(8 nodes) Mixed, incl. Structural constituent of chromatin, and NAP-like superfamily network (Aspergillus calidoustus)

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	ASPCAL05492	SHNi-TPR domain-containing protein. (444 aa)
	ASPCAL12683	Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. (103 aa)
	ASPCAL03030	DUF2236 domain-containing protein. (459 aa)
	ASPCAL00334	Histone acetyltransferase type B catalytic subunit; Catalytic component of the histone acetylase B (HAT-B) complex. Has intrinsic substrate specificity that modifies lysine in recognition sequence GXGKXG. Involved in DNA double-strand break repair; Belongs to the HAT1 family. (494 aa)
	ASPCAL05387	Histone acetyltransferase. (512 aa)
	ASPCAL12684	Histone H3; Belongs to the histone H3 family. (136 aa)
	ASPCAL02787	Uncharacterized protein; Belongs to the nucleosome assembly protein (NAP) family. (348 aa)
	ASPCAL02735	Putative Histone acetyltransferase type B subunit 2. (436 aa)

Your Current Organism:

Aspergillus calidoustus

NCBI taxonomy Id: 454130
Other names: A. calidoustus, Aspergillus calidoustus Varga, Houbraken & Samson 2008, Aspergillus sp. JV-2007c, CBS 121601

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ASPCAL00334	ASPCAL02735	A0A0U5FMQ0	A0A0U5GR35	Histone acetyltransferase type B catalytic subunit; Catalytic component of the histone acetylase B (HAT-B) complex. Has intrinsic substrate specificity that modifies lysine in recognition sequence GXGKXG. Involved in DNA double-strand break repair; Belongs to the HAT1 family.	Putative Histone acetyltransferase type B subunit 2.	0.999
ASPCAL00334	ASPCAL03030	A0A0U5FMQ0	A0A0U5CNR9	Histone acetyltransferase type B catalytic subunit; Catalytic component of the histone acetylase B (HAT-B) complex. Has intrinsic substrate specificity that modifies lysine in recognition sequence GXGKXG. Involved in DNA double-strand break repair; Belongs to the HAT1 family.	DUF2236 domain-containing protein.	0.860
ASPCAL00334	ASPCAL05387	A0A0U5FMQ0	A0A0U5FXH2	Histone acetyltransferase type B catalytic subunit; Catalytic component of the histone acetylase B (HAT-B) complex. Has intrinsic substrate specificity that modifies lysine in recognition sequence GXGKXG. Involved in DNA double-strand break repair; Belongs to the HAT1 family.	Histone acetyltransferase.	0.487
ASPCAL00334	ASPCAL05492	A0A0U5FMQ0	A0A0U5C6Z1	Histone acetyltransferase type B catalytic subunit; Catalytic component of the histone acetylase B (HAT-B) complex. Has intrinsic substrate specificity that modifies lysine in recognition sequence GXGKXG. Involved in DNA double-strand break repair; Belongs to the HAT1 family.	SHNi-TPR domain-containing protein.	0.981
ASPCAL00334	ASPCAL12683	A0A0U5FMQ0	A0A0U5CGC0	Histone acetyltransferase type B catalytic subunit; Catalytic component of the histone acetylase B (HAT-B) complex. Has intrinsic substrate specificity that modifies lysine in recognition sequence GXGKXG. Involved in DNA double-strand break repair; Belongs to the HAT1 family.	Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.	0.971
ASPCAL00334	ASPCAL12684	A0A0U5FMQ0	A0A0U5GEQ9	Histone acetyltransferase type B catalytic subunit; Catalytic component of the histone acetylase B (HAT-B) complex. Has intrinsic substrate specificity that modifies lysine in recognition sequence GXGKXG. Involved in DNA double-strand break repair; Belongs to the HAT1 family.	Histone H3; Belongs to the histone H3 family.	0.963
ASPCAL02735	ASPCAL00334	A0A0U5GR35	A0A0U5FMQ0	Putative Histone acetyltransferase type B subunit 2.	Histone acetyltransferase type B catalytic subunit; Catalytic component of the histone acetylase B (HAT-B) complex. Has intrinsic substrate specificity that modifies lysine in recognition sequence GXGKXG. Involved in DNA double-strand break repair; Belongs to the HAT1 family.	0.999
ASPCAL02735	ASPCAL02787	A0A0U5GR35	A0A0U5GLI0	Putative Histone acetyltransferase type B subunit 2.	Uncharacterized protein; Belongs to the nucleosome assembly protein (NAP) family.	0.661
ASPCAL02735	ASPCAL03030	A0A0U5GR35	A0A0U5CNR9	Putative Histone acetyltransferase type B subunit 2.	DUF2236 domain-containing protein.	0.886
ASPCAL02735	ASPCAL05492	A0A0U5GR35	A0A0U5C6Z1	Putative Histone acetyltransferase type B subunit 2.	SHNi-TPR domain-containing protein.	0.966
ASPCAL02735	ASPCAL12683	A0A0U5GR35	A0A0U5CGC0	Putative Histone acetyltransferase type B subunit 2.	Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.	0.972
ASPCAL02735	ASPCAL12684	A0A0U5GR35	A0A0U5GEQ9	Putative Histone acetyltransferase type B subunit 2.	Histone H3; Belongs to the histone H3 family.	0.969
ASPCAL02787	ASPCAL02735	A0A0U5GLI0	A0A0U5GR35	Uncharacterized protein; Belongs to the nucleosome assembly protein (NAP) family.	Putative Histone acetyltransferase type B subunit 2.	0.661
ASPCAL02787	ASPCAL03030	A0A0U5GLI0	A0A0U5CNR9	Uncharacterized protein; Belongs to the nucleosome assembly protein (NAP) family.	DUF2236 domain-containing protein.	0.688
ASPCAL02787	ASPCAL05387	A0A0U5GLI0	A0A0U5FXH2	Uncharacterized protein; Belongs to the nucleosome assembly protein (NAP) family.	Histone acetyltransferase.	0.966
ASPCAL02787	ASPCAL12683	A0A0U5GLI0	A0A0U5CGC0	Uncharacterized protein; Belongs to the nucleosome assembly protein (NAP) family.	Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.	0.803
ASPCAL02787	ASPCAL12684	A0A0U5GLI0	A0A0U5GEQ9	Uncharacterized protein; Belongs to the nucleosome assembly protein (NAP) family.	Histone H3; Belongs to the histone H3 family.	0.825
ASPCAL03030	ASPCAL00334	A0A0U5CNR9	A0A0U5FMQ0	DUF2236 domain-containing protein.	Histone acetyltransferase type B catalytic subunit; Catalytic component of the histone acetylase B (HAT-B) complex. Has intrinsic substrate specificity that modifies lysine in recognition sequence GXGKXG. Involved in DNA double-strand break repair; Belongs to the HAT1 family.	0.860
ASPCAL03030	ASPCAL02735	A0A0U5CNR9	A0A0U5GR35	DUF2236 domain-containing protein.	Putative Histone acetyltransferase type B subunit 2.	0.886
ASPCAL03030	ASPCAL02787	A0A0U5CNR9	A0A0U5GLI0	DUF2236 domain-containing protein.	Uncharacterized protein; Belongs to the nucleosome assembly protein (NAP) family.	0.688