(30 nodes) Transcription factor TFIIH holo complex, and Transcription factor TFIIE complex network (Setaria italica)

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

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second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

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Your Input:
	A0A368QJ06	Protein kinase domain-containing protein. (175 aa)
	A0A368QJA0	Uncharacterized protein. (70 aa)
	A0A368QK57	Uncharacterized protein. (387 aa)
	A0A368R9Q8	Uncharacterized protein. (721 aa)
	A0A368RIP7	Uncharacterized protein. (599 aa)
	A0A368SX44	TFIIE beta domain-containing protein. (225 aa)
	K3XPD2_SETIT	Uncharacterized protein. (222 aa)
	K3XYP7_SETIT	Transcription initiation factor IIE subunit beta; Recruits TFIIH to the initiation complex and stimulates the RNA polymerase II C-terminal domain kinase and DNA-dependent ATPase activities of TFIIH. Both TFIIH and TFIIE are required for promoter clearance by RNA polymerase. (279 aa)
	K3XYQ0_SETIT	Transcription initiation factor IIE subunit beta; Recruits TFIIH to the initiation complex and stimulates the RNA polymerase II C-terminal domain kinase and DNA-dependent ATPase activities of TFIIH. Both TFIIH and TFIIE are required for promoter clearance by RNA polymerase. (278 aa)
	K3XZG6_SETIT	MAT1 domain-containing protein. (194 aa)
	K3Y4Z0_SETIT	Uncharacterized protein. (957 aa)
	K3Y5E6_SETIT	Uncharacterized protein. (765 aa)
	K3Y7G5_SETIT	General transcription factor IIH subunit. (432 aa)
	K3YGS8_SETIT	Uncharacterized protein. (600 aa)
	K3YHK5_SETIT	RNA polymerase II transcription factor B subunit 2; Component of the general transcription and DNA repair factor IIH (TFIIH) core complex which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA. Belongs to the TFB2 family. (451 aa)
	K3YSE8_SETIT	HTH TFE/IIEalpha-type domain-containing protein. (449 aa)
	K3YUM7_SETIT	Uncharacterized protein. (291 aa)
	K3YWX7_SETIT	Transcription initiation factor IIA subunit 2; TFIIA is a component of the transcription machinery of RNA polymerase II and plays an important role in transcriptional activation; Belongs to the TFIIA subunit 2 family. (109 aa)
	K3Z428_SETIT	Helicase ATP-binding domain-containing protein. (758 aa)
	K3Z5G1_SETIT	Uncharacterized protein. (515 aa)
	K3Z6H1_SETIT	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (424 aa)
	K3ZB01_SETIT	Transcription initiation factor IIA subunit 2; TFIIA is a component of the transcription machinery of RNA polymerase II and plays an important role in transcriptional activation; Belongs to the TFIIA subunit 2 family. (106 aa)
	K3ZBI0_SETIT	Uncharacterized protein. (70 aa)
	K3ZD32_SETIT	RNA polymerase II transcription factor B subunit 2; Component of the general transcription and DNA repair factor IIH (TFIIH) core complex which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA. Belongs to the TFB2 family. (114 aa)
	K3ZDD2_SETIT	TFIIB domain-containing protein. (272 aa)
	K3ZFV6_SETIT	RNA polymerase II transcription factor B subunit 2; Component of the general transcription and DNA repair factor IIH (TFIIH) core complex which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA. Belongs to the TFB2 family. (94 aa)
	K4A6J5_SETIT	Transcription initiation factor IIF subunit alpha; TFIIF is a general transcription initiation factor that binds to RNA polymerase II and helps to recruit it to the initiation complex in collaboration with TFIIB. It promotes transcription elongation. Belongs to the TFIIF alpha subunit family. (692 aa)
	K4A9M3_SETIT	HTH TFE/IIEalpha-type domain-containing protein. (463 aa)
	K4AIY6_SETIT	CYCLIN domain-containing protein; Belongs to the cyclin family. (326 aa)
	K4AJ03_SETIT	Transcription initiation factor IIE subunit beta; Recruits TFIIH to the initiation complex and stimulates the RNA polymerase II C-terminal domain kinase and DNA-dependent ATPase activities of TFIIH. Both TFIIH and TFIIE are required for promoter clearance by RNA polymerase. (277 aa)

Your Current Organism:

