Your Input: | |
| | tyrS | tyrosyl-tRNA synthetase; Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two- step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr); Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 3 subfamily. (313 aa) |
| | pdxT | SNO glutamine amidotransferase; Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS. (199 aa) |
| | Mboo_0034 | Phosphoenolpyruvate synthase; Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate; Belongs to the PEP-utilizing enzyme family. (806 aa) |
| | Mboo_0043 | PFAM: beta-lactamase domain protein; KEGG: mhu:Mhun_2460 beta-lactamase-like. (200 aa) |
| | Mboo_0053 | PFAM: aminotransferase, class V; aromatic amino acid beta-eliminating lyase/threonine aldolase; KEGG: mhu:Mhun_2475 serine--glyoxylate transaminase. (376 aa) |
| | trpB | Pyridoxal-phosphate dependent TrpB-like enzyme; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine. (452 aa) |
| | Mboo_0066 | TIGRFAM: acetate--CoA ligase; PFAM: AMP-dependent synthetase and ligase; KEGG: mhu:Mhun_0352 acetate--CoA ligase. (632 aa) |
| | argC | N-acetyl-gamma-glutamyl-phosphate reductase; Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde. Belongs to the NAGSA dehydrogenase family. Type 1 subfamily. (328 aa) |
| | argJ | Arginine biosynthesis bifunctional protein ArgJ; Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis: the synthesis of N-acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate. Belongs to the ArgJ family. (385 aa) |
| | argB | Acetylglutamate kinase; Catalyzes the ATP-dependent phosphorylation of N-acetyl-L- glutamate; Belongs to the acetylglutamate kinase family. ArgB subfamily. (291 aa) |
| | Mboo_0074 | PFAM: Chorismate mutase; KEGG: nph:NP3980A chorismate mutase. (125 aa) |
| | Mboo_0087 | KEGG: mhu:Mhun_3054 aspartate kinase; TIGRFAM: aspartate kinase; aspartate kinase, monofunctional class; PFAM: aspartate/glutamate/uridylate kinase; amino acid-binding ACT domain protein; Belongs to the aspartokinase family. (465 aa) |
| | purF | Amidophosphoribosyltransferase; Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine. (476 aa) |
| | Mboo_0104 | PFAM: Methionine synthase, vitamin-B12 independent; Cobalamin-independent synthase MetE, N-terminal domain protein; KEGG: mhu:Mhun_2447 methionine synthase, vitamin-B12 independent. (300 aa) |
| | aspS | aspartyl-tRNA synthetase; Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp/Asn). (430 aa) |
| | Mboo_0107 | KEGG: mma:MM0843 coenzyme F390 synthetase/phenylacetyl-CoA ligase. (451 aa) |
| | cofD | LPPG; Catalyzes the transfer of the phosphoenolpyruvate moiety from enoylpyruvoyl-2-diphospho-5'-guanosine (EPPG) to 7,8-didemethyl-8- hydroxy-5-deazariboflavin (FO) with the formation of dehydro coenzyme F420-0 and GMP. (302 aa) |
| | Mboo_0123 | PFAM: protein of unknown function DUF521; KEGG: mhu:Mhun_2437 protein of unknown function DUF521. (392 aa) |
| | hisG | ATP phosphoribosyltransferase; Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity. Belongs to the ATP phosphoribosyltransferase family. Long subfamily. (290 aa) |
| | Mboo_0144 | PFAM: Orn/Lys/Arg decarboxylase, major region; Orn/Lys/Arg decarboxylase domain protein; KEGG: bam:Bamb_4345 lysine decarboxylase. (769 aa) |
| | Mboo_0147 | KEGG: mba:Mbar_A3450 uncharacterized membrane protein. (216 aa) |
| | Mboo_0156 | PFAM: Thiolase; KEGG: mhu:Mhun_0150 thiolase. (388 aa) |
| | Mboo_0169 | KEGG: rru:Rru_A0790 phenylacetate--CoA ligase. (433 aa) |
| | Mboo_0171 | PFAM: pyruvate flavodoxin/ferredoxin oxidoreductase domain protein; Transketolase domain protein; KEGG: sat:SYN_00692 pyruvate synthase alpha chain. (370 aa) |
| | Mboo_0172 | TIGRFAM: pyruvate/ketoisovalerate oxidoreductase, gamma subunit; PFAM: pyruvate ferredoxin/flavodoxin oxidoreductase; KEGG: sat:SYN_00693 pyruvate synthase gamma chain. (175 aa) |
| | Mboo_0173 | TIGRFAM: pyruvate ferredoxin/flavodoxin oxidoreductase, delta subunit; PFAM: 4Fe-4S ferredoxin, iron-sulfur binding domain protein; KEGG: mhu:Mhun_2393 2-oxoacid:acceptor oxidoreductase, delta subunit, pyruvate/2-ketoisovalerate. (85 aa) |
| | Mboo_0202 | TIGRFAM: pyruvate ferredoxin/flavodoxin oxidoreductase, delta subunit; PFAM: 4Fe-4S ferredoxin, iron-sulfur binding domain protein; KEGG: mhu:Mhun_2393 2-oxoacid:acceptor oxidoreductase, delta subunit, pyruvate/2-ketoisovalerate. (86 aa) |
