Your Input: | |
| | pyrB | Aspartate carbamoyltransferase, catalytic subunit (Aspartate transcarbamylase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family. (310 aa) |
| | ABZ97133.1 | Conserved hypothetical protein; Homologs of previously reported genes of unknown function. (317 aa) |
| | glyA | Serine hydroxymethyltransferase (Serine methylase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. (416 aa) |
| | ABZ97095.1 | Putative beta-lactamase II (Penicillinase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. (274 aa) |
| | hisE | Phosphoribosyl-ATP pyrophosphatase (PRA-PH); Function of homologous gene experimentally demonstrated in an other organism; enzyme. (92 aa) |
| | ugd | UDP-glucose 6-dehydrogenase (UDP-Glc dehydrogenase; Function of homologous gene experimentally demonstrated in an other organism; enzyme. (434 aa) |
| | crt | 3-hydroxybutyryl-CoA dehydratase (Crotonase); Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the enoyl-CoA hydratase/isomerase family. (254 aa) |
| | glyQS | Glycyl-tRNA synthetase (Glycine--tRNA ligase; Catalyzes the attachment of glycine to tRNA(Gly). Belongs to the class-II aminoacyl-tRNA synthetase family. (494 aa) |
| | hisA | 1-(5-phosphoribosyl)-5-[(5- phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase; Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase; Function of homologous gene experimentally demonstrated in an other organism; enzyme. (247 aa) |
| | hisH | Imidazole glycerol phosphate synthase subunit HisH; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF. (208 aa) |
| | hisB | Imidazoleglycerol-phosphate dehydratase (IGPD); Function of homologous gene experimentally demonstrated in an other organism; enzyme. (197 aa) |
| | ABZ96995.1 | Enoyl-CoA hydratase (Enoyl hydrase; Function of homologous gene experimentally demonstrated in an other organism; enzyme. (272 aa) |
| | ABZ96978.1 | Putative acetyl-CoA hydrolase/transferase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. (500 aa) |
| | aroE | Shikimate dehydrogenase; Function of homologous gene experimentally demonstrated in an other organism; enzyme. (296 aa) |
| | trpF | N-(5'-phosphoribosyl)anthranilate isomerase (PRAI); Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the TrpF family. (210 aa) |
| | serB | PSP; O-phosphoserine phosphohydrolase; PSPase; Function of homologous gene experimentally demonstrated in an other organism; enzyme. (305 aa) |
| | bioB | Biotin synthase (biotin synthetase); Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism; Belongs to the radical SAM superfamily. Biotin synthase family. (351 aa) |
| | bioA | 7,8-diamino-pelargonic acid aminotransferase; DAPA aminotransferase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (443 aa) |
| | bioD | Dethiobiotin synthetase; Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8- diaminopelargonic acid (DAPA) to form an ureido ring. (235 aa) |
| | carA | Carbamoyl-phosphate synthase, small chain (Carbamoyl-phosphate synthetase glutamine chain); Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the CarA family. (374 aa) |
| | ABZ96940.1 | Putative acyltransferase, MBOAT family; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme; Belongs to the membrane-bound acyltransferase family. (465 aa) |
| | ilvB1 | AHAS-I; Acetohydroxy-acid synthase I large subunit; ALS-I; Function of homologous gene experimentally demonstrated in an other organism; enzyme. (573 aa) |
| | ABZ96919.1 | Conserved hypothetical protein; Homologs of previously reported genes of unknown function. (263 aa) |
| | ABZ96917.1 | Putative metallo-beta-lactamase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. (340 aa) |
| | ABZ96916.1 | Putative acyl dehydratase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. (392 aa) |
| | pykF | Pyruvate kinase (PK); Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the pyruvate kinase family. (478 aa) |
| | ABZ96880.1 | Putative metallo-beta-lactamase superfamily protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. (308 aa) |
| | ABZ96878.1 | Conserved hypothetical protein; Homologs of previously reported genes of unknown function. (283 aa) |
| | dapB | Dihydrodipicolinate reductase (DHPR); Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate; Belongs to the DapB family. (267 aa) |
| | dapA | Dihydrodipicolinate synthase (DHDPS); Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA). (294 aa) |
| | hutH | Histidine ammonia-lyase (Histidase); Function of homologous gene experimentally demonstrated in an other organism; enzyme. (514 aa) |
| | ABZ96860.1 | Putative hydrolase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. (268 aa) |
| | bioF | 8-amino-7-oxononanoate synthase; Function of homologous gene experimentally demonstrated in an other organism; enzyme. (389 aa) |
| | dfpB | Phosphopantothenate--cysteine ligase; Phosphopantothenoylcysteine synthase; PPC synthetase; PPCS; CoaB; Function of homologous gene experimentally demonstrated in an other organism; enzyme. (225 aa) |
| | dfpA | Phosphopantothenoylcysteine decarboxylase (PPCDC; Function of homologous gene experimentally demonstrated in an other organism; enzyme. (176 aa) |
| | ilvC | Ketol-acid reductoisomerase; Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate. (333 aa) |
| | ABZ96839.1 | Putative acetyl-CoA acetyltransferase (Acetoacetyl-CoA thiolase); Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme; Belongs to the thiolase-like superfamily. Thiolase family. (439 aa) |
