(14 nodes) Single hybrid motif network (Nematostella vectensis)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	v1g148718	Predicted protein. (113 aa)
	v1g81576	Glycine cleavage system H protein; The H protein shuttles the methylamine group of glycine from the P protein to the T protein; Belongs to the GcvH family. (126 aa)
	v1g232288	Predicted protein. (102 aa)
	v1g90374	Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex. (413 aa)
	v1g178585	Pyruvate carboxylase; Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second. (1200 aa)
	v1g227398	Acetyltransferase component of pyruvate dehydrogenase complex; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). (416 aa)
	v1g216270	Predicted protein. (203 aa)
	v1g8812	Predicted protein. (58 aa)
	v1g171935	Predicted protein. (710 aa)
	v1g190464	Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex. (396 aa)
	v1g208225	Predicted protein. (135 aa)
	v1g20079	Predicted protein. (1093 aa)
	v1g162924	Predicted protein. (711 aa)
	v1g159334	Pyruvate carboxylase; Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second. (1140 aa)

Your Current Organism:

Nematostella vectensis

NCBI taxonomy Id: 45351
Other names: N. vectensis, starlet sea anemone

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
v1g148718	v1g190464	A7T7B6	A7SJI4	Predicted protein.	Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex.	0.410
v1g148718	v1g227398	A7T7B6	A7SQK2	Predicted protein.	Acetyltransferase component of pyruvate dehydrogenase complex; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).	0.410
v1g148718	v1g8812	A7T7B6	A7TBM2	Predicted protein.	Predicted protein.	0.410
v1g159334	v1g178585	A7RIZ0	A7RIZ1	Pyruvate carboxylase; Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second.	Pyruvate carboxylase; Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second.	0.900
v1g159334	v1g20079	A7RIZ0	A7RXZ3	Pyruvate carboxylase; Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second.	Predicted protein.	0.475
v1g159334	v1g227398	A7RIZ0	A7SQK2	Pyruvate carboxylase; Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second.	Acetyltransferase component of pyruvate dehydrogenase complex; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).	0.841
v1g162924	v1g20079	A7RUP0	A7RXZ3	Predicted protein.	Predicted protein.	0.513
v1g162924	v1g90374	A7RUP0	A7RQN7	Predicted protein.	Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex.	0.500
v1g171935	v1g20079	A7SLP5	A7RXZ3	Predicted protein.	Predicted protein.	0.518
v1g171935	v1g90374	A7SLP5	A7RQN7	Predicted protein.	Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex.	0.500
v1g178585	v1g159334	A7RIZ1	A7RIZ0	Pyruvate carboxylase; Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second.	Pyruvate carboxylase; Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second.	0.900
v1g178585	v1g20079	A7RIZ1	A7RXZ3	Pyruvate carboxylase; Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second.	Predicted protein.	0.475
v1g178585	v1g227398	A7RIZ1	A7SQK2	Pyruvate carboxylase; Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second.	Acetyltransferase component of pyruvate dehydrogenase complex; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).	0.841
v1g190464	v1g148718	A7SJI4	A7T7B6	Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex.	Predicted protein.	0.410
v1g190464	v1g227398	A7SJI4	A7SQK2	Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex.	Acetyltransferase component of pyruvate dehydrogenase complex; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).	0.565
v1g190464	v1g81576	A7SJI4	A7RHF2	Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex.	Glycine cleavage system H protein; The H protein shuttles the methylamine group of glycine from the P protein to the T protein; Belongs to the GcvH family.	0.796
v1g190464	v1g8812	A7SJI4	A7TBM2	Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex.	Predicted protein.	0.544
v1g190464	v1g90374	A7SJI4	A7RQN7	Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex.	Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex.	0.572
v1g20079	v1g159334	A7RXZ3	A7RIZ0	Predicted protein.	Pyruvate carboxylase; Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second.	0.475
v1g20079	v1g162924	A7RXZ3	A7RUP0	Predicted protein.	Predicted protein.	0.513