Setaria italica

NCBI taxonomy Id: 4555
Other names: Chaetochloa italica, Chaetochloa italica (L.) Scribn., Panicum italicum, Panicum italicum L., S. italica, Setaria italica (L.) P.Beauv., Setaria viridis subsp. italica, Setaria viridis subsp. italica (L.) Briq., foxtail millet

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
A0A368QJ06	A0A368QJA0	A0A368QJ06	A0A368QJA0	Protein kinase domain-containing protein.	Uncharacterized protein.	0.852
A0A368QJ06	A0A368QK57	A0A368QJ06	A0A368QK57	Protein kinase domain-containing protein.	Uncharacterized protein.	0.855
A0A368QJ06	A0A368R9Q8	A0A368QJ06	A0A368R9Q8	Protein kinase domain-containing protein.	Uncharacterized protein.	0.952
A0A368QJ06	A0A368RIP7	A0A368QJ06	A0A368RIP7	Protein kinase domain-containing protein.	Uncharacterized protein.	0.978
A0A368QJ06	A0A368SX44	A0A368QJ06	A0A368SX44	Protein kinase domain-containing protein.	TFIIE beta domain-containing protein.	0.933
A0A368QJ06	K3XPD2_SETIT	A0A368QJ06	K3XPD2	Protein kinase domain-containing protein.	Uncharacterized protein.	0.746
A0A368QJ06	K3XYP7_SETIT	A0A368QJ06	K3XYP7	Protein kinase domain-containing protein.	Transcription initiation factor IIE subunit beta; Recruits TFIIH to the initiation complex and stimulates the RNA polymerase II C-terminal domain kinase and DNA-dependent ATPase activities of TFIIH. Both TFIIH and TFIIE are required for promoter clearance by RNA polymerase.	0.933
A0A368QJ06	K3XYQ0_SETIT	A0A368QJ06	K3XYQ0	Protein kinase domain-containing protein.	Transcription initiation factor IIE subunit beta; Recruits TFIIH to the initiation complex and stimulates the RNA polymerase II C-terminal domain kinase and DNA-dependent ATPase activities of TFIIH. Both TFIIH and TFIIE are required for promoter clearance by RNA polymerase.	0.933
A0A368QJ06	K3XZG6_SETIT	A0A368QJ06	K3XZG6	Protein kinase domain-containing protein.	MAT1 domain-containing protein.	0.990
A0A368QJ06	K3Y4Z0_SETIT	A0A368QJ06	K3Y4Z0	Protein kinase domain-containing protein.	Uncharacterized protein.	0.992
A0A368QJ06	K3Y5E6_SETIT	A0A368QJ06	K3Y5E6	Protein kinase domain-containing protein.	Uncharacterized protein.	0.952
A0A368QJ06	K3Y7G5_SETIT	A0A368QJ06	K3Y7G5	Protein kinase domain-containing protein.	General transcription factor IIH subunit.	0.993
A0A368QJ06	K3YGS8_SETIT	A0A368QJ06	K3YGS8	Protein kinase domain-containing protein.	Uncharacterized protein.	0.978
A0A368QJ06	K3YHK5_SETIT	A0A368QJ06	K3YHK5	Protein kinase domain-containing protein.	RNA polymerase II transcription factor B subunit 2; Component of the general transcription and DNA repair factor IIH (TFIIH) core complex which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA. Belongs to the TFB2 family.	0.972
A0A368QJ06	K3YSE8_SETIT	A0A368QJ06	K3YSE8	Protein kinase domain-containing protein.	HTH TFE/IIEalpha-type domain-containing protein.	0.973
A0A368QJ06	K3YUM7_SETIT	A0A368QJ06	K3YUM7	Protein kinase domain-containing protein.	Uncharacterized protein.	0.994
A0A368QJ06	K3YWX7_SETIT	A0A368QJ06	K3YWX7	Protein kinase domain-containing protein.	Transcription initiation factor IIA subunit 2; TFIIA is a component of the transcription machinery of RNA polymerase II and plays an important role in transcriptional activation; Belongs to the TFIIA subunit 2 family.	0.889
A0A368QJ06	K3Z428_SETIT	A0A368QJ06	K3Z428	Protein kinase domain-containing protein.	Helicase ATP-binding domain-containing protein.	0.988
A0A368QJ06	K3Z5G1_SETIT	A0A368QJ06	K3Z5G1	Protein kinase domain-containing protein.	Uncharacterized protein.	0.855
A0A368QJ06	K3Z6H1_SETIT	A0A368QJ06	K3Z6H1	Protein kinase domain-containing protein.	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.	0.543

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