(30 nodes) Base excision repair, and Double-strand break repair via nonhomologous end joining network (Sorghum bicolor)

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Your Input:
	SORBI_3K044300	Poly [ADP-ribose] polymerase. (157 aa)
	A0A194YIA1	DNA polymerase; DNA polymerase that functions in several pathways of DNA repair. Involved in base excision repair (BER) responsible for repair of lesions that give rise to abasic (AP) sites in DNA. Also contributes to DNA double-strand break repair by non-homologous end joining and homologous recombination. Has both template-dependent and template- independent (terminal transferase) DNA polymerase activities. Has also a 5'-deoxyribose-5-phosphate lyase (dRP lyase) activity. (552 aa)
	A0A194YQ61	Poly [ADP-ribose] polymerase. (834 aa)
	A0A1B6PP12	Uracil-DNA glycosylase; Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine. (304 aa)
	A0A1B6Q5I4	DNA ligase. (1401 aa)
	A0A1B6Q6M5	SAP domain-containing protein. (803 aa)
	A0A1B6QAL7	Poly [ADP-ribose] polymerase. (979 aa)
	A0A1B6QCQ5	SAM domain-containing protein. (948 aa)
	A0A1B6QGN0	ATP-dependent DNA helicase 2 subunit KU80; Single-stranded DNA-dependent ATP-dependent helicase. (687 aa)
	A0A1B6QNS7	Macro domain-containing protein. (788 aa)
	A0A1W0VZC1	Uncharacterized protein. (633 aa)
	A0A1W0W0P3	53EXOc domain-containing protein. (350 aa)
	NTH1	Endonuclease III homolog; Bifunctional DNA N-glycosylase with associated apurinic/apyrimidinic (AP) lyase function that catalyzes the first step in base excision repair (BER), the primary repair pathway for the repair of oxidative DNA damage. The DNA N-glycosylase activity releases the damaged DNA base from DNA by cleaving the N-glycosidic bond, leaving an AP site. The AP lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination. Primarily recognizes and repairs oxidative base damage of pyrimidines. (374 aa)
	A0A1Z5R6E2	Adenine DNA glycosylase; Adenine glycosylase active on G-A mispairs. (375 aa)
	A0A1Z5REU4	DNA ligase. (1281 aa)
	C5WSZ7_SORBI	Uncharacterized protein. (517 aa)
	C5X199_SORBI	Uncharacterized protein. (283 aa)
	C5X1A7_SORBI	Uncharacterized protein. (90 aa)
	C5X6U3_SORBI	Uncharacterized protein. (618 aa)
	C5X745_SORBI	SAP domain-containing protein. (628 aa)
	C5XB55_SORBI	SAP domain-containing protein. (628 aa)
	C5XJW6_SORBI	Poly [ADP-ribose] polymerase. (658 aa)
	C5XJX0_SORBI	Poly [ADP-ribose] polymerase. (496 aa)
	C5XTJ3_SORBI	Uncharacterized protein. (263 aa)
	C5XU78_SORBI	ENDO3c domain-containing protein. (413 aa)
	C5YMZ3_SORBI	DNA-(apurinic or apyrimidinic site) lyase; Belongs to the DNA repair enzymes AP/ExoA family. (369 aa)
	C5YVX2_SORBI	ENDO3c domain-containing protein. (293 aa)
	C5YWE3_SORBI	ENDO3c domain-containing protein. (338 aa)
	C5Z3V7_SORBI	BRCT domain-containing protein. (346 aa)
	C5Z7C3_SORBI	Uncharacterized protein. (268 aa)

Your Current Organism:

Sorghum bicolor

NCBI taxonomy Id: 4558
Other names: Andropogon sorghum, Andropogon sorghum (L.) Brot., S. bicolor, Sorghum bicolor (L.) Moench, Sorghum bicolor subsp. bicolor, Sorghum nervosum, Sorghum nervosum Besser ex Schult., Sorghum saccharatum, Sorghum saccharatum (L.) Moench, Sorghum vulgare, Sorghum vulgare Pers., broomcorn, milo, sorghum

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
A0A194YIA1	A0A194YQ61	A0A194YIA1	A0A194YQ61	DNA polymerase; DNA polymerase that functions in several pathways of DNA repair. Involved in base excision repair (BER) responsible for repair of lesions that give rise to abasic (AP) sites in DNA. Also contributes to DNA double-strand break repair by non-homologous end joining and homologous recombination. Has both template-dependent and template- independent (terminal transferase) DNA polymerase activities. Has also a 5'-deoxyribose-5-phosphate lyase (dRP lyase) activity.	Poly [ADP-ribose] polymerase.	0.617
