(14 nodes) Retromer complex, and Sorting nexin/Vps5-like, C-terminal network (Nematostella vectensis)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	v1g176880	Predicted protein. (522 aa)
	v1g85927	Predicted protein. (418 aa)
	v1g87802	Predicted protein. (363 aa)
	v1g161158	Sorting nexin; Involved in several stages of intracellular trafficking. (391 aa)
	v1g161846	Vacuolar protein sorting-associated protein 35; Plays a role in vesicular protein sorting. (768 aa)
	v1g182326	Vacuolar protein sorting-associated protein 29; Acts as component of the retromer cargo-selective complex (CSC). The CSC is believed to be the core functional component of retromer or respective retromer complex variants acting to prevent missorting of selected transmembrane cargo proteins into the lysosomal degradation pathway. (182 aa)
	v1g100430	Predicted protein. (502 aa)
	v1g229200	Predicted protein. (311 aa)
	v1g244464	Predicted protein. (168 aa)
	v1g244990	Predicted protein. (327 aa)
	v1g246794	Predicted protein. (428 aa)
	v1g247042	Predicted protein. (426 aa)
	v1g134716	Predicted protein. (391 aa)
	v1g146526	Predicted protein. (193 aa)

Your Current Organism:

Nematostella vectensis

NCBI taxonomy Id: 45351
Other names: N. vectensis, starlet sea anemone

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
v1g100430	v1g134716	A7S129	A7SW17	Predicted protein.	Predicted protein.	0.429
v1g100430	v1g146526	A7S129	A7T5B7	Predicted protein.	Predicted protein.	0.766
v1g100430	v1g161846	A7S129	A7RRD4	Predicted protein.	Vacuolar protein sorting-associated protein 35; Plays a role in vesicular protein sorting.	0.766
v1g100430	v1g182326	A7S129	A7RV73	Predicted protein.	Vacuolar protein sorting-associated protein 29; Acts as component of the retromer cargo-selective complex (CSC). The CSC is believed to be the core functional component of retromer or respective retromer complex variants acting to prevent missorting of selected transmembrane cargo proteins into the lysosomal degradation pathway.	0.850
v1g100430	v1g229200	A7S129	A7S1T2	Predicted protein.	Predicted protein.	0.770
v1g100430	v1g244464	A7S129	A7SD93	Predicted protein.	Predicted protein.	0.858
v1g100430	v1g244990	A7S129	A7SFV3	Predicted protein.	Predicted protein.	0.591
v1g134716	v1g100430	A7SW17	A7S129	Predicted protein.	Predicted protein.	0.429
v1g134716	v1g146526	A7SW17	A7T5B7	Predicted protein.	Predicted protein.	0.967
v1g134716	v1g161158	A7SW17	A7RP73	Predicted protein.	Sorting nexin; Involved in several stages of intracellular trafficking.	0.988
v1g134716	v1g161846	A7SW17	A7RRD4	Predicted protein.	Vacuolar protein sorting-associated protein 35; Plays a role in vesicular protein sorting.	0.967
v1g134716	v1g176880	A7SW17	A7REN9	Predicted protein.	Predicted protein.	0.754
v1g134716	v1g182326	A7SW17	A7RV73	Predicted protein.	Vacuolar protein sorting-associated protein 29; Acts as component of the retromer cargo-selective complex (CSC). The CSC is believed to be the core functional component of retromer or respective retromer complex variants acting to prevent missorting of selected transmembrane cargo proteins into the lysosomal degradation pathway.	0.989
v1g134716	v1g229200	A7SW17	A7S1T2	Predicted protein.	Predicted protein.	0.990
v1g134716	v1g244464	A7SW17	A7SD93	Predicted protein.	Predicted protein.	0.812
v1g134716	v1g244990	A7SW17	A7SFV3	Predicted protein.	Predicted protein.	0.467
v1g134716	v1g246794	A7SW17	A7SQP0	Predicted protein.	Predicted protein.	0.729
v1g134716	v1g247042	A7SW17	A7SS20	Predicted protein.	Predicted protein.	0.661
v1g134716	v1g85927	A7SW17	A7RLS4	Predicted protein.	Predicted protein.	0.719
v1g134716	v1g87802	A7SW17	A7RNQ3	Predicted protein.	Predicted protein.	0.638