| | Mboo_0203 | TIGRFAM: pyruvate/ketoisovalerate oxidoreductase, gamma subunit; PFAM: pyruvate ferredoxin/flavodoxin oxidoreductase; KEGG: mhu:Mhun_2394 2-oxoacid:acceptor oxidoreductase, gamma subunit, pyruvate/2-ketoisovalerate. (175 aa) |
| | Mboo_0204 | PFAM: pyruvate flavodoxin/ferredoxin oxidoreductase domain protein; Transketolase domain protein; KEGG: sat:SYN_00692 pyruvate synthase alpha chain. (370 aa) |
| | cbiA | Cobyrinic acid a,c-diamide synthase; Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source. Involved in the biosynthesis of the unique nickel-containing tetrapyrrole coenzyme F430, the prosthetic group of methyl-coenzyme M reductase (MCR), which plays a key role in methanogenesis and anaerobic methane oxidation. Catalyzes the ATP- dependent amidation of the two carboxylate groups at positions a and c of Ni-sirohydrochlorin, using L-glutamine or ammonia as the nitrogen source. (447 aa) |
| | trpA | Tryptophan synthase, alpha subunit; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate; Belongs to the TrpA family. (265 aa) |
| | trpB-2 | Tryptophan synthase, beta subunit; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine. (388 aa) |
| | trpF | PFAM: N-(5'phosphoribosyl)anthranilate isomerase (PRAI); KEGG: mhu:Mhun_1789 N-(5'phosphoribosyl)anthranilate isomerase (PRAI); Belongs to the TrpF family. (195 aa) |
| | Mboo_0225 | PFAM: Indole-3-glycerol phosphate synthase; KEGG: mhu:Mhun_1788 indole-3-glycerol-phosphate synthase. (251 aa) |
| | trpD | Anthranilate phosphoribosyltransferase; Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'- phosphoribosyl)-anthranilate (PRA). (339 aa) |
| | trpE | Anthranilate synthase; Part of a heterotetrameric complex that catalyzes the two- step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine-binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia. (515 aa) |
| | Mboo_0251 | PFAM: transferase hexapeptide repeat containing protein; KEGG: mhu:Mhun_2143 transferase hexapeptide repeat. (202 aa) |
| | glmS | Glucosamine--fructose-6-phosphate aminotransferase, isomerizing; Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source. (580 aa) |
| | Mboo_0257 | PFAM: cyclase family protein; KEGG: gme:Gmet_0042 putative cyclase. (203 aa) |
| | Mboo_0261 | PFAM: peptidase M20; peptidase dimerisation domain protein; KEGG: mbo:Mb2551c hypothetical protein. (467 aa) |
| | argS | KEGG: mhu:Mhun_2837 arginyl-tRNA synthetase; TIGRFAM: arginyl-tRNA synthetase; Belongs to the class-I aminoacyl-tRNA synthetase family. (558 aa) |
| | sepS | O-phosphoseryl-tRNA(Cys) synthetase; Catalyzes the attachment of O-phosphoserine (Sep) to tRNA(Cys). (550 aa) |
| | Mboo_0280 | PFAM: glutamine amidotransferase class-I; KEGG: cya:CYA_0959 glutamine amidotransferase, class I. (218 aa) |
| | Mboo_0298 | PFAM: aminotransferase, class V; KEGG: mhu:Mhun_0255 aminotransferase, class V. (383 aa) |
| | Mboo_0356 | PFAM: aminotransferase, class V; aromatic amino acid beta-eliminating lyase/threonine aldolase; KEGG: gvi:gll4384 cysteine desulfurase. (390 aa) |
| | Mboo_0387 | PFAM: beta-lactamase domain protein; KEGG: hma:rrnAC3474 metallo-beta-lactamase superfamily protein. (231 aa) |
| | Mboo_0420 | TIGRFAM: cysteine synthases; cysteine synthase A; PFAM: Pyridoxal-5'-phosphate-dependent enzyme, beta subunit; KEGG: mba:Mbar_A2422 cysteine synthase. (311 aa) |
| | Mboo_0473 | KEGG: mhu:Mhun_1062 phosphoribosylformylglycinamidine synthase I. (277 aa) |
| | ilvC | Ketol-acid reductoisomerase; Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate. (329 aa) |
| | Mboo_0485 | PFAM: beta-lactamase domain protein; KEGG: mhu:Mhun_2337 beta-lactamase-like. (240 aa) |
| | Mboo_0492 | PFAM: Lactate/malate dehydrogenase; KEGG: mhu:Mhun_2343 L-lactate dehydrogenase; Belongs to the LDH/MDH superfamily. (332 aa) |
| | Mboo_0504 | PFAM: pyruvate ferredoxin/flavodoxin oxidoreductase; KEGG: mhu:Mhun_2359 pyruvate ferredoxin/flavodoxin oxidoreductase. (194 aa) |
| | Mboo_0514 | uroporphyrinogen-III synthase-like protein; Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III. (230 aa) |
| | Mboo_0598 | PFAM: pyruvate carboxyltransferase; KEGG: mhu:Mhun_1801 pyruvate carboxyltransferase; Belongs to the alpha-IPM synthase/homocitrate synthase family. (376 aa) |
| | Mboo_0599 | KEGG: mhu:Mhun_1800 3-isopropylmalate dehydratase; TIGRFAM: homoaconitate hydratase family protein; 3-isopropylmalate dehydratase; PFAM: aconitate hydratase domain protein. (403 aa) |
