105 items (Nematostella vectensis) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	v1g175862	Transcription initiation factor IIE subunit beta; Recruits TFIIH to the initiation complex and stimulates the RNA polymerase II C-terminal domain kinase and DNA-dependent ATPase activities of TFIIH. Both TFIIH and TFIIE are required for promoter clearance by RNA polymerase. (288 aa)
	v1g248037	Mothers against decapentaplegic homolog. (401 aa)
	v1g137233	Predicted protein. (157 aa)
	v1g136184	Predicted protein. (75 aa)
	MED17	Mediator of RNA polymerase II transcription subunit 17; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (645 aa)
	v1g133899	Predicted protein. (130 aa)
	CBFbeta	Core-binding factor subunit beta. (176 aa)
	v1g132332	Predicted protein. (104 aa)
	v1g132249	Predicted protein. (376 aa)
	v1g10142	Predicted protein. (997 aa)
	v1g217267	Predicted protein. (174 aa)
	v1g217194	Predicted protein. (926 aa)
	v1g130839	Predicted protein. (599 aa)
	v1g173611	Predicted protein. (58 aa)
	v1g127715	Predicted protein. (71 aa)
	MED8	Mediator of RNA polymerase II transcription subunit 8; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (252 aa)
	v1g246137	Mediator of RNA polymerase II transcription subunit 14; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (1638 aa)
	v1g246080	Predicted protein. (56 aa)
	v1g214146	Predicted protein. (747 aa)
	v1g246040	Predicted protein. (255 aa)
	v1g235633	Predicted protein. (335 aa)
	v1g122106	Predicted protein. (707 aa)
	v1g119986	Predicted protein. (249 aa)
	v1g245401	Predicted protein. (263 aa)
	v1g212561	Predicted protein. (160 aa)
	v1g212490	Predicted protein. (969 aa)
	v1g245260	Predicted protein. (690 aa)
	v1g117471	Predicted protein. (701 aa)
	v1g211919	Predicted protein. (328 aa)
	v1g245039	Predicted protein. (190 aa)
	v1g116293	Predicted protein. (113 aa)
	v1g18576	Predicted protein. (113 aa)
	v1g211292	Predicted protein. (249 aa)
	v1g115691	Predicted protein. (421 aa)
	v1g115110	Predicted protein. (280 aa)
	v1g114346	Predicted protein. (61 aa)
	v1g210540	Predicted protein. (155 aa)
	v1g244165	General transcription factor IIH subunit 4; Component of the general transcription and DNA repair factor IIH (TFIIH) core complex which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA. Belongs to the TFB2 family. (471 aa)
	v1g29743	Predicted protein. (70 aa)
	v1g168041	Mothers against decapentaplegic homolog. (423 aa)
	v1g110153	Mothers against decapentaplegic homolog. (324 aa)
	v1g243730	Mediator of RNA polymerase II transcription subunit 31; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (141 aa)
	v1g167568	Predicted protein; Belongs to the cyclin family. (306 aa)
	v1g106438	Predicted protein. (67 aa)
	v1g186169	Predicted protein. (99 aa)
	v1g166645	Predicted protein. (124 aa)
	v1g47437	Predicted protein. (93 aa)
	v1g232694	Predicted protein. (205 aa)
	v1g104726	Predicted protein. (66 aa)
	v1g242787	Predicted protein. (297 aa)
	MED18	Mediator of RNA polymerase II transcription subunit 18; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (162 aa)
	v1g101079	General transcription factor IIH subunit. (400 aa)
	v1g164541	Predicted protein. (511 aa)
	v1g96883	Predicted protein. (734 aa)
	v1g96966	Predicted protein. (146 aa)
	v1g96863	Predicted protein. (182 aa)
	v1g241356	Predicted protein. (231 aa)
	v1g241252	Predicted protein. (306 aa)
	v1g95962	Predicted protein. (135 aa)
	v1g240957	Predicted protein. (174 aa)
	v1g93714	Predicted protein. (116 aa)
	v1g240727	Predicted protein. (255 aa)
	v1g162513	Predicted protein. (662 aa)
	v1g90512	Predicted protein. (160 aa)
	MED4	Mediator of RNA polymerase II transcription subunit 4; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (441 aa)
	v1g180626	Predicted protein. (515 aa)
	v1g200125	Predicted protein. (204 aa)
	MED6	Mediator of RNA polymerase II transcription subunit 6; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (262 aa)
	v1g180316	Predicted protein. (735 aa)
	v1g88215	Predicted protein. (106 aa)
	v1g228395	Mothers against decapentaplegic homolog. (435 aa)
	v1g160110	Predicted protein. (671 aa)
	v1g67237	Predicted protein. (101 aa)
	v1g178700	Predicted protein. (931 aa)
	v1g197956	Predicted protein. (193 aa)
	v1g83420	Predicted protein. (375 aa)
	v1g82906	Transcription initiation factor IIF subunit alpha; TFIIF is a general transcription initiation factor that binds to RNA polymerase II and helps to recruit it to the initiation complex in collaboration with TFIIB. It promotes transcription elongation. Belongs to the TFIIF alpha subunit family. (65 aa)
	v1g82479	Transcription initiation factor IIF subunit alpha; TFIIF is a general transcription initiation factor that binds to RNA polymerase II and helps to recruit it to the initiation complex in collaboration with TFIIB. It promotes transcription elongation. Belongs to the TFIIF alpha subunit family. (177 aa)
	v1g82757	Predicted protein. (81 aa)
	v1g238228	Predicted protein. (542 aa)
	v1g80696	Predicted protein. (82 aa)
	v1g39846	Predicted protein. (59 aa)
	NK-4	Nkx2.5 homeobox transcription factor. (293 aa)
	v1g157164	Predicted protein. (69 aa)
	v1g225715	Predicted protein. (135 aa)
	v1g155676	Predicted protein. (109 aa)
	v1g154049	Predicted protein. (49 aa)
	v1g224761	Predicted protein. (218 aa)
	v1g224692	Predicted protein. (129 aa)
	v1g152277	Predicted protein. (62 aa)
	v1g248844	Predicted protein. (108 aa)
	v1g223755	Predicted protein. (279 aa)
	v1g7672	Predicted protein. (121 aa)
	v1g223038	Predicted protein. (330 aa)
	v1g223037	Predicted protein. (621 aa)
	v1g222894	Predicted protein. (639 aa)
	v1g222886	Predicted protein. (339 aa)
	v1g147480	Predicted protein. (93 aa)
	v1g146211	Predicted protein. (57 aa)
	v1g222302	Predicted protein. (475 aa)
	v1g145097	Predicted protein. (216 aa)
	MED8-2	Mediator of RNA polymerase II transcription subunit 8; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (264 aa)
	v1g141592	Predicted protein. (71 aa)
	v1g139976	Predicted protein. (106 aa)
	v1g138459	Predicted protein. (108 aa)

