(31 nodes) Translesion synthesis by POLK network (Nematostella vectensis)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	v1g231426	Predicted protein. (501 aa)
	v1g225793	Predicted protein. (340 aa)
	v1g225758	Predicted protein. (115 aa)
	v1g152288	Predicted protein. (90 aa)
	v1g148076	Predicted protein. (224 aa)
	v1g222714	Predicted protein. (442 aa)
	v1g248724	Predicted protein. (902 aa)
	v1g145228	Predicted protein. (64 aa)
	v1g217964	Predicted protein. (229 aa)
	v1g217764	Predicted protein. (533 aa)
	v1g132328	Predicted protein. (793 aa)
	v1g123409	Predicted protein. (95 aa)
	v1g171280	Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage. (626 aa)
	v1g244659	Predicted protein. (2095 aa)
	v1g210850	Predicted protein. (866 aa)
	v1g210048	Predicted protein. (209 aa)
	v1g21291	Predicted protein. (483 aa)
	v1g209082	Predicted protein. (401 aa)
	v1g209079	Predicted protein. (108 aa)
	v1g207988	Predicted protein. (376 aa)
	v1g166966	Predicted protein. (355 aa)
	v1g166761	Predicted protein. (357 aa)
	v1g166542	Predicted protein. (329 aa)
	v1g102068	Predicted protein. (265 aa)
	v1g102086	DNA polymerase. (497 aa)
	v1g201793	Predicted protein. (586 aa)
	v1g201791	Predicted protein. (753 aa)
	v1g162231	Predicted protein. (147 aa)
	v1g159364	Predicted protein. (157 aa)
	v1g236362	Predicted protein. (114 aa)
	v1g30213	Predicted protein. (870 aa)

Your Current Organism:

Nematostella vectensis

NCBI taxonomy Id: 45351
Other names: N. vectensis, starlet sea anemone

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structured XML interaction data, according to the 'PSI-MI' data standard

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node degree of proteins in your network (given the current score cut-off)

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a flat-file format describing the coordinates and colors of nodes in the network

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

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a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
v1g102068	v1g102086	A7S2K2	A7S2J9	Predicted protein.	DNA polymerase.	0.964
v1g102068	v1g132328	A7S2K2	A7SUL3	Predicted protein.	Predicted protein.	0.617
v1g102068	v1g145228	A7S2K2	A7T469	Predicted protein.	Predicted protein.	0.552
v1g102068	v1g148076	A7S2K2	A7T6P5	Predicted protein.	Predicted protein.	0.648
v1g102068	v1g166542	A7S2K2	A7S523	Predicted protein.	Predicted protein.	0.684
v1g102068	v1g166761	A7S2K2	A7S5R5	Predicted protein.	Predicted protein.	0.684
v1g102068	v1g166966	A7S2K2	A7S695	Predicted protein.	Predicted protein.	0.684
v1g102068	v1g171280	A7S2K2	A7SJL0	Predicted protein.	Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage.	0.549
v1g102068	v1g209079	A7S2K2	A7SA23	Predicted protein.	Predicted protein.	0.626
v1g102068	v1g209082	A7S2K2	A7SA25	Predicted protein.	Predicted protein.	0.626
v1g102068	v1g210048	A7S2K2	A7SC91	Predicted protein.	Predicted protein.	0.989
v1g102068	v1g210850	A7S2K2	A7SE42	Predicted protein.	Predicted protein.	0.532
v1g102068	v1g21291	A7S2K2	A7SB19	Predicted protein.	Predicted protein.	0.751
v1g102068	v1g222714	A7S2K2	A7T5T5	Predicted protein.	Predicted protein.	0.617
v1g102068	v1g225758	A7S2K2	A8DVN3	Predicted protein.	Predicted protein.	0.549
v1g102068	v1g225793	A7S2K2	A8DVS3	Predicted protein.	Predicted protein.	0.648
v1g102068	v1g231426	A7S2K2	A7T4A2	Predicted protein.	Predicted protein.	0.751
v1g102068	v1g236362	A7S2K2	A7RHZ6	Predicted protein.	Predicted protein.	0.610
v1g102068	v1g244659	A7S2K2	A7SEA4	Predicted protein.	Predicted protein.	0.548
v1g102068	v1g248724	A7S2K2	A7T529	Predicted protein.	Predicted protein.	0.548