(97 nodes) Cytokine Signaling in Immune system network (Sorghum bicolor)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	A0A194YGP1	Proteasome subunit beta; The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH; Belongs to the peptidase T1B family. (273 aa)
	A0A194YGU2	Uncharacterized protein. (587 aa)
	A0A194YJ98	Uncharacterized protein. (658 aa)
	A0A194YK10	Vac14_Fab1_bd domain-containing protein. (587 aa)
	A0A194YKY7	Uncharacterized protein. (273 aa)
	A0A194YLP4	HATPase_c domain-containing protein. (807 aa)
	A0A194YMW6	Uncharacterized protein. (457 aa)
	A0A194YMZ4	BZIP domain-containing protein. (320 aa)
	A0A194YPI2	GB1/RHD3-type G domain-containing protein. (1080 aa)
	A0A194YPR8	Uncharacterized protein. (882 aa)
	A0A194YQE8	Uncharacterized protein. (606 aa)
	A0A1B6PAJ4	TMEM189_B_dmain domain-containing protein. (260 aa)
	A0A1B6PN20	26S proteasome non-ATPase regulatory subunit 1 homolog; Acts as a regulatory subunit of the 26S proteasome which is involved in the ATP-dependent degradation of ubiquitinated proteins. (1008 aa)
	A0A1B6PRB3	Uncharacterized protein. (221 aa)
	A0A1B6PRE7	Uncharacterized protein. (215 aa)
	A0A1B6Q1J7	PsaL domain-containing protein. (211 aa)
	A0A1B6Q8F9	Uncharacterized protein. (443 aa)
	A0A1B6Q9E3	BZIP domain-containing protein. (404 aa)
	A0A1B6QAA8	Ubiquitin-like domain-containing protein. (104 aa)
	A0A1B6QDK3	Uncharacterized protein. (205 aa)
	A0A1B6QEU1	Uncharacterized protein. (305 aa)
	A0A1B6QH55	ADF-H domain-containing protein; Belongs to the actin-binding proteins ADF family. (139 aa)
	A0A1B6QH80	ADF-H domain-containing protein; Belongs to the actin-binding proteins ADF family. (211 aa)
	A0A1B6QHC8	Serine/threonine-protein phosphatase. (307 aa)
	A0A1B6QHZ4	COR domain-containing protein. (1388 aa)
	A0A1B6QK27	Ubiquitin-like domain-containing protein. (160 aa)
	A0A1B6QK90	Uncharacterized protein. (335 aa)
	A0A1B6QK96	Uncharacterized protein. (319 aa)
	A0A1B6QL86	Uncharacterized protein. (137 aa)
	A0A1B6QM99	ADF-H domain-containing protein; Belongs to the actin-binding proteins ADF family. (189 aa)
	A0A1W0VSN4	Uncharacterized protein. (1809 aa)
	A0A1W0VSN7	Uncharacterized protein. (857 aa)
	A0A1W0VUI0	Uncharacterized protein. (455 aa)
	A0A1W0VUR3	Uncharacterized protein; Belongs to the DEAD box helicase family. (517 aa)
	A0A1W0VVK5	Uncharacterized protein. (158 aa)
	A0A1W0W3X5	Uncharacterized protein. (187 aa)
	A0A1W0W5M8	Ubiquitin-like domain-containing protein. (190 aa)
	A0A1W0W7N7	Ubiquitin-like domain-containing protein. (184 aa)
	A0A1Z5RMG2	Uncharacterized protein; Belongs to the DEAD box helicase family. (765 aa)
	A0A1Z5RPL6	RING-type domain-containing protein. (113 aa)
	A0A1Z5S465	Uncharacterized protein. (175 aa)
	A0A1Z5SAI7	ADF-H domain-containing protein; Belongs to the actin-binding proteins ADF family. (204 aa)
	A0A1Z5SAX2	Uncharacterized protein. (101 aa)
	C5WM64_SORBI	Serine/threonine-protein phosphatase. (315 aa)
	C5WPD3_SORBI	ADF-H domain-containing protein; Belongs to the actin-binding proteins ADF family. (139 aa)
	C5WQ71_SORBI	Uncharacterized protein; Belongs to the eukaryotic initiation factor 4E family. (229 aa)
	C5WRR1_SORBI	Uncharacterized protein. (604 aa)
	C5WWS9_SORBI	Serine/threonine-protein phosphatase. (385 aa)
	C5WX70_SORBI	BZIP domain-containing protein. (405 aa)
	C5WX71_SORBI	GB1/RHD3-type G domain-containing protein. (614 aa)
	C5WZ27_SORBI	ADF-H domain-containing protein; Belongs to the actin-binding proteins ADF family. (145 aa)
	C5WZC2_SORBI	Cellulose synthase; Belongs to the glycosyltransferase 2 family. Plant cellulose synthase subfamily. (1058 aa)
