(49 nodes) Protein targeting to ER network (Oryza sativa f. spontanea)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	A0A0E0JCQ5	Plug_translocon domain-containing protein; Belongs to the SecY/SEC61-alpha family. (384 aa)
	A0A0E0G1R8	ULP_PROTEASE domain-containing protein. (941 aa)
	A0A0E0G166	Uncharacterized protein. (366 aa)
	A0A0E0G164	Uncharacterized protein. (172 aa)
	A0A0E0G142	Uncharacterized protein. (359 aa)
	A0A0E0G131	Uncharacterized protein. (564 aa)
	A0A0E0G0W4	Uncharacterized protein. (466 aa)
	A0A0E0G0T9	Uncharacterized protein. (365 aa)
	A0A0E0FZZ0	Uncharacterized protein. (318 aa)
	A0A0E0FZ20	SRP54 domain-containing protein. (379 aa)
	A0A0E0FWS9	Signal recognition particle subunit SRP72; Signal-recognition-particle assembly has a crucial role in targeting secretory proteins to the rough endoplasmic reticulum membrane; Belongs to the SRP72 family. (670 aa)
	A0A0E0FTT1	Signal recognition particle 54 kDa protein; Binds to the signal sequence of presecretory protein when they emerge from the ribosomes and transfers them to TRAM (translocating chain-associating membrane protein). Belongs to the GTP-binding SRP family. SRP54 subfamily. (496 aa)
	A0A0E0HGR9	Signal recognition particle 54 kDa protein; Binds to the signal sequence of presecretory protein when they emerge from the ribosomes and transfers them to TRAM (translocating chain-associating membrane protein). Belongs to the GTP-binding SRP family. SRP54 subfamily. (483 aa)
	A0A0E0HLA3	ArsA_ATPase domain-containing protein. (393 aa)
	A0A0E0HNM9	SRP9-21 domain-containing protein. (217 aa)
	A0A0E0HQF9	Uncharacterized protein. (136 aa)
	A0A0E0HUE4	Uncharacterized protein. (114 aa)
	A0A0E0I6Y2	Uncharacterized protein. (353 aa)
	A0A0E0I9B7	Uncharacterized protein. (587 aa)
	A0A0E0IA90	Uncharacterized protein. (96 aa)
	A0A0E0IDF4	SRP54 domain-containing protein. (624 aa)
	A0A0E0IER8	Uncharacterized protein. (256 aa)
	A0A0E0II21	Uncharacterized protein; Belongs to the SecY/SEC61-alpha family. (741 aa)
	A0A0E0IIX1	Signal recognition particle subunit SRP68; Signal-recognition-particle assembly has a crucial role in targeting secretory proteins to the rough endoplasmic reticulum membrane; Belongs to the SRP68 family. (613 aa)
	A0A0E0IM83	Uncharacterized protein; Belongs to the SecY/SEC61-alpha family. (204 aa)
	A0A0E0IMI6	ATPase; ATPase required for the post-translational delivery of tail- anchored (TA) proteins to the endoplasmic reticulum. Recognizes and selectively binds the transmembrane domain of TA proteins in the cytosol. This complex then targets to the endoplasmic reticulum by membrane-bound receptors, where the tail-anchored protein is released for insertion. This process is regulated by ATP binding and hydrolysis. ATP binding drives the homodimer towards the closed dimer state, facilitating recognition of newly synthesized TA membrane proteins. ATP hydrolysis is required for insertion. Subseq [...] (361 aa)
	A0A0E0INH4	Signal peptidase complex subunit 3; Microsomal signal peptidase is a membrane-bound endoproteinase that removes signal peptides from nascent proteins as they are translocated into the lumen of the endoplasmic reticulum. Belongs to the SPCS3 family. (146 aa)
	A0A0E0IRF5	Uncharacterized protein. (144 aa)
	A0A0E0ITU0	Uncharacterized protein. (118 aa)
	A0A0E0IYF9	Uncharacterized protein. (1221 aa)
	A0A0E0J5P5	Protein transport protein Sec61 subunit beta; Necessary for protein translocation in the endoplasmic reticulum. (107 aa)
	A0A0E0J7D9	Protein transport protein Sec61 subunit beta; Necessary for protein translocation in the endoplasmic reticulum. (83 aa)
	A0A0E0JAI4	Uncharacterized protein; Belongs to the SecY/SEC61-alpha family. (473 aa)
	A0A0E0JBQ8	Protein transport protein Sec61 subunit beta; Necessary for protein translocation in the endoplasmic reticulum. (107 aa)
	A0A0E0JCD0	Uncharacterized protein; Belongs to the SecY/SEC61-alpha family. (433 aa)
	A0A0E0G2G7	Uncharacterized protein. (69 aa)
	A0A0E0FIU7	Plug_translocon domain-containing protein; Belongs to the SecY/SEC61-alpha family. (469 aa)
	A0A0E0FNA2	Protein transport protein Sec61 subunit beta; Necessary for protein translocation in the endoplasmic reticulum. (80 aa)
	A0A0E0HE36	Uncharacterized protein; Belongs to the SecY/SEC61-alpha family. (934 aa)
	A0A0E0H828	TPR_REGION domain-containing protein. (523 aa)
	A0A0E0H366	Uncharacterized protein. (195 aa)
	A0A0E0H1F2	Uncharacterized protein. (172 aa)
	A0A0E0GYV7	J domain-containing protein. (681 aa)
	A0A0E0GY84	Uncharacterized protein. (358 aa)
	A0A0E0GS63	Plug_translocon domain-containing protein. (482 aa)
	A0A0E0GIX5	Plug_translocon domain-containing protein; Belongs to the SecY/SEC61-alpha family. (475 aa)
	A0A0E0G8G2	Uncharacterized protein. (191 aa)
	A0A0E0G841	TPR_REGION domain-containing protein. (535 aa)
	A0A0E0G627	Uncharacterized protein. (372 aa)

Your Current Organism:

Oryza sativa f. spontanea

NCBI taxonomy Id: 4536
Other names: O. sativa f. spontanea, Oryza nivara, Oryza nivara S.D.Sharma & Shastry, Oryza sativa f. spontanea Roshev. nom. illeg.

