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A0A109UYE6 A0A109UYE6 HCR1 HCR1 A0A109UY01 A0A109UY01 A0A109UXI8 A0A109UXI8 A0A109UXB3 A0A109UXB3 A0A109UX73 A0A109UX73 A0A109UX69 A0A109UX69 A0A109UX45 A0A109UX45 A0A109UW69 A0A109UW69 A0A109UW52 A0A109UW52 AW171_hschr282 AW171_hschr282 A0A109UVY9 A0A109UVY9 A0A0X8HWU6 A0A0X8HWU6 A0A0X8HWU4 A0A0X8HWU4 A0A0X8HWN7 A0A0X8HWN7 A0A0X8HWL5 A0A0X8HWL5 A0A0X8HWA1 A0A0X8HWA1 TIF6 TIF6 A0A0X8HW27 A0A0X8HW27 A0A0X8HVY5 A0A0X8HVY5 A0A0X8HVI5 A0A0X8HVI5 A0A0X8HV77 A0A0X8HV77 A0A0X8HV42 A0A0X8HV42 A0A0X8HV40 A0A0X8HV40 A0A0X8HUZ0 A0A0X8HUZ0 A0A0X8HUP7 A0A0X8HUP7 TIF34 TIF34 TIF35 TIF35 A0A0X8HU22 A0A0X8HU22 A0A0X8HTW8 A0A0X8HTW8 A0A125RDZ8 A0A125RDZ8 A0A0X8HTC7 A0A0X8HTC7 A0A0X8HTA8 A0A0X8HTA8 A0A0X8HT36 A0A0X8HT36 A0A0X8HT29 A0A0X8HT29 A0A0X8HSZ7 A0A0X8HSZ7 PRT1 PRT1 A0A0X8HRV4 A0A0X8HRV4 A0A0X8HRP8 A0A0X8HRP8 MEF1 MEF1 A0A0X8HRD1 A0A0X8HRD1 A0A0X8HRC4 A0A0X8HRC4 A0A0X8HQZ8 A0A0X8HQZ8 A0A0X8HTD5 A0A0X8HTD5 A0A125RDY6 A0A125RDY6 A0A125RDX1 A0A125RDX1 A0A125RDV3 A0A125RDV3 A0A120K2Y6 A0A120K2Y6 A0A120K2X5 A0A120K2X5 A0A120K2S1 A0A120K2S1 A0A120K2K8 A0A120K2K8 A0A120K290 A0A120K290 A0A120K265 A0A120K265 A0A120K207 A0A120K207 A0A120K1G0 A0A120K1G0 A0A120K0Y2 A0A120K0Y2 NIP1 NIP1 A0A109UZQ0 A0A109UZQ0 A0A109UZD5 A0A109UZD5
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
Your Input:
A0A109UYE6HCL534Cp; Belongs to the DEAD box helicase family. (639 aa)
HCR1Eukaryotic translation initiation factor 3 subunit J; Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation. (265 aa)
A0A109UY01HBR306Cp; Belongs to the RNR ribonuclease family. (1212 aa)
A0A109UXI8HBR382Wp. (543 aa)
A0A109UXB3HBR355Wp. (302 aa)
A0A109UX73ATPase expression protein 1; Required for translation of the mitochondrial OLI1 transcript encoding subunit 9 of mitochondrial ATP synthase. Belongs to the AEP1 family. (504 aa)
A0A109UX69HBR295Wp. (1667 aa)
A0A109UX45HBR265Cp. (693 aa)
A0A109UW69Eukaryotic translation initiation factor 3 subunit A. (899 aa)
A0A109UW52HBL309Cp; Belongs to the eukaryotic initiation factor 4E family. (209 aa)
AW171_hschr282Cap-associated protein CAF20; Acts as an inhibitor of cap-dependent translation. Competes with eIF4G1 and EAP1 for binding to eIF4E and interferes with the formation of the eIF4F complex, inhibiting translation and stabilizing mRNA; Belongs to the CAF20 family. (147 aa)
A0A109UVY9HCL585Cp. (162 aa)
A0A0X8HWU6HHR111Cp. (178 aa)
A0A0X8HWU4HHR210Cp. (731 aa)
A0A0X8HWN7Elongation factor Tu; This protein promotes the GTP-dependent binding of aminoacyl- tRNA to the A-site of ribosomes during protein biosynthesis. (432 aa)
A0A0X8HWL5HHR090Cp. (437 aa)
A0A0X8HWA1HHL187Cp; Belongs to the GST superfamily. (228 aa)
TIF6Eukaryotic translation initiation factor 6; Binds to the 60S ribosomal subunit and prevents its association with the 40S ribosomal subunit to form the 80S initiation complex in the cytoplasm. Is also involved in ribosome biogenesis. Associates with pre-60S subunits in the nucleus and is involved in its nuclear export; Belongs to the eIF-6 family. (245 aa)
A0A0X8HW27HHL206Wp. (480 aa)
