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phoP phoP atpD atpD xpsE xpsE pilB pilB xopN xopN infB infB gumB gumB gumK gumK gumM gumM gumP gumP kefB kefB xopE2 xopE2 recA recA dnaK dnaK grpE grpE hrpG hrpG secA secA kdpD kdpD kdpC kdpC kdpB kdpB xopB xopB xopX xopX groL groL xopA xopA hpaA hpaA hpaB hpaB xopF1 xopF1 hrpF hrpF hpaG hpaG xopE1 xopE1 sodC2 sodC2 avrBs2 avrBs2 gyrB gyrB xopQ xopQ uvrD uvrD yapH yapH phoQ phoQ
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
phoPDNA-binding response regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. (227 aa)
atpDF0F1 ATP synthase subunit beta; Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits; Belongs to the ATPase alpha/beta chains family. (468 aa)
xpsEType II secretion system protein GspE; Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins. (575 aa)
pilBType IV-A pilus assembly ATPase PilB; Derived by automated computational analysis using gene prediction method: Protein Homology. (569 aa)
xopNType III secretion system effector protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (733 aa)
infBTranslation initiation factor IF-2; One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily. (904 aa)
gumBPolysaccharide biosynthesis protein GumB; Derived by automated computational analysis using gene prediction method: Protein Homology. (232 aa)
gumKUDP-glucuronate--glycolipid 2-beta-glucuronosyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (398 aa)
gumMGlycosyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the glycosyltransferase 26 family. (264 aa)
gumPMBL fold metallo-hydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology. (282 aa)
kefBPotassium transporter; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the monovalent cation:proton antiporter 2 (CPA2) transporter (TC 2.A.37) family. (616 aa)
xopE2Avirulence protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (358 aa)
recAHypothetical protein; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family. (344 aa)
dnaKMolecular chaperone DnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family. (641 aa)
grpENucleotide exchange factor GrpE; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds [...] (172 aa)
hrpGTranscriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. (263 aa)
secAPreprotein translocase subunit SecA; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving both as a receptor for the preprotein-SecB complex and as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane. Belongs to the SecA family. (912 aa)
kdpDHistidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (886 aa)
kdpCPotassium-transporting ATPase subunit C; Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP-binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB/KdpC/ATP ternary complex. (209 aa)
kdpBPotassium-transporting ATPase subunit B; Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system. Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IA subfamily. (682 aa)
xopBHypothetical protein; Incomplete; partial on complete genome; missing stop; Derived by automated computational analysis using gene prediction method: Protein Homology. (515 aa)
xopXType III secretion system effector protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (699 aa)
groLChaperonin GroL; Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions. (546 aa)
xopAHypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (113 aa)
hpaA4-hydroxyphenylacetate catabolism regulator HpaA; Derived by automated computational analysis using gene prediction method: Protein Homology. (275 aa)
hpaB4-hydroxyphenylacetate 3-monooxygenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (156 aa)
xopF1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (670 aa)
hrpFSerine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (806 aa)
hpaGHpaF protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (481 aa)
xopE1Avirulence protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (400 aa)
sodC2Superoxide dismutase; Destroys radicals which are normally produced within the cells and which are toxic to biological systems. Belongs to the Cu-Zn superoxide dismutase family. (215 aa)
avrBs2Avirulence protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (729 aa)
gyrBDNA gyrase subunit B; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner. (814 aa)
xopQHypothetical protein; Incomplete; partial on complete genome; missing stop; Derived by automated computational analysis using gene prediction method: Protein Homology. (464 aa)
uvrDDNA helicase II; Derived by automated computational analysis using gene prediction method: Protein Homology. (728 aa)
yapHHypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (2727 aa)
phoQTwo-component sensor histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (471 aa)
Your Current Organism:
Xanthomonas euvesicatoria
NCBI taxonomy Id: 456327
Other names: ATCC 11633, Bacterium vesicatorium, DSM 19128, ICMP 109, ICMP 98, NCPPB 2968, X. euvesicatoria, Xanthomonas campestris (pv. vesicatoria), Xanthomonas campestris pv. Vesicatoria type A, Xanthomonas campestris pv. vesicatoria, Xanthomonas euvesicatoria Jones et al. 2006 emend. Constantin et al. 2016
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