STRINGSTRING
purQ purQ carA carA CDM64196.1 CDM64196.1 carB carB glmS glmS CDM64600.1 CDM64600.1 purF purF CDM64648.1 CDM64648.1 CDM64928.1 CDM64928.1 CDM65097.1 CDM65097.1 CDM65121.1 CDM65121.1 CDM65183.1 CDM65183.1 CDM65244.1 CDM65244.1 CDM65459.1 CDM65459.1 argH argH argG argG purA purA CDM65688.1 CDM65688.1 CDM65932.1 CDM65932.1 pyrB pyrB CDM66249.1 CDM66249.1 CDM66253.1 CDM66253.1 CDM66254.1 CDM66254.1 CDM66582.1 CDM66582.1 CDM66702.1 CDM66702.1 CDM66738.1 CDM66738.1 argH-2 argH-2 CDM66840.1 CDM66840.1 CDM66988.1 CDM66988.1 CDM67035.1 CDM67035.1 CDM67109.1 CDM67109.1 CDM67091.1 CDM67091.1
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Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
Your Input:
purQPhosphoribosylformylglycinamidine synthase subunit I; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought to [...] (234 aa)
carAPFAM: Carbamoyl-phosphate synthase small chain, CPSase domain; Glutamine amidotransferase class-I; TIGRFAM: carbamoyl-phosphate synthase, small subunit; Belongs to the CarA family. (380 aa)
CDM64196.1L-alanine aminotransferase apoenzyme; PFAM: Aminotransferase class I and II. (439 aa)
carBPFAM: Carbamoyl-phosphate synthase L chain, ATP binding domain; MGS-like domain; Carbamoyl-phosphate synthetase large chain, oligomerisation domain; Carbamoyl-phosphate synthase L chain, N-terminal domain; TIGRFAM: carbamoyl-phosphate synthase, large subunit; Belongs to the CarB family. (1075 aa)
glmSGlutamine--fructose-6-phosphate transaminase; Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source. (619 aa)
CDM64600.1Glutamine--fructose-6-phosphate transaminase; PFAM: SIS domain. (342 aa)
purFAmidophosphoribosyltransferase; Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine. (474 aa)
CDM64648.1PFAM: Alanine dehydrogenase/PNT, C-terminal domain; Alanine dehydrogenase/PNT, N-terminal domain; TIGRFAM: alanine dehydrogenase; Belongs to the AlaDH/PNT family. (374 aa)
CDM64928.1PFAM: Aldehyde dehydrogenase family; TIGRFAM: delta-1-pyrroline-5-carboxylate dehydrogenase, group 2, putative; Belongs to the aldehyde dehydrogenase family. (518 aa)
CDM65097.1Asparagine synthase, glutamine-hydrolyzing; PFAM: Glutamine amidotransferase domain; Asparagine synthase; TIGRFAM: asparagine synthase (glutamine-hydrolyzing). (627 aa)
CDM65121.1PFAM: Glutamine synthetase, catalytic domain; Glutamine synthetase, beta-Grasp domain; TIGRFAM: glutamine synthetase, type I. (474 aa)
CDM65183.1Asparagine synthase, glutamine-hydrolyzing; PFAM: Glutamine amidotransferase domain; Asparagine synthase; TIGRFAM: asparagine synthase (glutamine-hydrolyzing). (592 aa)
CDM65244.1PFAM: Aminotransferase class I and II. (401 aa)
CDM65459.1PFAM: Glutamate/Leucine/Phenylalanine/Valine dehydrogenase; Glu/Leu/Phe/Val dehydrogenase, dimerisation domain; Belongs to the Glu/Leu/Phe/Val dehydrogenases family. (426 aa)
argHPFAM: Lyase; Argininosuccinate lyase C-terminal; TIGRFAM: argininosuccinate lyase. (459 aa)
argGPFAM: Arginosuccinate synthase; TIGRFAM: argininosuccinate synthase; Belongs to the argininosuccinate synthase family. Type 1 subfamily. (400 aa)
purAAdenylosuccinate synthetase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family. (449 aa)
CDM65688.1PFAM: Aldehyde dehydrogenase family. (463 aa)
CDM65932.1Glycosylasparaginase precursor; PFAM: Asparaginase. (408 aa)
pyrBPFAM: Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain; Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain; TIGRFAM: aspartate carbamoyltransferase; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family. (338 aa)
CDM66249.1Asparagine synthase, glutamine-hydrolyzing; PFAM: Glutamine amidotransferase domain; Asparagine synthase; TIGRFAM: asparagine synthase (glutamine-hydrolyzing). (648 aa)
CDM66253.1Asparagine synthase, glutamine-hydrolyzing; PFAM: Glutamine amidotransferase domain; Asparagine synthase; TIGRFAM: asparagine synthase (glutamine-hydrolyzing). (638 aa)
CDM66254.1Asparagine synthase, glutamine-hydrolyzing; PFAM: Glutamine amidotransferase domain; Asparagine synthase; TIGRFAM: asparagine synthase (glutamine-hydrolyzing); exosortase A system-associated amidotransferase 1. (645 aa)
CDM66582.1Asparagine synthase, glutamine-hydrolyzing; PFAM: Glutamine amidotransferase domain; Asparagine synthase; TIGRFAM: asparagine synthase (glutamine-hydrolyzing). (645 aa)
CDM66702.1PFAM: Aminotransferase class I and II. (390 aa)
CDM66738.1PFAM: Aminotransferase class-III; TIGRFAM: 4-aminobutyrate aminotransferase, prokaryotic type; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (453 aa)
argH-2PFAM: Lyase; Argininosuccinate lyase C-terminal; TIGRFAM: argininosuccinate lyase. (506 aa)
CDM66840.1PFAM: L-asparaginase II. (366 aa)
CDM66988.1PFAM: Aldehyde dehydrogenase family; Belongs to the aldehyde dehydrogenase family. (529 aa)
CDM67035.1Glutamate synthase (NADH) small subunit; PFAM: Pyridine nucleotide-disulphide oxidoreductase; Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster; TIGRFAM: glutamate synthases, NADH/NADPH, small subunit. (498 aa)
CDM67109.1PFAM: Lyase; Adenylosuccinate lyase C-terminus; TIGRFAM: adenylosuccinate lyase; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. (431 aa)
CDM67091.1L-aspartate oxidase; Catalyzes the oxidation of L-aspartate to iminoaspartate. (526 aa)
Your Current Organism:
Pyrinomonas methylaliphatogenes
NCBI taxonomy Id: 454194
Other names: Acidobacteriaceae bacterium K22, DSM 25857, ICMP 18710, P. methylaliphatogenes, Pyrinomonas methylaliphatogenes Crowe et al. 2014, strain K22
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