| | Mboo_0600 | TIGRFAM: 3-isopropylmalate dehydratase, small subunit; PFAM: aconitate hydratase domain protein; KEGG: mhu:Mhun_1799 3-isopropylmalate dehydratase, small subunit. (156 aa) |
| | Mboo_0602 | PFAM: isocitrate/isopropylmalate dehydrogenase; KEGG: mhu:Mhun_1797 3-isopropylmalate dehydrogenase. (325 aa) |
| | Mboo_0656 | tryptophanyl-tRNA synthetase; KEGG: mhu:Mhun_1732 tryptophan--tRNA ligase; TIGRFAM: tryptophanyl-tRNA synthetase; PFAM: aminoacyl-tRNA synthetase, class Ib. (418 aa) |
| | pheS | KEGG: mhu:Mhun_1729 phenylalanyl-tRNA synthetase, alpha subunit; TIGRFAM: phenylalanyl-tRNA synthetase, alpha subunit; PFAM: phenylalanyl-tRNA synthetase, class IIc; Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 2 subfamily. (498 aa) |
| | pheT | TIGRFAM: phenylalanyl-tRNA synthetase, beta subunit; PFAM: tRNA synthetase, B5; KEGG: mhu:Mhun_1728 phenylalanyl-tRNA synthetase, beta subunit. (542 aa) |
| | hisF | Imidazoleglycerol phosphate synthase, cyclase subunit; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit. (276 aa) |
| | Mboo_0672 | PFAM: thiamine pyrophosphate enzyme domain protein TPP-binding; KEGG: mhu:Mhun_0453 thiamine pyrophosphate enzyme-like TPP-binding. (299 aa) |
| | Mboo_0673 | PFAM: pyruvate flavodoxin/ferredoxin oxidoreductase domain protein; KEGG: mhu:Mhun_0452 pyruvate flavodoxin/ferredoxin oxidoreductase-like. (384 aa) |
| | Mboo_0674 | TIGRFAM: pyruvate ferredoxin/flavodoxin oxidoreductase, delta subunit; PFAM: 4Fe-4S ferredoxin, iron-sulfur binding domain protein; KEGG: mhu:Mhun_0451 2-oxoacid:acceptor oxidoreductase, delta subunit, pyruvate/2-ketoisovalerate. (86 aa) |
| | Mboo_0675 | KEGG: mhu:Mhun_0450 2-oxoacid:acceptor oxidoreductase, gamma subunit, pyruvate/2-ketoisovalerate; TIGRFAM: pyruvate/ketoisovalerate oxidoreductase, gamma subunit; PFAM: pyruvate ferredoxin/flavodoxin oxidoreductase. (181 aa) |
| | Mboo_0678 | Proposed homoserine kinase; KEGG: mhu:Mhun_0447 phosphonopyruvate decarboxylase-related protein; TIGRFAM: phosphonopyruvate decarboxylase-related protein; proposed homoserine kinase; PFAM: metalloenzyme domain protein. (383 aa) |
| | Mboo_0683 | Threonine synthase; Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine. (401 aa) |
| | guaAA | GMP synthase, small subunit; Catalyzes the synthesis of GMP from XMP. (184 aa) |
| | Mboo_0709 | KEGG: mhu:Mhun_1624 phenylacetate--CoA ligase. (433 aa) |
| | Mboo_0710 | KEGG: mhu:Mhun_1625 phenylacetate--CoA ligase. (423 aa) |
| | Mboo_0728 | PFAM: pyruvate ferredoxin/flavodoxin oxidoreductase; KEGG: mhu:Mhun_0094 2-oxoacid:acceptor oxidoreductase, gamma subunit, pyruvate/2-ketoisovalerate. (178 aa) |
| | argH | TIGRFAM: argininosuccinate lyase; PFAM: fumarate lyase; KEGG: mhu:Mhun_0084 argininosuccinate lyase. (474 aa) |
| | gatD | glutamyl-tRNA(Gln) amidotransferase, subunit D; Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu- tRNA(Gln). The GatDE system is specific for glutamate and does not act on aspartate. (382 aa) |
| | Mboo_0767 | PFAM: purine phosphorylase, family 2; KEGG: mhu:Mhun_1049 purine phosphorylase, family 2. (223 aa) |
| | Mboo_0780 | PFAM: beta-lactamase domain protein; KEGG: gsu:GSU2769 metallo-beta-lactamase family protein. (287 aa) |
| | Mboo_0814 | TIGRFAM: glycyl-tRNA synthetase; PFAM: tRNA synthetase, class II (G, H, P and S); Anticodon-binding domain protein; KEGG: mhu:Mhun_1707 glycyl-tRNA synthetase. (573 aa) |
| | metG | methionyl-tRNA synthetase; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation. (662 aa) |
| | carA | TIGRFAM: carbamoyl-phosphate synthase, small subunit; PFAM: glutamine amidotransferase class-I; Carbamoyl-phosphate synthase, small chain; KEGG: mhu:Mhun_0114 carbamoyl-phosphate synthase, small subunit; Belongs to the CarA family. (354 aa) |
| | carB | TIGRFAM: carbamoyl-phosphate synthase, large subunit; PFAM: ATP-dependent carboxylate-amine ligase domain protein, ATP-grasp; protein of unknown function DUF201; Carbamoyl-phosphate synthase L chain, ATP-binding; Carbamoyl-phosphate synthetase large chain, oligomerisation; Carbamoyl-phosphate synthetase large chain domain protein; MGS domain protein; KEGG: mhu:Mhun_0115 carbamoyl-phosphate synthase, large subunit. (1053 aa) |