| | ABZ96829.1 | Hypothetical protein; No homology to any previously reported sequences. (352 aa) |
| | ABZ96825.1 | Lysine decarboxylase; Function of homologous gene experimentally demonstrated in an other organism; enzyme. (755 aa) |
| | gltX | Glutamyl-tRNA synthetase (Glutamate--tRNA ligase; Catalyzes the attachment of glutamate to tRNA(Glu) in a two- step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu). (517 aa) |
| | ABZ96767.1 | Hypothetical protein; No homology to any previously reported sequences. (288 aa) |
| | ilvI | AHAS; Acetohydroxy-acid synthase large subunit; ALS; Function of homologous gene experimentally demonstrated in an other organism; enzyme. (587 aa) |
| | fadB2 | 3-hydroxyacyl-CoA dehydrogenase, NAD binding FadB; Function of homologous gene experimentally demonstrated in an other organism; enzyme. (436 aa) |
| | fadA2 | 3-ketoacyl-CoA thiolase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the thiolase-like superfamily. Thiolase family. (421 aa) |
| | dapF | Diaminopimelate epimerase (DAP epimerase); Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L- lysine and an essential component of the bacterial peptidoglycan. (286 aa) |
| | ABZ96716.1 | Putative FAD dehydrogenase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. (470 aa) |
| | ABZ96696.1 | Putative biotin binding protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative factor. (169 aa) |
| | fabG6 | Biotin carboxylase (A subunit of acetyl-CoA carboxylase; Function of homologous gene experimentally demonstrated in an other organism; putative enzyme. (480 aa) |
| | ABZ96679.1 | Putative alginate o-acetyltransferase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme; Belongs to the membrane-bound acyltransferase family. (492 aa) |
| | ABZ96676.1 | Putative FAD-linked oxidase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. (481 aa) |
| | ABZ96658.1 | Acetyl-coenzyme A carboxyltransferase; Function of homologous gene experimentally demonstrated in an other organism; enzyme. (533 aa) |
| | glmS | Glucosamine--fructose-6-phosphate aminotransferase; Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source. (611 aa) |
| | ABZ96649.1 | Putative thiolase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. (509 aa) |
| | pheS | Phenylalanyl-tRNA synthetase alpha chain (Phenylalanine--tRNA ligase alpha chain; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily. (341 aa) |
| | gpmI | 2,3-bisphosphoglycerate-independent phosphoglycerate mutase; Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate; Belongs to the BPG-independent phosphoglycerate mutase family. (550 aa) |
| | ABZ96549.1 | Conserved hypothetical protein; Homologs of previously reported genes of unknown function. (187 aa) |
| | ABZ96522.1 | ABC-type transport system, permease, putative copper ABC transporter; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative transporter. (422 aa) |
| | ABZ96515.1 | Hypothetical protein; No homology to any previously reported sequences. (242 aa) |
| | thiL1 | Putative acetyl-CoA acetyltransferase (Acetoacetyl-CoA thiolase); Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the thiolase-like superfamily. Thiolase family. (393 aa) |
| | ABZ96484.1 | Conserved hypothetical protein; Homologs of previously reported genes of unknown function. (324 aa) |
| | ABZ96481.1 | Enoyl-CoA hydratase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the enoyl-CoA hydratase/isomerase family. (245 aa) |
| | fadD3 | Long-chain-fatty-acid--CoA ligase; Function of homologous gene experimentally demonstrated in an other organism; enzyme. (682 aa) |
| | ispF | 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase; Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2- C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP). (162 aa) |
| | nadA | Quinolinate synthetase A protein; Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate. (328 aa) |
| | algI | Putative poly(beta-D-mannuronate) O-acetylase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the membrane-bound acyltransferase family. (518 aa) |
| | pheT | Phenylalanyl-tRNA synthetase beta chain (Phenylalanine--tRNA ligase beta chain; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily. (799 aa) |
| | ABZ96444.1 | Acetyl-CoA hydrolase; Function of homologous gene experimentally demonstrated in an other organism; enzyme. (169 aa) |
| | aroH | Phospho-2-dehydro-3-deoxyheptonate aldolase, Trp-sensitive; Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D-arabino- heptulosonate-7-phosphate (DAHP). (349 aa) |
| | panB | 3-methyl-2-oxobutanoate hydroxymethyltransferase; Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha- ketoisovalerate to form ketopantoate; Belongs to the PanB family. (268 aa) |
| | folK | 2-amino-4-hydroxy-6- hydroxymethyldihydropteridine pyrophosphokinase; Function of homologous gene experimentally demonstrated in an other organism; enzyme. (157 aa) |
| | leuS | Leucyl-tRNA synthetase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the class-I aminoacyl-tRNA synthetase family. (867 aa) |
| | thrC | Threonine synthase; Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine. (449 aa) |
| | valS | Valyl-tRNA synthetase (Valine--tRNA ligase; Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA- dependent manner; Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily. (896 aa) |
| | fabI | Fatty acid synthase subunit beta; Function of homologous gene experimentally demonstrated in an other organism; enzyme. (390 aa) |