A0A194YIA1	A0A1B6PP12	A0A194YIA1	A0A1B6PP12	DNA polymerase; DNA polymerase that functions in several pathways of DNA repair. Involved in base excision repair (BER) responsible for repair of lesions that give rise to abasic (AP) sites in DNA. Also contributes to DNA double-strand break repair by non-homologous end joining and homologous recombination. Has both template-dependent and template- independent (terminal transferase) DNA polymerase activities. Has also a 5'-deoxyribose-5-phosphate lyase (dRP lyase) activity.	Uracil-DNA glycosylase; Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine.	0.598
A0A194YIA1	A0A1B6Q5I4	A0A194YIA1	A0A1B6Q5I4	DNA polymerase; DNA polymerase that functions in several pathways of DNA repair. Involved in base excision repair (BER) responsible for repair of lesions that give rise to abasic (AP) sites in DNA. Also contributes to DNA double-strand break repair by non-homologous end joining and homologous recombination. Has both template-dependent and template- independent (terminal transferase) DNA polymerase activities. Has also a 5'-deoxyribose-5-phosphate lyase (dRP lyase) activity.	DNA ligase.	0.960
A0A194YIA1	A0A1B6Q6M5	A0A194YIA1	A0A1B6Q6M5	DNA polymerase; DNA polymerase that functions in several pathways of DNA repair. Involved in base excision repair (BER) responsible for repair of lesions that give rise to abasic (AP) sites in DNA. Also contributes to DNA double-strand break repair by non-homologous end joining and homologous recombination. Has both template-dependent and template- independent (terminal transferase) DNA polymerase activities. Has also a 5'-deoxyribose-5-phosphate lyase (dRP lyase) activity.	SAP domain-containing protein.	0.767
A0A194YIA1	A0A1B6QAL7	A0A194YIA1	A0A1B6QAL7	DNA polymerase; DNA polymerase that functions in several pathways of DNA repair. Involved in base excision repair (BER) responsible for repair of lesions that give rise to abasic (AP) sites in DNA. Also contributes to DNA double-strand break repair by non-homologous end joining and homologous recombination. Has both template-dependent and template- independent (terminal transferase) DNA polymerase activities. Has also a 5'-deoxyribose-5-phosphate lyase (dRP lyase) activity.	Poly [ADP-ribose] polymerase.	0.617
A0A194YIA1	A0A1B6QCQ5	A0A194YIA1	A0A1B6QCQ5	DNA polymerase; DNA polymerase that functions in several pathways of DNA repair. Involved in base excision repair (BER) responsible for repair of lesions that give rise to abasic (AP) sites in DNA. Also contributes to DNA double-strand break repair by non-homologous end joining and homologous recombination. Has both template-dependent and template- independent (terminal transferase) DNA polymerase activities. Has also a 5'-deoxyribose-5-phosphate lyase (dRP lyase) activity.	SAM domain-containing protein.	0.667
A0A194YIA1	A0A1B6QGN0	A0A194YIA1	A0A1B6QGN0	DNA polymerase; DNA polymerase that functions in several pathways of DNA repair. Involved in base excision repair (BER) responsible for repair of lesions that give rise to abasic (AP) sites in DNA. Also contributes to DNA double-strand break repair by non-homologous end joining and homologous recombination. Has both template-dependent and template- independent (terminal transferase) DNA polymerase activities. Has also a 5'-deoxyribose-5-phosphate lyase (dRP lyase) activity.	ATP-dependent DNA helicase 2 subunit KU80; Single-stranded DNA-dependent ATP-dependent helicase.	0.846
