Your Input: | |
| | gpsA2 | Glycerol-3-phosphate dehydrogenase [NAD(P)+] (NAD(P)H-dependent glycerol-3-phosphate dehydrogenase); Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family. (333 aa) |
| | ispF | 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase; Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2- C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP). (162 aa) |
| | nadA | Quinolinate synthetase A protein; Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate. (328 aa) |
| | pyrC | Dihydroorotase (Carbamoylaspartic dehydras; Function of homologous gene experimentally demonstrated in an other organism; enzyme. (414 aa) |
| | purD | Phosphoribosylamine--glycine ligase; GARS; Glycinamide ribonucleotide synthetase; Phosphoribosylglycinamide synthetase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the GARS family. (425 aa) |
| | ABZ96391.1 | Conserved hypothetical protein; Homologs of previously reported genes of unknown function. (283 aa) |
| | ispE | 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase; Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol. (306 aa) |
| | glmU | UDP-N-acetylglucosamine pyrophosphorylase; Function of homologous gene experimentally demonstrated in an other organism; enzyme. (253 aa) |
| | prs | Ribose-phosphate pyrophosphokinase (Phosphoribosyl pyrophosphate synthetase); Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib- 5-P); Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily. (313 aa) |
| | ABZ96372.1 | Glycerol-3-phosphate dehydrogenase (NAD(P)(+)); Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family. (806 aa) |
| | ABZ96330.1 | Conserved hypothetical protein; Homologs of previously reported genes of unknown function. (516 aa) |
| | purF | Amidophosphoribosyltransferase (Glutamine phosphoribosylpyrophosphate amidotransferase); Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine. (475 aa) |
| | ABZ96310.1 | Hypothetical protein; No homology to any previously reported sequences. (82 aa) |
| | pyrD | Dihydroorotate dehydrogenase (Dihydroorotate oxydase); Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor; Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily. (357 aa) |
| | coaD | Phosphopantetheine adenylyltransferase; Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Belongs to the bacterial CoaD family. (160 aa) |
| | ndk | Nucleoside diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family. (137 aa) |
| | purB | Adenylosuccinate lyase; Adenylosuccinase; ASL; Glutamyl-tRNA synthetase regulatory factor; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. (434 aa) |
| | ABZ97647.1 | Conserved hypothetical protein; Homologs of previously reported genes of unknown function. (400 aa) |
| | dut | Deoxyuridine 5'-triphosphate nucleotidohydrolase (dUTPase; This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA; Belongs to the dUTPase family. (149 aa) |
| | purN | Phosphoribosylglycinamide formyltransferase; Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate. (204 aa) |
| | purH | Bifunctional protein: phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase; Includes: phosphoribosylaminoimidazolecarboxamide formyltransferase (AICAR transformylase); IMP cyclohydrolase (Inosinicase; IMP synthetase) (ATIC); Function of homologous gene experimentally demonstrated in an other organism; enzyme. (513 aa) |
| | coaE | Dephospho-CoA kinase (Dephosphocoenzyme A kinase); Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; Belongs to the CoaE family. (205 aa) |
| | ispD | 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase; 4-diphosphocytidyl-2C-methyl-D-erythritol synthase; MEP cytidylyltransferase; MCT; Function of homologous gene experimentally demonstrated in an other organism; enzyme. (229 aa) |
| | purE | Phosphoribosylaminoimidazole carboxylase catalytic subunit (AIR carboxylase; Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR). (165 aa) |
| | folD | Methenyltetrahydrofolate cyclohydrolase; Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate. (291 aa) |
| | purK | Phosphoribosylaminoimidazole carboxylase ATPase subunit (AIR carboxylase; Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR). (366 aa) |
| | pyrG | CTP synthase (UTP--ammonia ligase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates. (540 aa) |