| | ispE | 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase; Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol. (306 aa) |
| | ABZ96337.1 | NADPH:quinone reductase; Function of homologous gene experimentally demonstrated in an other organism; enzyme. (332 aa) |
| | lysC | Aspartokinase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the aspartokinase family. (404 aa) |
| | ABZ96322.1 | Putative alginate O-acetyltransferase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; enzyme; Belongs to the membrane-bound acyltransferase family. (460 aa) |
| | purF | Amidophosphoribosyltransferase (Glutamine phosphoribosylpyrophosphate amidotransferase); Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine. (475 aa) |
| | maeB | NADP-dependent malic enzyme; Function of homologous gene experimentally demonstrated in an other organism; enzyme. (433 aa) |
| | ABZ96267.1 | Conserved hypothetical protein; Homologs of previously reported genes of unknown function. (187 aa) |
| | ABZ96255.1 | Putative enoyl-CoA hydratase/carnithine racemase; Function of homologous gene experimentally demonstrated in an other organism; enzyme. (261 aa) |
| | ABZ96254.1 | Long-chain-fatty-acid--CoA ligase; Function of homologous gene experimentally demonstrated in an other organism; enzyme. (641 aa) |
| | ABZ96236.1 | Conserved hypothetical protein; Homologs of previously reported genes of unknown function. (166 aa) |
| | argG | Argininosuccinate synthase (Citrulline--aspartate ligase); Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the argininosuccinate synthase family. Type 1 subfamily. (402 aa) |
| | pgi | GPI; Phosphoglucose isomerase; PGI; Phosphohexose isomerase; PHI; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the GPI family. (450 aa) |
| | ABZ96218.1 | Putative S-methyl-5-thioadenosine phosphorylase; Purine nucleoside phosphorylase involved in purine salvage. (287 aa) |
| | hom | Homoserine dehydrogenase (HDH); Function of homologous gene experimentally demonstrated in an other organism; enzyme. (427 aa) |
| | ABZ96199.1 | Putative enoyl-CoA hydratase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme; Belongs to the enoyl-CoA hydratase/isomerase family. (260 aa) |
| | ABZ96189.1 | Putative acetyltransferase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. (161 aa) |
| | cysE | Serine acetyltransferase; Function of homologous gene experimentally demonstrated in an other organism; enzyme. (238 aa) |
| | algI-2 | Alginate O-acetyltransferase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the membrane-bound acyltransferase family. (492 aa) |
| | asd | Aspartate semialdehyde dehydrogenase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the aspartate-semialdehyde dehydrogenase family. (349 aa) |
| | pykF-2 | Pyruvate kinase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the pyruvate kinase family. (477 aa) |
| | ABZ99790.1 | Putative alginate O-acetyltransferase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the membrane-bound acyltransferase family. (498 aa) |
| | ABZ99767.1 | Putative lysyl-tRNA synthetase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme; Belongs to the class-II aminoacyl-tRNA synthetase family. (323 aa) |
| | ABZ99745.1 | Alcohol dehydrogenase (Zinc-containing alcohol dehydrogenase family); Function of homologous gene experimentally demonstrated in an other organism; enzyme. (345 aa) |
| | kamA-2 | L-lysine 2,3-aminomutase; Function of homologous gene experimentally demonstrated in an other organism; enzyme. (354 aa) |
| | mtnB | Putative class II aldolase/adducin domain protein; Catalyzes the dehydration of methylthioribulose-1-phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P). Belongs to the aldolase class II family. MtnB subfamily. (209 aa) |
| | metH | Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. (1250 aa) |
| | pfkA | Diphosphate--fructose-6-phosphate 1-phosphotransferase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis; Belongs to the phosphofructokinase type A (PFKA) family. PPi-dependent PFK group II subfamily. Atypical ATP-dependent clade 'X' sub-subfamily. (435 aa) |
| | argB | Acetylglutamate kinase; Catalyzes the ATP-dependent phosphorylation of N-acetyl-L- glutamate; Belongs to the acetylglutamate kinase family. ArgB subfamily. (296 aa) |
| | alr | Alanine racemase; Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids; Belongs to the alanine racemase family. (376 aa) |
| | csdB | Cysteine desulfurase; Function of homologous gene experimentally demonstrated in an other organism; enzyme. (400 aa) |
| | aroK | Shikimate kinase; Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate; Belongs to the shikimate kinase family. (181 aa) |
| | gltB | Glutamate synthase large chain precursor; Function of homologous gene experimentally demonstrated in an other organism; enzyme. (1525 aa) |
| | gltD | Glutamate synthase (NADPH); Function of homologous gene experimentally demonstrated in an other organism; enzyme. (480 aa) |
| | aspA | Aspartate ammonia-lyase (aspartase); Function of homologous gene experimentally demonstrated in an other organism; enzyme. (468 aa) |
| | eapA | Putative alkyldihydroxyacetonephosphate synthase; Function of homologous gene experimentally demonstrated in an other organism; putative enzyme. (543 aa) |
| | ABZ99541.1 | Conserved hypothetical protein; Homologs of previously reported genes of unknown function. (307 aa) |
