(8 nodes) HOPS complex network (Nematostella vectensis)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	v1g228040	Vacuolar protein sorting-associated protein 16 homolog; Plays a role in vesicle-mediated protein trafficking to lysosomal compartments including the endocytic membrane transport and autophagic pathways. Believed to act as a core component of the putative HOPS and CORVET endosomal tethering complexes. Belongs to the VPS16 family. (770 aa)
	v1g85536	Predicted protein. (940 aa)
	v1g95934	Predicted protein; Belongs to the STXBP/unc-18/SEC1 family. (589 aa)
	v1g96025	Predicted protein; Belongs to the STXBP/unc-18/SEC1 family. (547 aa)
	v1g184544	Vacuolar protein sorting-associated protein 41 homolog; Plays a role in vesicle-mediated protein trafficking to lysosomal compartments including the endocytic membrane transport pathways; Belongs to the VPS41 family. (805 aa)
	v1g208259	Predicted protein. (477 aa)
	v1g208260	Predicted protein. (373 aa)
	v1g235773	Predicted protein. (795 aa)

Your Current Organism:

Nematostella vectensis

NCBI taxonomy Id: 45351
Other names: N. vectensis, starlet sea anemone

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
v1g184544	v1g208259	A7S1I7	A7S846	Vacuolar protein sorting-associated protein 41 homolog; Plays a role in vesicle-mediated protein trafficking to lysosomal compartments including the endocytic membrane transport pathways; Belongs to the VPS41 family.	Predicted protein.	0.983
v1g184544	v1g208260	A7S1I7	A7S847	Vacuolar protein sorting-associated protein 41 homolog; Plays a role in vesicle-mediated protein trafficking to lysosomal compartments including the endocytic membrane transport pathways; Belongs to the VPS41 family.	Predicted protein.	0.983
v1g184544	v1g228040	A7S1I7	A7RHU4	Vacuolar protein sorting-associated protein 41 homolog; Plays a role in vesicle-mediated protein trafficking to lysosomal compartments including the endocytic membrane transport pathways; Belongs to the VPS41 family.	Vacuolar protein sorting-associated protein 16 homolog; Plays a role in vesicle-mediated protein trafficking to lysosomal compartments including the endocytic membrane transport and autophagic pathways. Believed to act as a core component of the putative HOPS and CORVET endosomal tethering complexes. Belongs to the VPS16 family.	0.998
v1g184544	v1g235773	A7S1I7	A7SPM1	Vacuolar protein sorting-associated protein 41 homolog; Plays a role in vesicle-mediated protein trafficking to lysosomal compartments including the endocytic membrane transport pathways; Belongs to the VPS41 family.	Predicted protein.	0.997
v1g184544	v1g85536	A7S1I7	A7RKZ9	Vacuolar protein sorting-associated protein 41 homolog; Plays a role in vesicle-mediated protein trafficking to lysosomal compartments including the endocytic membrane transport pathways; Belongs to the VPS41 family.	Predicted protein.	0.998
v1g184544	v1g95934	A7S1I7	A7RWL2	Vacuolar protein sorting-associated protein 41 homolog; Plays a role in vesicle-mediated protein trafficking to lysosomal compartments including the endocytic membrane transport pathways; Belongs to the VPS41 family.	Predicted protein; Belongs to the STXBP/unc-18/SEC1 family.	0.895
v1g184544	v1g96025	A7S1I7	A7RWL4	Vacuolar protein sorting-associated protein 41 homolog; Plays a role in vesicle-mediated protein trafficking to lysosomal compartments including the endocytic membrane transport pathways; Belongs to the VPS41 family.	Predicted protein; Belongs to the STXBP/unc-18/SEC1 family.	0.895
v1g208259	v1g184544	A7S846	A7S1I7	Predicted protein.	Vacuolar protein sorting-associated protein 41 homolog; Plays a role in vesicle-mediated protein trafficking to lysosomal compartments including the endocytic membrane transport pathways; Belongs to the VPS41 family.	0.983
v1g208259	v1g208260	A7S846	A7S847	Predicted protein.	Predicted protein.	0.975
v1g208259	v1g228040	A7S846	A7RHU4	Predicted protein.	Vacuolar protein sorting-associated protein 16 homolog; Plays a role in vesicle-mediated protein trafficking to lysosomal compartments including the endocytic membrane transport and autophagic pathways. Believed to act as a core component of the putative HOPS and CORVET endosomal tethering complexes. Belongs to the VPS16 family.	0.982
v1g208259	v1g235773	A7S846	A7SPM1	Predicted protein.	Predicted protein.	0.968
v1g208259	v1g85536	A7S846	A7RKZ9	Predicted protein.	Predicted protein.	0.983
v1g208259	v1g95934	A7S846	A7RWL2	Predicted protein.	Predicted protein; Belongs to the STXBP/unc-18/SEC1 family.	0.803
v1g208259	v1g96025	A7S846	A7RWL4	Predicted protein.	Predicted protein; Belongs to the STXBP/unc-18/SEC1 family.	0.803
v1g208260	v1g184544	A7S847	A7S1I7	Predicted protein.	Vacuolar protein sorting-associated protein 41 homolog; Plays a role in vesicle-mediated protein trafficking to lysosomal compartments including the endocytic membrane transport pathways; Belongs to the VPS41 family.	0.983
v1g208260	v1g208259	A7S847	A7S846	Predicted protein.	Predicted protein.	0.975
v1g208260	v1g228040	A7S847	A7RHU4	Predicted protein.	Vacuolar protein sorting-associated protein 16 homolog; Plays a role in vesicle-mediated protein trafficking to lysosomal compartments including the endocytic membrane transport and autophagic pathways. Believed to act as a core component of the putative HOPS and CORVET endosomal tethering complexes. Belongs to the VPS16 family.	0.982
v1g208260	v1g235773	A7S847	A7SPM1	Predicted protein.	Predicted protein.	0.968
v1g208260	v1g85536	A7S847	A7RKZ9	Predicted protein.	Predicted protein.	0.983
v1g208260	v1g95934	A7S847	A7RWL2	Predicted protein.	Predicted protein; Belongs to the STXBP/unc-18/SEC1 family.	0.803