succinoglycan biosynthesis transport protein exoP; ATPase involved in chromosome partitioning. (757 aa) |
| | BAI98326.1 | Putative transmembrane sensor domain. (441 aa) |
| | BAI98313.1 | Putative nucleoside-diphosphate sugar epimerase. (708 aa) |
| | BAI98312.1 | Putative UDP-bacillosamine synthetase; Putative pyridoxal phosphate-dependent enzyme apparently involved in regulation of cell wall biogenesis; Belongs to the DegT/DnrJ/EryC1 family. (411 aa) |
| | BAI98306.1 | Putative glycosyltransferase; Group 1 / N-acetyllactosaminide 3-alpha-galactosyltransferase. (378 aa) |
| | BAI98304.1 | Putative enzyme, similar to large subunit of carbamoylphosphate synthase protein / carbamoylphosphate synthase large subunit (split gene in MJ). (327 aa) |
| | BAI98303.1 | Putative NAD-dependent epimerase/dehydratase; Nucleoside-diphosphate-sugar epimerase / UDP-glucose 4-epimerase. (295 aa) |
| | purD | Phosphoribosylamine-glycine ligase; Belongs to the GARS family. (430 aa) |
| | pyrD | Dihydroorotate oxidase; Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor; Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily. (349 aa) |
| | BAI98225.1 | Putative NAD-dependent epimerase/dehydratase. (265 aa) |
| | kdsA | 2-dehydro-3-deoxyphosphooctonate aldolase; KDO 8-P synthase / 3-deoxy-D-manno-octulosonic acid (KDO) 8-phosphate synthase; Belongs to the KdsA family. (276 aa) |
| | acs | acetyl-CoA synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family. (650 aa) |
| | yagR | Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL/CutL homolog. (738 aa) |
| | purL-2 | Phosphoribosylformylglycinamidine synthase; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought to assist in [...] (725 aa) |
| | coaD | Pantetheine-phosphate adenylyltransferase; Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Belongs to the bacterial CoaD family. (170 aa) |
| | queA | S-adenosylmethionine:tRNA ribosyltransferase-isomerase; Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA). (344 aa) |
| | accC | Biotin carboxylase; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. (450 aa) |
| | nrdB | Ribonucleoside-diphosphate reductase beta chain; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides; Belongs to the ribonucleoside diphosphate reductase small chain family. (351 aa) |
| | BAI97970.1 | Protein involved in cellulose biosynthesis (CelD). (351 aa) |
| | BAI97968.1 | Protein involved in cellulose biosynthesis (CelD). (368 aa) |
| | BAI97967.1 | Putative NAD-dependent epimerase/dehydratase; Nucleoside-diphosphate-sugar epimerase. (331 aa) |
| | kdsB | 3-deoxy-manno-octulosonate cytidylyltransferase; CMP-KDO synthetase. (279 aa) |
| | fliI | Flagellum-specific ATP synthase FliI; Flagellar biosynthesis/type III secretory pathway ATPase. (442 aa) |
| | exsB | Probable transcription regulator ExsB; Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)). Belongs to the QueC family. (230 aa) |
| | queE | Putative organic radical activating enzyme; Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7- deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds. (215 aa) |
| | apt | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. (182 aa) |
| | wbpX | Glycosyltransferase WbpX; Group 1. (577 aa) |
| | BAI97863.1 | Putative NAD-dependent epimerase/dehydratase; GDP-6-deoxy-D-lyxo-4-hexulose reductase Gmd (EC 4.2.1.47). (299 aa) |
| | BAI97860.1 | Putative perosamine synthetase; Putative pyridoxal phosphate-dependent enzyme apparently involved in regulation of cell wall biogenesis; Belongs to the DegT/DnrJ/EryC1 family. (381 aa) |
| | BAI97858.1 | Putative glycosyltransferase; Group 1. (347 aa) |
| | alg2 | Alpha-1,3-mannosyltransferase; Glycosyltransferase, group 1. (345 aa) |
| | BAI97856.1 | Putative acetyltransferase; Isoleucine patch superfamily. (195 aa) |
| | BAI97794.1 | Putative membrane protein. (528 aa) |
| | BAI97758.1 | Conserved hypothetical protein; Putative membrane protein. (633 aa) |
| | purN | Phosphoribosylglycinamide formyltransferase; Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate. (315 aa) |
| | purM | Phosphoribosylformylglycinamidine cyclo-ligase; Phosphoribosylaminoimidazole (AIR) synthetase. (364 aa) |
| | murE | UDP-N-acetylmuramoylalanyl-D-glutamate-2, 6-diaminopimelate ligase; Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan. Belongs to the MurCDEF family. MurE subfamily. (480 aa) |