A0A194YIA1	A0A1B6QNS7	A0A194YIA1	A0A1B6QNS7	DNA polymerase; DNA polymerase that functions in several pathways of DNA repair. Involved in base excision repair (BER) responsible for repair of lesions that give rise to abasic (AP) sites in DNA. Also contributes to DNA double-strand break repair by non-homologous end joining and homologous recombination. Has both template-dependent and template- independent (terminal transferase) DNA polymerase activities. Has also a 5'-deoxyribose-5-phosphate lyase (dRP lyase) activity.	Macro domain-containing protein.	0.940
A0A194YIA1	A0A1W0VZC1	A0A194YIA1	A0A1W0VZC1	DNA polymerase; DNA polymerase that functions in several pathways of DNA repair. Involved in base excision repair (BER) responsible for repair of lesions that give rise to abasic (AP) sites in DNA. Also contributes to DNA double-strand break repair by non-homologous end joining and homologous recombination. Has both template-dependent and template- independent (terminal transferase) DNA polymerase activities. Has also a 5'-deoxyribose-5-phosphate lyase (dRP lyase) activity.	Uncharacterized protein.	0.980
A0A194YIA1	A0A1W0W0P3	A0A194YIA1	A0A1W0W0P3	DNA polymerase; DNA polymerase that functions in several pathways of DNA repair. Involved in base excision repair (BER) responsible for repair of lesions that give rise to abasic (AP) sites in DNA. Also contributes to DNA double-strand break repair by non-homologous end joining and homologous recombination. Has both template-dependent and template- independent (terminal transferase) DNA polymerase activities. Has also a 5'-deoxyribose-5-phosphate lyase (dRP lyase) activity.	53EXOc domain-containing protein.	0.722
A0A194YIA1	A0A1Z5R6E2	A0A194YIA1	A0A1Z5R6E2	DNA polymerase; DNA polymerase that functions in several pathways of DNA repair. Involved in base excision repair (BER) responsible for repair of lesions that give rise to abasic (AP) sites in DNA. Also contributes to DNA double-strand break repair by non-homologous end joining and homologous recombination. Has both template-dependent and template- independent (terminal transferase) DNA polymerase activities. Has also a 5'-deoxyribose-5-phosphate lyase (dRP lyase) activity.	Adenine DNA glycosylase; Adenine glycosylase active on G-A mispairs.	0.591
A0A194YIA1	A0A1Z5REU4	A0A194YIA1	A0A1Z5REU4	DNA polymerase; DNA polymerase that functions in several pathways of DNA repair. Involved in base excision repair (BER) responsible for repair of lesions that give rise to abasic (AP) sites in DNA. Also contributes to DNA double-strand break repair by non-homologous end joining and homologous recombination. Has both template-dependent and template- independent (terminal transferase) DNA polymerase activities. Has also a 5'-deoxyribose-5-phosphate lyase (dRP lyase) activity.	DNA ligase.	0.930
A0A194YIA1	C5WSZ7_SORBI	A0A194YIA1	C5WSZ7	DNA polymerase; DNA polymerase that functions in several pathways of DNA repair. Involved in base excision repair (BER) responsible for repair of lesions that give rise to abasic (AP) sites in DNA. Also contributes to DNA double-strand break repair by non-homologous end joining and homologous recombination. Has both template-dependent and template- independent (terminal transferase) DNA polymerase activities. Has also a 5'-deoxyribose-5-phosphate lyase (dRP lyase) activity.	Uncharacterized protein.	0.649
A0A194YIA1	C5X199_SORBI	A0A194YIA1	C5X199	DNA polymerase; DNA polymerase that functions in several pathways of DNA repair. Involved in base excision repair (BER) responsible for repair of lesions that give rise to abasic (AP) sites in DNA. Also contributes to DNA double-strand break repair by non-homologous end joining and homologous recombination. Has both template-dependent and template- independent (terminal transferase) DNA polymerase activities. Has also a 5'-deoxyribose-5-phosphate lyase (dRP lyase) activity.	Uncharacterized protein.	0.635
