(13 nodes) Ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway network (Nematostella vectensis)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	v1g87710	Predicted protein. (393 aa)
	v1g161954	Predicted protein. (181 aa)
	v1g224910	Predicted protein. (361 aa)
	v1g151901	Predicted protein; Belongs to the VPS28 family. (81 aa)
	v1g224052	Predicted protein. (234 aa)
	v1g137340	Predicted protein; Belongs to the AAA ATPase family. (284 aa)
	v1g233669	Predicted protein. (190 aa)
	v1g247474	Predicted protein. (396 aa)
	v1g215525	Predicted protein. (622 aa)
	v1g245819	Predicted protein; Belongs to the AAA ATPase family. (442 aa)
	v1g244032	Predicted protein. (431 aa)
	v1g95909	Vacuolar protein sorting-associated protein 28 homolog; Component of the ESCRT-I complex (endosomal sorting complex required for transport I), a regulator of vesicular trafficking process. (207 aa)
	v1g178046	Vacuolar-sorting protein SNF8; Component of the endosomal sorting complex required for transport II (ESCRT-II), which is required for multivesicular body (MVB) formation and sorting of endosomal cargo proteins into MVBs. Belongs to the SNF8 family. (246 aa)

Your Current Organism:

Nematostella vectensis

NCBI taxonomy Id: 45351
Other names: N. vectensis, starlet sea anemone

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
v1g137340	v1g151901	A7SXZ8	A7TA10	Predicted protein; Belongs to the AAA ATPase family.	Predicted protein; Belongs to the VPS28 family.	0.491
v1g137340	v1g161954	A7SXZ8	A7RRM9	Predicted protein; Belongs to the AAA ATPase family.	Predicted protein.	0.585
v1g137340	v1g224052	A7SXZ8	A7T956	Predicted protein; Belongs to the AAA ATPase family.	Predicted protein.	0.430
v1g137340	v1g224910	A7SXZ8	A7TBN0	Predicted protein; Belongs to the AAA ATPase family.	Predicted protein.	0.465
v1g137340	v1g233669	A7SXZ8	A7SWG3	Predicted protein; Belongs to the AAA ATPase family.	Predicted protein.	0.420
v1g137340	v1g244032	A7SXZ8	A7SAT5	Predicted protein; Belongs to the AAA ATPase family.	Predicted protein.	0.677
v1g137340	v1g245819	A7SXZ8	A7SK75	Predicted protein; Belongs to the AAA ATPase family.	Predicted protein; Belongs to the AAA ATPase family.	0.903
v1g137340	v1g87710	A7SXZ8	A7RNF5	Predicted protein; Belongs to the AAA ATPase family.	Predicted protein.	0.430
v1g137340	v1g95909	A7SXZ8	A7RWG8	Predicted protein; Belongs to the AAA ATPase family.	Vacuolar protein sorting-associated protein 28 homolog; Component of the ESCRT-I complex (endosomal sorting complex required for transport I), a regulator of vesicular trafficking process.	0.491
v1g151901	v1g137340	A7TA10	A7SXZ8	Predicted protein; Belongs to the VPS28 family.	Predicted protein; Belongs to the AAA ATPase family.	0.491
v1g151901	v1g161954	A7TA10	A7RRM9	Predicted protein; Belongs to the VPS28 family.	Predicted protein.	0.981
v1g151901	v1g178046	A7TA10	A7RHS4	Predicted protein; Belongs to the VPS28 family.	Vacuolar-sorting protein SNF8; Component of the endosomal sorting complex required for transport II (ESCRT-II), which is required for multivesicular body (MVB) formation and sorting of endosomal cargo proteins into MVBs. Belongs to the SNF8 family.	0.942
v1g151901	v1g215525	A7TA10	A7SPQ8	Predicted protein; Belongs to the VPS28 family.	Predicted protein.	0.565
v1g151901	v1g224052	A7TA10	A7T956	Predicted protein; Belongs to the VPS28 family.	Predicted protein.	0.959
v1g151901	v1g224910	A7TA10	A7TBN0	Predicted protein; Belongs to the VPS28 family.	Predicted protein.	0.439
v1g151901	v1g233669	A7TA10	A7SWG3	Predicted protein; Belongs to the VPS28 family.	Predicted protein.	0.989
v1g151901	v1g244032	A7TA10	A7SAT5	Predicted protein; Belongs to the VPS28 family.	Predicted protein.	0.992
v1g151901	v1g245819	A7TA10	A7SK75	Predicted protein; Belongs to the VPS28 family.	Predicted protein; Belongs to the AAA ATPase family.	0.491
v1g151901	v1g247474	A7TA10	A7SUF4	Predicted protein; Belongs to the VPS28 family.	Predicted protein.	0.976
v1g151901	v1g87710	A7TA10	A7RNF5	Predicted protein; Belongs to the VPS28 family.	Predicted protein.	0.959