| | ilvE | Branched-chain-amino-acid aminotransferase; Acts on leucine, isoleucine and valine. Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family. (307 aa) |
| | serS | Seryl-tRNA synthetase; Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L- seryl-tRNA(Sec), which will be further converted into selenocysteinyl- tRNA(Sec). (418 aa) |
| | acsA | Acetyl-coenzyme A synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family. (654 aa) |
| | ABZ99497.1 | Putative ferredoxin--NADP reductase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; enzyme. (307 aa) |
| | ABZ99486.1 | Conserved hypothetical protein; Homologs of previously reported genes of unknown function. (337 aa) |
| | aroD | 3-dehydroquinate dehydratase; Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis- dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3-dehydroshikimate. Belongs to the type-I 3-dehydroquinase family. (238 aa) |
| | aroC | Chorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system. (378 aa) |
| | fadA1 | Thiolase I, 3-ketoacyl-CoA thiolase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the thiolase-like superfamily. Thiolase family. (404 aa) |
| | dapE | Succinyl-diaminopimelate desuccinylase (SDAP); Function of homologous gene experimentally demonstrated in an other organism; enzyme. (480 aa) |
| | ilvD | Dihydroxy-acid dehydratase (DAD); Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the IlvD/Edd family. (558 aa) |
| | ABZ99388.1 | Putative arylesterase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. (346 aa) |
| | metG | Methionyl-tRNA synthetase (Methionine--tRNA ligase); Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation. (681 aa) |
| | ABZ99370.1 | Putative phosphoribosyl-AMP cyclohydrolase; Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP; Belongs to the PRA-CH family. (202 aa) |
| | metF | 5,10-methylenetetrahydrofolate reductase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the methylenetetrahydrofolate reductase family. (295 aa) |
| | fadB3 | 3-hydroxyacyl-CoA dehydrogenase, NAD binding FadB; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the enoyl-CoA hydratase/isomerase family. (257 aa) |
| | sulI | Dihydropteroate synthase type I (DHPS; Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8- dihydropteroate (H2Pte), the immediate precursor of folate derivatives. (271 aa) |
| | hisS | Histidyl-tRNA synthetase (Histidine--tRNA ligase; Function of homologous gene experimentally demonstrated in an other organism; enzyme. (437 aa) |
| | argJ | Arginine biosynthesis bifunctional protein ArgJ alpha chain; Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis: the synthesis of N-acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate. Belongs to the ArgJ family. (384 aa) |
| | ABZ99270.1 | Putative sulfurtransferase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; enzyme. (283 aa) |
| | gcvP | Glycine dehydrogenase [decarboxylating] (Glycine cleavage system P protein); The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. (973 aa) |
| | gcvH | Glycine cleavage system H protein; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein. (130 aa) |
| | gcvT | Aminomethyltransferase (Glycine cleavage system T protein); The glycine cleavage system catalyzes the degradation of glycine. (370 aa) |
| | ABZ99252.1 | Putative Zinc-dependent dehydrogenase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. (339 aa) |
| | ABZ99242.1 | Putative Zn-dependent hydrolase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. (362 aa) |
| | ABZ99231.1 | Putative MaoC-like dehydratase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. (139 aa) |
| | fumC | Fumarate hydratase class II (Fumarase C); Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily. (462 aa) |
| | ABZ99183.1 | Putative alcohol dehydrogenase, zinc-containing alcohol dehydrogenase family; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; enzyme. (415 aa) |
| | ABZ99181.1 | Putative NADPH:quinone reductase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; enzyme. (337 aa) |
| | ABZ99162.1 | Putative membrane bound 0-acyl transferase, putative alginate biosynthesis protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme; Belongs to the membrane-bound acyltransferase family. (456 aa) |
| | acsA1 | Acetoacetyl-coenzyme A synthetase (Acetoacetate--CoA ligase 1; Function of homologous gene experimentally demonstrated in an other organism; enzyme. (652 aa) |
| | cysK2 | Cysteine synthase A; O-acetylserine sulfhydrylase; O-acetylserine (Thiol)-lyase; CSase); Function of homologous gene experimentally demonstrated in an other organism; enzyme. (324 aa) |
| | ABZ99119.1 | Putative L-threonine 3-dehydrogenase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. (340 aa) |
| | ABZ99046.1 | Conserved hypothetical protein; Belongs to the glutamate synthase family. (526 aa) |
| | algI3 | Alginate O-acetyltransferase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the membrane-bound acyltransferase family. (488 aa) |
| | mtnC | Putative enolase-phosphatase E-1; Bifunctional enzyme that catalyzes the enolization of 2,3- diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK- MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene). Belongs to the HAD-like hydrolase superfamily. MasA/MtnC family. (247 aa) |
| | fadD1 | Long-chain acyl-CoA synthetase (AMP-forming); Function of homologous gene experimentally demonstrated in an other organism; enzyme. (629 aa) |