| | murF | UDP-N-acetylmuramoylalanyl-D-glutamyl-2, 6-diaminopimelate--D-alanyl-D-alanine ligase; Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein; Belongs to the MurCDEF family. MurF subfamily. (458 aa) |
| | mraY | phospho-N-acetylmuramoyl-pentapeptide- transferase; First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan; Belongs to the glycosyltransferase 4 family. MraY subfamily. (357 aa) |
| | murD | UDP-N-acetylmuramoylalanine-D-glutamate ligase; Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA). Belongs to the MurCDEF family. (444 aa) |
| | ftsW | Cell division protein FtsW; Belongs to the SEDS family. (400 aa) |
| | murG | Undecaprenyl-PP-MurNAc-pentapeptide-UDPGlcNAc GlcNAc transferase; Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II); Belongs to the glycosyltransferase 28 family. MurG subfamily. (371 aa) |
| | murC | UDP-N-acetylmuramate-alanine ligase; Cell wall formation; Belongs to the MurCDEF family. (473 aa) |
| | murB | UDP-N-acetylmuramate dehydrogenase; Cell wall formation. (315 aa) |
| | ddlA | D-alanine-D-alanine ligase; Cell wall formation; Belongs to the D-alanine--D-alanine ligase family. (321 aa) |
| | BAI97576.1 | Uncharacterized protein conserved in bacteria. (202 aa) |
| | BAI97560.1 | Putative nucleoside-diphosphate-sugar epimerase. (309 aa) |
| | pyrB | Aspartate carbamoyltransferase catalytic chain; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family. (331 aa) |
| | atpC | H+-transporting two-sector ATPase delta/epsilon subunit; Produces ATP from ADP in the presence of a proton gradient across the membrane. (84 aa) |
| | atpD | F-type H+-transporting ATPase beta chain; Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits; Belongs to the ATPase alpha/beta chains family. (481 aa) |
| | atpG | F-type H+-transporting ATPase gamma chain; Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex. (294 aa) |
| | atpA | F-type H+-transporting ATPase alpha chain; Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit. Belongs to the ATPase alpha/beta chains family. (509 aa) |
| | atpH | F-type H+-transporting ATPase oligomycin sensitivity conferral protein; F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation; Belongs to the ATPase delta chain family. (184 aa) |
| | BAI97440.1 | Putative NUDIX hydrolase; NTP pyrophosphohydrolase / oxidative damage repair enzyme; remnant. (90 aa) |
| | BAI97427.1 | Putative ribose-phosphate pyrophosphokinase; Phosphoribosylpyrophosphate synthetase; Belongs to the ribose-phosphate pyrophosphokinase family. (294 aa) |
| | guaB | IMP dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. (485 aa) |
| | ndk | Nucleoside-diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family. (140 aa) |
| | BAI97291.1 | Conserved hypothetical protein; Involved in the import of queuosine (Q) precursors, required for Q precursor salvage; Belongs to the vitamin uptake transporter (VUT/ECF) (TC 2.A.88) family. Q precursor transporter subfamily. (254 aa) |
| | glmU | UDP-N-acetylglucosamine pyrophosphorylase; Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C- terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N- acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5- triphosphate), a reaction catalyzed by the N-terminal domain. (484 aa) |
| | BAI97258.1 | Putative phosphohydrolase. (275 aa) |
| | glmS | Glucosamine-fructose-6-phosphate aminotransferase (isomerizing); Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source. (607 aa) |
| | pyrH | Uridylate kinase; Catalyzes the reversible phosphorylation of UMP to UDP. (241 aa) |
| | fabZ | 3R-hydroxymyristoyl ACP dehydrase; Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs. (159 aa) |
| | accA | acetyl-CoA carboxylase carboxyl transferase subunit alpha; Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA. (314 aa) |
| | purE | Phosphoribosylaminoimidazole carboxylase catalytic subunit; Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR). (164 aa) |
| | purK | Phosphoribosylaminoimidazole carboxylase ATPase subunit; Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR). (356 aa) |
| | ribF | Riboflavin biosynthesis protein RibF/FAD synthase; Belongs to the ribF family. (312 aa) |
| | dxs | 1-deoxy-D-xylulose-5-phosphate synthase; Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D- xylulose-5-phosphate (DXP); Belongs to the transketolase family. DXPS subfamily. (644 aa) |
| | pbp-2 | Membrane carboxypeptidase (penicillin-binding protein). (689 aa) |
| | atpB | F0F1-type ATP synthase subunit a; Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane. (261 aa) |