| | gmhA | Phosphoheptose isomerase (Sedoheptulose 7-phosphate isomerase); Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate; Belongs to the SIS family. GmhA subfamily. (195 aa) |
| | guaA | GMP synthetase [glutamine-hydrolyzing] (Glutamine amidotransferase; Function of homologous gene experimentally demonstrated in an other organism; enzyme. (599 aa) |
| | ispH | 4-hydroxy-3-methylbut-2-enyl diphosphate reductase; Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis. Belongs to the IspH family. (315 aa) |
| | pgsA | CDP-diacylglycerol---glycerol-3-phosphate 3-phosphatidyltransferase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the CDP-alcohol phosphatidyltransferase class-I family. (224 aa) |
| | plsY | Conserved hypothetical protein; Catalyzes the transfer of an acyl group from acyl-phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP. (206 aa) |
| | pdxH | Pyridoxamine 5'-phosphate oxidase; Catalyzes the oxidation of either pyridoxine 5'-phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP). (212 aa) |
| | ABZ97506.1 | CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase; Phosphatidylglycerophosphate synthase; PGP synthase; putative membrane protein; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the CDP-alcohol phosphatidyltransferase class-I family. (248 aa) |
| | thiL | Thiamine-monophosphate kinase (Thiamine-phosphate kinase); Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1; Belongs to the thiamine-monophosphate kinase family. (302 aa) |
| | ABZ97487.1 | Hypothetical protein; No homology to any previously reported sequences. (249 aa) |
| | nadE | Putative glutamine-dependent NAD(+) synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source. (646 aa) |
| | pssA | CDP-diacylglycerol--serine O-phosphatidyltransferase; Phosphatidylserine synthase; putative membrane protein; putative signal peptide; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the CDP-alcohol phosphatidyltransferase class-I family. (251 aa) |
| | ispG | 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase (flavodoxin); Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME- 2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate. Belongs to the IspG family. (675 aa) |
| | carB | Carbamoyl-phosphate synthase large chain (Carbamoyl-phosphate synthetase ammonia chain); Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the CarB family. (1103 aa) |
| | guaB | Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. (508 aa) |
| | tmk | Thymidylate kinase (dTMP kinase); Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis; Belongs to the thymidylate kinase family. (203 aa) |
| | ABZ97253.1 | Putative adenylate cyclase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. (450 aa) |
| | ABZ97201.1 | Putative adenylate cyclase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. (410 aa) |
| | ABZ97197.1 | Putative membrane-bound phosphoesterase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. (399 aa) |
| | pdxA | 4-hydroxythreonine-4-phosphate dehydrogenase (4-(phosphohydroxy)-L-threonine dehydrogenase); Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the PdxA family. (314 aa) |
| | pyrB | Aspartate carbamoyltransferase, catalytic subunit (Aspartate transcarbamylase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family. (310 aa) |
| | ABZ97121.1 | Putative adenylate cyclase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. (618 aa) |
| | ABZ97091.1 | Putative transcriptional activator, TenA family; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative regulator. (231 aa) |
| | fliI | Flagellum-specific ATP synthase; Function of homologous gene experimentally demonstrated in an other organism; enzyme. (454 aa) |
| | gmk | Guanylate kinase; Essential for recycling GMP and indirectly, cGMP. (187 aa) |
| | lpxK | Putative tetraacyldisaccharide 4'-kinase (Lipid A 4'-kinase); Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1-P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA). (374 aa) |
| | purM | Phosphoribosylaminoimidazole synthetase; Function of homologous gene experimentally demonstrated in an other organism; enzyme. (342 aa) |
| | carA | Carbamoyl-phosphate synthase, small chain (Carbamoyl-phosphate synthetase glutamine chain); Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the CarA family. (374 aa) |
