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| | dtdA | Protein of unknown function DUF516; D-aminoacyl-tRNA deacylase with broad substrate specificity. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo. (245 aa) |
| | metG | methionyl-tRNA synthetase; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation; Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 1 subfamily. (561 aa) |
| | Igni_1157 | Hypothetical protein. (242 aa) |
| | Igni_1171 | PFAM: beta-lactamase domain protein. (240 aa) |
| | Igni_1189 | PFAM: Mandelate racemase/muconate lactonizing enzyme, C-terminal domain protein. (377 aa) |
| | thrB | Homoserine kinase; Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate; Belongs to the GHMP kinase family. Homoserine kinase subfamily. (301 aa) |
| | Igni_1210 | Hypothetical protein. (294 aa) |
| | Igni_1226 | TIGRFAM: phenylalanyl-tRNA synthetase, beta subunit; PFAM: tRNA synthetase, B5. (529 aa) |
| | Igni_1227 | TIGRFAM: phenylalanyl-tRNA synthetase, alpha subunit; PFAM: phenylalanyl-tRNA synthetase, class IIc. (478 aa) |
| | Igni_1228 | TIGRFAM: glutamine synthetase, type I; PFAM: glutamine synthetase, catalytic region; glutamine synthetase, beta-Grasp. (497 aa) |
| | Igni_1246 | PFAM: Amidohydrolase 3. (383 aa) |
| | leuD-2 | 3-isopropylmalate dehydratase, small subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. Belongs to the LeuD family. LeuD type 2 subfamily. (175 aa) |
| | Igni_1249 | TIGRFAM: homocitrate synthase; PFAM: regulatory protein, AsnC/Lrp family; pyruvate carboxyltransferase; Belongs to the alpha-IPM synthase/homocitrate synthase family. (477 aa) |
| | Igni_1256 | TIGRFAM: pyruvate/ketoisovalerate oxidoreductase, gamma subunit; PFAM: pyruvate ferredoxin/flavodoxin oxidoreductase. (189 aa) |
| | Igni_1257 | TIGRFAM: pyruvate ferredoxin/flavodoxin oxidoreductase, delta subunit; PFAM: 4Fe-4S ferredoxin, iron-sulfur binding domain protein. (102 aa) |
| | Igni_1263 | PFAM: Lactate/malate dehydrogenase; Belongs to the LDH/MDH superfamily. (311 aa) |
| | Igni_1267 | PFAM: Transketolase domain protein. (279 aa) |
| | aroA | 3-phosphoshikimate 1-carboxyvinyltransferase; Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate. (443 aa) |
| | Igni_1301 | TIGRFAM: tryptophanyl-tRNA synthetase; PFAM: aminoacyl-tRNA synthetase, class Ib. (379 aa) |
| | Igni_1317 | PFAM: t-RNA-binding domain protein. (219 aa) |
| | Igni_1329 | PFAM: Indole-3-glycerol phosphate synthase. (254 aa) |
| | Igni_1333 | Histidinol phosphate aminotransferase; PFAM: aminotransferase, class I and II. (355 aa) |
| | guaAA | Glutamine amidotransferase class-I; Catalyzes the synthesis of GMP from XMP. (188 aa) |
| | apgM | Phosphoglycerate mutase; Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate. (416 aa) |
| | Igni_1379 | Putative nitrate reductase, subunit A; PFAM: molybdopterin oxidoreductase; molydopterin dinucleotide-binding region; molybdopterin oxidoreductase Fe4S4 region. (1249 aa) |
| | Igni_1382 | TIGRFAM: lysine 2,3-aminomutase YodO family protein; PFAM: Radical SAM domain protein. (621 aa) |
| | arcB | Ornithine carbamoyltransferase; Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. OTCase family. (311 aa) |
| | Igni_1399 | TIGRFAM: carbamoyl-phosphate synthase, large subunit; PFAM: phosphoribosylglycinamide synthetase; ATP-dependent carboxylate-amine ligase domain protein, ATP-grasp; protein of unknown function DUF201; Carbamoyl-phosphate synthase L chain, ATP-binding; Carbamoyl-phosphate synthetase large chain, oligomerisation; Carbamoyl-phosphate synthetase large chain domain protein. (1047 aa) |