	C5WZC3_SORBI	Uncharacterized protein; Belongs to the eukaryotic initiation factor 4E family. (210 aa)
	C5X1Y0_SORBI	Proteasome subunit beta; The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH; Belongs to the peptidase T1B family. (273 aa)
	C5X6V1_SORBI	Proteasome subunit alpha type; The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH; Belongs to the peptidase T1A family. (249 aa)
	C5X7Y0_SORBI	Ubiquitin-like domain-containing protein. (111 aa)
	C5X8K9_SORBI	ADF-H domain-containing protein; Belongs to the actin-binding proteins ADF family. (139 aa)
	C5XB30_SORBI	BZIP domain-containing protein. (445 aa)
	C5XB34_SORBI	GB1/RHD3-type G domain-containing protein. (603 aa)
	C5XCV9_SORBI	Uncharacterized protein. (153 aa)
	C5XEZ9_SORBI	RING-type domain-containing protein. (124 aa)
	C5XIY6_SORBI	Ubiquitin-like domain-containing protein. (155 aa)
	C5XJC8_SORBI	Uncharacterized protein; Belongs to the eukaryotic initiation factor 4E family. (220 aa)
	C5XLD8_SORBI	Uncharacterized protein. (1179 aa)
	C5XQM7_SORBI	Uncharacterized protein; Belongs to the BolA/IbaG family. (93 aa)
	C5XTH0_SORBI	Uncharacterized protein. (223 aa)
	C5XTW7_SORBI	Proteasome subunit alpha type; The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH; Belongs to the peptidase T1A family. (270 aa)
	C5XUM2_SORBI	Uncharacterized protein; Belongs to the DEAD box helicase family. (410 aa)
	C5XWR4_SORBI	Uncharacterized protein; Belongs to the DEAD box helicase family. (407 aa)
	C5XY23_SORBI	Serine/threonine-protein phosphatase. (306 aa)
	C5XY75_SORBI	Uncharacterized protein. (573 aa)
	C5Y0G2_SORBI	Uncharacterized protein. (459 aa)
	C5Y1E7_SORBI	ADF-H domain-containing protein; Belongs to the actin-binding proteins ADF family. (139 aa)
	C5YDK2_SORBI	ADF-H domain-containing protein; Belongs to the actin-binding proteins ADF family. (139 aa)
	C5YGJ5_SORBI	Uncharacterized protein. (153 aa)
	C5YH21_SORBI	PCI domain-containing protein. (496 aa)
	C5YH32_SORBI	Proteasome subunit alpha type; The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH; Belongs to the peptidase T1A family. (249 aa)
	C5YH49_SORBI	Proteasome subunit beta; The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH; Belongs to the peptidase T1B family. (245 aa)
	C5YI08_SORBI	TMEM189_B_dmain domain-containing protein. (313 aa)
	C5YIV0_SORBI	Uncharacterized protein. (225 aa)
	C5YIY1_SORBI	26S proteasome non-ATPase regulatory subunit 1 homolog; Acts as a regulatory subunit of the 26S proteasome which is involved in the ATP-dependent degradation of ubiquitinated proteins. (988 aa)
	C5YLQ8_SORBI	Uncharacterized protein. (870 aa)
	C5YMG4_SORBI	Uncharacterized protein. (733 aa)
	C5YPY1_SORBI	Importin N-terminal domain-containing protein. (872 aa)
	C5YRE4_SORBI	BZIP domain-containing protein. (317 aa)
	C5YVF7_SORBI	Uncharacterized protein. (523 aa)
	C5YVJ3_SORBI	GB1/RHD3-type G domain-containing protein. (1051 aa)
	C5YWA7_SORBI	Importin N-terminal domain-containing protein. (870 aa)
	C5YYL3_SORBI	ADF-H domain-containing protein; Belongs to the actin-binding proteins ADF family. (139 aa)
	C5Z0N6_SORBI	Ubiquitin-like domain-containing protein. (155 aa)
	C5Z3R9_SORBI	Proteasome subunit beta; The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH; Belongs to the peptidase T1B family. (245 aa)
	C5Z4C7_SORBI	Proteasome subunit beta; The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH; Belongs to the peptidase T1B family. (280 aa)
	C5Z545_SORBI	Serine/threonine-protein phosphatase. (306 aa)
	C5Z6E3_SORBI	Uncharacterized protein. (216 aa)
	C5Z6U2_SORBI	Uncharacterized protein. (153 aa)
	C5Z7B6_SORBI	BZIP domain-containing protein. (287 aa)
	C5Z862_SORBI	Uncharacterized protein. (292 aa)

