(30 nodes) U2-type prespliceosome network (Setaria italica)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	A0A368RL61	Uncharacterized protein. (1176 aa)
	A0A368RPX5	Uncharacterized protein. (147 aa)
	A0A368SC34	Uncharacterized protein. (501 aa)
	A0A368SCB1	Uncharacterized protein. (87 aa)
	A0A368SET0	DUF3700 domain-containing protein. (254 aa)
	A0A368SK56	RRM domain-containing protein. (442 aa)
	A0A368SVP4	Uncharacterized protein. (111 aa)
	A0A368SW01	Uncharacterized protein. (949 aa)
	K3XEN9_SETIT	Uncharacterized protein. (796 aa)
	K3YG19_SETIT	Uncharacterized protein. (1005 aa)
	K3YLI7_SETIT	Uncharacterized protein. (146 aa)
	K3YPC2_SETIT	TOG domain-containing protein. (1278 aa)
	K3YSW3_SETIT	Uncharacterized protein. (413 aa)
	K3YVG8_SETIT	U1 small nuclear ribonucleoprotein C; Component of the spliceosomal U1 snRNP, which is essential for recognition of the pre-mRNA 5' splice-site and the subsequent assembly of the spliceosome. U1-C is directly involved in initial 5' splice-site recognition for both constitutive and regulated alternative splicing. The interaction with the 5' splice-site seems to precede base-pairing between the pre-mRNA and the U1 snRNA. Stimulates commitment or early (E) complex formation by stabilizing the base pairing of the 5' end of the U1 snRNA and the 5' splice-site region. (230 aa)
	K3ZHU0_SETIT	U2 snRNP auxiliary factor large subunit; Necessary for the splicing of pre-mRNA. Belongs to the splicing factor SR family. (595 aa)
	K3ZI03_SETIT	U2 snRNP auxiliary factor large subunit; Necessary for the splicing of pre-mRNA. Belongs to the splicing factor SR family. (530 aa)
	K3ZQD8_SETIT	Uncharacterized protein. (983 aa)
	K3ZUP5_SETIT	Uncharacterized protein. (352 aa)
	K3ZW48_SETIT	Small nuclear ribonucleoprotein-associated protein. (264 aa)
	K3ZYM4_SETIT	Small nuclear ribonucleoprotein G. (81 aa)
	K4A5D5_SETIT	Uncharacterized protein. (973 aa)
	K4A635_SETIT	Uncharacterized protein. (771 aa)
	K4A7M1_SETIT	Uncharacterized protein. (578 aa)
	K4A913_SETIT	Uncharacterized protein. (493 aa)
	K4A925_SETIT	RRM domain-containing protein. (491 aa)
	K4AA44_SETIT	RRM domain-containing protein. (439 aa)
	K4ACP9_SETIT	Matrin-type domain-containing protein. (321 aa)
	K4ADA0_SETIT	DUF3700 domain-containing protein. (294 aa)
	K4AHG4_SETIT	Small nuclear ribonucleoprotein G. (80 aa)
	K4AKB2_SETIT	Uncharacterized protein. (102 aa)

Your Current Organism:

Setaria italica

NCBI taxonomy Id: 4555
Other names: Chaetochloa italica, Chaetochloa italica (L.) Scribn., Panicum italicum, Panicum italicum L., S. italica, Setaria italica (L.) P.Beauv., Setaria viridis subsp. italica, Setaria viridis subsp. italica (L.) Briq., foxtail millet

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
A0A368RL61	A0A368SC34	A0A368RL61	A0A368SC34	Uncharacterized protein.	Uncharacterized protein.	0.865
A0A368RL61	A0A368SCB1	A0A368RL61	A0A368SCB1	Uncharacterized protein.	Uncharacterized protein.	0.865
A0A368RL61	A0A368SK56	A0A368RL61	A0A368SK56	Uncharacterized protein.	RRM domain-containing protein.	0.851
A0A368RL61	A0A368SVP4	A0A368RL61	A0A368SVP4	Uncharacterized protein.	Uncharacterized protein.	0.566
A0A368RL61	K3XEN9_SETIT	A0A368RL61	K3XEN9	Uncharacterized protein.	Uncharacterized protein.	0.707
A0A368RL61	K3YPC2_SETIT	A0A368RL61	K3YPC2	Uncharacterized protein.	TOG domain-containing protein.	0.940
A0A368RL61	K3YSW3_SETIT	A0A368RL61	K3YSW3	Uncharacterized protein.	Uncharacterized protein.	0.865
A0A368RL61	K3YVG8_SETIT	A0A368RL61	K3YVG8	Uncharacterized protein.	U1 small nuclear ribonucleoprotein C; Component of the spliceosomal U1 snRNP, which is essential for recognition of the pre-mRNA 5' splice-site and the subsequent assembly of the spliceosome. U1-C is directly involved in initial 5' splice-site recognition for both constitutive and regulated alternative splicing. The interaction with the 5' splice-site seems to precede base-pairing between the pre-mRNA and the U1 snRNA. Stimulates commitment or early (E) complex formation by stabilizing the base pairing of the 5' end of the U1 snRNA and the 5' splice-site region.	0.943
A0A368RL61	K3ZI03_SETIT	A0A368RL61	K3ZI03	Uncharacterized protein.	U2 snRNP auxiliary factor large subunit; Necessary for the splicing of pre-mRNA. Belongs to the splicing factor SR family.	0.657
A0A368RL61	K3ZQD8_SETIT	A0A368RL61	K3ZQD8	Uncharacterized protein.	Uncharacterized protein.	0.877
A0A368RL61	K3ZUP5_SETIT	A0A368RL61	K3ZUP5	Uncharacterized protein.	Uncharacterized protein.	0.865
A0A368RL61	K3ZW48_SETIT	A0A368RL61	K3ZW48	Uncharacterized protein.	Small nuclear ribonucleoprotein-associated protein.	0.936
A0A368RL61	K3ZYM4_SETIT	A0A368RL61	K3ZYM4	Uncharacterized protein.	Small nuclear ribonucleoprotein G.	0.804
A0A368RL61	K4A5D5_SETIT	A0A368RL61	K4A5D5	Uncharacterized protein.	Uncharacterized protein.	0.642
A0A368RL61	K4A635_SETIT	A0A368RL61	K4A635	Uncharacterized protein.	Uncharacterized protein.	0.583
A0A368RL61	K4A913_SETIT	A0A368RL61	K4A913	Uncharacterized protein.	Uncharacterized protein.	0.812
A0A368RL61	K4A925_SETIT	A0A368RL61	K4A925	Uncharacterized protein.	RRM domain-containing protein.	0.851
A0A368RL61	K4AA44_SETIT	A0A368RL61	K4AA44	Uncharacterized protein.	RRM domain-containing protein.	0.690
A0A368RL61	K4ACP9_SETIT	A0A368RL61	K4ACP9	Uncharacterized protein.	Matrin-type domain-containing protein.	0.845
A0A368RL61	K4AHG4_SETIT	A0A368RL61	K4AHG4	Uncharacterized protein.	Small nuclear ribonucleoprotein G.	0.804

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