| | argG | PFAM: argininosuccinate synthase; ExsB family protein; KEGG: mhu:Mhun_0116 argininosuccinate synthase; Belongs to the argininosuccinate synthase family. Type 1 subfamily. (403 aa) |
| | argF | KEGG: mba:Mbar_A3512 ornithine carbamoyltransferase; TIGRFAM: ornithine carbamoyltransferase; PFAM: aspartate/ornithine carbamoyltransferase, Asp/Orn-binding region; aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain. (303 aa) |
| | ala | Ornithine cyclodeaminase; Catalyzes the NAD(+)-dependent oxidative deamination of L- alanine to pyruvate, and the reverse reaction, the reductive amination of pyruvate; Belongs to the ornithine cyclodeaminase/mu-crystallin family. Archaeal alanine dehydrogenase subfamily. (311 aa) |
| | Mboo_0855 | PFAM: asparagine synthase; KEGG: mhu:Mhun_1015 asparagine synthase. (334 aa) |
| | Mboo_0864 | TIGRFAM: putative CoA-substrate-specific enzyme activase; PFAM: ATPase, BadF/BadG/BcrA/BcrD type; KEGG: sat:SYN_00371 activator of D-2-hydroxyacyl-CoA dehydratase. (249 aa) |
| | Mboo_0880 | PFAM: beta-lactamase domain protein; KEGG: mac:MA1946 dihydropteroate synthase. (322 aa) |
| | thrS | threonyl-tRNA synthetase; Catalyzes the attachment of threonine to tRNA(Thr) in a two- step reaction: L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr). Also edits incorrectly charged L-seryl-tRNA(Thr); Belongs to the class-II aminoacyl-tRNA synthetase family. (614 aa) |
| | Mboo_0915 | TIGRFAM: acetate--CoA ligase; PFAM: AMP-dependent synthetase and ligase; KEGG: mbu:Mbur_1137 acetate--CoA ligase. (631 aa) |
| | Mboo_0923 | PFAM: molybdopterin oxidoreductase; molydopterin dinucleotide-binding region; molybdopterin oxidoreductase Fe4S4 region; KEGG: mba:Mbar_A1561 formate dehydrogenase alpha subunit. (621 aa) |
| | Mboo_0932 | Enolase; KEGG: deh:cbdb_A573 enolase. (55 aa) |
| | Mboo_0991 | PFAM: glutamine amidotransferase class-I; CobB/CobQ domain protein glutamine amidotransferase; KEGG: mtp:Mthe_1351 glutamine amidotransferase class-I. (186 aa) |
| | Mboo_1046 | PFAM: Orn/DAP/Arg decarboxylase 2; KEGG: diaminopimelate decarboxylase. (397 aa) |
| | hisG-2 | ATP phosphoribosyltransferase; Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity. Belongs to the ATP phosphoribosyltransferase family. Long subfamily. (285 aa) |
| | hisA | TIGRFAM: phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase; PFAM: histidine biosynthesis; KEGG: mhu:Mhun_0921 histidine biosynthesis. (236 aa) |
| | hisB | PFAM: imidazoleglycerol-phosphate dehydratase; KEGG: sth:STH2836 imidazoleglycerol-phosphate dehydratase. (192 aa) |
| | Mboo_1080 | PFAM: beta-lactamase domain protein; KEGG: bur:Bcep18194_B3119 beta-lactamase-like. (294 aa) |
| | Mboo_1109 | PFAM: Lactate/malate dehydrogenase; KEGG: mhu:Mhun_1155 lactate/malate dehydrogenase; Belongs to the LDH/MDH superfamily. (288 aa) |
| | Mboo_1115 | 2-dehydropantoate 2-reductase; Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid. (309 aa) |
| | Mboo_1125 | KEGG: mma:MM1061 hydrogenase-4 component E. (230 aa) |
| | Mboo_1175 | TIGRFAM: HAD-superfamily hydrolase, subfamily IA, variant 3; HAD-superfamily hydrolase, subfamily IA, variant 1; PFAM: Haloacid dehalogenase domain protein hydrolase; KEGG: mma:MM2349 putative phosphatase. (241 aa) |
| | pdaD | KEGG: mhu:Mhun_0113 arginine decarboxylase; TIGRFAM: arginine decarboxylase, pyruvoyl-dependent; PFAM: Pyruvoyl-dependent arginine decarboxylase; Belongs to the PdaD family. (180 aa) |
| | ilvD | KEGG: mhu:Mhun_0139 dihydroxy-acid dehydratase; TIGRFAM: dihydroxy-acid dehydratase; PFAM: dihydroxy-acid and 6-phosphogluconate dehydratase; Belongs to the IlvD/Edd family. (550 aa) |
| | Mboo_1251 | PFAM: beta-lactamase domain protein; KEGG: mhu:Mhun_0123 beta-lactamase-like. (196 aa) |
| | Mboo_1256 | PFAM: shikimate kinase; KEGG: mhu:Mhun_1850 shikimate kinase. (166 aa) |
| | hisH | Imidazole glycerol phosphate synthase, glutamine amidotransferase subunit; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF. (202 aa) |
| | alaS | alanyl-tRNA synthetase; Catalyzes the attachment of alanine to tRNA(Ala) in a two- step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain. (914 aa) |
| | Mboo_1272 | PFAM: CBS domain containing protein; protein of unknown function DUF39; KEGG: mhu:Mhun_0138 protein of unknown function DUF39. (502 aa) |
| | Mboo_1273 | PFAM: 4Fe-4S ferredoxin, iron-sulfur binding domain protein; KEGG: mhu:Mhun_0137 4Fe-4S ferredoxin, iron-sulfur binding. (128 aa) |
