(59 nodes) Regulation of cellular response to growth factor stimulus network (Nematostella vectensis)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	v1g61034	Predicted protein. (326 aa)
	v1g240041	Predicted protein. (612 aa)
	v1g200866	Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (299 aa)
	v1g201212	Predicted protein. (899 aa)
	v1g240569	Predicted protein. (1782 aa)
	v1g93093	Predicted protein. (296 aa)
	v1g241055	Predicted protein. (913 aa)
	v1g95464	Predicted protein. (98 aa)
	v1g237819	Predicted protein. (579 aa)
	v1g79816	Predicted protein. (219 aa)
	v1g237989	Predicted protein. (668 aa)
	v1g80394	Predicted protein. (76 aa)
	v1g80927	Predicted protein. (90 aa)
	v1g226071	Predicted protein. (133 aa)
	v1g9343	Peptidyl-prolyl cis-trans isomerase. (72 aa)
	v1g224567	Predicted protein. (164 aa)
	v1g224419	Predicted protein. (130 aa)
	v1g150523	Predicted protein. (180 aa)
	v1g150238	Predicted protein. (167 aa)
	v1g141657	Follistatin-like protein. (298 aa)
	v1g175523	Predicted protein. (160 aa)
	v1g175297	Predicted protein. (442 aa)
	v1g13494	Predicted protein. (213 aa)
	v1g193459	Predicted protein. (235 aa)
	v1g40721	Predicted protein. (322 aa)
	v1g129920	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (134 aa)
	v1g215872	Predicted protein. (300 aa)
	v1g213815	Predicted protein. (379 aa)
	v1g15221	Predicted protein. (112 aa)
	v1g118140	Predicted protein. (112 aa)
	v1g170242	Peptidyl-prolyl cis-trans isomerase. (150 aa)
	v1g211454	Predicted protein. (189 aa)
	v1g10501	Predicted protein. (837 aa)
	v1g112784	Predicted protein. (263 aa)
	v1g110153	Mothers against decapentaplegic homolog. (324 aa)
	v1g104327	Predicted protein. (296 aa)
	v1g104199	Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (387 aa)
	v1g242758	Predicted protein. (856 aa)
	v1g103179	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (113 aa)
	v1g242616	Predicted protein. (1332 aa)
	v1g185231	Predicted protein. (343 aa)
	v1g26326	Predicted protein. (163 aa)
	v1g242502	Predicted protein. (1752 aa)
	v1g242499	Sortilin. (743 aa)
	v1g100552	Predicted protein. (228 aa)
	v1g98908	Predicted protein. (247 aa)
	v1g29671	Predicted protein. (73 aa)
	v1g203955	Predicted protein. (244 aa)
	v1g203940	Predicted protein. (225 aa)
	v1g203613	Predicted protein. (393 aa)
	v1g196900	Predicted protein. (890 aa)
	v1g196912	Predicted protein. (225 aa)
	v1g238264	Predicted protein. (250 aa)
	v1g81294	Predicted protein. (1065 aa)
	v1g82785	Predicted protein. (92 aa)
	v1g96522	Predicted protein. (264 aa)
	v1g228195	Predicted protein. (289 aa)
	v1g198482	Predicted protein. (1038 aa)
	v1g39945	Predicted protein. (55 aa)

Your Current Organism:

Nematostella vectensis

NCBI taxonomy Id: 45351
Other names: N. vectensis, starlet sea anemone

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
v1g100552	v1g242758	A7S140	A7S4A8	Predicted protein.	Predicted protein.	0.755
v1g103179	v1g129920	A7S3K1	A7SSH5	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.	0.901
v1g104199	v1g110153	A7S4E9	A7S9K9	Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.	Mothers against decapentaplegic homolog.	0.583
v1g104199	v1g242758	A7S4E9	A7S4A8	Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.	Predicted protein.	0.446
v1g110153	v1g104199	A7S9K9	A7S4E9	Mothers against decapentaplegic homolog.	Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.	0.583
v1g110153	v1g13494	A7S9K9	A7SV44	Mothers against decapentaplegic homolog.	Predicted protein.	0.607
v1g110153	v1g150238	A7S9K9	A7T8I0	Mothers against decapentaplegic homolog.	Predicted protein.	0.607
v1g110153	v1g200866	A7S9K9	A7RR38	Mothers against decapentaplegic homolog.	Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.	0.583
v1g110153	v1g242758	A7S9K9	A7S4A8	Mothers against decapentaplegic homolog.	Predicted protein.	0.632
v1g110153	v1g26326	A7S9K9	A7S373	Mothers against decapentaplegic homolog.	Predicted protein.	0.478
v1g118140	v1g141657	A7SH36	A7T1D7	Predicted protein.	Follistatin-like protein.	0.430
v1g118140	v1g15221	A7SH36	A7SH37	Predicted protein.	Predicted protein.	0.910
v1g118140	v1g242758	A7SH36	A7S4A8	Predicted protein.	Predicted protein.	0.819
v1g118140	v1g95464	A7SH36	A7RW37	Predicted protein.	Predicted protein.	0.586
v1g129920	v1g103179	A7SSH5	A7S3K1	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.	0.901
v1g13494	v1g110153	A7SV44	A7S9K9	Predicted protein.	Mothers against decapentaplegic homolog.	0.607
v1g141657	v1g118140	A7T1D7	A7SH36	Follistatin-like protein.	Predicted protein.	0.430
v1g141657	v1g242758	A7T1D7	A7S4A8	Follistatin-like protein.	Predicted protein.	0.691
v1g141657	v1g39945	A7T1D7	A7RL41	Follistatin-like protein.	Predicted protein.	0.465
v1g150238	v1g110153	A7T8I0	A7S9K9	Predicted protein.	Mothers against decapentaplegic homolog.	0.607