| | atpC | ATP synthase F1, epsilon subunit; Produces ATP from ADP in the presence of a proton gradient across the membrane. (126 aa) |
| | atpD | ATP synthase F1, beta subunit; Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits; Belongs to the ATPase alpha/beta chains family. (468 aa) |
| | atpG | ATP synthase F1, gamma subunit; Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex. (289 aa) |
| | atpA | ATP synthase F1, alpha subunit; Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit. Belongs to the ATPase alpha/beta chains family. (504 aa) |
| | atpH | ATP synthase F1, delta subunit; F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation; Belongs to the ATPase delta chain family. (187 aa) |
| | atpF | ATP synthase F0, B subunit; F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. (174 aa) |
| | atpE | ATP synthase F0, C subunit (Lipid-binding protein); F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. (94 aa) |
| | atpB | ATP synthase F0, A subunit; Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane. (309 aa) |
| | ABZ96870.1 | Putative adenylate or guanylate cyclase, family 3; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative membrane component; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (853 aa) |
| | dacA | Conserved hypothetical protein; Catalyzes the condensation of 2 ATP molecules into cyclic di- AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria. (276 aa) |
| | ABZ96863.1 | Conserved hypothetical protein; Homologs of previously reported genes of unknown function; putative membrane component. (327 aa) |
| | apt | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. (201 aa) |
| | pyrF | Orotidine-5'-monophosphate decarboxylase; Function of homologous gene experimentally demonstrated in an other organism; enzyme. (272 aa) |
| | ABZ99578.1 | Hypothetical protein; Homologs of previously reported genes of unknown function. (309 aa) |
| | folE | GTP cyclohydrolase I; Function of homologous gene experimentally demonstrated in an other organism; enzyme. (183 aa) |
| | acsA | Acetyl-coenzyme A synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family. (654 aa) |
| | ABZ99440.1 | Conserved hypothetical protein; Homologs of previously reported genes of unknown function; Belongs to the UPF0301 (AlgH) family. (188 aa) |
| | ABZ99371.1 | Putative adenylate cyclase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. (432 aa) |
| | thyX | Thymidylate synthase ThyX (TS; Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NADPH and FADH(2) as the reductant. (307 aa) |
| | coaX | Conserved hypothetical protein; Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis. (263 aa) |
| | dcd | Deoxycytidine triphosphate deaminase (dCTP deaminase); Bifunctional enzyme that catalyzes both the deamination of dCTP to dUTP and the hydrolysis of dUTP to dUMP without releasing the toxic dUTP intermediate. (174 aa) |
| | ABZ99262.1 | Putative acyltransferase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. (291 aa) |
| | ABZ99227.1 | Hypothetical protein; No homology to any previously reported sequences. (422 aa) |
| | ABZ99224.1 | Hypothetical protein; No homology to any previously reported sequences. (46 aa) |
| | ABZ99223.1 | Hypothetical protein; No homology to any previously reported sequences. (89 aa) |
| | hpt | Hypoxanthine phosphoribosyltransferase (HPRT); Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the purine/pyrimidine phosphoribosyltransferase family. (170 aa) |
| | acsA1 | Acetoacetyl-coenzyme A synthetase (Acetoacetate--CoA ligase 1; Function of homologous gene experimentally demonstrated in an other organism; enzyme. (652 aa) |
| | ribF | Riboflavin biosynthesis protein RibF; Includes: Riboflavin kinase (Flavokinase); FMN adenylyltransferase (FAD pyrophosphorylase; FAD synthetase); Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the ribF family. (309 aa) |
| | ABZ99112.1 | Putative adenylate/guanylate cyclase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. (311 aa) |
| | ABZ99103.1 | Putative acyltransferase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. (257 aa) |
| | ABZ99047.1 | Putative adenylate cyclase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. (691 aa) |
| | ABZ99013.1 | Putative adenylate cyclase, family 3 or guanylate cyclase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. (619 aa) |