Your Current Organism:

Sorghum bicolor

NCBI taxonomy Id: 4558
Other names: Andropogon sorghum, Andropogon sorghum (L.) Brot., S. bicolor, Sorghum bicolor (L.) Moench, Sorghum bicolor subsp. bicolor, Sorghum nervosum, Sorghum nervosum Besser ex Schult., Sorghum saccharatum, Sorghum saccharatum (L.) Moench, Sorghum vulgare, Sorghum vulgare Pers., broomcorn, milo, sorghum

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
A0A194YGP1	A0A194YKY7	A0A194YGP1	A0A194YKY7	Proteasome subunit beta; The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH; Belongs to the peptidase T1B family.	Uncharacterized protein.	0.515
A0A194YGP1	A0A194YMW6	A0A194YGP1	A0A194YMW6	Proteasome subunit beta; The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH; Belongs to the peptidase T1B family.	Uncharacterized protein.	0.515
A0A194YGP1	A0A1B6PN20	A0A194YGP1	A0A1B6PN20	Proteasome subunit beta; The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH; Belongs to the peptidase T1B family.	26S proteasome non-ATPase regulatory subunit 1 homolog; Acts as a regulatory subunit of the 26S proteasome which is involved in the ATP-dependent degradation of ubiquitinated proteins.	0.949
A0A194YGP1	A0A1B6PRB3	A0A194YGP1	A0A1B6PRB3	Proteasome subunit beta; The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH; Belongs to the peptidase T1B family.	Uncharacterized protein.	0.515
A0A194YGP1	A0A1B6PRE7	A0A194YGP1	A0A1B6PRE7	Proteasome subunit beta; The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH; Belongs to the peptidase T1B family.	Uncharacterized protein.	0.515
A0A194YGP1	A0A1B6QAA8	A0A194YGP1	A0A1B6QAA8	Proteasome subunit beta; The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH; Belongs to the peptidase T1B family.	Ubiquitin-like domain-containing protein.	0.454
A0A194YGP1	A0A1B6QEU1	A0A194YGP1	A0A1B6QEU1	Proteasome subunit beta; The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH; Belongs to the peptidase T1B family.	Uncharacterized protein.	0.815
A0A194YGP1	A0A1B6QK27	A0A194YGP1	A0A1B6QK27	Proteasome subunit beta; The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH; Belongs to the peptidase T1B family.	Ubiquitin-like domain-containing protein.	0.822
A0A194YGP1	A0A1B6QK90	A0A194YGP1	A0A1B6QK90	Proteasome subunit beta; The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH; Belongs to the peptidase T1B family.	Uncharacterized protein.	0.515
A0A194YGP1	A0A1B6QK96	A0A194YGP1	A0A1B6QK96	Proteasome subunit beta; The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH; Belongs to the peptidase T1B family.	Uncharacterized protein.	0.515
A0A194YGP1	A0A1B6QL86	A0A194YGP1	A0A1B6QL86	Proteasome subunit beta; The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH; Belongs to the peptidase T1B family.	Uncharacterized protein.	0.515
A0A194YGP1	A0A1W0VSN4	A0A194YGP1	A0A1W0VSN4	Proteasome subunit beta; The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH; Belongs to the peptidase T1B family.	Uncharacterized protein.	0.929
A0A194YGP1	A0A1W0VUI0	A0A194YGP1	A0A1W0VUI0	Proteasome subunit beta; The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH; Belongs to the peptidase T1B family.	Uncharacterized protein.	0.515
A0A194YGP1	A0A1W0W5M8	A0A194YGP1	A0A1W0W5M8	Proteasome subunit beta; The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH; Belongs to the peptidase T1B family.	Ubiquitin-like domain-containing protein.	0.515
A0A194YGP1	A0A1W0W7N7	A0A194YGP1	A0A1W0W7N7	Proteasome subunit beta; The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH; Belongs to the peptidase T1B family.	Ubiquitin-like domain-containing protein.	0.454
A0A194YGP1	A0A1Z5RPL6	A0A194YGP1	A0A1Z5RPL6	Proteasome subunit beta; The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH; Belongs to the peptidase T1B family.	RING-type domain-containing protein.	0.541
A0A194YGP1	A0A1Z5S465	A0A194YGP1	A0A1Z5S465	Proteasome subunit beta; The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH; Belongs to the peptidase T1B family.	Uncharacterized protein.	0.515
A0A194YGP1	C5X1Y0_SORBI	A0A194YGP1	C5X1Y0	Proteasome subunit beta; The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH; Belongs to the peptidase T1B family.	Proteasome subunit beta; The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH; Belongs to the peptidase T1B family.	0.900
A0A194YGP1	C5X6V1_SORBI	A0A194YGP1	C5X6V1	Proteasome subunit beta; The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH; Belongs to the peptidase T1B family.	Proteasome subunit alpha type; The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH; Belongs to the peptidase T1A family.	0.985
A0A194YGP1	C5X7Y0_SORBI	A0A194YGP1	C5X7Y0	Proteasome subunit beta; The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH; Belongs to the peptidase T1B family.	Ubiquitin-like domain-containing protein.	0.515

page 1 of 79

Server load: low (10%) [HD]

Permalink

Network

Cooccurrence

Experiments

Coexpression

Databases

Neighborhood

Textmining

Fusion

© STRING Consortium 2025

Credits

Access

Info

About