Your Current Organism:

Nematostella vectensis

NCBI taxonomy Id: 45351
Other names: N. vectensis, starlet sea anemone

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CBFbeta	v1g132332	A7SV13	A7SUJ9	Core-binding factor subunit beta.	Predicted protein.	0.512
CBFbeta	v1g167568	A7SV13	A7S801	Core-binding factor subunit beta.	Predicted protein; Belongs to the cyclin family.	0.529
CBFbeta	v1g248037	A7SV13	A7SY32	Core-binding factor subunit beta.	Mothers against decapentaplegic homolog.	0.617
MED17	MED18	A7SW38	A7S476	Mediator of RNA polymerase II transcription subunit 17; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.	Mediator of RNA polymerase II transcription subunit 18; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.	0.998
MED17	MED4	A7SW38	A7RR67	Mediator of RNA polymerase II transcription subunit 17; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.	Mediator of RNA polymerase II transcription subunit 4; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.	0.995
MED17	MED6	A7SW38	A7RP29	Mediator of RNA polymerase II transcription subunit 17; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.	Mediator of RNA polymerase II transcription subunit 6; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.	0.999
MED17	MED8	A7SW38	A7SP88	Mediator of RNA polymerase II transcription subunit 17; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.	Mediator of RNA polymerase II transcription subunit 8; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.	0.987
MED17	MED8-2	A7SW38	A7T1N3	Mediator of RNA polymerase II transcription subunit 17; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.	Mediator of RNA polymerase II transcription subunit 8; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.	0.987
MED17	v1g101079	A7SW38	A7S1M7	Mediator of RNA polymerase II transcription subunit 17; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.	General transcription factor IIH subunit.	0.866
MED17	v1g10142	A7SW38	A7STW0	Mediator of RNA polymerase II transcription subunit 17; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.	Predicted protein.	0.547
MED17	v1g115691	A7SW38	A7SES2	Mediator of RNA polymerase II transcription subunit 17; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.	Predicted protein.	0.915
MED17	v1g119986	A7SW38	A7SIX2	Mediator of RNA polymerase II transcription subunit 17; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.	Predicted protein.	0.947
MED17	v1g127715	A7SW38	A7SQJ6	Mediator of RNA polymerase II transcription subunit 17; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.	Predicted protein.	0.750
MED17	v1g133899	A7SW38	A7SVA3	Mediator of RNA polymerase II transcription subunit 17; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.	Predicted protein.	0.435
MED17	v1g138459	A7SW38	A7SYY0	Mediator of RNA polymerase II transcription subunit 17; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.	Predicted protein.	0.694
MED17	v1g139976	A7SW38	A7T062	Mediator of RNA polymerase II transcription subunit 17; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.	Predicted protein.	0.435
MED17	v1g146211	A7SW38	A7T515	Mediator of RNA polymerase II transcription subunit 17; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.	Predicted protein.	0.435
MED17	v1g147480	A7SW38	A7T657	Mediator of RNA polymerase II transcription subunit 17; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.	Predicted protein.	0.866
MED17	v1g155676	A7SW38	A8DVA7	Mediator of RNA polymerase II transcription subunit 17; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.	Predicted protein.	0.873
MED17	v1g162513	A7SW38	A7RTJ4	Mediator of RNA polymerase II transcription subunit 17; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.	Predicted protein.	0.600