| | mtnA | Putative 5-methylthioribose-1-phosphate isomerase (MTNA); Catalyzes the interconversion of methylthioribose-1-phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P). (357 aa) |
| | ABZ98964.1 | Putative metallo-beta-lactamase superfamily protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. (315 aa) |
| | icd | Isocitrate dehydrogenase (NADP); Oxalosuccinate decarboxylase; IDH; NADP(+)-specific ICDH; IDP; CtIDP1); Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the isocitrate and isopropylmalate dehydrogenases family. (403 aa) |
| | ABZ98929.1 | Putative glutamine amidotransferase, class-I; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. (229 aa) |
| | ABZ98905.1 | Hypothetical protein; No homology to any previously reported sequences. (160 aa) |
| | gabT | 4-aminobutyrate aminotransferase; Includes: ((S)-3-amino-2-methylpropionate transaminase); (Gamma-amino-N-butyrate transaminase; GABA transaminase; Glutamate:succinic semialdehyde; transaminase; GABA aminotransferase; GABA-AT; L-AIBAT); Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (429 aa) |
| | ABZ98727.1 | Hypothetical protein; No homology to any previously reported sequences. (422 aa) |
| | acpS | Holo-[acyl-carrier-protein] synthase (Holo-ACP synthase; Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein; Belongs to the P-Pant transferase superfamily. AcpS family. (127 aa) |
| | ABZ98716.1 | Putative strictosidine synthase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. (346 aa) |
| | ABZ98709.1 | Putative hydroxyacylglutathione hydrolase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. (238 aa) |
| | dxr | 1-deoxy-D-xylulose 5-phosphate reductoisomerase 2; Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4- phosphate (MEP); Belongs to the DXR family. (386 aa) |
| | proS | Prolyl-tRNA synthetase (Proline--tRNA ligase; Catalyzes the attachment of proline to tRNA(Pro) in a two- step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' ed [...] (586 aa) |
| | trpB | Tryptophan synthase beta chain; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine. (396 aa) |
| | trpA | Tryptophan synthase alpha protein; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family. (266 aa) |
| | dxs | 1-deoxy-D-xylulose-5-phosphate synthase; Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D- xylulose-5-phosphate (DXP); Belongs to the transketolase family. DXPS subfamily. (629 aa) |
| | aroA | 3-phosphoshikimate 1-carboxyvinyltransferase; Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate. (428 aa) |
| | hisG | ATP phosphoribosyltransferase; Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity. Belongs to the ATP phosphoribosyltransferase family. Short subfamily. (204 aa) |
| | plsX | Fatty acid/phospholipid synthesis protein PlsX; Catalyzes the reversible formation of acyl-phosphate (acyl- PO(4)) from acyl-[acyl-carrier-protein] (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA. (340 aa) |
| | ABZ98667.1 | Hypothetical protein; No homology to any previously reported sequences. (497 aa) |
| | acpP | Acyl carrier protein (ACP); Carrier of the growing fatty acid chain in fatty acid biosynthesis; Belongs to the acyl carrier protein (ACP) family. (77 aa) |
| | aroB2 | 3-dehydroquinate synthase; Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ). (366 aa) |
| | metZ | Putative Cys/Met metabolism PLP-dependent enzyme; Catalyzes the formation of L-homocysteine from O-succinyl-L- homoserine (OSHS) and hydrogen sulfide. (394 aa) |
| | ABZ98646.1 | Putative thiosulfate sulfurtransferase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. (298 aa) |
| | ppc-2 | Phosphoenolpyruvate carboxylase (PEPCase; Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle. (71 aa) |
| | ppc | Phosphoenolpyruvate carboxylase; Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle. (671 aa) |
| | eutB | Ethanolamine ammonia-lyase, heavy chain (Ethanolamine ammonia-lyase large subunit); Function of homologous gene experimentally demonstrated in an other organism; enzyme. (461 aa) |
| | eutC | Ethanolamine ammonia-lyase, light chain (Ethanolamine ammonia-lyase small subunit); Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the EutC family. (262 aa) |
| | ABZ98564.1 | Putative alcohol dehydrogenase, zinc-containing; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. (334 aa) |
| | aroB1 | 3-dehydroquinate synthase; Function of homologous gene experimentally demonstrated in an other organism; enzyme. (387 aa) |
| | panE | 2-dehydropantoate 2-reductase; Function of homologous gene experimentally demonstrated in an other organism; enzyme. (324 aa) |
| | dkgA | 2,5-DKG reductase A; 2,5-DKGR A; 25DKGR-A; AKR5C; Function of homologous gene experimentally demonstrated in an other organism; enzyme. (275 aa) |
| | argF | Ornithine carbamoyltransferase (OTCase); Function of homologous gene experimentally demonstrated in an other organism; enzyme. (310 aa) |
| | hycD | Hydrogenase-4 subunit D; Function of homologous gene experimentally demonstrated in an other organism; enzyme. (292 aa) |
| | hyfE | Hydrogenase-4 subunit E; Function of homologous gene experimentally demonstrated in an other organism; enzyme. (203 aa) |
| | thrS | Threonyl-tRNA synthetase (Threonine--tRNA ligase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the class-II aminoacyl-tRNA synthetase family. (638 aa) |
| | tyrA | Prephenate dehydrogenase; Function of homologous gene experimentally demonstrated in an other organism; enzyme. (297 aa) |
