| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| Igni_0036 | Igni_0331 | Igni_0036 | Igni_0331 | TIGRFAM: anaerobic ribonucleoside-triphosphate reductase. | CTP synthase; PFAM: glutamine amidotransferase class-I; CTP synthase. | 0.910 |
| Igni_0036 | Igni_0507 | Igni_0036 | Igni_0507 | TIGRFAM: anaerobic ribonucleoside-triphosphate reductase. | TIGRFAM: putative adenylyl cyclase CyaB; PFAM: adenylate cyclase. | 0.900 |
| Igni_0036 | Igni_0585 | Igni_0036 | Igni_0585 | TIGRFAM: anaerobic ribonucleoside-triphosphate reductase. | TIGRFAM: deoxyuridine 5'-triphosphate nucleotidohydrolase Dut; PFAM: deoxyUTP pyrophosphatase. | 0.903 |
| Igni_0036 | Igni_1066 | Igni_0036 | Igni_1066 | TIGRFAM: anaerobic ribonucleoside-triphosphate reductase. | Protein of unknown function DUF265; Has nucleotide phosphatase activity towards ATP, GTP, CTP, TTP and UTP. May hydrolyze nucleoside diphosphates with lower efficiency; Belongs to the THEP1 NTPase family. | 0.908 |
| Igni_0036 | Igni_1352 | Igni_0036 | Igni_1352 | TIGRFAM: anaerobic ribonucleoside-triphosphate reductase. | GTP cyclohydrolase Iia. | 0.800 |
| Igni_0036 | Igni_1422 | Igni_0036 | Igni_1422 | TIGRFAM: anaerobic ribonucleoside-triphosphate reductase. | Thymidylate synthase, flavin-dependent; Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NADPH and FADH(2) as the reductant. | 0.481 |
| Igni_0036 | dcd | Igni_0036 | Igni_0224 | TIGRFAM: anaerobic ribonucleoside-triphosphate reductase. | dCTP deaminase; Catalyzes the deamination of dCTP to dUTP. | 0.903 |
| Igni_0036 | ndk | Igni_0036 | Igni_0725 | TIGRFAM: anaerobic ribonucleoside-triphosphate reductase. | Nucleoside diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate. | 0.916 |
| Igni_0222 | Igni_0957 | Igni_0222 | Igni_0957 | Nucleotide kinase-like protein; Related to CMP and AMP kinase. | Hypothetical protein. | 0.900 |
| Igni_0222 | Igni_1066 | Igni_0222 | Igni_1066 | Nucleotide kinase-like protein; Related to CMP and AMP kinase. | Protein of unknown function DUF265; Has nucleotide phosphatase activity towards ATP, GTP, CTP, TTP and UTP. May hydrolyze nucleoside diphosphates with lower efficiency; Belongs to the THEP1 NTPase family. | 0.924 |
| Igni_0222 | adkA | Igni_0222 | Igni_1198 | Nucleotide kinase-like protein; Related to CMP and AMP kinase. | Adenylate kinase-like protein; Belongs to the archaeal adenylate kinase family. | 0.900 |
| Igni_0222 | ndk | Igni_0222 | Igni_0725 | Nucleotide kinase-like protein; Related to CMP and AMP kinase. | Nucleoside diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate. | 0.900 |
| Igni_0331 | Igni_0036 | Igni_0331 | Igni_0036 | CTP synthase; PFAM: glutamine amidotransferase class-I; CTP synthase. | TIGRFAM: anaerobic ribonucleoside-triphosphate reductase. | 0.910 |
| Igni_0331 | Igni_1422 | Igni_0331 | Igni_1422 | CTP synthase; PFAM: glutamine amidotransferase class-I; CTP synthase. | Thymidylate synthase, flavin-dependent; Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NADPH and FADH(2) as the reductant. | 0.460 |
| Igni_0331 | dcd | Igni_0331 | Igni_0224 | CTP synthase; PFAM: glutamine amidotransferase class-I; CTP synthase. | dCTP deaminase; Catalyzes the deamination of dCTP to dUTP. | 0.919 |
| Igni_0331 | ndk | Igni_0331 | Igni_0725 | CTP synthase; PFAM: glutamine amidotransferase class-I; CTP synthase. | Nucleoside diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate. | 0.947 |
| Igni_0507 | Igni_0036 | Igni_0507 | Igni_0036 | TIGRFAM: putative adenylyl cyclase CyaB; PFAM: adenylate cyclase. | TIGRFAM: anaerobic ribonucleoside-triphosphate reductase. | 0.900 |
| Igni_0507 | Igni_1066 | Igni_0507 | Igni_1066 | TIGRFAM: putative adenylyl cyclase CyaB; PFAM: adenylate cyclase. | Protein of unknown function DUF265; Has nucleotide phosphatase activity towards ATP, GTP, CTP, TTP and UTP. May hydrolyze nucleoside diphosphates with lower efficiency; Belongs to the THEP1 NTPase family. | 0.900 |
| Igni_0507 | Igni_1352 | Igni_0507 | Igni_1352 | TIGRFAM: putative adenylyl cyclase CyaB; PFAM: adenylate cyclase. | GTP cyclohydrolase Iia. | 0.800 |
| Igni_0507 | ndk | Igni_0507 | Igni_0725 | TIGRFAM: putative adenylyl cyclase CyaB; PFAM: adenylate cyclase. | Nucleoside diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate. | 0.900 |