A0A0X8HVY5HGR061Cp; Seems to be required for maximal rate of protein biosynthesis. Enhances ribosome dissociation into subunits and stabilizes the binding of the initiator Met-tRNA(I) to 40 S ribosomal subunits. (155 aa)
A0A0X8HVI5HHL274Cp; Belongs to the DEAD box helicase family. (396 aa)
A0A0X8HV77HGL327Cp. (842 aa)
A0A0X8HV42HGL039Wp. (1027 aa)
A0A0X8HV40HGL295Wp. (429 aa)
A0A0X8HUZ0HGL114Cp. (280 aa)
A0A0X8HUP7Eukaryotic translation initiation factor 2A; Functions in the early steps of protein synthesis of a small number of specific mRNAs. Acts by directing the binding of methionyl- tRNAi to 40S ribosomal subunits. In contrast to the eIF-2 complex, it binds methionyl-tRNAi to 40S subunits in a codon-dependent manner, whereas the eIF-2 complex binds methionyl-tRNAi to 40S subunits in a GTP-dependent manner. (634 aa)
TIF34Eukaryotic translation initiation factor 3 subunit I; Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation. (347 aa)
TIF35Eukaryotic translation initiation factor 3 subunit G; RNA-binding component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation. This subunit can bind 18S rRNA. (271 aa)
A0A0X8HU22HER134Cp. (282 aa)
A0A0X8HTW8HER121Cp. (1177 aa)
A0A125RDZ8HBR114Wp. (682 aa)
A0A0X8HTC7HEL228Wp. (822 aa)
A0A0X8HTA8HEL217Wp. (974 aa)
A0A0X8HT36HDR161Wp. (859 aa)
A0A0X8HT29HEL329Cp. (659 aa)
A0A0X8HSZ7HDR159Cp. (414 aa)
PRT1Eukaryotic translation initiation factor 3 subunit B; Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome; Belongs to the eIF-3 subunit B family. (732 aa)
A0A0X8HRV4HDL424Cp. (186 aa)
A0A0X8HRP8HDL545Wp. (931 aa)
MEF1Elongation factor G, mitochondrial; Mitochondrial GTPase that catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome. (759 aa)
A0A0X8HRD1HCL112Cp. (1044 aa)
A0A0X8HRC4HCL132Wp. (670 aa)
A0A0X8HQZ8HDL363Wp. (518 aa)
A0A0X8HTD5HEL182Cp. (500 aa)
A0A125RDY6HBR024Cp. (560 aa)
A0A125RDX1HBL086Cp; Belongs to the eIF-2B alpha/beta/delta subunits family. (608 aa)
A0A125RDV3Translation machinery-associated protein 22. (203 aa)
A0A120K2Y6HHR226Wp. (407 aa)
A0A120K2X5HHR122Cp; Belongs to the eIF-2B alpha/beta/delta subunits family. (375 aa)
A0A120K2S1HGR057Cp. (802 aa)
A0A120K2K8HFR003Cp; Belongs to the EF-1-beta/EF-1-delta family. (204 aa)
A0A120K290HDR032Cp. (776 aa)
A0A120K265HDL192Wp. (515 aa)
A0A120K207HCL095Wp. (397 aa)
A0A120K1G0HBR448Wp; Belongs to the eIF-2B alpha/beta/delta subunits family. (304 aa)
A0A120K0Y2Elongation factor 1-alpha; This protein promotes the GTP-dependent binding of aminoacyl- tRNA to the A-site of ribosomes during protein biosynthesis. (458 aa)
NIP1Eukaryotic translation initiation factor 3 subunit C; Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation. (814 aa)
A0A109UZQ0Eukaryotic translation initiation factor 5A. (157 aa)
A0A109UZD5HCL579Wp. (108 aa)
Your Current Organism:
Eremothecium sinecaudum
NCBI taxonomy Id: 45286
Other names: ATCC 58844, CBS 8199, CCRC 21344, CCRC:21344, DAOM 187446, E. sinecaudum, Eremothecium sinecaudum (Holley) Kurtzman, Holleya sinecauda, NRRL Y-17231, Nematospora sinecauda
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