| | ABZ98465.1 | Conserved hypothetical protein; Homologs of previously reported genes of unknown function. (324 aa) |
| | serC | Phosphoserine aminotransferase (PSAT); Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine; Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily. (365 aa) |
| | ilvB2 | AHAS; Acetohydroxy-acid synthase large subunit; ALS); Function of homologous gene experimentally demonstrated in an other organism; enzyme. (575 aa) |
| | ilvH | AHAS; Acetohydroxy-acid synthase small subunit; ALS); Function of homologous gene experimentally demonstrated in an other organism; enzyme. (162 aa) |
| | ABZ98442.1 | Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex); Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; enzyme. (82 aa) |
| | leuB | 3-isopropylmalate dehydrogenase; Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate. (359 aa) |
| | argD | Acetylornithine aminotransferase (ACOAT); Function of homologous gene experimentally demonstrated in an other organism; enzyme. (405 aa) |
| | panD | Aspartate 1-decarboxylase (precursor) (Aspartate alpha-decarboxylase); Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine. (118 aa) |
| | ileS | Isoleucyl-tRNA synthetase (Isoleucine--tRNA ligase; Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile). Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 1 subfamily. (915 aa) |
| | aspS | Aspartyl-tRNA synthetase (Aspartate--tRNA ligase; Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction: L-aspartate is first activated by ATP to form Asp- AMP and then transferred to the acceptor end of tRNA(Asp). Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily. (601 aa) |
| | argS | Arginyl-tRNA synthetase (Arginine--tRNA ligase; Function of homologous gene experimentally demonstrated in an other organism; enzyme. (594 aa) |
| | tpiA | Triosephosphate isomerase (TIM; Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P); Belongs to the triosephosphate isomerase family. (249 aa) |
| | pgk | Phosphoglycerate kinase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the phosphoglycerate kinase family. (396 aa) |
| | gap | Glyceraldehyde-3-phosphate dehydrogenase (GAPDH; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family. (335 aa) |
| | ABZ98122.1 | Hypothetical protein; No homology to any previously reported sequences. (358 aa) |
| | ABZ98110.1 | Putative poly(beta-D-mannuronate) O-acetylase (Alginate biosynthesis protein AlgI); Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. (291 aa) |
| | ABZ98038.1 | Putative histidyl-tRNA synthetase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. (348 aa) |
| | mvaB | HMG-CoA lyase; HL; 3-hydroxy-3-methylglutarate-CoA lyase); Function of homologous gene experimentally demonstrated in an other organism; enzyme. (299 aa) |
| | purQ | Phosphoribosylformylglycinamidine synthase I (FGAM synthase I); Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is t [...] (215 aa) |
| | sufS | Cysteine desulfurase; Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L-selenocystine to produce L-alanine. (414 aa) |
| | ABZ98003.1 | Putative hydroxyacylglutathione hydrolase; Thiolesterase that catalyzes the hydrolysis of S-D-lactoyl- glutathione to form glutathione and D-lactic acid. Belongs to the metallo-beta-lactamase superfamily. Glyoxalase II family. (258 aa) |
| | lysS | Lysyl-tRNA synthetase (Lysine--tRNA ligase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the class-II aminoacyl-tRNA synthetase family. (497 aa) |
| | ABZ97983.1 | Long-chain acyl-CoA synthetase, AMP-forming; Function of homologous gene experimentally demonstrated in an other organism; enzyme. (624 aa) |
| | hisC | Histidinol-phosphate aminotransferase (Imidazole acetol-phosphate transaminase); Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily. (364 aa) |
| | leuA | 2-isopropylmalate synthase (Alpha-isopropylmalate synthase; Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3- hydroxy-4-methylpentanoate (2-isopropylmalate); Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily. (500 aa) |
| | hisD | Histidinol dehydrogenase; Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine. (430 aa) |
| | panC | Pantoate--beta-alanine ligase (Pantothenate synthetase; Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate. Belongs to the pantothenate synthetase family. (283 aa) |
| | ABZ97924.1 | Putative poly(beta-D-mannuronate) O-acetylase (Alginate biosynthesis protein AlgI); Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; enzyme; Belongs to the membrane-bound acyltransferase family. (474 aa) |
| | kamA | L-lysine 2,3-aminomutase; Function of homologous gene experimentally demonstrated in an other organism; enzyme. (402 aa) |
| | ABZ97901.1 | Conserved hypothetical protein; Homologs of previously reported genes of unknown function. (231 aa) |
| | ABZ97899.1 | Putative acetylglutamate kinase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. (385 aa) |
| | ABZ97896.1 | Putative acetyl-CoA C-acyltransferase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme; Belongs to the thiolase-like superfamily. Thiolase family. (366 aa) |
| | ABZ97892.1 | Putative enoyl-CoA hydratase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. (252 aa) |
| | ABZ97891.1 | Putative N-acyl-L-amino acid amidohydrolase, M20D peptidase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; enzyme. (392 aa) |
| | proA | Gamma-glutamyl phosphate reductase; Catalyzes the NADPH-dependent reduction of L-glutamate 5- phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate. Belongs to the gamma-glutamyl phosphate reductase family. (421 aa) |
