STRINGSTRING
purA purA Mboo_0056 Mboo_0056 purF purF glmS glmS Mboo_0473 Mboo_0473 argH argH carA carA carB carB argG argG ala ala Mboo_0855 Mboo_0855 Mboo_1118 Mboo_1118 Mboo_1200 Mboo_1200 Mboo_1689 Mboo_1689 pyrI pyrI Mboo_1947 Mboo_1947 Mboo_2031 Mboo_2031 Mboo_2442 Mboo_2442
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
purAAdenylosuccinate synthase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family. (337 aa)
Mboo_0056PFAM: aminotransferase, class I and II; KEGG: mhu:Mhun_2478 aminotransferase, class I and II. (379 aa)
purFAmidophosphoribosyltransferase; Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine. (476 aa)
glmSGlucosamine--fructose-6-phosphate aminotransferase, isomerizing; Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source. (580 aa)
Mboo_0473KEGG: mhu:Mhun_1062 phosphoribosylformylglycinamidine synthase I. (277 aa)
argHTIGRFAM: argininosuccinate lyase; PFAM: fumarate lyase; KEGG: mhu:Mhun_0084 argininosuccinate lyase. (474 aa)
carATIGRFAM: carbamoyl-phosphate synthase, small subunit; PFAM: glutamine amidotransferase class-I; Carbamoyl-phosphate synthase, small chain; KEGG: mhu:Mhun_0114 carbamoyl-phosphate synthase, small subunit; Belongs to the CarA family. (354 aa)
carBTIGRFAM: carbamoyl-phosphate synthase, large subunit; PFAM: ATP-dependent carboxylate-amine ligase domain protein, ATP-grasp; protein of unknown function DUF201; Carbamoyl-phosphate synthase L chain, ATP-binding; Carbamoyl-phosphate synthetase large chain, oligomerisation; Carbamoyl-phosphate synthetase large chain domain protein; MGS domain protein; KEGG: mhu:Mhun_0115 carbamoyl-phosphate synthase, large subunit. (1053 aa)
argGPFAM: argininosuccinate synthase; ExsB family protein; KEGG: mhu:Mhun_0116 argininosuccinate synthase; Belongs to the argininosuccinate synthase family. Type 1 subfamily. (403 aa)
alaOrnithine cyclodeaminase; Catalyzes the NAD(+)-dependent oxidative deamination of L- alanine to pyruvate, and the reverse reaction, the reductive amination of pyruvate; Belongs to the ornithine cyclodeaminase/mu-crystallin family. Archaeal alanine dehydrogenase subfamily. (311 aa)
Mboo_0855PFAM: asparagine synthase; KEGG: mhu:Mhun_1015 asparagine synthase. (334 aa)
Mboo_1118TIGRFAM: adenylosuccinate lyase; PFAM: fumarate lyase; KEGG: mhu:Mhun_0824 adenylosuccinate lyase; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. (446 aa)
Mboo_1200PFAM: aminotransferase, class I and II; KEGG: mhu:Mhun_0911 aminotransferase, class I and II. (371 aa)
Mboo_1689KEGG: mhu:Mhun_0779 glutamine synthetase, type I; TIGRFAM: glutamine synthetase, type I; PFAM: glutamine synthetase, catalytic region; glutamine synthetase, beta-Grasp. (441 aa)
pyrIAspartate carbamoyltransferase, regulatory subunit; Involved in allosteric regulation of aspartate carbamoyltransferase. (165 aa)
Mboo_1947KEGG: rso:RSp0886 probable glutamine synthetase protein; TIGRFAM: glutamine synthetase, type I; PFAM: glutamine synthetase, catalytic region; glutamine synthetase, beta-Grasp. (491 aa)
Mboo_2031TIGRFAM: aspartate racemase; PFAM: Asp/Glu racemase; KEGG: eca:ECA1293 putative aspartate/glutamate racemase. (240 aa)
Mboo_2442KEGG: pab:PAB1605 asparagine synthase (glutamine-hydrolysing); TIGRFAM: asparagine synthase (glutamine-hydrolyzing); PFAM: glutamine amidotransferase, class-II; asparagine synthase. (607 aa)
Your Current Organism:
Methanoregula boonei
NCBI taxonomy Id: 456442
Other names: Candidatus Methanoregula boonei 6A8, M. boonei 6A8, Methanoregula boonei 6A8, Methanoregula boonei str. 6A8, Methanoregula boonei strain 6A8, methanogenic archaeon 6A8
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