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Browse interactions in tabular form:

node1	node2	node1 annotation	node2 annotation	score
A0A0E0FIU7	A0A0E0FNA2	Plug_translocon domain-containing protein; Belongs to the SecY/SEC61-alpha family.	Protein transport protein Sec61 subunit beta; Necessary for protein translocation in the endoplasmic reticulum.	0.845
A0A0E0FIU7	A0A0E0FTT1	Plug_translocon domain-containing protein; Belongs to the SecY/SEC61-alpha family.	Signal recognition particle 54 kDa protein; Binds to the signal sequence of presecretory protein when they emerge from the ribosomes and transfers them to TRAM (translocating chain-associating membrane protein). Belongs to the GTP-binding SRP family. SRP54 subfamily.	0.565
A0A0E0FIU7	A0A0E0FZ20	Plug_translocon domain-containing protein; Belongs to the SecY/SEC61-alpha family.	SRP54 domain-containing protein.	0.565
A0A0E0FIU7	A0A0E0G2G7	Plug_translocon domain-containing protein; Belongs to the SecY/SEC61-alpha family.	Uncharacterized protein.	0.753
A0A0E0FIU7	A0A0E0G627	Plug_translocon domain-containing protein; Belongs to the SecY/SEC61-alpha family.	Uncharacterized protein.	0.705
A0A0E0FIU7	A0A0E0GYV7	Plug_translocon domain-containing protein; Belongs to the SecY/SEC61-alpha family.	J domain-containing protein.	0.848
A0A0E0FIU7	A0A0E0H366	Plug_translocon domain-containing protein; Belongs to the SecY/SEC61-alpha family.	Uncharacterized protein.	0.453
A0A0E0FIU7	A0A0E0HGR9	Plug_translocon domain-containing protein; Belongs to the SecY/SEC61-alpha family.	Signal recognition particle 54 kDa protein; Binds to the signal sequence of presecretory protein when they emerge from the ribosomes and transfers them to TRAM (translocating chain-associating membrane protein). Belongs to the GTP-binding SRP family. SRP54 subfamily.	0.565
A0A0E0FIU7	A0A0E0HQF9	Plug_translocon domain-containing protein; Belongs to the SecY/SEC61-alpha family.	Uncharacterized protein.	0.420
A0A0E0FIU7	A0A0E0HUE4	Plug_translocon domain-containing protein; Belongs to the SecY/SEC61-alpha family.	Uncharacterized protein.	0.753
A0A0E0FIU7	A0A0E0I9B7	Plug_translocon domain-containing protein; Belongs to the SecY/SEC61-alpha family.	Uncharacterized protein.	0.898
A0A0E0FIU7	A0A0E0IDF4	Plug_translocon domain-containing protein; Belongs to the SecY/SEC61-alpha family.	SRP54 domain-containing protein.	0.857
A0A0E0FIU7	A0A0E0IER8	Plug_translocon domain-containing protein; Belongs to the SecY/SEC61-alpha family.	Uncharacterized protein.	0.453
A0A0E0FIU7	A0A0E0ITU0	Plug_translocon domain-containing protein; Belongs to the SecY/SEC61-alpha family.	Uncharacterized protein.	0.753
A0A0E0FIU7	A0A0E0IYF9	Plug_translocon domain-containing protein; Belongs to the SecY/SEC61-alpha family.	Uncharacterized protein.	0.565
A0A0E0FIU7	A0A0E0J5P5	Plug_translocon domain-containing protein; Belongs to the SecY/SEC61-alpha family.	Protein transport protein Sec61 subunit beta; Necessary for protein translocation in the endoplasmic reticulum.	0.859
A0A0E0FIU7	A0A0E0J7D9	Plug_translocon domain-containing protein; Belongs to the SecY/SEC61-alpha family.	Protein transport protein Sec61 subunit beta; Necessary for protein translocation in the endoplasmic reticulum.	0.845
A0A0E0FIU7	A0A0E0JBQ8	Plug_translocon domain-containing protein; Belongs to the SecY/SEC61-alpha family.	Protein transport protein Sec61 subunit beta; Necessary for protein translocation in the endoplasmic reticulum.	0.859
A0A0E0FNA2	A0A0E0FIU7	Protein transport protein Sec61 subunit beta; Necessary for protein translocation in the endoplasmic reticulum.	Plug_translocon domain-containing protein; Belongs to the SecY/SEC61-alpha family.	0.845
A0A0E0FNA2	A0A0E0FTT1	Protein transport protein Sec61 subunit beta; Necessary for protein translocation in the endoplasmic reticulum.	Signal recognition particle 54 kDa protein; Binds to the signal sequence of presecretory protein when they emerge from the ribosomes and transfers them to TRAM (translocating chain-associating membrane protein). Belongs to the GTP-binding SRP family. SRP54 subfamily.	0.511