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| | ANS84067.1 | Thiol:disulfide interchange protein DsbA; Involved in disulfide-bond formation. Required for the functional maturation of secreted virulence factors. Acts by transferring its disulfide bond to other proteins. Belongs to the thioredoxin family. DsbA subfamily; Contains 1 thioredoxin domain. (200 aa) |
| | lpxL | Kdo(2)-lipid IV(A) lauroyltransferase; Catalyzes the transfer of laurate from lauroyl-acyl carrier protein (ACP) to Kdo(2)-lipid IV(A) to form Kdo(2)-(lauroyl)-lipid IV(A). (316 aa) |
| | ANS84152.1 | Uncharacterized protein; KEGG: hpk:Hprae_0259 heptosyltransferase I; Glycosyltransferases. (343 aa) |
| | waaE | Belongs to the glycosyltransferase 2 family. WaaE/KdtX subfamily; KEGG: vcx:VAA049_3477 (heptosyl)LPS beta-1,4-glucosyltransferase; Hexosyltransferases; overlaps another CDS with the same product name. (264 aa) |
| | opsX | Belongs to the glycosyltransferase 9 family; KEGG: vvu:VV1_0816 heptosyltransferase I; Glycosyltransferases; overlaps another CDS with the same product name. (352 aa) |
| | kdtA | Lipid IV(A) 3-deoxy-D-manno-octulosonic acid transferase; Involved in lipopolysaccharide (LPS) biosynthesis. Catalyzes the transfer of 3-deoxy-D-manno-octulosonate (Kdo) residue(s) from CMP- Kdo to lipid IV(A), the tetraacyldisaccharide-1,4'-bisphosphate precursor of lipid A; Belongs to the glycosyltransferase group 1 family. (432 aa) |
| | waaF | ADP-heptose--LPS heptosyltransferase; Belongs to the glycosyltransferase 9 family; KEGG: vch:VC0236 heptosyltransferase II; Glycosyltransferases. (352 aa) |
| | lpxM | Lauroyl-Kdo(2)-lipid IV(A) myristoyltransferase; Catalyzes the transfer of myristate from myristoyl-acyl carrier protein (ACP) to Kdo(2)-(lauroyl)-lipid IV(A) to form Kdo(2)- lipid A. (330 aa) |
| | gmhD | ADP-glyceromanno-heptose 6-epimerase; Catalyzes the interconversion between ADP-D-glycero-beta-D- manno-heptose and ADP-L-glycero-beta-D-manno-heptose via an epimerization at carbon 6 of the heptose; Belongs to the NAD(P)-dependent epimerase/dehydratase family. HldD subfamily. (313 aa) |
| | ANS84220.1 | Hypothetical protein. (174 aa) |
| | ANS84340.1 | Magnesium transporter MgtE; Acts as a magnesium transporter. (451 aa) |
| | ANS84341.1 | Phosphocarrier protein NPr; Component of the phosphoenolpyruvate-dependent nitrogen- metabolic phosphotransferase system (nitrogen-metabolic PTS), that seems to be involved in regulating nitrogen metabolism. The phosphoryl group from phosphoenolpyruvate (PEP) is transferred to the phosphoryl carrier protein NPr by enzyme I-Ntr. Phospho-NPr then transfers it to EIIA-Ntr. Could function in the transcriptional regulation of sigma-54 dependent operons in conjunction with the NPr (PtsO) and EIIA-Ntr (PtsN) proteins (By similarity); Belongs to the HPr family; Contains 1 HPr domain. (92 aa) |
| | ANS84342.1 | RNase adapter protein RapZ; Displays ATPase and GTPase activities. (287 aa) |
| | ptsN | Protein-N(pi)-phosphohistidine--sugar phosphotransferase; Seems to have a role in regulating nitrogen assimilation; Contains 1 PTS EIIA type-2 domain; KEGG: pmr:PMI3646 PTS system, nitrogen regulatory IIA component. (148 aa) |
| | ANS84344.1 | Ribosome hibernation promoting factor; During stationary phase, promotes and stabilizes dimerization of 70S ribosomes, leading to the formation of inactive 100S ribosomes; Belongs to the Hpf/RaiA ribosome-associated protein family. Hpf subfamily. (95 aa) |
| | lptB | Lipopolysaccharide export system ATP-binding protein LptB; Part of the ABC transporter complex LptBFG involved in the translocation of lipopolysaccharide (LPS) from the inner membrane to the outer membrane. Probably responsible for energy coupling to the transport system (By similarity); Belongs to the ABC transporter superfamily. Outer membrane lipopolysaccharide export (TC 1. B. 42) family; Contains 1 ABC transporter domain; KEGG: vch:VC2528 lipopolysaccharide export system ATP-binding protein; Acting on acid anhydrides; catalyzing transmembrane movement of substances. (241 aa) |