| | carA | TIGRFAM: carbamoyl-phosphate synthase, small subunit; PFAM: glutamine amidotransferase class-I; Carbamoyl-phosphate synthase, small chain; Belongs to the CarA family. (373 aa) |
| | Igni_1401 | TIGRFAM: acetyl-CoA acetyltransferase; PFAM: Thiolase. (396 aa) |
| | Igni_1402 | Hypothetical protein. (56 aa) |
| | Igni_1403 | Lysine biosynthesis enzyme LysX; TIGRFAM: alpha-L-glutamate ligase, RimK family; lysine biosynthesis enzyme LysX; PFAM: protein of unknown function DUF201; RimK domain protein ATP-grasp. (285 aa) |
| | Igni_1430 | TIGRFAM: argininosuccinate lyase; PFAM: fumarate lyase. (452 aa) |
| | aspS | aspartyl-tRNA synthetase; Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp/Asn). (453 aa) |
| | Igni_1436 | 3-deoxy-D-arabinoheptulosonate-7-phosphate synthase; TIGRFAM: phospho-2-dehydro-3-deoxyheptonate aldolase; PFAM: DAHP synthetase I/KDSA. (332 aa) |
| | trpD | Anthranilate phosphoribosyltransferase; Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'- phosphoribosyl)-anthranilate (PRA). (339 aa) |
| | Igni_0002 | PFAM: FAD linked oxidase domain protein. (433 aa) |
| | aroB | 3-dehydroquinate synthase; Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ); Belongs to the sugar phosphate cyclases superfamily. Dehydroquinate synthase family. (367 aa) |
| | Igni_0019 | PFAM: ProFAR isomerase family protein. (236 aa) |
| | hisE | PFAM: phosphoribosyl-ATP pyrophosphohydrolase. (102 aa) |
| | hisH | Imidazole glycerol phosphate synthase subunit hisH; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF. (197 aa) |
| | Igni_0041 | PFAM: PfkB domain protein; Belongs to the carbohydrate kinase PfkB family. (297 aa) |
| | pyrB | TIGRFAM: aspartate carbamoyltransferase; PFAM: aspartate/ornithine carbamoyltransferase, Asp/Orn-binding region; aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain. (305 aa) |
| | Igni_0057 | L-2-aminoadipate N-acetyltransferase; TIGRFAM: alpha-L-glutamate ligase, RimK family; lysine biosynthesis enzyme LysX; PFAM: protein of unknown function DUF201; RimK domain protein ATP-grasp. (281 aa) |
| | Igni_0090 | Uroporphyrinogen III synthase HEM4; Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III. (234 aa) |
| | Igni_0110 | PFAM: t-RNA-binding domain protein. (111 aa) |
| | Igni_0122 | PFAM: regulatory protein, AsnC/Lrp family; regulatory protein, DeoR; Helix-turn-helix, type 11 domain protein. (182 aa) |
| | Igni_0123 | Glutamine amidotransferase-like protein. (205 aa) |
| | leuS | TIGRFAM: leucyl-tRNA synthetase; Belongs to the class-I aminoacyl-tRNA synthetase family. (1022 aa) |
| | pdxT | SNO glutamine amidotransferase; Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS. (200 aa) |
| | Igni_0168 | SSU ribosomal protein S6P modification protein; TIGRFAM: alpha-L-glutamate ligase, RimK family; PFAM: protein of unknown function DUF201; RimK domain protein ATP-grasp. (293 aa) |
| | Igni_0171 | Glutamine--fructose-6-phosphate transaminase; TIGRFAM: glucosamine--fructose-6-phosphate aminotransferase, isomerizing; PFAM: glutamine amidotransferase, class-II; sugar isomerase (SIS). (592 aa) |
| | Igni_0177 | 1-(5-phosphoribosyl)-5-((5- phosphoribosylamino)methylideneamino) imidazole-4-carboxamide isomerase; PFAM: histidine biosynthesis protein; Belongs to the HisA/HisF family. (235 aa) |
| | alaS | alanyl-tRNA synthetase; Catalyzes the attachment of alanine to tRNA(Ala) in a two- step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain. (901 aa) |
| | Igni_0199 | TIGRFAM: aspartate kinase; PFAM: aspartate/glutamate/uridylate kinase; Belongs to the aspartokinase family. (461 aa) |
