(66 nodes) Regulation of canonical Wnt signaling pathway network (Nematostella vectensis)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	v1g88708	Predicted protein. (416 aa)
	v1g161273	Predicted protein; Belongs to the protein kinase superfamily. (347 aa)
	v1g88982	Predicted protein. (260 aa)
	v1g200765	Predicted protein. (175 aa)
	v1g240088	Predicted protein; Belongs to the tumor necrosis factor family. (344 aa)
	v1g92549	Predicted protein. (244 aa)
	v1g182113	Predicted protein. (831 aa)
	v1g97345	Predicted protein. (200 aa)
	v1g183284	Predicted protein. (959 aa)
	v1g241531	Predicted protein. (362 aa)
	v1g184640	Predicted protein. (668 aa)
	v1g242529	Predicted protein. (983 aa)
	v1g229403	Tyrosine-protein kinase receptor. (277 aa)
	v1g207415	Predicted protein. (232 aa)
	v1g208073	Predicted protein. (327 aa)
	v1g243663	RuvB-like helicase; Belongs to the RuvB family. (556 aa)
	v1g110685	Predicted protein. (354 aa)
	v1g209121	Predicted protein. (425 aa)
	v1g209762	Predicted protein. (420 aa)
	v1g211454	Predicted protein. (189 aa)
	v1g170242	Peptidyl-prolyl cis-trans isomerase. (150 aa)
	v1g117726	Predicted protein. (278 aa)
	v1g233227	Predicted protein. (285 aa)
	v1g245445	Predicted protein. (628 aa)
	v1g190252	Predicted protein; Belongs to the protein kinase superfamily. (418 aa)
	v1g120073	Ubiquitin carboxyl-terminal hydrolase. (409 aa)
	v1g245730	Predicted protein. (644 aa)
	v1g120850	Predicted protein; Belongs to the protein kinase superfamily. (427 aa)
	v1g213347	Predicted protein. (358 aa)
	v1g121086	Predicted protein. (183 aa)
	v1g25854	Predicted protein. (186 aa)
	v1g12115	Predicted protein; Belongs to the protein kinase superfamily. (400 aa)
	v1g192152	Predicted protein; Belongs to the protein kinase superfamily. (459 aa)
	v1g173470	Predicted protein. (121 aa)
	v1g216666	Predicted protein. (229 aa)
	v1g134347	Predicted protein; Belongs to the glypican family. (206 aa)
	v1g135081	Predicted protein. (57 aa)
	v1g135116	Bicaudal C-like protein 2. (202 aa)
	v1g135171	Predicted protein. (197 aa)
	v1g135193	Predicted protein. (647 aa)
	v1g18871	Predicted protein. (107 aa)
	v1g71335	Predicted protein; Belongs to the protein kinase superfamily. (247 aa)
	v1g136836	Predicted protein. (464 aa)
	v1g137471	Predicted protein. (209 aa)
	v1g15679	Predicted protein. (156 aa)
	v1g142754	Predicted protein. (276 aa)
	v1g221416	Predicted protein. (234 aa)
	v1g221885	Predicted protein. (121 aa)
	v1g248687	Predicted protein. (468 aa)
	v1g223349	Predicted protein. (191 aa)
	v1g248809	Predicted protein. (246 aa)
	v1g150655	Predicted protein. (120 aa)
	v1g223984	Predicted protein. (146 aa)
	v1g224030	Predicted protein. (166 aa)
	v1g248853	Predicted protein. (304 aa)
	v1g224269	RuvB-like helicase. (128 aa)
	v1g9343	Peptidyl-prolyl cis-trans isomerase. (72 aa)
	v1g225075	Predicted protein. (166 aa)
	v1g78377	RuvB-like helicase. (93 aa)
	v1g225955	Predicted protein. (104 aa)
	v1g157790	Predicted protein. (153 aa)
	v1g81999	Predicted protein; Belongs to the cyclin family. (250 aa)
	v1g159193	Predicted protein. (336 aa)
	v1g238821	Predicted protein. (128 aa)
	v1g86403	Predicted protein. (381 aa)
	v1g179827	Predicted protein. (482 aa)

Your Current Organism:

Nematostella vectensis

NCBI taxonomy Id: 45351
Other names: N. vectensis, starlet sea anemone

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structured XML interaction data, according to the 'PSI-MI' data standard

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a flat-file format describing the coordinates and colors of nodes in the network

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

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a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
v1g110685	v1g134347	A7SA46	A7SVQ0	Predicted protein.	Predicted protein; Belongs to the glypican family.	0.665
v1g110685	v1g88708	A7SA46	A7RPB3	Predicted protein.	Predicted protein.	0.913
v1g120850	v1g242529	A7SJR1	A7S371	Predicted protein; Belongs to the protein kinase superfamily.	Predicted protein.	0.669
v1g12115	v1g159193	A7SNG2	A7RIM1	Predicted protein; Belongs to the protein kinase superfamily.	Predicted protein.	0.542
v1g12115	v1g161273	A7SNG2	A7RPJ6	Predicted protein; Belongs to the protein kinase superfamily.	Predicted protein; Belongs to the protein kinase superfamily.	0.542
v1g12115	v1g182113	A7SNG2	A7RUI9	Predicted protein; Belongs to the protein kinase superfamily.	Predicted protein.	0.653
v1g12115	v1g190252	A7SNG2	A7SIW0	Predicted protein; Belongs to the protein kinase superfamily.	Predicted protein; Belongs to the protein kinase superfamily.	0.794
v1g12115	v1g248853	A7SNG2	A7T9H7	Predicted protein; Belongs to the protein kinase superfamily.	Predicted protein.	0.653
v1g134347	v1g110685	A7SVQ0	A7SA46	Predicted protein; Belongs to the glypican family.	Predicted protein.	0.665
v1g134347	v1g209762	A7SVQ0	A7SBM6	Predicted protein; Belongs to the glypican family.	Predicted protein.	0.665
v1g134347	v1g86403	A7SVQ0	A7RLV4	Predicted protein; Belongs to the glypican family.	Predicted protein.	0.741
v1g134347	v1g88708	A7SVQ0	A7RPB3	Predicted protein; Belongs to the glypican family.	Predicted protein.	0.741
v1g135171	v1g135193	A7SWE0	A7SWE1	Predicted protein.	Predicted protein.	0.559
v1g135193	v1g135171	A7SWE1	A7SWE0	Predicted protein.	Predicted protein.	0.559
v1g137471	v1g159193	A7SY33	A7RIM1	Predicted protein.	Predicted protein.	0.745
v1g137471	v1g161273	A7SY33	A7RPJ6	Predicted protein.	Predicted protein; Belongs to the protein kinase superfamily.	0.745
v1g137471	v1g182113	A7SY33	A7RUI9	Predicted protein.	Predicted protein.	0.996
v1g137471	v1g190252	A7SY33	A7SIW0	Predicted protein.	Predicted protein; Belongs to the protein kinase superfamily.	0.980
v1g137471	v1g248853	A7SY33	A7T9H7	Predicted protein.	Predicted protein.	0.971
v1g142754	v1g159193	A7T257	A7RIM1	Predicted protein.	Predicted protein.	0.637