(53 nodes) Tryptophan metabolism network (Sorghum bicolor)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	A0A194YIH8	Aldedh domain-containing protein; Belongs to the aldehyde dehydrogenase family. (556 aa)
	A0A194YPW6	Fe2OG dioxygenase domain-containing protein; Belongs to the iron/ascorbate-dependent oxidoreductase family. (340 aa)
	A0A1B6P913	N-acetyltransferase domain-containing protein. (241 aa)
	A0A1B6PEL7	Uncharacterized protein; Belongs to the thiolase-like superfamily. Thiolase family. (401 aa)
	A0A1B6PQI9	Aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family. (478 aa)
	A0A1B6Q1A9	Aminotran_1_2 domain-containing protein. (515 aa)
	A0A1B6Q1G1	Alliinase_C domain-containing protein. (538 aa)
	A0A1B6Q2G4	Uncharacterized protein; Belongs to the thiolase-like superfamily. Thiolase family. (421 aa)
	A0A1B6Q2V8	Flavin-containing monooxygenase. (406 aa)
	A0A1B6Q3D8	Uncharacterized protein. (561 aa)
	A0A1B6Q5W6	Flavin-containing monooxygenase. (436 aa)
	A0A1B6QAS1	Uncharacterized protein. (505 aa)
	A0A1B6QAS9	Flavin-containing monooxygenase. (425 aa)
	A0A1B6QE70	Amidase domain-containing protein. (494 aa)
	A0A1B6QL99	Amidase domain-containing protein. (543 aa)
	A0A1B6QMR1	Uncharacterized protein; Belongs to the thiolase-like superfamily. Thiolase family. (401 aa)
	A0A1B6QQQ9	Catalase; Occurs in almost all aerobically respiring organisms and serves to protect cells from the toxic effects of hydrogen peroxide. (492 aa)
	A0A1W0VYM9	Flavin-containing monooxygenase. (422 aa)
	A0A1Z5R512	Uncharacterized protein. (384 aa)
	A0A1Z5R7U7	Flavin-containing monooxygenase. (451 aa)
	A0A1Z5REV8	Aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family. (496 aa)
	A0A1Z5RKL6	Catalase; Occurs in almost all aerobically respiring organisms and serves to protect cells from the toxic effects of hydrogen peroxide. (514 aa)
	A0A1Z5SAV0	Lipoyl-binding domain-containing protein. (467 aa)
	A0A1Z5SBK3	Flavin-containing monooxygenase. (435 aa)
	C5WMA6_SORBI	Uncharacterized protein. (498 aa)
	C5WMF3_SORBI	Uncharacterized protein. (268 aa)
	C5WY36_SORBI	Uncharacterized protein. (1360 aa)
	C5WY40_SORBI	Uncharacterized protein. (1368 aa)
	C5X2G1_SORBI	Amidase domain-containing protein. (437 aa)
	C5X8I3_SORBI	Amidase domain-containing protein. (510 aa)
	C5X8J1_SORBI	Amidase domain-containing protein. (510 aa)
	C5XDP9_SORBI	Aldedh domain-containing protein; Belongs to the aldehyde dehydrogenase family. (509 aa)
	C5XFU6_SORBI	Uncharacterized protein. (509 aa)
	C5XFU7_SORBI	Uncharacterized protein. (502 aa)
	C5XIY9_SORBI	Dihydrolipoyl dehydrogenase. (504 aa)
	C5XKB5_SORBI	Flavin-containing monooxygenase. (426 aa)
	C5XS38_SORBI	Aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family. (486 aa)
	C5Y1Y6_SORBI	Uncharacterized protein. (376 aa)
	C5YAE8_SORBI	Fe2OG dioxygenase domain-containing protein; Belongs to the iron/ascorbate-dependent oxidoreductase family. (298 aa)
	C5YBT6_SORBI	Flavin-containing monooxygenase. (422 aa)
	C5YCU5_SORBI	Amidase domain-containing protein. (513 aa)
	C5YCU6_SORBI	Amidase domain-containing protein. (494 aa)
	C5YMR8_SORBI	Uncharacterized protein. (443 aa)
	C5YN24_SORBI	Uncharacterized protein. (521 aa)
	C5YN26_SORBI	Uncharacterized protein. (519 aa)
	C5YP57_SORBI	Uncharacterized protein. (448 aa)
	C5YST8_SORBI	Aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family. (487 aa)
	C5Z0L0_SORBI	Dihydrolipoyl dehydrogenase. (562 aa)
	C5Z0N4_SORBI	Dihydrolipoyl dehydrogenase. (500 aa)
	C5Z128_SORBI	Alliinase_C domain-containing protein. (432 aa)
	C5Z130_SORBI	DUF1421 domain-containing protein. (582 aa)
	C5Z2J6_SORBI	Catalase; Occurs in almost all aerobically respiring organisms and serves to protect cells from the toxic effects of hydrogen peroxide. (492 aa)
	ALDH2a	Mitochondrial aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family. (551 aa)

Your Current Organism:

