(39 nodes) Pantothenate and CoA biosynthesis network (Sorghum bicolor)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	A0A194YIH8	Aldedh domain-containing protein; Belongs to the aldehyde dehydrogenase family. (556 aa)
	A0A194YIY9	Uncharacterized protein. (663 aa)
	A0A1B6PMJ9	Branched-chain-amino-acid aminotransferase; Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family. (553 aa)
	A0A1B6PQI9	Aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family. (478 aa)
	A0A1B6QGU9	Uncharacterized protein. (335 aa)
	A0A1B6QM25	Branched-chain-amino-acid aminotransferase; Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family. (443 aa)
	A0A1B6QR82	Branched-chain-amino-acid aminotransferase; Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family. (404 aa)
	A0A1W0W2D1	CTP_transf_like domain-containing protein. (188 aa)
	A0A1Z5REV8	Aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family. (496 aa)
	A0A1Z5RMP2	Acetolactate synthase. (641 aa)
	A0A1Z5SAL0	Branched-chain-amino-acid aminotransferase; Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family. (417 aa)
	C5WMP5_SORBI	ACPS domain-containing protein. (320 aa)
	C5X682_SORBI	Pantothenate kinase 2; Catalyzes the phosphorylation of pantothenate the first step in CoA biosynthesis. May play a role in the physiological regulation of the intracellular CoA concentration. (902 aa)
	C5X8L4_SORBI	CN hydrolase domain-containing protein. (413 aa)
	C5XF87_SORBI	Ketol-acid reductoisomerase; Belongs to the ketol-acid reductoisomerase family. (579 aa)
	C5XKA7_SORBI	3-methyl-2-oxobutanoate hydroxymethyltransferase; Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha- ketoisovalerate to form ketopantoate. (404 aa)
	C5XKA8_SORBI	3-methyl-2-oxobutanoate hydroxymethyltransferase; Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha- ketoisovalerate to form ketopantoate. (370 aa)
	C5XKA9_SORBI	3-methyl-2-oxobutanoate hydroxymethyltransferase; Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha- ketoisovalerate to form ketopantoate. (353 aa)
	C5XKI1_SORBI	Uncharacterized protein. (232 aa)
	C5XLV1_SORBI	Flavoprotein domain-containing protein. (200 aa)
	C5XLV5_SORBI	Uncharacterized protein. (470 aa)
	C5XMK0_SORBI	Amidohydro-rel domain-containing protein. (536 aa)
	C5XS38_SORBI	Aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family. (486 aa)
	C5XTW9_SORBI	CTP_transf_like domain-containing protein. (225 aa)
	C5XVP2_SORBI	Uncharacterized protein. (332 aa)
	C5XX95_SORBI	Uncharacterized protein. (492 aa)
	C5XZ92_SORBI	DHO_dh domain-containing protein. (420 aa)
	C5Y426_SORBI	ACPS domain-containing protein. (276 aa)
	C5Y7K7_SORBI	Uncharacterized protein. (476 aa)
	C5YA47_SORBI	Amino_oxidase domain-containing protein. (487 aa)
	C5YA49_SORBI	Amino_oxidase domain-containing protein. (491 aa)
	C5YG61_SORBI	Amino_oxidase domain-containing protein. (483 aa)
	C5YHW1_SORBI	Uncharacterized protein. (321 aa)
	C5YLK2_SORBI	Uncharacterized protein. (230 aa)
	C5YN64_SORBI	Uncharacterized protein. (591 aa)
	C5YST8_SORBI	Aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family. (487 aa)
	C5YW13_SORBI	Ketol-acid reductoisomerase; Belongs to the ketol-acid reductoisomerase family. (587 aa)
	C5Z607_SORBI	Flavoprotein domain-containing protein. (220 aa)
	ALDH2a	Mitochondrial aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family. (551 aa)

Your Current Organism:

Sorghum bicolor

NCBI taxonomy Id: 4558
Other names: Andropogon sorghum, Andropogon sorghum (L.) Brot., S. bicolor, Sorghum bicolor (L.) Moench, Sorghum bicolor subsp. bicolor, Sorghum nervosum, Sorghum nervosum Besser ex Schult., Sorghum saccharatum, Sorghum saccharatum (L.) Moench, Sorghum vulgare, Sorghum vulgare Pers., broomcorn, milo, sorghum