| | gatD | glutamyl-tRNA(Gln) amidotransferase subunit D; Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu- tRNA(Gln). The GatDE system is specific for glutamate and does not act on aspartate. (442 aa) |
| | aroE | Shikimate dehydrogenase; Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA). (262 aa) |
| | Igni_0220 | valyl-tRNA synthetase. (792 aa) |
| | Igni_0242 | TIGRFAM: HAD-superfamily hydrolase, subfamily IB (PSPase-like); PFAM: Haloacid dehalogenase domain protein hydrolase. (208 aa) |
| | Igni_0256 | PFAM: AMP-dependent synthetase and ligase. (412 aa) |
| | Igni_0257 | Acyl-coenzyme A synthetase/AMP-(fatty) acid ligase-like protein. (233 aa) |
| | Igni_0261 | PFAM: pyruvate carboxyltransferase. (488 aa) |
| | pgk | PFAM: phosphoglycerate kinase; Belongs to the phosphoglycerate kinase family. (408 aa) |
| | aroD | 3-dehydroquinate dehydratase; Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis- dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3-dehydroshikimate. Belongs to the type-I 3-dehydroquinase family. (215 aa) |
| | leuD | 3-isopropylmalate dehydratase, small subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. Belongs to the LeuD family. LeuD type 2 subfamily. (186 aa) |
| | Igni_0307 | PFAM: prephenate dehydratase; amino acid-binding ACT domain protein. (311 aa) |
| | Igni_0315 | TIGRFAM: acetylornithine deacetylase or succinyl-diaminopimelate desuccinylase; PFAM: peptidase M20; peptidase dimerisation domain protein. (385 aa) |
| | Igni_0331 | CTP synthase; PFAM: glutamine amidotransferase class-I; CTP synthase. (519 aa) |
| | Igni_0341 | Phosphoenolpyruvate carboxylase; PFAM: protein of unknown function DUF557. (488 aa) |
| | Igni_0344 | Phosphoenolpyruvate synthase; PFAM: B3/4 domain protein. (219 aa) |
| | tyrS | tyrosyl-tRNA synthetase; Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two- step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr); Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 4 subfamily. (378 aa) |
| | proS | prolyl-tRNA synthetase; Catalyzes the attachment of proline to tRNA(Pro) in a two- step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro). (478 aa) |
| | Igni_0377 | Acetyl-CoA acetyltransferase-like protein. (353 aa) |
| | Igni_0383 | PFAM: D-isomer specific 2-hydroxyacid dehydrogenase, catalytic region; D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding. (308 aa) |
| | Igni_0384 | Histidinol dehydrogenase; Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine. (404 aa) |
| | panB | 3-methyl-2-oxobutanoate hydroxymethyltransferase; Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha- ketoisovalerate to form ketopantoate; Belongs to the PanB family. (263 aa) |
| | Igni_0398 | PFAM: amidohydrolase. (379 aa) |
| | Igni_0407 | Glutamate synthase (NADPH) GltB1 subunit; PFAM: glutamine amidotransferase, class-II. (296 aa) |
| | Igni_0408 | Ferredoxin-dependent glutamate synthase; PFAM: 4Fe-4S ferredoxin, iron-sulfur binding domain protein; glutamate synthase, alpha subunit domain protein; ferredoxin-dependent glutamate synthase. (717 aa) |
| | Igni_0415 | PFAM: glucose-6-phosphate isomerase. (216 aa) |
| | Igni_0431 | TIGRFAM: tryptophan synthase, alpha subunit; PFAM: tryptophan synthase, alpha chain. (250 aa) |
| | lysS | TIGRFAM: lysyl-tRNA synthetase; PFAM: Lysyl-tRNA synthetase, class 1c; Belongs to the class-I aminoacyl-tRNA synthetase family. (496 aa) |
| | Igni_0468 | PFAM: beta-lactamase domain protein. (229 aa) |
| | Igni_0475 | Coenzyme F390 synthetase-like protein. (493 aa) |