| | proB | Glutamate 5-kinase (Gamma-glutamyl kinase; Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate. (287 aa) |
| | gatC | Glutamyl-tRNA(Gln) amidotransferase subunit C 1 (Glu-ADT subunit C 1); Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl- tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp- tRNA(Asn) or phospho-Glu-tRNA(Gln); Belongs to the GatC family. (94 aa) |
| | hisF | Imidazole glycerol phosphate synthase subunit HisF; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit. (255 aa) |
| | cysS | Cysteinyl-tRNA synthetase (Cysteine--tRNA ligase); Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the class-I aminoacyl-tRNA synthetase family. (485 aa) |
| | folD | Methenyltetrahydrofolate cyclohydrolase; Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate. (291 aa) |
| | asnS | Asparaginyl-tRNA synthetase (Asparagine--tRNA ligase; Function of homologous gene experimentally demonstrated in an other organism; enzyme. (434 aa) |
| | eno | Enolase (2-phosphoglycerate dehydratase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family. (433 aa) |
| | ABZ97808.1 | Hypothetical protein; No homology to any previously reported sequences. (356 aa) |
| | kdsA | Phospho-2-dehydro-3-deoxyoctonate aldolase; 3-deoxy-D-manno-octulosonic acid 8-phosphate synthetase; KDO-8-phosphate synthetase; KDO 8-P synthase; (KDOPS; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the KdsA family. (281 aa) |
| | pyrG | CTP synthase (UTP--ammonia ligase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates. (540 aa) |
| | ABZ97747.1 | Putative long-chain-fatty-acid CoA ligase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. (644 aa) |
| | cysM | Cysteine synthase B; O-acetylserine sulfhydrylase B; O-acetylserine (Thiol)-lyase B; CSase B); Function of homologous gene experimentally demonstrated in an other organism; enzyme. (333 aa) |
| | leuD2 | 3-isopropylmalate dehydratase small subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. Belongs to the LeuD family. LeuD type 1 subfamily. (208 aa) |
| | leuC2 | 3-isopropylmalate dehydratase large subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. (464 aa) |
| | guaA | GMP synthetase [glutamine-hydrolyzing] (Glutamine amidotransferase; Function of homologous gene experimentally demonstrated in an other organism; enzyme. (599 aa) |
| | argH | Argininosuccinate lyase (Arginosuccinase; Function of homologous gene experimentally demonstrated in an other organism; enzyme. (478 aa) |
| | metY | O-acetylhomoserine sulfhydrylase; Function of homologous gene experimentally demonstrated in an other organism; enzyme. (434 aa) |
| | metX | Homoserine O-acetyltransferase; Transfers an acetyl group from acetyl-CoA to L-homoserine, forming acetyl-L-homoserine. (378 aa) |
| | ilvA | Threonine dehydratase biosynthetic; Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2- ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA. (425 aa) |
| | ispH | 4-hydroxy-3-methylbut-2-enyl diphosphate reductase; Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis. Belongs to the IspH family. (315 aa) |
| | fabG7 | Biotin carboxylase (A subunit of acetyl-CoA carboxylase; Function of homologous gene experimentally demonstrated in an other organism; enzyme. (917 aa) |
| | accA | Acetyl-CoA carboxylase alpha subunit; Function of homologous gene experimentally demonstrated in an other organism; enzyme. (548 aa) |
| | tyrS | Tyrosyl-tRNA synthetase (Tyrosine--tRNA ligase; Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two- step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr); Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 2 subfamily. (408 aa) |
| | acoA | Pyruvate dehydrogenase E1 alpha subunit; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). (322 aa) |
| | acoB | Pyruvate dehydrogenase E1 beta subunit; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2. (324 aa) |
| | acoC | Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). (464 aa) |
| | ABZ97658.1 | Putative L-fuculose-phosphate aldolase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. (218 aa) |
| | ABZ97651.1 | Putative zinc-containing alcohol dehydrogenase superfamily; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; enzyme. (333 aa) |
| | ABZ97647.1 | Conserved hypothetical protein; Homologs of previously reported genes of unknown function. (400 aa) |
| | argC | N-acetyl-gamma-glutamyl-phosphate reductase; Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde. Belongs to the NAGSA dehydrogenase family. Type 1 subfamily. (346 aa) |
| | ABZ97589.1 | Conserved hypothetical protein; Homologs of previously reported genes of unknown function. (196 aa) |
| | lipA | Lipoyl synthase; Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives. (306 aa) |
| | ABZ97566.1 | Conserved hypothetical protein; Homologs of previously reported genes of unknown function. (440 aa) |
| | ispD | 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase; 4-diphosphocytidyl-2C-methyl-D-erythritol synthase; MEP cytidylyltransferase; MCT; Function of homologous gene experimentally demonstrated in an other organism; enzyme. (229 aa) |
| | lysA | Diaminopimelate decarboxylase (DAP decarboxylase); Function of homologous gene experimentally demonstrated in an other organism; enzyme. (422 aa) |
| | fbaB | Fructose-bisphosphate aldolase class I (FBP aldolase); Function of homologous gene experimentally demonstrated in an other organism; enzyme. (354 aa) |