| | Mboo_1283 | PFAM: glyceraldehyde 3-phosphate dehydrogenase; KEGG: cya:CYA_0020 glyceraldehyde-3-phosphate dehydrogenase, type I; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family. (323 aa) |
| | Mboo_1287 | PFAM: beta-lactamase domain protein; KEGG: mhu:Mhun_0673 beta-lactamase-like. (226 aa) |
| | Mboo_1307 | PFAM: aldehyde dehydrogenase; KEGG: mma:MM0838 succinate-semialdehyde dehydrogenase [NADP+]. (476 aa) |
| | Mboo_1315 | NAD(P)(+) transhydrogenase (AB-specific); PFAM: alanine dehydrogenase/PNT domain protein; KEGG: aeh:Mlg_2771 NAD(P)(+) transhydrogenase (AB-specific). (381 aa) |
| | Mboo_1354 | PFAM: homoserine dehydrogenase; homoserine dehydrogenase, NAD-binding; KEGG: mhu:Mhun_2292 homoserine dehydrogenase. (328 aa) |
| | Mboo_1356 | PFAM: glutamine amidotransferase class-I; KEGG: cya:CYA_0959 glutamine amidotransferase, class I. (233 aa) |
| | Mboo_1380 | TIGRFAM: F420-dependent oxidoreductase, putative; PFAM: protein of unknown function DUF129; KEGG: mhu:Mhun_0850 uncharacterised conserved protein UCP005026. (227 aa) |
| | Mboo_1388 | TIGRFAM: acetylornithine deacetylase or succinyl-diaminopimelate desuccinylase; PFAM: peptidase M20; peptidase dimerisation domain protein; KEGG: mhu:Mhun_1484 peptidase M20. (393 aa) |
| | dapA | Dihydrodipicolinate synthase; Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA). (313 aa) |
| | dapB | Dihydrodipicolinate reductase; Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate. (255 aa) |
| | Mboo_1399 | TIGRFAM: aspartate-semialdehyde dehydrogenase; PFAM: Semialdehyde dehydrogenase, NAD - binding; Semialdehyde dehydrogenase, dimerisation region; KEGG: mhu:Mhun_1495 aspartate-semialdehyde dehydrogenase. (338 aa) |
| | Mboo_1403 | KEGG: mhu:Mhun_0943 putative phosphoserine phosphatase. (286 aa) |
| | cbiA-2 | Cobyrinic acid a,c-diamide synthase; Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source. Involved in the biosynthesis of the unique nickel-containing tetrapyrrole coenzyme F430, the prosthetic group of methyl-coenzyme M reductase (MCR), which plays a key role in methanogenesis and anaerobic methane oxidation. Catalyzes the ATP- dependent amidation of the two carboxylate groups at positions a and c of Ni-sirohydrochlorin, using L-glutamine or ammonia as the nitrogen source. (457 aa) |
| | ilvE | Branched-chain amino acid aminotransferase; Acts on leucine, isoleucine and valine. Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family. (347 aa) |
| | serS | seryl-tRNA synthetase; Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L- seryl-tRNA(Sec), which will be further converted into selenocysteinyl- tRNA(Sec). (425 aa) |
| | cimA | Isopropylmalate/citramalate/homocitrate synthase; Catalyzes the condensation of pyruvate and acetyl-coenzyme A to form (R)-citramalate; Belongs to the alpha-IPM synthase/homocitrate synthase family. (496 aa) |
| | Mboo_1444 | TIGRFAM: acetolactate synthase, small subunit; PFAM: amino acid-binding ACT domain protein; KEGG: mhu:Mhun_1241 acetolactate synthase, small subunit. (167 aa) |
| | gpmA | Phosphoglycerate mutase 1 family; Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate. (249 aa) |
| | Mboo_1457 | PFAM: protein of unknown function DUF126; KEGG: mhu:Mhun_1041 protein of unknown function DUF126; Belongs to the UPF0107 family. (146 aa) |
| | Mboo_1525 | PFAM: ADP-specific phosphofructokinase/glucokinase; KEGG: pab:PAB0967 ADP-specific glucokinase. (417 aa) |
| | pgk | PFAM: phosphoglycerate kinase; KEGG: tte:TTE1761 3-phosphoglycerate kinase; Belongs to the phosphoglycerate kinase family. (395 aa) |
| | aroA | Predicted phospho-2-dehydro-3-deoxyheptonate aldolase; Catalyzes a transaldol reaction between 6-deoxy-5- ketofructose 1-phosphate (DKFP) and L-aspartate semialdehyde (ASA) with an elimination of hydroxypyruvaldehyde phosphate to yield 2-amino-3,7- dideoxy-D-threo-hept-6-ulosonate (ADH). Plays a key role in an alternative pathway of the biosynthesis of 3-dehydroquinate (DHQ), which is involved in the canonical pathway for the biosynthesis of aromatic amino acids. (262 aa) |
| | aroA-2 | Predicted phospho-2-dehydro-3-deoxyheptonate aldolase; Catalyzes a transaldol reaction between 6-deoxy-5- ketofructose 1-phosphate (DKFP) and L-aspartate semialdehyde (ASA) with an elimination of hydroxypyruvaldehyde phosphate to yield 2-amino-3,7- dideoxy-D-threo-hept-6-ulosonate (ADH). Plays a key role in an alternative pathway of the biosynthesis of 3-dehydroquinate (DHQ), which is involved in the canonical pathway for the biosynthesis of aromatic amino acids. (260 aa) |