Sorghum bicolor

NCBI taxonomy Id: 4558
Other names: Andropogon sorghum, Andropogon sorghum (L.) Brot., S. bicolor, Sorghum bicolor (L.) Moench, Sorghum bicolor subsp. bicolor, Sorghum nervosum, Sorghum nervosum Besser ex Schult., Sorghum saccharatum, Sorghum saccharatum (L.) Moench, Sorghum vulgare, Sorghum vulgare Pers., broomcorn, milo, sorghum

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
A0A194YIH8	A0A194YPW6	A0A194YIH8	A0A194YPW6	Aldedh domain-containing protein; Belongs to the aldehyde dehydrogenase family.	Fe2OG dioxygenase domain-containing protein; Belongs to the iron/ascorbate-dependent oxidoreductase family.	0.900
A0A194YIH8	A0A1B6PEL7	A0A194YIH8	A0A1B6PEL7	Aldedh domain-containing protein; Belongs to the aldehyde dehydrogenase family.	Uncharacterized protein; Belongs to the thiolase-like superfamily. Thiolase family.	0.569
A0A194YIH8	A0A1B6Q2G4	A0A194YIH8	A0A1B6Q2G4	Aldedh domain-containing protein; Belongs to the aldehyde dehydrogenase family.	Uncharacterized protein; Belongs to the thiolase-like superfamily. Thiolase family.	0.606
A0A194YIH8	A0A1B6Q2V8	A0A194YIH8	A0A1B6Q2V8	Aldedh domain-containing protein; Belongs to the aldehyde dehydrogenase family.	Flavin-containing monooxygenase.	0.676
A0A194YIH8	A0A1B6Q3D8	A0A194YIH8	A0A1B6Q3D8	Aldedh domain-containing protein; Belongs to the aldehyde dehydrogenase family.	Uncharacterized protein.	0.453
A0A194YIH8	A0A1B6Q5W6	A0A194YIH8	A0A1B6Q5W6	Aldedh domain-containing protein; Belongs to the aldehyde dehydrogenase family.	Flavin-containing monooxygenase.	0.676
A0A194YIH8	A0A1B6QAS9	A0A194YIH8	A0A1B6QAS9	Aldedh domain-containing protein; Belongs to the aldehyde dehydrogenase family.	Flavin-containing monooxygenase.	0.676
A0A194YIH8	A0A1B6QE70	A0A194YIH8	A0A1B6QE70	Aldedh domain-containing protein; Belongs to the aldehyde dehydrogenase family.	Amidase domain-containing protein.	0.699
A0A194YIH8	A0A1B6QL99	A0A194YIH8	A0A1B6QL99	Aldedh domain-containing protein; Belongs to the aldehyde dehydrogenase family.	Amidase domain-containing protein.	0.699
A0A194YIH8	A0A1B6QMR1	A0A194YIH8	A0A1B6QMR1	Aldedh domain-containing protein; Belongs to the aldehyde dehydrogenase family.	Uncharacterized protein; Belongs to the thiolase-like superfamily. Thiolase family.	0.569
A0A194YIH8	A0A1W0VYM9	A0A194YIH8	A0A1W0VYM9	Aldedh domain-containing protein; Belongs to the aldehyde dehydrogenase family.	Flavin-containing monooxygenase.	0.676
A0A194YIH8	A0A1Z5R512	A0A194YIH8	A0A1Z5R512	Aldedh domain-containing protein; Belongs to the aldehyde dehydrogenase family.	Uncharacterized protein.	0.676
A0A194YIH8	A0A1Z5R7U7	A0A194YIH8	A0A1Z5R7U7	Aldedh domain-containing protein; Belongs to the aldehyde dehydrogenase family.	Flavin-containing monooxygenase.	0.676
A0A194YIH8	A0A1Z5SAV0	A0A194YIH8	A0A1Z5SAV0	Aldedh domain-containing protein; Belongs to the aldehyde dehydrogenase family.	Lipoyl-binding domain-containing protein.	0.648
A0A194YIH8	A0A1Z5SBK3	A0A194YIH8	A0A1Z5SBK3	Aldedh domain-containing protein; Belongs to the aldehyde dehydrogenase family.	Flavin-containing monooxygenase.	0.676
A0A194YIH8	C5X2G1_SORBI	A0A194YIH8	C5X2G1	Aldedh domain-containing protein; Belongs to the aldehyde dehydrogenase family.	Amidase domain-containing protein.	0.699
A0A194YIH8	C5X8I3_SORBI	A0A194YIH8	C5X8I3	Aldedh domain-containing protein; Belongs to the aldehyde dehydrogenase family.	Amidase domain-containing protein.	0.699
A0A194YIH8	C5X8J1_SORBI	A0A194YIH8	C5X8J1	Aldedh domain-containing protein; Belongs to the aldehyde dehydrogenase family.	Amidase domain-containing protein.	0.699
A0A194YIH8	C5XIY9_SORBI	A0A194YIH8	C5XIY9	Aldedh domain-containing protein; Belongs to the aldehyde dehydrogenase family.	Dihydrolipoyl dehydrogenase.	0.453
A0A194YIH8	C5XKB5_SORBI	A0A194YIH8	C5XKB5	Aldedh domain-containing protein; Belongs to the aldehyde dehydrogenase family.	Flavin-containing monooxygenase.	0.676

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