(16 nodes) Cytokine binding network (Nematostella vectensis)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	v1g200866	Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (299 aa)
	v1g118140	Predicted protein. (112 aa)
	v1g15221	Predicted protein. (112 aa)
	v1g39945	Predicted protein. (55 aa)
	v1g196912	Predicted protein. (225 aa)
	v1g40721	Predicted protein. (322 aa)
	v1g211528	Predicted protein; Belongs to the G-protein coupled receptor 1 family. (331 aa)
	v1g211454	Predicted protein. (189 aa)
	v1g104199	Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (387 aa)
	v1g242758	Predicted protein. (856 aa)
	v1g206573	Predicted protein; Belongs to the G-protein coupled receptor 1 family. (344 aa)
	v1g100552	Predicted protein. (228 aa)
	v1g99718	Predicted protein; Belongs to the G-protein coupled receptor 1 family. (293 aa)
	v1g203940	Predicted protein. (225 aa)
	v1g203613	Predicted protein. (393 aa)
	v1g95464	Predicted protein. (98 aa)

Your Current Organism:

Nematostella vectensis

NCBI taxonomy Id: 45351
Other names: N. vectensis, starlet sea anemone

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
v1g100552	v1g242758	A7S140	A7S4A8	Predicted protein.	Predicted protein.	0.755
v1g104199	v1g242758	A7S4E9	A7S4A8	Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.	Predicted protein.	0.446
v1g118140	v1g15221	A7SH36	A7SH37	Predicted protein.	Predicted protein.	0.910
v1g118140	v1g242758	A7SH36	A7S4A8	Predicted protein.	Predicted protein.	0.819
v1g118140	v1g95464	A7SH36	A7RW37	Predicted protein.	Predicted protein.	0.586
v1g15221	v1g118140	A7SH37	A7SH36	Predicted protein.	Predicted protein.	0.910
v1g15221	v1g242758	A7SH37	A7S4A8	Predicted protein.	Predicted protein.	0.606
v1g15221	v1g95464	A7SH37	A7RW37	Predicted protein.	Predicted protein.	0.586
v1g200866	v1g242758	A7RR38	A7S4A8	Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.	Predicted protein.	0.446
v1g211454	v1g95464	A7SFF6	A7RW37	Predicted protein.	Predicted protein.	0.418
v1g242758	v1g100552	A7S4A8	A7S140	Predicted protein.	Predicted protein.	0.755
v1g242758	v1g104199	A7S4A8	A7S4E9	Predicted protein.	Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.	0.446
v1g242758	v1g118140	A7S4A8	A7SH36	Predicted protein.	Predicted protein.	0.819
v1g242758	v1g15221	A7S4A8	A7SH37	Predicted protein.	Predicted protein.	0.606
v1g242758	v1g200866	A7S4A8	A7RR38	Predicted protein.	Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.	0.446
v1g242758	v1g95464	A7S4A8	A7RW37	Predicted protein.	Predicted protein.	0.636
v1g95464	v1g118140	A7RW37	A7SH36	Predicted protein.	Predicted protein.	0.586
v1g95464	v1g15221	A7RW37	A7SH37	Predicted protein.	Predicted protein.	0.586
v1g95464	v1g211454	A7RW37	A7SFF6	Predicted protein.	Predicted protein.	0.418
v1g95464	v1g242758	A7RW37	A7S4A8	Predicted protein.	Predicted protein.	0.636