| | lptA | Lipopolysaccharide export system protein LptA; Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm. (165 aa) |
| | lptC | Hypothetical protein; Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. Facilitates the transfer of LPS from the inner membrane to the periplasmic protein LptA. Could be a docking site for LptA. Belongs to the LptC family. (187 aa) |
| | kdsC | 3-deoxy-manno-octulosonate-8-phosphatase; Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8- phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate; Belongs to the KdsC family. (185 aa) |
| | kdsD | Arabinose-5-phosphate isomerase; Belongs to the SIS family. GutQ/KpsF subfamily; Contains 2 CBS domains; Contains 1 SIS domain; KEGG: vcy:IX92_01075 arabinose-5-phosphate isomerase. (321 aa) |
| | ANS84351.1 | Inner membrane protein; Belongs to the sodium/potassium/calcium exchanger family. (321 aa) |
| | ANS84352.1 | Zinc import ATP-binding protein ZnuC; Part of the ABC transporter complex ZnuABC involved in zinc import. Responsible for energy coupling to the transport system; Belongs to the ABC transporter superfamily. Zinc importer (TC 3. A. 1. 15. 5) family; Contains 1 ABC transporter domain. (279 aa) |
| | ANS84353.1 | Putative phospholipid ABC transporter permease protein MlaE; Part of the ABC transporter complex MlaFEDB that actively prevents phospholipid accumulation at the cell surface. Probably maintains lipid asymmetry in the outer membrane by retrograde trafficking of phospholipids from the outer membrane to the inner membrane (By similarity); Belongs to the MlaE permease family. (263 aa) |
| | ANS84354.1 | Putative phospholipid ABC transporter-binding protein MlaD; Part of the ABC transporter complex MlaFEDB that actively prevents phospholipid accumulation at the cell surface. Probably maintains lipid asymmetry in the outer membrane by retrograde trafficking of phospholipids from the outer membrane to the inner membrane (By similarity); Belongs to the MlaD family. (162 aa) |
| | ANS84355.1 | Putative phospholipid-binding protein MlaC; Actively prevents phospholipid accumulation at the cell surface. Probably maintains lipid asymmetry in the outer membrane by retrograde trafficking of phospholipids from the outer membrane to the inner membrane. May transfer phospholipid across the periplasmic space and deliver it to the MlaFEDB complex at the inner membrane; Belongs to the MlaC/ttg2D family. (212 aa) |
| | ANS84356.1 | Hypothetical protein. (104 aa) |
| | ANS84357.1 | Involved in cell resistance against acid stress; Belongs to the BolA/IbaG family. (84 aa) |
| | apaG | Contains 1 apaG domain. (126 aa) |
| | ksgA | 16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))- dimethyltransferase; Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits. (268 aa) |
| | pdxA | 4-hydroxythreonine-4-phosphate dehydrogenase; Catalyzes the NAD(P)-dependent oxidation of 4-(phosphooxy)-L- threonine (HTP) into 2-amino-3-oxo-4-(phosphooxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP). (329 aa) |
| | surA | Peptidylprolyl isomerase; Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation. (431 aa) |
| | lptD | LPS-assembly protein LptD; Together with LptE, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. (790 aa) |
| | ANS84454.1 | Lipopolysaccharide export system permease protein LptF; Part of the ABC transporter complex LptBFG involved in the translocation of lipopolysaccharide (LPS) from the inner membrane to the outer membrane; Belongs to the LptF/LptG family. (367 aa) |
