(16 nodes) Heparan sulfate proteoglycan biosynthetic process network (Nematostella vectensis)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	v1g85640	Predicted protein. (518 aa)
	v1g191320	UDP-glucose 6-dehydrogenase; Involved in the biosynthesis of glycosaminoglycans; hyaluronan, chondroitin sulfate, and heparan sulfate. Belongs to the UDP-glucose/GDP-mannose dehydrogenase family. (480 aa)
	v1g237290	Heparan-sulfate 6-O-sulfotransferase; 6-O-sulfation enzyme which catalyzes the transfer of sulfate from 3'-phosphoadenosine 5'-phosphosulfate (PAPS) to position 6 of the N-sulfoglucosamine residue (GlcNS) of heparan sulfate. (374 aa)
	v1g118618	Predicted protein. (715 aa)
	v1g168451	Predicted protein; Belongs to the glycosyltransferase 47 family. (563 aa)
	v1g247365	Predicted protein. (893 aa)
	v1g131441	Predicted protein. (92 aa)
	v1g175792	Hexosyltransferase. (287 aa)
	v1g1205	Predicted protein. (261 aa)
	v1g149898	Predicted protein. (299 aa)
	v1g154825	Predicted protein. (106 aa)
	v1g155187	Predicted protein. (151 aa)
	v1g235881	Predicted protein; Belongs to the glycosyltransferase 47 family. (881 aa)
	v1g173450	Predicted protein; Belongs to the glycosyltransferase 47 family. (728 aa)
	v1g127675	Predicted protein. (266 aa)
	v1g98166	Predicted protein. (276 aa)

Your Current Organism:

Nematostella vectensis

NCBI taxonomy Id: 45351
Other names: N. vectensis, starlet sea anemone

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
v1g118618	v1g175792	A7SHI4	A7SZM8	Predicted protein.	Hexosyltransferase.	0.678
v1g118618	v1g235881	A7SHI4	A7SS73	Predicted protein.	Predicted protein; Belongs to the glycosyltransferase 47 family.	0.638
v1g118618	v1g237290	A7SHI4	A7SIL9	Predicted protein.	Heparan-sulfate 6-O-sulfotransferase; 6-O-sulfation enzyme which catalyzes the transfer of sulfate from 3'-phosphoadenosine 5'-phosphosulfate (PAPS) to position 6 of the N-sulfoglucosamine residue (GlcNS) of heparan sulfate.	0.431
v1g118618	v1g85640	A7SHI4	A7RL51	Predicted protein.	Predicted protein.	0.639
v1g118618	v1g98166	A7SHI4	A7RYU9	Predicted protein.	Predicted protein.	0.642
v1g1205	v1g149898	A7T0E6	A7T895	Predicted protein.	Predicted protein.	0.900
v1g127675	v1g149898	A7SQL8	A7T895	Predicted protein.	Predicted protein.	0.900
v1g149898	v1g1205	A7T895	A7T0E6	Predicted protein.	Predicted protein.	0.900
v1g149898	v1g127675	A7T895	A7SQL8	Predicted protein.	Predicted protein.	0.900
v1g154825	v1g173450	A7TCH8	A7SR92	Predicted protein.	Predicted protein; Belongs to the glycosyltransferase 47 family.	0.946
v1g154825	v1g98166	A7TCH8	A7RYU9	Predicted protein.	Predicted protein.	0.471
v1g168451	v1g173450	A7SAR9	A7SR92	Predicted protein; Belongs to the glycosyltransferase 47 family.	Predicted protein; Belongs to the glycosyltransferase 47 family.	0.994
v1g168451	v1g98166	A7SAR9	A7RYU9	Predicted protein; Belongs to the glycosyltransferase 47 family.	Predicted protein.	0.471
v1g173450	v1g154825	A7SR92	A7TCH8	Predicted protein; Belongs to the glycosyltransferase 47 family.	Predicted protein.	0.946
v1g173450	v1g168451	A7SR92	A7SAR9	Predicted protein; Belongs to the glycosyltransferase 47 family.	Predicted protein; Belongs to the glycosyltransferase 47 family.	0.994
v1g173450	v1g237290	A7SR92	A7SIL9	Predicted protein; Belongs to the glycosyltransferase 47 family.	Heparan-sulfate 6-O-sulfotransferase; 6-O-sulfation enzyme which catalyzes the transfer of sulfate from 3'-phosphoadenosine 5'-phosphosulfate (PAPS) to position 6 of the N-sulfoglucosamine residue (GlcNS) of heparan sulfate.	0.639
v1g173450	v1g85640	A7SR92	A7RL51	Predicted protein; Belongs to the glycosyltransferase 47 family.	Predicted protein.	0.639
v1g173450	v1g98166	A7SR92	A7RYU9	Predicted protein; Belongs to the glycosyltransferase 47 family.	Predicted protein.	0.655
v1g175792	v1g118618	A7SZM8	A7SHI4	Hexosyltransferase.	Predicted protein.	0.678
v1g175792	v1g235881	A7SZM8	A7SS73	Hexosyltransferase.	Predicted protein; Belongs to the glycosyltransferase 47 family.	0.434