| | ABZ99012.1 | Putative adenylate/guanylate cyclase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. (706 aa) |
| | ABZ98959.1 | Putative adenylate cyclase, family 3; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. (430 aa) |
| | ABZ98929.1 | Putative glutamine amidotransferase, class-I; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. (229 aa) |
| | ABZ98854.1 | Putative molybdopterin-guanine dinucleotide biosynthesis protein MobA; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. (194 aa) |
| | moaE | MPT synthase subunit 2; Molybdopterin synthase subunit 2; Molybdenum cofactor biosynthesis protein E; Molybdopterin-converting factor large subunit); Function of homologous gene experimentally demonstrated in an other organism; factor. (141 aa) |
| | moaD | Molybdopterin cofactor biosynthesis protein D; Function of homologous gene experimentally demonstrated in an other organism; enzyme. (80 aa) |
| | moaA | Molybdenum cofactor biosynthesis protein A; Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate. (313 aa) |
| | moeA | Molybdopterin biosynthesis protein MoeA; Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP. Belongs to the MoeA family. (396 aa) |
| | moaCB | Cyclic pyranopterin monophosphate synthase; Includes: molybdenum cofactor biosynthesis protein C; molybdenum cofactor biosynthesis protein B; Function of homologous gene experimentally demonstrated in an other organism; enzyme. (304 aa) |
| | purT | Phosphoribosylglycinamide formyltransferase 2; Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate; Belongs to the PurK/PurT family. (391 aa) |
| | thiE | Thiamine-phosphate pyrophosphorylase; Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP). Belongs to the thiamine-phosphate synthase family. (210 aa) |
| | thiM | Hydoxyethylthiazole kinase; Catalyzes the phosphorylation of the hydroxyl group of 4- methyl-5-beta-hydroxyethylthiazole (THZ); Belongs to the Thz kinase family. (267 aa) |
| | ABZ98784.1 | Hypothetical protein; No homology to any previously reported sequences. (418 aa) |
| | ABZ98780.1 | Putative transcriptional regulator, NadR family; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative regulator. (347 aa) |
| | ABZ98723.1 | Conserved hypothetical protein; Homologs of previously reported genes of unknown function. (74 aa) |
| | ABZ98717.1 | Putative acyltransferase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. (292 aa) |
| | pyrH | Uridylate kinase; Catalyzes the reversible phosphorylation of UMP to UDP. (248 aa) |
| | cdsA | Phosphatidate cytidylyltransferase (CDP-diglyceride synthetase); Function of homologous gene experimentally demonstrated in an other organism; enzyme. (303 aa) |
| | dxr | 1-deoxy-D-xylulose 5-phosphate reductoisomerase 2; Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4- phosphate (MEP); Belongs to the DXR family. (386 aa) |
| | dxs | 1-deoxy-D-xylulose-5-phosphate synthase; Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D- xylulose-5-phosphate (DXP); Belongs to the transketolase family. DXPS subfamily. (629 aa) |
| | cmk | CK; Cytidine monophosphate kinase; CMP kinase); Function of homologous gene experimentally demonstrated in an other organism; enzyme. (250 aa) |
| | rpsA | 30S ribosomal protein S1; Binds mRNA; thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence. (566 aa) |
| | plsX | Fatty acid/phospholipid synthesis protein PlsX; Catalyzes the reversible formation of acyl-phosphate (acyl- PO(4)) from acyl-[acyl-carrier-protein] (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA. (340 aa) |
| | ABZ98656.1 | Hypothetical protein; No homology to any previously reported sequences. (257 aa) |
| | lpxD | UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase; Function of homologous gene experimentally demonstrated in an other organism; enzyme. (339 aa) |
| | ABZ98593.1 | Putative adenylate cyclase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. (396 aa) |
| | ABZ98530.1 | Hypothetical protein; No homology to any previously reported sequences. (257 aa) |
| | pyrE | Orotate phosphoribosyltransferase (OPRT; Catalyzes the transfer of a ribosyl phosphate group from 5- phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP). (185 aa) |
| | ABZ98506.1 | Putative adenylate or guanylate cyclase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. (410 aa) |
