STRINGSTRING
v1g79311 v1g79311 v1g237900 v1g237900 v1g238046 v1g238046 v1g158364 v1g158364 v1g39202 v1g39202 v1g82359 v1g82359 v1g236362 v1g236362 v1g197727 v1g197727 v1g239675 v1g239675 v1g200367 v1g200367 v1g89666 v1g89666 FEN1 FEN1 v1g94785 v1g94785 v1g163148 v1g163148 v1g94752 v1g94752 v1g182679 v1g182679 v1g95776 v1g95776 v1g95659 v1g95659 v1g95716 v1g95716 v1g97672 v1g97672 v1g205056 v1g205056 v1g102593 v1g102593 v1g102735 v1g102735 v1g242707 v1g242707 v1g206509 v1g206509 v1g103926 v1g103926 v1g104131 v1g104131 v1g166542 v1g166542 v1g166761 v1g166761 v1g166966 v1g166966 v1g208115 v1g208115 v1g108642 v1g108642 v1g208764 v1g208764 v1g209079 v1g209079 v1g209082 v1g209082 v1g168196 v1g168196 v1g209438 v1g209438 v1g209585 v1g209585 v1g112203 v1g112203 v1g188209 v1g188209 v1g113922 v1g113922 v1g210850 v1g210850 v1g244659 v1g244659 v1g211009 v1g211009 v1g18425 v1g18425 v1g119262 v1g119262 v1g171012 v1g171012 v1g245550 v1g245550 v1g171280 v1g171280 v1g121396 v1g121396 v1g121468 v1g121468 v1g246110 v1g246110 v1g123738 v1g123738 v1g11039 v1g11039 v1g125757 v1g125757 v1g127336 v1g127336 v1g246872 v1g246872 v1g129738 v1g129738 v1g130169 v1g130169 v1g130162 v1g130162 v1g130385 v1g130385 v1g193548 v1g193548 v1g132328 v1g132328 v1g218321 v1g218321 v1g247824 v1g247824 v1g247825 v1g247825 v1g137694 v1g137694 v1g138657 v1g138657 v1g139755 v1g139755 v1g7216 v1g7216 v1g5939 v1g5939 v1g145330 v1g145330 v1g146476 v1g146476 v1g222712 v1g222712 v1g222714 v1g222714 v1g222786 v1g222786 v1g223444 v1g223444 v1g224077 v1g224077 v1g152036 v1g152036 v1g224415 v1g224415 v1g8766 v1g8766 v1g150968 v1g150968 v1g225594 v1g225594 v1g156451 v1g156451 v1g225758 v1g225758 v1g225933 v1g225933
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
v1g79311Predicted protein. (198 aa)
v1g237900Predicted protein. (530 aa)
v1g238046Predicted protein. (1837 aa)
v1g158364Checkpoint protein; Belongs to the HUS1 family. (281 aa)
v1g39202Predicted protein. (88 aa)
v1g82359Predicted protein. (120 aa)
v1g236362Predicted protein. (114 aa)
v1g197727Predicted protein. (381 aa)
v1g239675Predicted protein. (757 aa)
v1g200367Predicted protein. (556 aa)
v1g89666Predicted protein. (140 aa)
FEN1Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...] (377 aa)
v1g94785Predicted protein. (314 aa)
v1g163148Predicted protein. (518 aa)
v1g94752Predicted protein. (124 aa)
v1g182679DNA topoisomerase; Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. Belongs to the type IA topoisomerase family. (856 aa)
v1g95776Predicted protein. (134 aa)
v1g95659Predicted protein. (292 aa)
v1g95716Predicted protein. (219 aa)
v1g97672Predicted protein. (204 aa)
v1g205056Predicted protein. (657 aa)
v1g102593Predicted protein. (168 aa)
v1g102735Predicted protein. (119 aa)
v1g242707Predicted protein. (794 aa)
v1g206509Predicted protein. (132 aa)
v1g103926Predicted protein; Belongs to the PI3/PI4-kinase family. (70 aa)
v1g104131Predicted protein. (199 aa)
v1g166542Predicted protein. (329 aa)
v1g166761Predicted protein. (357 aa)
v1g166966Predicted protein. (355 aa)
v1g208115Predicted protein. (238 aa)
v1g108642DNA topoisomerase; Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. Belongs to the type IA topoisomerase family. (940 aa)