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
A0A194YIH8	A0A1B6QGU9	A0A194YIH8	A0A1B6QGU9	Aldedh domain-containing protein; Belongs to the aldehyde dehydrogenase family.	Uncharacterized protein.	0.909
A0A194YIH8	A0A1Z5RMP2	A0A194YIH8	A0A1Z5RMP2	Aldedh domain-containing protein; Belongs to the aldehyde dehydrogenase family.	Acetolactate synthase.	0.524
A0A194YIH8	C5X8L4_SORBI	A0A194YIH8	C5X8L4	Aldedh domain-containing protein; Belongs to the aldehyde dehydrogenase family.	CN hydrolase domain-containing protein.	0.921
A0A194YIH8	C5YA47_SORBI	A0A194YIH8	C5YA47	Aldedh domain-containing protein; Belongs to the aldehyde dehydrogenase family.	Amino_oxidase domain-containing protein.	0.928
A0A194YIH8	C5YA49_SORBI	A0A194YIH8	C5YA49	Aldedh domain-containing protein; Belongs to the aldehyde dehydrogenase family.	Amino_oxidase domain-containing protein.	0.928
A0A194YIH8	C5YG61_SORBI	A0A194YIH8	C5YG61	Aldedh domain-containing protein; Belongs to the aldehyde dehydrogenase family.	Amino_oxidase domain-containing protein.	0.928
A0A194YIY9	A0A1B6QGU9	A0A194YIY9	A0A1B6QGU9	Uncharacterized protein.	Uncharacterized protein.	0.989
A0A194YIY9	A0A1W0W2D1	A0A194YIY9	A0A1W0W2D1	Uncharacterized protein.	CTP_transf_like domain-containing protein.	0.957
A0A194YIY9	C5X682_SORBI	A0A194YIY9	C5X682	Uncharacterized protein.	Pantothenate kinase 2; Catalyzes the phosphorylation of pantothenate the first step in CoA biosynthesis. May play a role in the physiological regulation of the intracellular CoA concentration.	0.950
A0A194YIY9	C5XKA7_SORBI	A0A194YIY9	C5XKA7	Uncharacterized protein.	3-methyl-2-oxobutanoate hydroxymethyltransferase; Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha- ketoisovalerate to form ketopantoate.	0.555
A0A194YIY9	C5XKA8_SORBI	A0A194YIY9	C5XKA8	Uncharacterized protein.	3-methyl-2-oxobutanoate hydroxymethyltransferase; Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha- ketoisovalerate to form ketopantoate.	0.555
A0A194YIY9	C5XKA9_SORBI	A0A194YIY9	C5XKA9	Uncharacterized protein.	3-methyl-2-oxobutanoate hydroxymethyltransferase; Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha- ketoisovalerate to form ketopantoate.	0.555
A0A194YIY9	C5XKI1_SORBI	A0A194YIY9	C5XKI1	Uncharacterized protein.	Uncharacterized protein.	0.598
A0A194YIY9	C5XLV1_SORBI	A0A194YIY9	C5XLV1	Uncharacterized protein.	Flavoprotein domain-containing protein.	0.973
A0A194YIY9	C5XLV5_SORBI	A0A194YIY9	C5XLV5	Uncharacterized protein.	Uncharacterized protein.	0.901
A0A194YIY9	C5XTW9_SORBI	A0A194YIY9	C5XTW9	Uncharacterized protein.	CTP_transf_like domain-containing protein.	0.957
A0A194YIY9	C5XVP2_SORBI	A0A194YIY9	C5XVP2	Uncharacterized protein.	Uncharacterized protein.	0.986
A0A194YIY9	C5YHW1_SORBI	A0A194YIY9	C5YHW1	Uncharacterized protein.	Uncharacterized protein.	0.986
A0A194YIY9	C5YLK2_SORBI	A0A194YIY9	C5YLK2	Uncharacterized protein.	Uncharacterized protein.	0.598
A0A194YIY9	C5Z607_SORBI	A0A194YIY9	C5Z607	Uncharacterized protein.	Flavoprotein domain-containing protein.	0.973

page 1 of 19

Server load: low (26%) [HD]

Permalink

Network

Neighborhood

Experiments

Fusion

Databases

Cooccurrence

Textmining

Coexpression

© STRING Consortium 2025

Credits

Access

Info

About