| | ANS84455.1 | Lipopolysaccharide export system permease protein LptG; Part of the ABC transporter complex LptBFG involved in the translocation of lipopolysaccharide (LPS) from the inner membrane to the outer membrane; Belongs to the LptF/LptG family. (356 aa) |
| | dsbC | Protein disulfide-isomerase; Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process; Belongs to the thioredoxin family. DsbC subfamily. (248 aa) |
| | ANS84484.1 | Lysophospholipase NTE1; Intracellular phospholipase B that catalyzes the double deacylation of phosphatidylcholine (PC) to glycerophosphocholine (GroPCho). Plays an important role in membrane lipid homeostasis. Responsible for the rapid PC turnover in response to inositol, elevated temperatures, or when choline is present in the growth medium (By similarity); Belongs to the NTE family; Contains 2 cyclic nucleotide-binding domains; Contains 1 patatin domain. (760 aa) |
| | ptsP | Component of the phosphoenolpyruvate-dependent nitrogen- metabolic phosphotransferase system (nitrogen-metabolic PTS), that seems to be involved in regulating nitrogen metabolism. Enzyme I- Ntr transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (NPr). Could function in the transcriptional regulation of sigma-54 dependent operons in conjunction with the NPr (PtsO) and EIIA-Ntr (PtsN) proteins; Belongs to the PEP-utilizing enzyme family; Contains 1 GAF domain; KEGG: eta:ETA_27610 phosphotransferase system, enzyme I, PtsP. (748 aa) |
| | bamD | Outer membrane protein assembly factor BamD; Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane. (241 aa) |
| | ANS84588.1 | Hypothetical protein. (110 aa) |
| | ANS84589.1 | Hypothetical protein. (126 aa) |
| | bamA | Outer membrane protein assembly factor BamA; Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane. (800 aa) |
| | ANS84662.1 | Chaperone protein Skp; Molecular chaperone that interacts specifically with outer membrane proteins, thus maintaining the solubility of early folding intermediates during passage through the periplasm. (169 aa) |
| | lpxD | UDP-3-O-(3-hydroxymyristoyl)glucosamine N-acyltransferase; Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3- hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. Belongs to the transferase hexapeptide repeat family. LpxD subfamily. (343 aa) |
| | fabZ | 3-hydroxyacyl-[acyl-carrier-protein] dehydratase; Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs. (150 aa) |
| | lpxA | Acyl-[acyl-carrier-protein]--UDP-N- acetylglucosamine O-acyltransferase; Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. (262 aa) |
| | lpxB | Lipid-A-disaccharide synthase; Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. (383 aa) |
| | ANS84676.1 | Uncharacterized protein. (248 aa) |
| | gmhA | D-sedoheptulose 7-phosphate isomerase; Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate. (192 aa) |
| | gmhB | D-glycero-beta-D-manno-heptose 1,7-bisphosphate 7-phosphatase; Converts the D-glycero-beta-D-manno-heptose 1,7- bisphosphate intermediate into D-glycero-beta-D-manno-heptose 1- phosphate by removing the phosphate group at the C-7 position; Belongs to the GmhB family; KEGG: vch:VC0908 D-glycero-D-manno-heptose 1,7-bisphosphate phosphatase. (183 aa) |
| | lptE | LPS-assembly lipoprotein LptE; Together with LptD, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. Required for the proper assembly of LptD. Binds LPS and may serve as the LPS recognition site at the outer membrane. (220 aa) |
| | ANS84724.1 | Chitoporin; Involved in the uptake of chitosugars; Belongs to the Gram-negative porin family. (367 aa) |
| | ANS84747.1 | Chitoporin; Involved in the uptake of chitosugars; Belongs to the Gram-negative porin family. (359 aa) |