v1g208764Predicted protein. (446 aa)
v1g209079Predicted protein. (108 aa)
v1g209082Predicted protein. (401 aa)
v1g168196Regulator of telomere elongation helicase 1 homolog; ATP-dependent DNA helicase implicated in DNA repair and the maintenance of genomic stability. Acts as an anti-recombinase to counteract toxic recombination and limit crossover during meiosis. Regulates meiotic recombination and crossover homeostasis by physically dissociating strand invasion events and thereby promotes noncrossover repair by meiotic synthesis dependent strand annealing (SDSA) as well as disassembly of D loop recombination intermediates. (1082 aa)
v1g209438Predicted protein. (576 aa)
v1g209585Predicted protein. (150 aa)
v1g112203Predicted protein. (1428 aa)
v1g188209DNA ligase. (609 aa)
v1g113922Predicted protein. (264 aa)
v1g210850Predicted protein. (866 aa)
v1g244659Predicted protein. (2095 aa)
v1g211009Predicted protein. (169 aa)
v1g18425Predicted protein. (64 aa)
v1g119262Predicted protein. (90 aa)
v1g171012Predicted protein; Belongs to the PI3/PI4-kinase family. (1722 aa)
v1g245550Double-strand break repair protein; Involved in DNA double-strand break repair (DSBR). Possesses single-strand endonuclease activity and double-strand-specific 3'-5' exonuclease activity. Also involved in meiotic DSB processing. (720 aa)
v1g171280Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage. (626 aa)
v1g121396Predicted protein. (237 aa)
v1g121468Predicted protein. (237 aa)
v1g246110Predicted protein. (1820 aa)
v1g123738Predicted protein. (76 aa)
v1g11039Predicted protein. (491 aa)
v1g125757Predicted protein. (513 aa)
v1g127336ATP-dependent DNA helicase; Belongs to the helicase family. RecQ subfamily. (424 aa)
v1g246872Predicted protein. (1520 aa)
v1g129738Predicted protein. (53 aa)
v1g130169Predicted protein. (181 aa)
v1g130162Predicted protein. (158 aa)
v1g130385Predicted protein. (91 aa)
v1g193548Predicted protein. (286 aa)
v1g132328Predicted protein. (793 aa)
v1g218321Predicted protein. (128 aa)
v1g247824Predicted protein. (560 aa)
v1g247825Predicted protein. (633 aa)
v1g137694Predicted protein. (95 aa)
v1g138657Predicted protein. (124 aa)
v1g139755Predicted protein; Belongs to the protein kinase superfamily. (474 aa)
v1g7216Predicted protein. (79 aa)
v1g5939Predicted protein. (127 aa)
v1g145330Predicted protein; Belongs to the PI3/PI4-kinase family. (213 aa)
v1g146476Predicted protein. (88 aa)
v1g222712DNA topoisomerase; Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. Belongs to the type IA topoisomerase family. (231 aa)
v1g222714Predicted protein. (442 aa)
v1g222786Predicted protein. (274 aa)
v1g223444Predicted protein. (107 aa)
v1g224077Predicted protein. (161 aa)
v1g152036Predicted protein. (61 aa)
v1g224415Predicted protein. (103 aa)
v1g8766Predicted protein. (111 aa)
v1g150968Predicted protein; Belongs to the PI3/PI4-kinase family. (70 aa)
v1g225594Predicted protein. (109 aa)
v1g156451Predicted protein. (101 aa)
v1g225758Predicted protein. (115 aa)
v1g225933Predicted protein. (371 aa)
Your Current Organism:
Nematostella vectensis
NCBI taxonomy Id: 45351
Other names: N. vectensis, starlet sea anemone
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