| | Igni_0494 | PFAM: regulatory protein, AsnC/Lrp family; regulatory protein, ArsR; helix-turn-helix, Fis-type; Helix-turn-helix, type 11 domain protein. (152 aa) |
| | Igni_0496 | PFAM: methylenetetrahydrofolate reductase. (329 aa) |
| | Igni_0519 | Translation initiation factor 2B subunit I family (IF-2BI); Catalyzes the interconversion of methylthioribose-1-phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P). Belongs to the EIF-2B alpha/beta/delta subunits family. MtnA subfamily. (351 aa) |
| | Igni_0521 | TIGRFAM: acetylornithine deacetylase or succinyl-diaminopimelate desuccinylase; PFAM: peptidase M20; peptidase dimerisation domain protein. (385 aa) |
| | aroC | Chorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system. (380 aa) |
| | aroK | TIGRFAM: shikimate kinase; PFAM: GHMP kinase; GHMP kinase, C terminal domain protein. (272 aa) |
| | Igni_0554 | TIGRFAM: phosphopantothenoylcysteine decarboxylase/phosphopantothenate--cysteine ligase; PFAM: flavoprotein; DNA/pantothenate metabolism flavoprotein domain protein. (400 aa) |
| | hisI | phosphoribosyl-AMP cyclohydrolase; Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP. (129 aa) |
| | Igni_0568 | TIGRFAM: glycyl-tRNA synthetase; PFAM: tRNA synthetase, class II (G, H, P and S); Anticodon-binding domain protein. (580 aa) |
| | Igni_0570 | TIGRFAM: asparagine synthase (glutamine-hydrolyzing); PFAM: glutamine amidotransferase, class-II; asparagine synthase. (610 aa) |
| | Igni_0580 | PFAM: Pyridoxal-5'-phosphate-dependent enzyme, beta subunit. (313 aa) |
| | Igni_0595 | Vinylacetyl-CoA Delta-isomerase; PFAM: 4-hydroxyphenylacetate 3-hydroxylase. (512 aa) |
| | Igni_0600 | Amidophosphoribosyltransferase; PFAM: phosphoribosyltransferase; In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family. (424 aa) |
| | ilvC | Ketol-acid reductoisomerase; Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate. (343 aa) |
| | lysZ | N2-acetyl-L-aminoadipate kinase; Involved in both the arginine and lysine biosynthetic pathways. Phosphorylates the LysW-bound precursors glutamate (for arginine biosynthesis), respectively alpha-aminoadipate (for lysine biosynthesis); Belongs to the acetylglutamate kinase family. LysZ subfamily. (264 aa) |
| | argG | PFAM: argininosuccinate synthase; ExsB family protein; Belongs to the argininosuccinate synthase family. Type 1 subfamily. (396 aa) |
| | Igni_0641 | TIGRFAM: quinolinate synthetase complex, A subunit; PFAM: Quinolinate synthetase A. (306 aa) |
| | Igni_0645 | TIGRFAM: 2-isopropylmalate synthase/homocitrate synthase family protein; PFAM: pyruvate carboxyltransferase; LeuA allosteric (dimerisation) domain; Belongs to the alpha-IPM synthase/homocitrate synthase family. (547 aa) |
| | proC | Pyrroline-5-carboxylate reductase; Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline. (245 aa) |
| | lysK | N2-acetyl-L-lysine deacetylase; Catalyzes the release of L-lysine from [LysW]-gamma-L-lysine and the release of L-ornithine from [LysW]-L-ornithine. (339 aa) |
| | Igni_0686 | S-adenosylmethionine decarboxylase related; Specifically catalyzes the decarboxylation of L-arginine to agmatine. Has no S-adenosylmethionine decarboxylase (AdoMetDC) activity; Belongs to the prokaryotic AdoMetDC family. Type 1 subfamily. (144 aa) |
| | Igni_0689 | PFAM: Creatininase. (250 aa) |
| | Igni_0694 | PFAM: protein of unknown function DUF126. (152 aa) |
| | Igni_0695 | Aconitase subunit 1; PFAM: protein of unknown function DUF521. (381 aa) |
| | tpiA | Triosephosphate isomerase; Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P); Belongs to the triosephosphate isomerase family. (222 aa) |