| | ANS84750.1 | Outer membrane protein A; Required for the action of colicins K and L and for the stabilization of mating aggregates in conjugation. Serves as a receptor for a number of T-even like phages. Also acts as a porin with low permeability that allows slow penetration of small solutes (By similarity); Belongs to the OmpA family; Contains 1 OmpA-like domain; Belongs to the outer membrane OOP (TC 1.B.6) superfamily. (320 aa) |
| | kdsA | 3-deoxy-8-phosphooctulonate synthase; Belongs to the KdsA family; KEGG: eca:ECA2194 2-dehydro-3-deoxyphosphooctonate aldolase (KDO 8-P synthase). (283 aa) |
| | bamC | Outer membrane protein assembly factor BamC; Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane. (340 aa) |
| | ANS84819.1 | Sodium-type flagellar protein MotY; Plays the role of a stator in the sodium flagellar motor, stabilizing the force-generating unit through direct interaction with the cell wall. Involved in adherence and invasion of fish cell line. Belongs to the OmpA family; Contains 1 OmpA-like domain. (317 aa) |
| | ppiD | Peptidylprolyl isomerase; PPIases accelerate the folding of proteins; Contains 1 PpiC domain; KEGG: vch:VC1918 peptidyl-prolyl cis-trans isomerase D. (619 aa) |
| | lolA | Outer-membrane lipoprotein carrier protein; Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane). (198 aa) |
| | dsbB | Disulfide bond formation protein B; Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein; Belongs to the DsbB family. (173 aa) |
| | ANS85125.1 | Hypothetical protein. (255 aa) |
| | mfd | Transcription-repair-coupling factor; Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site; In the C-terminal section; belongs to the helicase family. RecG subfamily. (1154 aa) |
| | ANS85127.1 | Hypothetical protein. (188 aa) |
| | ANS85128.1 | Lipoprotein-releasing system transmembrane protein LolC; Part of an ATP-dependent transport system responsible for the release of lipoproteins targeted to the outer membrane from the inner membrane. Such a release is dependent of the sorting-signal (absence of an Asp at position 2 of the mature lipoprotein) and of LolA (By similarity); Belongs to the ABC-4 integral membrane protein family. LolC/E subfamily. (402 aa) |
| | lolD | Macrolide export ATP-binding/permease protein MacB; Part of the ABC transporter complex LolCDE involved in the translocation of lipoproteins, in an ATP-dependent manner. (228 aa) |
| | ANS85130.1 | Lipoprotein-releasing system transmembrane protein LolC; Part of an ATP-dependent transport system responsible for the release of lipoproteins targeted to the outer membrane from the inner membrane. Such a release is dependent of the sorting-signal (absence of an Asp at position 2 of the mature lipoprotein) and of LolA (By similarity); Belongs to the ABC-4 integral membrane protein family. LolC/E subfamily. (414 aa) |
| | msbA | Lipid A export ATP-binding/permease protein MsbA; Involved in lipid A export and possibly also in glycerophospholipid export and for biogenesis of the outer membrane. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation. (583 aa) |
| | lpxK | Tetraacyldisaccharide 4'-kinase; Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1-P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA). (335 aa) |
| | ANS85135.1 | Belongs to the UPF0434 family. (59 aa) |
| | kdsB | 3-deoxy-manno-octulosonate cytidylyltransferase; Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria. (249 aa) |
| | ANS85163.1 | Thiol:disulfide interchange protein DsbA; Required for disulfide bond formation in some periplasmic proteins such as PhoA or OmpA. Acts by transferring its disulfide bond to other proteins and is reduced in the process. DsbA is reoxidized by DsbB. It is required for pilus biogenesis. Belongs to the thioredoxin family. DsbA subfamily; Contains 1 thioredoxin domain. (206 aa) |
| | ANS85283.1 | Internalin-J; Involved in several steps of L. monocytogenes infection; Contains 14 LRR (leucine-rich) repeats; Contains 4 MucBP domains. (472 aa) |