A0A194YIA1	C5X1A7_SORBI	A0A194YIA1	C5X1A7	DNA polymerase; DNA polymerase that functions in several pathways of DNA repair. Involved in base excision repair (BER) responsible for repair of lesions that give rise to abasic (AP) sites in DNA. Also contributes to DNA double-strand break repair by non-homologous end joining and homologous recombination. Has both template-dependent and template- independent (terminal transferase) DNA polymerase activities. Has also a 5'-deoxyribose-5-phosphate lyase (dRP lyase) activity.	Uncharacterized protein.	0.980
A0A194YIA1	C5X6U3_SORBI	A0A194YIA1	C5X6U3	DNA polymerase; DNA polymerase that functions in several pathways of DNA repair. Involved in base excision repair (BER) responsible for repair of lesions that give rise to abasic (AP) sites in DNA. Also contributes to DNA double-strand break repair by non-homologous end joining and homologous recombination. Has both template-dependent and template- independent (terminal transferase) DNA polymerase activities. Has also a 5'-deoxyribose-5-phosphate lyase (dRP lyase) activity.	Uncharacterized protein.	0.767
A0A194YIA1	C5X745_SORBI	A0A194YIA1	C5X745	DNA polymerase; DNA polymerase that functions in several pathways of DNA repair. Involved in base excision repair (BER) responsible for repair of lesions that give rise to abasic (AP) sites in DNA. Also contributes to DNA double-strand break repair by non-homologous end joining and homologous recombination. Has both template-dependent and template- independent (terminal transferase) DNA polymerase activities. Has also a 5'-deoxyribose-5-phosphate lyase (dRP lyase) activity.	SAP domain-containing protein.	0.826
A0A194YIA1	C5XB55_SORBI	A0A194YIA1	C5XB55	DNA polymerase; DNA polymerase that functions in several pathways of DNA repair. Involved in base excision repair (BER) responsible for repair of lesions that give rise to abasic (AP) sites in DNA. Also contributes to DNA double-strand break repair by non-homologous end joining and homologous recombination. Has both template-dependent and template- independent (terminal transferase) DNA polymerase activities. Has also a 5'-deoxyribose-5-phosphate lyase (dRP lyase) activity.	SAP domain-containing protein.	0.826
A0A194YIA1	C5XJW6_SORBI	A0A194YIA1	C5XJW6	DNA polymerase; DNA polymerase that functions in several pathways of DNA repair. Involved in base excision repair (BER) responsible for repair of lesions that give rise to abasic (AP) sites in DNA. Also contributes to DNA double-strand break repair by non-homologous end joining and homologous recombination. Has both template-dependent and template- independent (terminal transferase) DNA polymerase activities. Has also a 5'-deoxyribose-5-phosphate lyase (dRP lyase) activity.	Poly [ADP-ribose] polymerase.	0.617
A0A194YIA1	C5XJX0_SORBI	A0A194YIA1	C5XJX0	DNA polymerase; DNA polymerase that functions in several pathways of DNA repair. Involved in base excision repair (BER) responsible for repair of lesions that give rise to abasic (AP) sites in DNA. Also contributes to DNA double-strand break repair by non-homologous end joining and homologous recombination. Has both template-dependent and template- independent (terminal transferase) DNA polymerase activities. Has also a 5'-deoxyribose-5-phosphate lyase (dRP lyase) activity.	Poly [ADP-ribose] polymerase.	0.617

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