STRINGSTRING
fadB1 fadB1 leuC1 leuC1 hemB hemB ABZ96199.1 ABZ96199.1 ABZ96255.1 ABZ96255.1 gmd gmd ptpS ptpS ABZ96469.1 ABZ96469.1 ABZ96481.1 ABZ96481.1 dapA dapA ABZ96946.1 ABZ96946.1 ABZ96995.1 ABZ96995.1 hisB hisB crt crt ABZ99802.1 ABZ99802.1 acnA acnA mtnB mtnB aroD aroD ilvD ilvD fadB3 fadB3 fumA fumA fumC fumC ABZ99178.1 ABZ99178.1 trpB trpB trpA trpA rmlB rmlB ABZ97892.1 ABZ97892.1 mqnA mqnA eno eno leuD2 leuD2 leuC2 leuC2 ABZ97658.1 ABZ97658.1 ABZ97628.1 ABZ97628.1 leuD1 leuD1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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fadB1Enoyl-CoA hydratase; Function of homologous gene experimentally demonstrated in an other organism; enzyme. (277 aa)
leuC13-isopropylmalate dehydratase large subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. (467 aa)
hemBDelta-aminolevulinic acid dehydratase; Porphobilinogen synthase; ALAD; ALADH); Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the ALAD family. (317 aa)
ABZ96199.1Putative enoyl-CoA hydratase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme; Belongs to the enoyl-CoA hydratase/isomerase family. (260 aa)
ABZ96255.1Putative enoyl-CoA hydratase/carnithine racemase; Function of homologous gene experimentally demonstrated in an other organism; enzyme. (261 aa)
gmdGDP-mannose 4,6-dehydratase; Catalyzes the conversion of GDP-D-mannose to GDP-4-dehydro-6- deoxy-D-mannose. (338 aa)
ptpS6-pyruvoyl tetrahydrobiopterin synthase; Function of homologous gene experimentally demonstrated in an other organism; enzyme. (124 aa)
ABZ96469.1Conserved hypothetical protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology. (319 aa)
ABZ96481.1Enoyl-CoA hydratase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the enoyl-CoA hydratase/isomerase family. (245 aa)
dapADihydrodipicolinate synthase (DHDPS); Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA). (294 aa)
ABZ96946.1Putative pterin-4-alpha-carbinolamine dehydratase; PHS; 4-alpha-hydroxy-tetrahydropterin dehydratase; Pterin carbinolamine dehydratase; PCD; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. (102 aa)
ABZ96995.1Enoyl-CoA hydratase (Enoyl hydrase; Function of homologous gene experimentally demonstrated in an other organism; enzyme. (272 aa)
hisBImidazoleglycerol-phosphate dehydratase (IGPD); Function of homologous gene experimentally demonstrated in an other organism; enzyme. (197 aa)
crt3-hydroxybutyryl-CoA dehydratase (Crotonase); Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the enoyl-CoA hydratase/isomerase family. (254 aa)
ABZ99802.1Putative beta-type carbonic anhydrase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; enzyme. (226 aa)
acnAAconitate hydratase; Function of homologous gene experimentally demonstrated in an other organism; enzyme. (751 aa)
mtnBPutative class II aldolase/adducin domain protein; Catalyzes the dehydration of methylthioribulose-1-phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P). Belongs to the aldolase class II family. MtnB subfamily. (209 aa)
aroD3-dehydroquinate dehydratase; Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis- dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3-dehydroshikimate. Belongs to the type-I 3-dehydroquinase family. (238 aa)
ilvDDihydroxy-acid dehydratase (DAD); Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the IlvD/Edd family. (558 aa)
fadB33-hydroxyacyl-CoA dehydrogenase, NAD binding FadB; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the enoyl-CoA hydratase/isomerase family. (257 aa)
fumAFumarate hydratase class I, aerobic (Fumarase); Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family. (537 aa)
fumCFumarate hydratase class II (Fumarase C); Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily. (462 aa)
ABZ99178.1Putative 6-pyruvoyl tetrahydrobiopterin synthase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. (134 aa)
trpBTryptophan synthase beta chain; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine. (396 aa)
trpATryptophan synthase alpha protein; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family. (266 aa)
rmlBdTDP-glucose 4,6-dehydratase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the NAD(P)-dependent epimerase/dehydratase family. dTDP-glucose dehydratase subfamily. (340 aa)
ABZ97892.1Putative enoyl-CoA hydratase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. (252 aa)
mqnAConserved hypothetical protein; Catalyzes the dehydration of chorismate into 3-[(1- carboxyvinyl)oxy]benzoate, a step in the biosynthesis of menaquinone (MK, vitamin K2). (248 aa)
enoEnolase (2-phosphoglycerate dehydratase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family. (433 aa)
leuD23-isopropylmalate dehydratase small subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. Belongs to the LeuD family. LeuD type 1 subfamily. (208 aa)
leuC23-isopropylmalate dehydratase large subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. (464 aa)
ABZ97658.1Putative L-fuculose-phosphate aldolase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. (218 aa)
ABZ97628.1Hypothetical protein; Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. In the C-terminal section; belongs to the NnrD/CARKD family. (502 aa)
leuD13-isopropylmalate dehydratase small subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. Belongs to the LeuD family. LeuD type 1 subfamily. (208 aa)
Your Current Organism:
Leptospira biflexa
NCBI taxonomy Id: 456481
Other names: L. biflexa serovar Patoc strain 'Patoc 1 (Paris)', Leptospira biflexa serovar Patoc str. ATCC 23582, Leptospira biflexa serovar Patoc strain 'Patoc 1 (Paris)', Leptospira biflexa serovar Patoc strain Patoc 1
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