| | aroB | 3-dehydroquinate synthase; Catalyzes the oxidative deamination and cyclization of 2- amino-3,7-dideoxy-D-threo-hept-6-ulosonic acid (ADH) to yield 3- dehydroquinate (DHQ), which is fed into the canonical shikimic pathway of aromatic amino acid biosynthesis; Belongs to the archaeal-type DHQ synthase family. (329 aa) |
| | Mboo_1560 | PFAM: Prephenate dehydrogenase; KEGG: mhu:Mhun_1033 prephenate dehydrogenase. (276 aa) |
| | Mboo_1561 | PFAM: prephenate dehydratase; amino acid-binding ACT domain protein; KEGG: mhu:Mhun_1032 prephenate dehydratase. (264 aa) |
| | aroA-3 | 3-phosphoshikimate 1-carboxyvinyltransferase; Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate. (421 aa) |
| | aroE | Shikimate 5-dehydrogenase; Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA). (462 aa) |
| | aroC | Chorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system. (328 aa) |
| | Mboo_1569 | PFAM: beta-lactamase domain protein; KEGG: mac:MA1946 dihydropteroate synthase. (312 aa) |
| | aroD | Dehydroquinase class I; Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis- dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3-dehydroshikimate. Belongs to the type-I 3-dehydroquinase family. (209 aa) |
| | tpiA | Triosephosphate isomerase; Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P); Belongs to the triosephosphate isomerase family. (229 aa) |
| | Mboo_1611 | KEGG: mbu:Mbur_1969 fructose-bisphosphate aldolase, class-II, putative. (379 aa) |
| | Mboo_1626 | PFAM: RimK domain protein ATP-grasp; KEGG: mtp:Mthe_1695 RimK domain protein ATP-grasp. (290 aa) |
| | Mboo_1667 | TIGRFAM: phosphopantothenoylcysteine decarboxylase/phosphopantothenate--cysteine ligase; PFAM: flavoprotein; DNA/pantothenate metabolism flavoprotein domain protein; KEGG: mhu:Mhun_0830 phosphopantothenoylcysteine decarboxylase/phosphopantothenate--cysteine ligase. (397 aa) |
| | Mboo_1681 | PFAM: AMP-dependent synthetase and ligase; KEGG: mhu:Mhun_0592 AMP-dependent synthetase and ligase. (555 aa) |
| | Mboo_1682 | PFAM: AMP-dependent synthetase and ligase; KEGG: mhu:Mhun_2392 AMP-dependent synthetase and ligase. (609 aa) |
| | Mboo_1689 | KEGG: mhu:Mhun_0779 glutamine synthetase, type I; TIGRFAM: glutamine synthetase, type I; PFAM: glutamine synthetase, catalytic region; glutamine synthetase, beta-Grasp. (441 aa) |
| | Mboo_1690 | PFAM: glutamine amidotransferase, class-II; KEGG: mhu:Mhun_0780 glutamine amidotransferase, class-II. (349 aa) |
| | Mboo_1691 | Glutamate synthase (NADPH); PFAM: dihydroorotate dehydrogenase; 4Fe-4S ferredoxin, iron-sulfur binding domain protein; ferredoxin-dependent glutamate synthase; KEGG: mhu:Mhun_0781 glutamate synthase (NADPH); Belongs to the glutamate synthase family. (503 aa) |
| | Mboo_1718 | PFAM: histidine biosynthesis; KEGG: mhu:Mhun_2630 histidine biosynthesis; Belongs to the HisA/HisF family. (238 aa) |
| | valS | valyl-tRNA synthetase; Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA- dependent manner; Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 2 subfamily. (864 aa) |
| | hisS | KEGG: mhu:Mhun_2918 histidyl-tRNA synthetase; TIGRFAM: histidyl-tRNA synthetase; PFAM: tRNA synthetase, class II (G, H, P and S); Anticodon-binding domain protein; Belongs to the class-II aminoacyl-tRNA synthetase family. (410 aa) |
| | Mboo_1740 | TIGRFAM: holo-acyl-carrier-protein synthase; PFAM: 4'-phosphopantetheinyl transferase; KEGG: mhu:Mhun_3109 phosphopantethiene--protein transferase domain. (151 aa) |
| | Mboo_1743 | PFAM: acyl-protein synthetase, LuxE; KEGG: mhu:Mhun_3112 acyl-protein synthetase, LuxE. (376 aa) |
| | Mboo_1764 | UDP-glucose 6-dehydrogenase; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; UDP-glucose/GDP-mannose dehydrogenase; KEGG: mhu:Mhun_3078 UDP-glucose 6-dehydrogenase. (425 aa) |
| | Mboo_1815 | PFAM: pyruvate carboxyltransferase; LeuA allosteric (dimerisation) domain; KEGG: mhu:Mhun_2360 pyruvate carboxyltransferase; Belongs to the alpha-IPM synthase/homocitrate synthase family. (490 aa) |
