STRINGSTRING
linB linB linK linK linL linL linM linM luxR luxR arsR arsR luxR-2 luxR-2 luxR-3 luxR-3 rpsL rpsL mhpE/xylK mhpE/xylK arsR-2 arsR-2 linX linX tfdE tfdE lysC lysC luxR-4 luxR-4 linF linF linEb linEb linJ linJ linH linH
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
linB1,3,4,6-tetrachloro-1,4-cyclohexadiene hydrolase LinB; Catalyzes hydrolytic cleavage of carbon-halogen bonds in halogenated aliphatic compounds, leading to the formation of the corresponding primary alcohols, halide ions and protons. Has a broad substrate specificity since not only monochloroalkanes (C3 to C10) but also dichloroalkanes (> C3), bromoalkanes, and chlorinated aliphatic alcohols are good substrates. Shows almost no activity with 1,2-dichloroethane, but very high activity with the brominated analog. Is involved in the degradation of the important environmental pollutant gam [...] (296 aa)
linKABC-type transport system involved in resistance to organic solvents, permease component / gamma-hexachlorocyclohexane degradation. (376 aa)
linLABC-type transport system involved in resistance to organic solvents, ATPase component / gamma-hexachlorocyclohexane degradation. (282 aa)
linMABC-type transport system involved in resistance to organic solvents, periplasmic component / gamma-hexachlorocyclohexane degradation. (320 aa)
luxRLuxR-family transcriptional regulator; DNA-binding HTH domain-containing protein. (265 aa)
arsRArsR-family transcriptional regulator. (139 aa)
luxR-2LuxR-family transcriptional regulator; DNA-binding HTH domain-containing protein. (248 aa)
luxR-3LuxR-family transcriptional regulator; DNA-binding HTH domain-containing protein. (253 aa)
rpsLRibosomal protein S12; Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit. (123 aa)
mhpE/xylK4-hydroxy 2-oxovalerate aldolase; Catalyzes the retro-aldol cleavage of 4-hydroxy-2- oxopentanoate to pyruvate and acetaldehyde. Is involved in the meta- cleavage pathway for the degradation of aromatic compounds. Belongs to the 4-hydroxy-2-oxovalerate aldolase family. (348 aa)
arsR-2ArsR-family transcriptional regulator. (109 aa)
linX2,5-dichloro-2,5-cyclohexadiene-1,4-diol dehydrogenase LinX; Catalyzes the degradation of 2,5-dichloro-2,5-cyclohexadiene- 1,4-diol (2,5-DDOL) into 2,5-dichlorohydroquinone (2,5-DCHQ) in vitro. LinX appears not to be involved in gamma-hexachlorocyclohexane (gamma- HCH) degradation pathway, in contrast to LinC which has the same enzymatic activity; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (250 aa)
tfdEDienelactone hydrolase. (248 aa)
lysCAspartate kinase; Belongs to the aspartokinase family. (421 aa)
luxR-4LuxR-family transcriptional regulator; DNA-binding HTH domain-containing protein. (248 aa)
linFMaleylacetate reductase LinF; Catalyzes the NADH-dependent reduction of maleylacetate to beta-ketoadipate, a step in the degradation of gamma- hexachlorocyclohexane (gamma-HCH or lindane). Has an essential role in this assimilation pathway that allows S.japonicum UT26 to grow on gamma-HCH as the sole source of carbon and energy. (352 aa)
linEb2,6-dichloro-p-hydroquinone 1,2-dioxygenase LinEb; Gamma-hexachlorocyclohexane degradation. (320 aa)
linJacetyl-CoA C-acetyltransferase LinJ; Gamma-hexachlorocyclohexane degradation; Belongs to the thiolase-like superfamily. Thiolase family. (403 aa)
linH3-oxoadipate CoA-succinyltransferase beta subunit LinH; Gamma-hexachlorocyclohexane degradation. (212 aa)
Your Current Organism:
Sphingobium japonicum
NCBI taxonomy Id: 452662
Other names: S. japonicum UT26S, Sphingobium japonicum UT26, Sphingobium japonicum UT26S, Sphingobium japonicum str. UT26S, Sphingobium japonicum strain UT26S
Server load: low (34%) [HD]