(6 nodes) Sirtuin, catalytic core small domain superfamily network (Nematostella vectensis)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	v1g136467	Predicted protein. (306 aa)
	v1g83259	Predicted protein. (285 aa)
	v1g179325	Predicted protein. (335 aa)
	v1g86891	NAD-dependent protein deacylase; NAD-dependent lysine demalonylase, desuccinylase and deglutarylase that specifically removes malonyl, succinyl and glutaryl groups on target proteins. Has weak NAD-dependent protein deacetylase activity; however this activity may not be physiologically relevant in vivo. (273 aa)
	v1g228435	NAD-dependent protein deacetylase; Belongs to the sirtuin family. Class I subfamily. (310 aa)
	v1g190741	Predicted protein. (323 aa)

Your Current Organism:

Nematostella vectensis

NCBI taxonomy Id: 45351
Other names: N. vectensis, starlet sea anemone

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
v1g136467	v1g179325	A7SX90	A7RLD5	Predicted protein.	Predicted protein.	0.556
v1g136467	v1g190741	A7SX90	A7SK95	Predicted protein.	Predicted protein.	0.629
v1g136467	v1g228435	A7SX90	A7RNW2	Predicted protein.	NAD-dependent protein deacetylase; Belongs to the sirtuin family. Class I subfamily.	0.551
v1g136467	v1g83259	A7SX90	A7RIU3	Predicted protein.	Predicted protein.	0.549
v1g179325	v1g136467	A7RLD5	A7SX90	Predicted protein.	Predicted protein.	0.556
v1g179325	v1g190741	A7RLD5	A7SK95	Predicted protein.	Predicted protein.	0.566
v1g179325	v1g86891	A7RLD5	A7RMK8	Predicted protein.	NAD-dependent protein deacylase; NAD-dependent lysine demalonylase, desuccinylase and deglutarylase that specifically removes malonyl, succinyl and glutaryl groups on target proteins. Has weak NAD-dependent protein deacetylase activity; however this activity may not be physiologically relevant in vivo.	0.602
v1g190741	v1g136467	A7SK95	A7SX90	Predicted protein.	Predicted protein.	0.629
v1g190741	v1g179325	A7SK95	A7RLD5	Predicted protein.	Predicted protein.	0.566
v1g190741	v1g228435	A7SK95	A7RNW2	Predicted protein.	NAD-dependent protein deacetylase; Belongs to the sirtuin family. Class I subfamily.	0.560
v1g190741	v1g83259	A7SK95	A7RIU3	Predicted protein.	Predicted protein.	0.555
v1g190741	v1g86891	A7SK95	A7RMK8	Predicted protein.	NAD-dependent protein deacylase; NAD-dependent lysine demalonylase, desuccinylase and deglutarylase that specifically removes malonyl, succinyl and glutaryl groups on target proteins. Has weak NAD-dependent protein deacetylase activity; however this activity may not be physiologically relevant in vivo.	0.620
v1g228435	v1g136467	A7RNW2	A7SX90	NAD-dependent protein deacetylase; Belongs to the sirtuin family. Class I subfamily.	Predicted protein.	0.551
v1g228435	v1g190741	A7RNW2	A7SK95	NAD-dependent protein deacetylase; Belongs to the sirtuin family. Class I subfamily.	Predicted protein.	0.560
v1g228435	v1g86891	A7RNW2	A7RMK8	NAD-dependent protein deacetylase; Belongs to the sirtuin family. Class I subfamily.	NAD-dependent protein deacylase; NAD-dependent lysine demalonylase, desuccinylase and deglutarylase that specifically removes malonyl, succinyl and glutaryl groups on target proteins. Has weak NAD-dependent protein deacetylase activity; however this activity may not be physiologically relevant in vivo.	0.598
v1g83259	v1g136467	A7RIU3	A7SX90	Predicted protein.	Predicted protein.	0.549
v1g83259	v1g190741	A7RIU3	A7SK95	Predicted protein.	Predicted protein.	0.555
v1g83259	v1g86891	A7RIU3	A7RMK8	Predicted protein.	NAD-dependent protein deacylase; NAD-dependent lysine demalonylase, desuccinylase and deglutarylase that specifically removes malonyl, succinyl and glutaryl groups on target proteins. Has weak NAD-dependent protein deacetylase activity; however this activity may not be physiologically relevant in vivo.	0.596
v1g86891	v1g179325	A7RMK8	A7RLD5	NAD-dependent protein deacylase; NAD-dependent lysine demalonylase, desuccinylase and deglutarylase that specifically removes malonyl, succinyl and glutaryl groups on target proteins. Has weak NAD-dependent protein deacetylase activity; however this activity may not be physiologically relevant in vivo.	Predicted protein.	0.602
v1g86891	v1g190741	A7RMK8	A7SK95	NAD-dependent protein deacylase; NAD-dependent lysine demalonylase, desuccinylase and deglutarylase that specifically removes malonyl, succinyl and glutaryl groups on target proteins. Has weak NAD-dependent protein deacetylase activity; however this activity may not be physiologically relevant in vivo.	Predicted protein.	0.620