| | ABZ98502.1 | Putative adenylate or guanylate cyclase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. (684 aa) |
| | nadC | Nicotinate-nucleotide pyrophosphorylase (carboxylating); Function of homologous gene experimentally demonstrated in an other organism; putative enzyme; Belongs to the NadC/ModD family. (287 aa) |
| | thiC | Thiamine biosynthesis protein ThiC; Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction. Belongs to the ThiC family. (524 aa) |
| | ABZ98286.1 | Hypothetical protein; No homology to any previously reported sequences. (402 aa) |
| | purL | Phosphoribosylformylglycinamidine synthase II (FGAM synthase II); Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is [...] (748 aa) |
| | ABZ98230.1 | Adenylate/guanylate cyclase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (430 aa) |
| | cinA | Competence-damage inducible protein CinA; Function of homologous gene experimentally demonstrated in an other organism; factor; Belongs to the CinA family. (417 aa) |
| | ABZ98175.1 | Putative phospholipase D; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. (544 aa) |
| | lpxB | Lipid-A-disaccharide synthase; Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. (372 aa) |
| | ABZ98163.1 | Conserved hypothetical protein; Homologs of previously reported genes of unknown function. (288 aa) |
| | ABZ98145.1 | Putative acyltransferase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. (382 aa) |
| | adk | Adenylate kinase (ATP-AMP transphosphorylase); Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family. (186 aa) |
| | gpsA1 | Glycerol-3-phosphate dehydrogenase [NAD(P)+] (NAD(P)H-dependent glycerol-3-phosphate dehydrogenase); Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family. (672 aa) |
| | purA | Adenylosuccinate synthetase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family. (424 aa) |
| | purC | Phosphoribosylaminoimidazole-succinocarboxamide synthase (SAICAR synthetase); Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the SAICAR synthetase family. (285 aa) |
| | purS | Phosphorybosylformylglycinamidine synthase PurS component; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is though [...] (82 aa) |
| | purQ | Phosphoribosylformylglycinamidine synthase I (FGAM synthase I); Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is t [...] (215 aa) |
| | lpxC | UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase (UDP-3-O-acyl-GlcNAc deacetylase); Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis; Belongs to the LpxC family. (302 aa) |
| | ABZ97886.1 | Conserved hypothetical protein; Homologs of previously reported genes of unknown function. (201 aa) |
| | nadD | Putative nicotinate-nucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD). (196 aa) |
| | dfpB | Phosphopantothenate--cysteine ligase; Phosphopantothenoylcysteine synthase; PPC synthetase; PPCS; CoaB; Function of homologous gene experimentally demonstrated in an other organism; enzyme. (225 aa) |
| | dfpA | Phosphopantothenoylcysteine decarboxylase (PPCDC; Function of homologous gene experimentally demonstrated in an other organism; enzyme. (176 aa) |
| | ABZ96829.1 | Hypothetical protein; No homology to any previously reported sequences. (352 aa) |
| | lpxD2 | UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase; Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3- hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. Belongs to the transferase hexapeptide repeat family. LpxD subfamily. (352 aa) |
| | ABZ96724.1 | Putative acyltransferase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. (240 aa) |
| | ABZ96690.1 | Putative phospholipid/glycerol acyltransferase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. (267 aa) |
| | ABZ96684.1 | Putative adenylate/guanylate cyclase, family 3; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. (617 aa) |
| | rfbA | Glucose-1-phosphate thymidylyltransferase; Function of homologous gene experimentally demonstrated in an other organism; enzyme. (343 aa) |
| | nadB | L-aspartate oxidase (LASPO; Catalyzes the oxidation of L-aspartate to iminoaspartate. (533 aa) |
| | ABZ96499.1 | Hypothetical protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology. (533 aa) |
| | lpxA | Acyl-[acyl-carrier-protein]--UDP-N- acetylglucosamine O-acyltransferase; Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. (268 aa) |
