(16 nodes) Clathrin-dependent endocytosis, and Coatomer/calthrin adaptor appendage, C-terminal subdomain network (Nematostella vectensis)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	v1g236331	AP-2 complex subunit alpha; Adaptins are components of the adaptor complexes which link clathrin to receptors in coated vesicles. Clathrin-associated protein complexes are believed to interact with the cytoplasmic tails of membrane proteins, leading to their selection and concentration. (943 aa)
	v1g239437	Predicted protein. (870 aa)
	v1g87337	Predicted protein. (60 aa)
	v1g94203	Predicted protein. (370 aa)
	v1g202524	Predicted protein. (357 aa)
	v1g94407	Predicted protein. (127 aa)
	v1g94465	Predicted protein. (127 aa)
	v1g241115	Predicted protein. (1408 aa)
	v1g101531	AP complex subunit sigma; Belongs to the adaptor complexes small subunit family. (142 aa)
	v1g102934	Predicted protein; Belongs to the adaptor complexes medium subunit family. (429 aa)
	v1g106806	Predicted protein. (254 aa)
	v1g171064	Predicted protein. (270 aa)
	v1g12640	Predicted protein. (261 aa)
	v1g190491	AP complex subunit beta. (882 aa)
	v1g246997	Predicted protein. (610 aa)
	v1g143432	Predicted protein. (294 aa)

Your Current Organism:

Nematostella vectensis

NCBI taxonomy Id: 45351
Other names: N. vectensis, starlet sea anemone

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
v1g101531	v1g102934	A7S269	A7S370	AP complex subunit sigma; Belongs to the adaptor complexes small subunit family.	Predicted protein; Belongs to the adaptor complexes medium subunit family.	0.999
v1g101531	v1g106806	A7S269	A7S6P0	AP complex subunit sigma; Belongs to the adaptor complexes small subunit family.	Predicted protein.	0.860
v1g101531	v1g12640	A7S269	A7SJ57	AP complex subunit sigma; Belongs to the adaptor complexes small subunit family.	Predicted protein.	0.860
v1g101531	v1g143432	A7S269	A7T2S0	AP complex subunit sigma; Belongs to the adaptor complexes small subunit family.	Predicted protein.	0.982
v1g101531	v1g171064	A7S269	A7SIZ0	AP complex subunit sigma; Belongs to the adaptor complexes small subunit family.	Predicted protein.	0.925
v1g101531	v1g190491	A7S269	A7SJK8	AP complex subunit sigma; Belongs to the adaptor complexes small subunit family.	AP complex subunit beta.	0.994
v1g101531	v1g202524	A7S269	A7RUY7	AP complex subunit sigma; Belongs to the adaptor complexes small subunit family.	Predicted protein.	0.982
v1g101531	v1g236331	A7S269	A7RH33	AP complex subunit sigma; Belongs to the adaptor complexes small subunit family.	AP-2 complex subunit alpha; Adaptins are components of the adaptor complexes which link clathrin to receptors in coated vesicles. Clathrin-associated protein complexes are believed to interact with the cytoplasmic tails of membrane proteins, leading to their selection and concentration.	0.998
v1g101531	v1g239437	A7S269	A7RMS3	AP complex subunit sigma; Belongs to the adaptor complexes small subunit family.	Predicted protein.	0.992
v1g101531	v1g241115	A7S269	A7RW68	AP complex subunit sigma; Belongs to the adaptor complexes small subunit family.	Predicted protein.	0.774
v1g101531	v1g246997	A7S269	A7SRT4	AP complex subunit sigma; Belongs to the adaptor complexes small subunit family.	Predicted protein.	0.661
v1g101531	v1g87337	A7S269	A7RMS4	AP complex subunit sigma; Belongs to the adaptor complexes small subunit family.	Predicted protein.	0.982
v1g101531	v1g94203	A7S269	A7RUX4	AP complex subunit sigma; Belongs to the adaptor complexes small subunit family.	Predicted protein.	0.831
v1g101531	v1g94407	A7S269	A7RUZ2	AP complex subunit sigma; Belongs to the adaptor complexes small subunit family.	Predicted protein.	0.992
v1g101531	v1g94465	A7S269	A7RUZ5	AP complex subunit sigma; Belongs to the adaptor complexes small subunit family.	Predicted protein.	0.992
v1g102934	v1g101531	A7S370	A7S269	Predicted protein; Belongs to the adaptor complexes medium subunit family.	AP complex subunit sigma; Belongs to the adaptor complexes small subunit family.	0.999
v1g102934	v1g106806	A7S370	A7S6P0	Predicted protein; Belongs to the adaptor complexes medium subunit family.	Predicted protein.	0.846
v1g102934	v1g12640	A7S370	A7SJ57	Predicted protein; Belongs to the adaptor complexes medium subunit family.	Predicted protein.	0.846
v1g102934	v1g143432	A7S370	A7T2S0	Predicted protein; Belongs to the adaptor complexes medium subunit family.	Predicted protein.	0.989
v1g102934	v1g171064	A7S370	A7SIZ0	Predicted protein; Belongs to the adaptor complexes medium subunit family.	Predicted protein.	0.988