(5 nodes) MAP kinase kinase kinase kinase activity, and Domain found in NIK1-like kinases, mouse citron and yeast ROM1, ROM2 network (Nematostella vectensis)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	v1g81874	Predicted protein. (354 aa)
	v1g158852	Predicted protein; Belongs to the protein kinase superfamily. (310 aa)
	v1g85505	Predicted protein; Belongs to the protein kinase superfamily. (273 aa)
	v1g105673	Predicted protein. (328 aa)
	v1g105663	Predicted protein; Belongs to the protein kinase superfamily. (314 aa)

Your Current Organism:

Nematostella vectensis

NCBI taxonomy Id: 45351
Other names: N. vectensis, starlet sea anemone

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
v1g105663	v1g105673	A7S5T6	A7S5T5	Predicted protein; Belongs to the protein kinase superfamily.	Predicted protein.	0.632
v1g105663	v1g81874	A7S5T6	A7RHW0	Predicted protein; Belongs to the protein kinase superfamily.	Predicted protein.	0.870
v1g105673	v1g105663	A7S5T5	A7S5T6	Predicted protein.	Predicted protein; Belongs to the protein kinase superfamily.	0.632
v1g105673	v1g158852	A7S5T5	A7RHW1	Predicted protein.	Predicted protein; Belongs to the protein kinase superfamily.	0.895
v1g105673	v1g85505	A7S5T5	A7RL88	Predicted protein.	Predicted protein; Belongs to the protein kinase superfamily.	0.870
v1g158852	v1g105673	A7RHW1	A7S5T5	Predicted protein; Belongs to the protein kinase superfamily.	Predicted protein.	0.895
v1g158852	v1g81874	A7RHW1	A7RHW0	Predicted protein; Belongs to the protein kinase superfamily.	Predicted protein.	0.422
v1g81874	v1g105663	A7RHW0	A7S5T6	Predicted protein.	Predicted protein; Belongs to the protein kinase superfamily.	0.870
v1g81874	v1g158852	A7RHW0	A7RHW1	Predicted protein.	Predicted protein; Belongs to the protein kinase superfamily.	0.422
v1g81874	v1g85505	A7RHW0	A7RL88	Predicted protein.	Predicted protein; Belongs to the protein kinase superfamily.	0.643
v1g85505	v1g105673	A7RL88	A7S5T5	Predicted protein; Belongs to the protein kinase superfamily.	Predicted protein.	0.870
v1g85505	v1g81874	A7RL88	A7RHW0	Predicted protein; Belongs to the protein kinase superfamily.	Predicted protein.	0.643