| | Igni_0706 | PFAM: regulatory protein, AsnC/Lrp family. (154 aa) |
| | lysY | N2-acetyl-L-aminoadipate semialdehyde dehydrogenase; Involved in both the arginine and lysine biosynthetic pathways; Belongs to the NAGSA dehydrogenase family. Type 1 subfamily. LysY sub-subfamily. (356 aa) |
| | metE | Methionine synthase (B12-independent); Catalyzes the transfer of a methyl group to L-homocysteine resulting in methionine formation. The physiological methyl donor is unknown. (341 aa) |
| | Igni_0748 | PFAM: Methionine synthase, vitamin-B12 independent; Cobalamin-independent synthase MetE, N-terminal domain protein. (332 aa) |
| | Igni_0752 | TIGRFAM: aspartate-semialdehyde dehydrogenase; PFAM: Semialdehyde dehydrogenase, NAD - binding; Semialdehyde dehydrogenase, dimerisation region. (359 aa) |
| | hisG | ATP phosphoribosyltransferase (homohexameric); Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity. Belongs to the ATP phosphoribosyltransferase family. Long subfamily. (283 aa) |
| | hisF | Imidazole glycerol phosphate synthase subunit hisF; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit. (255 aa) |
| | Igni_0805 | PFAM: imidazoleglycerol-phosphate dehydratase. (189 aa) |
| | Igni_0832 | Uncharacterized protein putative amidase-like protein. (225 aa) |
| | purQ | Phosphoribosylformylglycinamidine synthase I; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought to assist i [...] (219 aa) |
| | Igni_0853 | Ser-tRNA(Thr) hydrolase; PFAM: tRNA synthetase, class II (G, H, P and S); Anticodon-binding domain protein. (462 aa) |
| | queC | exsB protein; Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)). Belongs to the QueC family. (260 aa) |
| | hisS | TIGRFAM: histidyl-tRNA synthetase; PFAM: tRNA synthetase, class II (G, H, P and S); Anticodon-binding domain protein; Belongs to the class-II aminoacyl-tRNA synthetase family. (429 aa) |
| | Igni_0891 | Transketolase subunit B; PFAM: Transketolase, central region; Transketolase domain protein. (316 aa) |
| | Igni_0892 | TIGRFAM: chorismate mutase; PFAM: Chorismate mutase; Prephenate dehydrogenase; NADP oxidoreductase, coenzyme F420-dependent; 6-phosphogluconate dehydrogenase, NAD-binding; NAD-dependent glycerol-3-phosphate dehydrogenase domain protein. (348 aa) |
| | purF | Amidophosphoribosyltransferase; Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine. (432 aa) |
| | Igni_0910 | PFAM: Creatininase. (185 aa) |
| | Igni_0925 | PFAM: Anthranilate synthase component I and chorismate binding protein; Anthranilate synthase component I domain protein. (401 aa) |
| | trpF | PFAM: N-(5'phosphoribosyl)anthranilate isomerase (PRAI); Belongs to the TrpF family. (194 aa) |
| | argS | TIGRFAM: arginyl-tRNA synthetase; Belongs to the class-I aminoacyl-tRNA synthetase family. (622 aa) |
| | leuC | 3-isopropylmalate dehydratase, large subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. (419 aa) |
| | Igni_0938 | PFAM: tRNA synthetase class I (M). (845 aa) |
| | lysJ | N2-acetyl-L-lysine aminotransferase; Involved in both the arginine and lysine biosynthetic pathways; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. LysJ subfamily. (386 aa) |
| | Igni_0946 | PFAM: aminotransferase, class V; aromatic amino acid beta-eliminating lyase/threonine aldolase. (376 aa) |
| | ilvD | TIGRFAM: dihydroxy-acid dehydratase; PFAM: dihydroxy-acid and 6-phosphogluconate dehydratase; Belongs to the IlvD/Edd family. (552 aa) |
| | Igni_0976 | Metal-dependent hydrolase of the beta-lactamase superfamily II-like protein. (222 aa) |