| | Mboo_1840 | Putative translation initiation factor, aIF-2BI family; Catalyzes the interconversion of methylthioribose-1-phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P). Belongs to the EIF-2B alpha/beta/delta subunits family. MtnA subfamily. (348 aa) |
| | cobQ | Cobyric acid synthase CobQ; Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation. Belongs to the CobB/CobQ family. CobQ subfamily. (480 aa) |
| | hisI | Phosphoribosyl-AMP cyclohydrolase; Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP. (123 aa) |
| | leuS | TIGRFAM: leucyl-tRNA synthetase; KEGG: mhu:Mhun_2923 leucyl-tRNA synthetase; Belongs to the class-I aminoacyl-tRNA synthetase family. (926 aa) |
| | pfkA | 6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis; Belongs to the phosphofructokinase type A (PFKA) family. Mixed-substrate PFK group III subfamily. (351 aa) |
| | Mboo_1947 | KEGG: rso:RSp0886 probable glutamine synthetase protein; TIGRFAM: glutamine synthetase, type I; PFAM: glutamine synthetase, catalytic region; glutamine synthetase, beta-Grasp. (491 aa) |
| | proS | prolyl-tRNA synthetase; Catalyzes the attachment of proline to tRNA(Pro) in a two- step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro). (478 aa) |
| | Mboo_1982 | KEGG: mac:MA2721 serine O-acetyltransferase / hypothetical protein (multi-domain); TIGRFAM: serine O-acetyltransferase; PFAM: transferase hexapeptide repeat containing protein; protein of unknown function DUF59. (320 aa) |
| | Mboo_1983 | TIGRFAM: cysteine synthases; cysteine synthase A; PFAM: Pyridoxal-5'-phosphate-dependent enzyme, beta subunit; KEGG: mba:Mbar_A2422 cysteine synthase. (309 aa) |
| | Mboo_1984 | PFAM: aminotransferase, class V; aromatic amino acid beta-eliminating lyase/threonine aldolase; KEGG: mhu:Mhun_2219 phosphoadenosine phosphosulfate reductase. (394 aa) |
| | Mboo_1990 | PFAM: Pyridoxal-5'-phosphate-dependent enzyme, beta subunit; KEGG: ava:Ava_4156 cystathionine beta-synthase. (326 aa) |
| | Mboo_1991 | Cystathionine gamma-lyase; PFAM: aminotransferase, class V; Cys/Met metabolism pyridoxal-phosphate-dependent enzymes; aromatic amino acid beta-eliminating lyase/threonine aldolase; KEGG: cystathionine gamma-lyase. (386 aa) |
| | cysS | KEGG: mhu:Mhun_2176 cysteinyl-tRNA synthetase; TIGRFAM: cysteinyl-tRNA synthetase; PFAM: cysteinyl-tRNA synthetase, class Ia; Belongs to the class-I aminoacyl-tRNA synthetase family. (419 aa) |
| | Mboo_1994 | KEGG: mhu:Mhun_2181 O-acetylhomoserine/O-acetylserine sulfhydrylase; TIGRFAM: O-acetylhomoserine/O-acetylserine sulfhydrylase; PFAM: Cys/Met metabolism pyridoxal-phosphate-dependent enzymes; DegT/DnrJ/EryC1/StrS aminotransferase. (467 aa) |
| | Mboo_1995 | PFAM: aminotransferase, class V; Cys/Met metabolism pyridoxal-phosphate-dependent enzymes; aromatic amino acid beta-eliminating lyase/threonine aldolase; KEGG: sil:SPO0413 Cys/Met metabolism PLP-dependent enzyme family protein. (403 aa) |
| | Mboo_2020 | PFAM: D-isomer specific 2-hydroxyacid dehydrogenase, catalytic region; D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding; KEGG: ath:At1g72190 oxidoreductase family protein. (325 aa) |
| | Mboo_2033 | KEGG: sfu:Sfum_0182 hypothetical protein. (136 aa) |
| | metXA | Homoserine O-acetyltransferase; Transfers an acetyl group from acetyl-CoA to L-homoserine, forming acetyl-L-homoserine. (491 aa) |
| | Mboo_2044 | KEGG: mhu:Mhun_2181 O-acetylhomoserine/O-acetylserine sulfhydrylase; TIGRFAM: O-acetylhomoserine/O-acetylserine sulfhydrylase; PFAM: Cys/Met metabolism pyridoxal-phosphate-dependent enzymes; DegT/DnrJ/EryC1/StrS aminotransferase. (431 aa) |
| | hisE | PFAM: MazG nucleotide pyrophosphohydrolase; phosphoribosyl-ATP pyrophosphohydrolase; KEGG: mhu:Mhun_0790 phosphoribosyl-ATP pyrophosphohydrolase. (104 aa) |
| | leuC | 3-isopropylmalate dehydratase; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. (416 aa) |
| | leuD | 3-isopropylmalate dehydratase, small subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. Belongs to the LeuD family. LeuD type 2 subfamily. (165 aa) |
| | Mboo_2077 | PFAM: isocitrate/isopropylmalate dehydrogenase; KEGG: mhu:Mhun_2363 3-isopropylmalate dehydrogenase. (371 aa) |
| | Mboo_2096 | PFAM: aminotransferase, class I and II; KEGG: mhu:Mhun_2943 aminotransferase, class I and II. (382 aa) |
| | lysA | Diaminopimelate decarboxylase; Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine. (430 aa) |
| | nadA | Quinolinate synthetase complex, A subunit; Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate. (302 aa) |