| | ANS85284.1 | Hypothetical protein. (235 aa) |
| | ANS85405.1 | Hypothetical protein. (116 aa) |
| | ANS85406.1 | Outer membrane protein P.III; Belongs to the OmpA family; Contains 1 OmpA-like domain. (203 aa) |
| | ANS85407.1 | Outer membrane efflux protein BepC; Involved in the efflux of toxic and relatively hydrophobic compounds. Influences survival inside the host; Belongs to the outer membrane factor (OMF) (TC 1. B. 17) family. (435 aa) |
| | ANS85534.1 | Hypothetical protein. (278 aa) |
| | ANS85598.1 | Outer membrane protein P.III; Belongs to the OmpA family; Contains 1 OmpA-like domain. (207 aa) |
| | cpoB | Uncharacterized protein; Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division; Belongs to the CpoB family. (257 aa) |
| | pal | Peptidoglycan-associated lipoprotein; Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity. (171 aa) |
| | tolB | Protein TolB; Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity. (450 aa) |
| | ANS85903.1 | Coiled-coil domain-containing protein 88B; Belongs to the CCDC88 family. (361 aa) |
| | tolR | Protein TolR; Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity. (147 aa) |
| | tolQ | Hypothetical protein; Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity. (227 aa) |
| | ybgC | Acyl-CoA thioester hydrolase; Thioesterase that appears to be involved in phospholipid metabolism. Some specific acyl-ACPs could be physiological substrates. Displays acyl-CoA thioesterase activity on malonyl-CoA in vitro, catalyzing the hydrolysis of the thioester bond (By similarity); Belongs to the 4-hydroxybenzoyl-CoA thioesterase family; KEGG: eco:b0736 acyl-CoA thioester hydrolase; Thiolester hydrolases. (139 aa) |
| | ANS85907.1 | Hypothetical protein. (100 aa) |
| | lpxH | UDP-2,3-diacylglucosamine diphosphatase; Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. (257 aa) |
| | prmB | Ribosomal protein L3 N(5)-glutamine methyltransferase; Specifically methylates the 50S ribosomal protein L3 on a specific glutamine residue; Belongs to the protein N5-glutamine methyltransferase family. PrmB subfamily. (310 aa) |
| | ANS86051.1 | Belongs to the UPF0115 family; Contains 1 Smr domain. (176 aa) |
| | bamE | Outer membrane protein assembly factor BamE; Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane. (127 aa) |
| | ANS86183.1 | Belongs to the UPF0125 (RnfH) family. (117 aa) |
| | ANS86184.1 | Persistence and stress-resistance toxin PasT; Toxic component of a toxin-antitoxin (TA) module. Binds to 50S ribosomal subunits, preventing them from associating with 30S subunits to form 70S ribosomes (By similarity). In this strain of E. coli low levels of PasT complement operon disruption, however high levels are toxi; their effects are abrogated by high level expression of cognate antitoxin PasI. Plays a role in persistence after antibiotic exposure and survival of nitrosative stres; the toxic and persistence phenotypes are conferred by the same N- terminal region of the protein, w [...] (147 aa) |
| | bamB | Outer membrane protein assembly factor BamB; Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane. (386 aa) |
| | ANS86208.1 | UPF0070 protein YfgM; Belongs to the UPF0070 family. (204 aa) |
| | ANS86263.1 | Peptidoglycan-associated lipoprotein; Thought to play a role in bacterial envelope integrity. Very strongly associated with the peptidoglycan (By similarity); Belongs to the OmpA family. Pal subfamily; Contains 1 OmpA-like domain. (212 aa) |
| | ANS86305.1 | UPF0721 transmembrane protein; Belongs to the UPF0721 family. (224 aa) |
| | lpxC | UDP-3-O-acyl-N-acetylglucosamine deacetylase; Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis; Belongs to the LpxC family. (305 aa) |
