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A0A0E0N0U7 | Origin of replication complex subunit 4; Component of the origin recognition complex (ORC) that binds origins of replication; Belongs to the ORC4 family. (381 aa) | ||||
A0A0E0MXR8 | DNA helicase; Belongs to the MCM family. (853 aa) | ||||
A0A0E0MTW9 | DNA replication complex GINS protein PSF2; Belongs to the GINS2/PSF2 family. (228 aa) | ||||
A0A0E0MSC8 | FACT complex subunit SSRP1; Component of the FACT complex, a general chromatin factor that acts to reorganize nucleosomes. The FACT complex is involved in multiple processes that require DNA as a template such as mRNA elongation, DNA replication and DNA repair. During transcription elongation the FACT complex acts as a histone chaperone that both destabilizes and restores nucleosomal structure. It facilitates the passage of RNA polymerase II and transcription by promoting the dissociation of one histone H2A-H2B dimer from the nucleosome, then subsequently promotes the reestablishment o [...] (684 aa) | ||||
MCM7 | DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...] (715 aa) | ||||
A0A0E0PHC8 | DNA replication complex GINS protein SLD5; The GINS complex plays an essential role in the initiation of DNA replication; Belongs to the GINS4/SLD5 family. (228 aa) | ||||
A0A0E0PHW3 | DNA polymerase epsilon subunit; Participates in DNA repair and in chromosomal DNA replication; Belongs to the DNA polymerase epsilon subunit B family. (500 aa) | ||||
A0A0E0PIC5 | FACT complex subunit SSRP1; Component of the FACT complex, a general chromatin factor that acts to reorganize nucleosomes. The FACT complex is involved in multiple processes that require DNA as a template such as mRNA elongation, DNA replication and DNA repair. During transcription elongation the FACT complex acts as a histone chaperone that both destabilizes and restores nucleosomal structure. It facilitates the passage of RNA polymerase II and transcription by promoting the dissociation of one histone H2A-H2B dimer from the nucleosome, then subsequently promotes the reestablishment o [...] (640 aa) | ||||
A0A0E0PJC1 | DNA helicase; Belongs to the MCM family. (814 aa) | ||||
A0A0E0PLB1 | DNA primase; Belongs to the eukaryotic-type primase small subunit family. (426 aa) | ||||
A0A0E0PND8 | Sld5 domain-containing protein. (210 aa) | ||||
A0A0E0PNX3 | DNA helicase; Belongs to the MCM family. (770 aa) | ||||
A0A0E0PU14 | Ribonucleoside-diphosphate reductase; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. (865 aa) | ||||
A0A0E0PUF9 | Origin recognition complex subunit 1; Component of the origin recognition complex (ORC) that binds origins of replication. DNA-binding is ATP-dependent, however specific DNA sequences that define origins of replication have not been identified so far. ORC is required to assemble the pre-replication complex necessary to initiate DNA replication. (1164 aa) | ||||
A0A0E0QGN2 | Sld5 domain-containing protein. (194 aa) | ||||
A0A0E0QK27 | DNA polymerase epsilon subunit; Participates in DNA repair and in chromosomal DNA replication; Belongs to the DNA polymerase epsilon subunit B family. (492 aa) | ||||
A0A0E0R0P3 | DNA ligase. (912 aa) | ||||
A0A0E0R531 | DNA polymerase. (1082 aa) | ||||
A0A0E0R8F7 | DNA helicase; Belongs to the MCM family. (1258 aa) | ||||
A0A0E0R9X8 | Replication factor C subunit 1. (987 aa) | ||||
A0A0E0RFH5 | DNA polymerase alpha subunit B; Accessory subunit of the DNA polymerase alpha complex (also known as the alpha DNA polymerase-primase complex) which plays an essential role in the initiation of DNA synthesis. (576 aa) | ||||
A0A0E0NRJ4 | Replication protein A subunit; Component of the replication protein A complex (RPA) required for DNA recombination, repair and replication. The activity of RPA is mediated by single-stranded DNA binding and protein interactions. Probably involved in repair of double-strand DNA breaks (DSBs) induced by genotoxic stresses. (630 aa) | ||||
A0A0E0NMF4 | Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family. (263 aa) | ||||
A0A0E0NME6 | Ribonucleoside-diphosphate reductase; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. (810 aa) | ||||
A0A0E0NM64 | DNA helicase; Belongs to the MCM family. (698 aa) | ||||
A0A0E0NLM8 | Replication protein A subunit; Component of the replication protein A complex (RPA) required for DNA recombination, repair and replication. The activity of RPA is mediated by single-stranded DNA binding and protein interactions. Probably involved in repair of double-strand DNA breaks (DSBs) induced by genotoxic stresses. (656 aa) | ||||
A0A0E0NFE0 | DNA polymerase epsilon catalytic subunit; DNA polymerase II participates in chromosomal DNA replication; Belongs to the DNA polymerase type-B family. (2143 aa) | ||||
A0A0E0N5K1 | DNA polymerase. (1506 aa) |