| | iscS | Aminotransferase, class V; Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins. (398 aa) |
| | hisC | PFAM: aminotransferase, class I and II; KEGG: mhu:Mhun_2525 histidinol-phosphate aminotransferase. (351 aa) |
| | Mboo_2138 | TIGRFAM: acetylornithine and succinylornithine aminotransferases; PFAM: aminotransferase class-III; KEGG: mhu:Mhun_2526 acetylornithine and succinylornithine aminotransferases; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (383 aa) |
| | pyrG | CTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates. (526 aa) |
| | hisD | Histidinol dehydrogenase; Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine. (426 aa) |
| | Mboo_2164 | TIGRFAM: D-3-phosphoglycerate dehydrogenase; PFAM: amino acid-binding ACT domain protein; D-isomer specific 2-hydroxyacid dehydrogenase, catalytic region; D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding; KEGG: mhu:Mhun_3063 D-3-phosphoglycerate dehydrogenase. (534 aa) |
| | Mboo_2165 | Phosphoenolpyruvate synthase; Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate; Belongs to the PEP-utilizing enzyme family. (761 aa) |
| | mfnA | Pyridoxal-dependent decarboxylase; Catalyzes the decarboxylation of L-tyrosine to produce tyramine for methanofuran biosynthesis. Can also catalyze the decarboxylation of L-aspartate to produce beta-alanine for coenzyme A (CoA) biosynthesis; Belongs to the group II decarboxylase family. MfnA subfamily. (365 aa) |
| | glyA | Glycine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. Also exhibits THF-independent aldolase activity toward beta- hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. (417 aa) |
| | folD | Methenyltetrahydrofolate cyclohydrolase; Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate. (278 aa) |
| | Mboo_2190 | TIGRFAM: F420-dependent oxidoreductase, putative; PFAM: protein of unknown function DUF129; KEGG: mhu:Mhun_0020 uncharacterised conserved protein UCP005026. (256 aa) |
| | cofC | Protein of unknown function DUF121; Guanylyltransferase that catalyzes the activation of phosphoenolpyruvate (PEP) as enolpyruvoyl-2-diphospho-5'-guanosine, via the condensation of PEP with GTP. It is involved in the biosynthesis of coenzyme F420, a hydride carrier cofactor; Belongs to the CofC family. (214 aa) |
| | gltX | glutamyl-tRNA synthetase; Catalyzes the attachment of glutamate to tRNA(Glu) in a two- step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu). (634 aa) |
| | eno | Phosphopyruvate hydratase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family. (395 aa) |
| | dtdA | Protein of unknown function DUF516; D-aminoacyl-tRNA deacylase with broad substrate specificity. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo. (458 aa) |
| | ileS | isoleucyl-tRNA synthetase; Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile). Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 2 subfamily. (1076 aa) |
| | Mboo_2314 | PFAM: protein of unknown function DUF1271; SMART: zinc finger, CDGSH-type domain protein; KEGG: mba:Mbar_A3576 hypothetical protein. (232 aa) |
| | Mboo_2325 | PFAM: glucose-6-phosphate isomerase; KEGG: mhu:Mhun_2600 putative glucose-6-phosphate isomerase. (237 aa) |
| | lysS | TIGRFAM: lysyl-tRNA synthetase; PFAM: tRNA synthetase, class II (D, K and N); nucleic acid binding, OB-fold, tRNA/helicase-type; KEGG: mhu:Mhun_2496 lysyl-tRNA synthetase; Belongs to the class-II aminoacyl-tRNA synthetase family. (514 aa) |
| | pgk-2 | PFAM: phosphoglycerate kinase; KEGG: mhu:Mhun_1194 phosphoglycerate kinase; Belongs to the phosphoglycerate kinase family. (404 aa) |
| | dapF | Diaminopimelate epimerase; Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L- lysine. (275 aa) |
| | Mboo_2438 | TIGRFAM: putative CoA-substrate-specific enzyme activase; PFAM: ATPase, BadF/BadG/BcrA/BcrD type; KEGG: mhu:Mhun_2307 CoA enzyme activase. (417 aa) |
| | Mboo_2442 | KEGG: pab:PAB1605 asparagine synthase (glutamine-hydrolysing); TIGRFAM: asparagine synthase (glutamine-hydrolyzing); PFAM: glutamine amidotransferase, class-II; asparagine synthase. (607 aa) |
| | gap | KEGG: mhu:Mhun_2462 glyceraldehyde-3-phosphate dehydrogenase, type II; TIGRFAM: glyceraldehyde-3-phosphate dehydrogenase, type II; PFAM: glyceraldehyde 3-phosphate dehydrogenase; dihydrodipicolinate reductase. (343 aa) |