| | ANS86332.1 | Stringent starvation protein; Seems to act in concert with SspA in the regulation of several proteins during exponential and stationary-phase growth. The exact function of SspB is not yet known (By similarity); Belongs to the SspB family. (158 aa) |
| | ANS86333.1 | Stringent starvation protein; Forms an equimolar complex with the RNA polymerase holoenzyme (RNAP) but not with the core enzyme; Belongs to the GST superfamily. HSP26 family; Contains 1 GST C-terminal domain; Contains 1 GST N-terminal domain. (211 aa) |
| | degP | Peptidase Do; DegQ could degrade transiently denatured and unfolded proteins which accumulate in the periplasm following stress conditions. DegQ is efficient with Val-Xaa and Ile-Xaa peptide bonds, suggesting a preference for a beta-branched side chain amino acids. Only unfolded proteins devoid of disulfide bonds appear capable to be cleaved, thereby preventing non-specific proteolysis of folded proteins. DegQ can substitute for the periplasmic protease DegP; Belongs to the peptidase S1C family; Contains 2 PDZ (DHR) domains; KEGG: vpa:VP0433 serine protease Do. (455 aa) |
| | hhoB | Serine endoprotease; A site-1 protease (S1P) that cleaves the peptide bond between 'Val-148' and 'Ser-149' in RseA. Part of a regulated intramembrane proteolysis (RIP) cascade. When heat shock or other environmental stresses disrupt protein folding in the periplasm, DegS senses the accumulation of unassembled outer membrane porins (OMP) and then initiates RseA (anti sigma-E factor) degradation by cleaving its periplasmic domain, making it a substrate for subsequent cleavage by RseP. This cascade ultimately leads to the sigma-E-driven expression of a variety of factors dealing with fold [...] (354 aa) |
| | gmhC | D-glycero-beta-D-manno-heptose-7-phosphate kinase; Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno-heptose. In the N-terminal section; belongs to the carbohydrate kinase PfkB family. (476 aa) |
| | zapD | Cell division protein ZapD; Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity. (246 aa) |
| | ANS86514.1 | Inner membrane protein YpjD. (264 aa) |
| | ANS86515.1 | UPF0053 inner membrane protein YfjD; Belongs to the UPF0053 family; Contains 2 CBS domains; Contains 1 DUF21 domain. (424 aa) |
| | rex2 | Oligoribonuclease; 3'-to-5' exoribonuclease specific for small oligoribonucleotides; Belongs to the oligoribonuclease family. (181 aa) |
| | dsbD | Protein-disulfide reductase; Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a cascade of disulfide bond formation and reduction steps. Belongs to the thioredoxin family. DsbD subfamily. (601 aa) |
| | ANS86722.1 | Involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space. It derives its energy for transport by interacting with the trans-periplasmic membrane protein TonB; Belongs to the TonB-dependent receptor family. BtuB (TC 1. B. 14. 3. 1) subfamily. (606 aa) |
| | ANS86865.1 | Hypothetical protein. (471 aa) |
| | ppiC | Peptidylprolyl isomerase; PPIases accelerate the folding of proteins. It prefers amino acid residues with hydrophobic side chains like leucine and phenylalanine in the P1 position of the peptides substrates (By similarity); Belongs to the PpiC/parvulin rotamase family; Contains 1 PpiC domain; KEGG: eca:ECA4216 peptidyl-prolyl cis-trans isomerase C. (92 aa) |
| | lpxL-2 | Kdo(2)-lipid IV(A) lauroyltransferase; Catalyzes the transfer of laurate from lauroyl-acyl carrier protein (ACP) to Kdo(2)-lipid IV(A) to form Kdo(2)-(lauroyl)-lipid IV(A). (310 aa) |
| | ANS87536.1 | Outer membrane lipoprotein Omp16 like protein; Belongs to the OmpA family. Pal subfamily; Contains 1 OmpA-like domain. (197 aa) |
| | ANS87562.1 | Hypothetical protein. (172 aa) |
| | ANS87563.1 | Hypothetical protein. (124 aa) |
| | ANS88037.1 | Major outer membrane lipoprotein; Interacts with the peptidoglycan both covalently and noncovalently; Belongs to the Lpp family. (82 aa) |