| | glnA | Glutamine synthetase (Glutamate--ammonia ligase); Function of homologous gene experimentally demonstrated in an other organism; enzyme. (486 aa) |
| | trpD | Anthranilate phosphoribosyltransferase; Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'- phosphoribosyl)-anthranilate (PRA). (330 aa) |
| | alaS | Alanyl-tRNA synthetase (Alanine--tRNA ligase; Catalyzes the attachment of alanine to tRNA(Ala) in a two- step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain. (919 aa) |
| | fadB1 | Enoyl-CoA hydratase; Function of homologous gene experimentally demonstrated in an other organism; enzyme. (277 aa) |
| | proC | Pyrroline-5-carboxylate reductase (P5CR; Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline. (247 aa) |
| | ABZ97432.1 | Putative metal-dependent hydrolase of the beta-lactamase superfamily I; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. (318 aa) |
| | mtnD | Putative acireductone dioxygenase, ARD; Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway. (179 aa) |
| | leuA1 | 2-isopropylmalate synthase (Alpha-isopropylmalate synthase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the alpha-IPM synthase/homocitrate synthase family. (511 aa) |
| | ispG | 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase (flavodoxin); Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME- 2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate. Belongs to the IspG family. (675 aa) |
| | carB | Carbamoyl-phosphate synthase large chain (Carbamoyl-phosphate synthetase ammonia chain); Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the CarB family. (1103 aa) |
| | ABZ97374.1 | Hypothetical protein; No homology to any previously reported sequences. (368 aa) |
| | ABZ97353.1 | Putative dihydrofolate reductase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. (184 aa) |
| | leuD1 | 3-isopropylmalate dehydratase small subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. Belongs to the LeuD family. LeuD type 1 subfamily. (208 aa) |
| | leuC1 | 3-isopropylmalate dehydratase large subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. (467 aa) |
| | ABZ97328.1 | Putative dihydrofolate reductase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. (187 aa) |
| | trpC | Indole-3-glycerol phosphate synthase (IGPS); Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the TrpC family. (258 aa) |
| | ABZ97311.1 | Putative enoyl-(Acyl-carrier-protein) reductase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. (278 aa) |
| | cysI | Sulfite reductase [NADPH] hemoprotein beta-component (SIR-HP; Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L-cysteine from sulfate. Belongs to the nitrite and sulfite reductase 4Fe-4S domain family. (555 aa) |
| | cysJ | Sulfite reductase [NADPH] flavoprotein alpha-component (SIR-FP); Function of homologous gene experimentally demonstrated in an other organism; enzyme. (587 aa) |
| | cysK1 | Cysteine synthase A; O-acetylserine sulfhydrylase; O-acetylserine (Thiol)-lyase; CSase); Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the cysteine synthase/cystathionine beta- synthase family. (304 aa) |
| | mdh | Malate dehydrogenase; Catalyzes the reversible oxidation of malate to oxaloacetate. Belongs to the LDH/MDH superfamily. MDH type 2 family. (327 aa) |
| | thrB | Homoserine kinase (HSK; Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate; Belongs to the GHMP kinase family. Homoserine kinase subfamily. (317 aa) |
| | trpS | Tryptophanyl-tRNA synthetase (Tryptophan--tRNA ligase; Catalyzes the attachment of tryptophan to tRNA(Trp). Belongs to the class-I aminoacyl-tRNA synthetase family. (322 aa) |
| | ABZ97242.1 | Putative haloacid dehalogenase-like hydrolase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. (275 aa) |
| | ABZ97237.1 | Putative amine oxidase (flavin-containing); Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. (458 aa) |
| | ABZ97233.1 | Putative MaoC family dehydratase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. (140 aa) |
| | fadD2 | Long-chain acyl-CoA synthetase, AMP-forming (Acyl-CoA synthetase); Function of homologous gene experimentally demonstrated in an other organism; enzyme. (639 aa) |
| | leuA2 | 2-isopropylmalate synthase (Alpha-isopropylmalate synthase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the alpha-IPM synthase/homocitrate synthase family. (394 aa) |
| | ABZ97214.1 | Putative Zn-dependent hydrolase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. (398 aa) |
| | ABZ97212.1 | Putative metallo-hydrolase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. (320 aa) |
| | sucB | Dihydrolipoyllysine-residue succinyltransferase component of 2-oxoglutarate dehydrogenase complex; E2 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the second step in the conversion of 2- oxoglutarate to succinyl-CoA and CO(2). (410 aa) |
| | sucA | 2-oxoglutarate dehydrogenase E1 component (Alpha-ketoglutarate dehydrogenase); Function of homologous gene experimentally demonstrated in an other organism; enzyme. (922 aa) |
| | dapL | Putative aspartate aminotransferase; Involved in the synthesis of meso-diaminopimelate (m-DAP or DL-DAP), required for both lysine and peptidoglycan biosynthesis. Catalyzes the direct conversion of tetrahydrodipicolinate to LL- diaminopimelate. (408 aa) |
| | ABZ97148.1 | Putative acyl-CoA thioester hydrolase (modular protein); Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. (126 aa) |
