(9 nodes) Thiamin diphosphate-binding fold network (Leptospira biflexa)

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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second shell of interactors

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proteins of unknown 3D structure

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Your Input:
	acoB	Pyruvate dehydrogenase E1 beta subunit; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2. (324 aa)
	acoA	Pyruvate dehydrogenase E1 alpha subunit; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). (322 aa)
	ilvB2	AHAS; Acetohydroxy-acid synthase large subunit; ALS); Function of homologous gene experimentally demonstrated in an other organism; enzyme. (575 aa)
	ilvB1	AHAS-I; Acetohydroxy-acid synthase I large subunit; ALS-I; Function of homologous gene experimentally demonstrated in an other organism; enzyme. (573 aa)
	ilvI	AHAS; Acetohydroxy-acid synthase large subunit; ALS; Function of homologous gene experimentally demonstrated in an other organism; enzyme. (587 aa)
	ABZ96777.1	Putative transketolase (TK); Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. (270 aa)
	dxs	1-deoxy-D-xylulose-5-phosphate synthase; Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D- xylulose-5-phosphate (DXP); Belongs to the transketolase family. DXPS subfamily. (629 aa)
	sucA	2-oxoglutarate dehydrogenase E1 component (Alpha-ketoglutarate dehydrogenase); Function of homologous gene experimentally demonstrated in an other organism; enzyme. (922 aa)
	ABZ99035.1	Putative transketolase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. (321 aa)

Your Current Organism:

Leptospira biflexa

NCBI taxonomy Id: 456481
Other names: L. biflexa serovar Patoc strain 'Patoc 1 (Paris)', Leptospira biflexa serovar Patoc str. ATCC 23582, Leptospira biflexa serovar Patoc strain 'Patoc 1 (Paris)', Leptospira biflexa serovar Patoc strain Patoc 1

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ABZ96777.1	ABZ99035.1	LEPBI_I0644	LEPBI_I2967	Putative transketolase (TK); Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.	Putative transketolase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.	0.999
ABZ96777.1	acoA	LEPBI_I0644	LEPBI_I1559	Putative transketolase (TK); Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.	Pyruvate dehydrogenase E1 alpha subunit; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).	0.811
ABZ96777.1	acoB	LEPBI_I0644	LEPBI_I1558	Putative transketolase (TK); Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.	Pyruvate dehydrogenase E1 beta subunit; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2.	0.826
ABZ99035.1	ABZ96777.1	LEPBI_I2967	LEPBI_I0644	Putative transketolase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.	Putative transketolase (TK); Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.	0.999
ABZ99035.1	acoA	LEPBI_I2967	LEPBI_I1559	Putative transketolase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.	Pyruvate dehydrogenase E1 alpha subunit; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).	0.811
ABZ99035.1	acoB	LEPBI_I2967	LEPBI_I1558	Putative transketolase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.	Pyruvate dehydrogenase E1 beta subunit; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2.	0.811
acoA	ABZ96777.1	LEPBI_I1559	LEPBI_I0644	Pyruvate dehydrogenase E1 alpha subunit; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).	Putative transketolase (TK); Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.	0.811
acoA	ABZ99035.1	LEPBI_I1559	LEPBI_I2967	Pyruvate dehydrogenase E1 alpha subunit; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).	Putative transketolase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.	0.811
acoA	acoB	LEPBI_I1559	LEPBI_I1558	Pyruvate dehydrogenase E1 alpha subunit; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).	Pyruvate dehydrogenase E1 beta subunit; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2.	0.999
acoA	ilvB1	LEPBI_I1559	LEPBI_I0792	Pyruvate dehydrogenase E1 alpha subunit; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).	AHAS-I; Acetohydroxy-acid synthase I large subunit; ALS-I; Function of homologous gene experimentally demonstrated in an other organism; enzyme.	0.826
acoA	ilvB2	LEPBI_I1559	LEPBI_I2362	Pyruvate dehydrogenase E1 alpha subunit; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).	AHAS; Acetohydroxy-acid synthase large subunit; ALS); Function of homologous gene experimentally demonstrated in an other organism; enzyme.	0.826
acoA	ilvI	LEPBI_I1559	LEPBI_I0605	Pyruvate dehydrogenase E1 alpha subunit; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).	AHAS; Acetohydroxy-acid synthase large subunit; ALS; Function of homologous gene experimentally demonstrated in an other organism; enzyme.	0.826
acoA	sucA	LEPBI_I1559	LEPBI_I1056	Pyruvate dehydrogenase E1 alpha subunit; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).	2-oxoglutarate dehydrogenase E1 component (Alpha-ketoglutarate dehydrogenase); Function of homologous gene experimentally demonstrated in an other organism; enzyme.	0.831
acoB	ABZ96777.1	LEPBI_I1558	LEPBI_I0644	Pyruvate dehydrogenase E1 beta subunit; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2.	Putative transketolase (TK); Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.	0.826
acoB	ABZ99035.1	LEPBI_I1558	LEPBI_I2967	Pyruvate dehydrogenase E1 beta subunit; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2.	Putative transketolase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.	0.811
acoB	acoA	LEPBI_I1558	LEPBI_I1559	Pyruvate dehydrogenase E1 beta subunit; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2.	Pyruvate dehydrogenase E1 alpha subunit; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).	0.999
acoB	ilvB1	LEPBI_I1558	LEPBI_I0792	Pyruvate dehydrogenase E1 beta subunit; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2.	AHAS-I; Acetohydroxy-acid synthase I large subunit; ALS-I; Function of homologous gene experimentally demonstrated in an other organism; enzyme.	0.827
acoB	ilvB2	LEPBI_I1558	LEPBI_I2362	Pyruvate dehydrogenase E1 beta subunit; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2.	AHAS; Acetohydroxy-acid synthase large subunit; ALS); Function of homologous gene experimentally demonstrated in an other organism; enzyme.	0.827
acoB	ilvI	LEPBI_I1558	LEPBI_I0605	Pyruvate dehydrogenase E1 beta subunit; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2.	AHAS; Acetohydroxy-acid synthase large subunit; ALS; Function of homologous gene experimentally demonstrated in an other organism; enzyme.	0.827
acoB	sucA	LEPBI_I1558	LEPBI_I1056	Pyruvate dehydrogenase E1 beta subunit; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2.	2-oxoglutarate dehydrogenase E1 component (Alpha-ketoglutarate dehydrogenase); Function of homologous gene experimentally demonstrated in an other organism; enzyme.	0.895

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