| | Igni_0982 | TIGRFAM: isopropylmalate/isohomocitrate dehydrogenase; PFAM: isocitrate/isopropylmalate dehydrogenase. (343 aa) |
| | leuA | Isopropylmalate/citramalate/homocitrate synthase; Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3- hydroxy-4-methylpentanoate (2-isopropylmalate). (399 aa) |
| | Igni_0986 | TIGRFAM: HAD-superfamily hydrolase, subfamily IB (PSPase-like); PFAM: Haloacid dehalogenase domain protein hydrolase. (240 aa) |
| | serS | seryl-tRNA synthetase; Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L- seryl-tRNA(Sec), which will be further converted into selenocysteinyl- tRNA(Sec). (458 aa) |
| | cysS | TIGRFAM: cysteinyl-tRNA synthetase; PFAM: Cysteinyl-tRNA synthetase, class Ia, DALR; tRNA synthetase class I (M); Cysteinyl-tRNA synthetase, class Ia-like. (464 aa) |
| | gap | TIGRFAM: glyceraldehyde-3-phosphate dehydrogenase, type II; PFAM: glyceraldehyde 3-phosphate dehydrogenase; dihydrodipicolinate reductase. (352 aa) |
| | eno | Enolase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family. (414 aa) |
| | Igni_1017 | TIGRFAM: isoleucyl-tRNA synthetase; Belongs to the class-I aminoacyl-tRNA synthetase family. (1025 aa) |
| | Igni_1034 | L-threonine synthase; Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine. (408 aa) |
| | Igni_1041 | TIGRFAM: transcriptional regulator, AbrB family; PFAM: amino acid-binding ACT domain protein; SpoVT/AbrB domain protein. (142 aa) |
| | Igni_1058 | 3-hydroxyacyl-CoA dehydrogenase, NAD-binding; PFAM: Enoyl-CoA hydratase/isomerase; 3-hydroxyacyl-CoA dehydrogenase domain protein; 3-hydroxyacyl-CoA dehydrogenase, NAD-binding; Belongs to the enoyl-CoA hydratase/isomerase family. (683 aa) |
| | Igni_1064 | TIGRFAM: isocitrate dehydrogenase, NADP-dependent; PFAM: isocitrate/isopropylmalate dehydrogenase. (419 aa) |
| | Igni_1076 | 2-oxoglutarate ferredoxin oxidoreductase, gamma subunit; PFAM: pyruvate ferredoxin/flavodoxin oxidoreductase. (175 aa) |
| | Igni_1077 | 2-oxoglutarate ferredoxin oxidoreductase, beta subunit; PFAM: thiamine pyrophosphate enzyme domain protein TPP-binding. (288 aa) |
| | leuC-2 | 3-isopropylmalate dehydratase; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. (429 aa) |
| | glyA | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with a modified folate serving as the one-carbon carrier. Also exhibits a pteridine-independent aldolase activity toward beta- hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. (433 aa) |
| | Igni_1097 | TIGRFAM: acetolactate synthase, large subunit, biosynthetic type; PFAM: thiamine pyrophosphate enzyme domain protein TPP-binding; thiamine pyrophosphate enzyme, central region; thiamine pyrophosphate enzyme TPP binding domain protein. (577 aa) |
| | trpB | Tryptophan synthase, beta chain; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine. (426 aa) |
| | Igni_1101 | PFAM: molybdopterin oxidoreductase. (564 aa) |
| | Igni_1102 | Cystathionine gamma-synthase; PFAM: Cys/Met metabolism pyridoxal-phosphate-dependent enzymes. (387 aa) |
| | mtnP | Methylthioadenosine phosphorylase; Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S-adenosylmethionine. Has broad substrate specificity with 6-aminopurine nucleosides as preferred substrates; Belongs to the PNP/MTAP phosphorylase family. MTAP subfamily. (272 aa) |
| | gltX | glutamyl-tRNA synthetase; Catalyzes the attachment of glutamate to tRNA(Glu) in a two- step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu). (562 aa) |
| | Igni_1113 | Phosphoenolpyruvate synthase; Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate; Belongs to the PEP-utilizing enzyme family. (821 aa) |
