STRINGSTRING
ANS87383.1 ANS87383.1 ANS87427.1 ANS87427.1 pyrE pyrE ANS87428.1 ANS87428.1 ANS87456.1 ANS87456.1 ANS88018.1 ANS88018.1 mrdB-2 mrdB-2 ANS88031.1 ANS88031.1 deoD-2 deoD-2 ANS84152.1 ANS84152.1 opsX opsX ANS84161.1 ANS84161.1 hisH hisH hisF hisF kdtA kdtA waaF waaF ANS84198.1 ANS84198.1 ANS84202.1 ANS84202.1 ANS84204.1 ANS84204.1 ANS84205.1 ANS84205.1 ANS84208.1 ANS84208.1 mrcA mrcA ANS84362.1 ANS84362.1 ANS84378.1 ANS84378.1 nadC nadC umpA umpA chbP chbP mrcB mrcB hprT hprT ANS84674.1 ANS84674.1 lpxB lpxB gpt gpt ANS84584.1 ANS84584.1 ANS84579.1 ANS84579.1 ANS84572.1 ANS84572.1 rlpA rlpA mrdB mrdB ANS84842.1 ANS84842.1 ANS84891.1 ANS84891.1 mltG mltG trpD trpD ANS85182.1 ANS85182.1 ANS85280.1 ANS85280.1 cobU cobU ANS85540.1 ANS85540.1 ANS85541.1 ANS85541.1 ANS85542.1 ANS85542.1 ANS85546.1 ANS85546.1 waaB waaB hasA hasA hisF-2 hisF-2 hisH-2 hisH-2 hisG hisG ANS85864.1 ANS85864.1 arnC arnC glgA glgA aprT aprT purF purF uprT uprT mltF mltF ANS86215.1 ANS86215.1 tgt tgt queA queA ANS86256.1 ANS86256.1 deoD deoD deoA deoA murG murG ftsW ftsW ftsI ftsI glgB glgB malQ malQ ANS86797.1 ANS86797.1 ANS86860.1 ANS86860.1 ppnP ppnP bcsA bcsA
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query proteins and first shell of interactors
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second shell of interactors
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proteins of unknown 3D structure
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a 3D structure is known or predicted
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ANS87383.1Pentapeptide repeat protein QnrB4; Probably plays a role in resistance to quinolone antibiotics. Only inhibits ATP-dependent DNA supercoiling by E. coli gyrase at high concentration (30 uM). Protects E. coli gyrase supercoiling activity from inhibition by fluoroquinolones (ciprofloxacin) at 0. 1 uM, does not protect M. tuberculosis gyrase activity ; Belongs to the pentapeptide repeat protein family; Contains 1 pentapeptide repeat domain. (221 aa)
ANS87427.14-alpha-glucanotransferase; Belongs to the disproportionating enzyme family; KEGG: vvu:VV2_1251 4-alpha-glucanotransferase. (726 aa)
pyrEOrotate phosphoribosyltransferase; Catalyzes the transfer of a ribosyl phosphate group from 5- phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP). (213 aa)
ANS87428.1Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties (By similarity); Belongs to the glycogen phosphorylase family; KEGG: puv:PUV_22600 starch phosphorylase. (817 aa)
ANS87456.1Cellulose synthase (UDP-forming); Catalytic subunit of cellulose synthase. It polymerizes uridine 5'-diphosphate glucose to cellulose. (878 aa)
ANS88018.1Uridine phosphorylase; Cleavage of guanosine or inosine to respective bases and sugar-1-phosphate molecules. Cleaves inosine, guanosine, and adenosine with a better efficiency than MTA; Belongs to the PNP/UDP phosphorylase family; KEGG: vpa:VPA1079 uridine phosphorylase. (243 aa)
mrdB-2Rod shape-determining protein RodA; Peptidoglycan polymerase that is essential for cell wall elongation; Belongs to the SEDS family. MrdB/RodA subfamily. (396 aa)
ANS88031.1Hypothetical protein. (99 aa)
deoD-2Belongs to the PNP/UDP phosphorylase family; KEGG: eco:b4384 purine-nucleoside phosphorylase. (236 aa)
ANS84152.1Uncharacterized protein; KEGG: hpk:Hprae_0259 heptosyltransferase I; Glycosyltransferases. (343 aa)
opsXBelongs to the glycosyltransferase 9 family; KEGG: vvu:VV1_0816 heptosyltransferase I; Glycosyltransferases; overlaps another CDS with the same product name. (352 aa)
ANS84161.1Hypothetical protein. (386 aa)
hisHImidazole glycerol phosphate synthase subunit HisH; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR; Contains 1 glutamine amidotransferase type-1 domain; KEGG: nis:NIS_1412 glutamine amidotransferase; Pentosyltransferases. (204 aa)
hisFPutative imidazole glycerol phosphate synthase subunit hisF2; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit (By similarity); Belongs to the HisA/HisF family; KEGG: pae:PA3151 cyclase; Oxo-acid-lyases. (251 aa)
kdtALipid IV(A) 3-deoxy-D-manno-octulosonic acid transferase; Involved in lipopolysaccharide (LPS) biosynthesis. Catalyzes the transfer of 3-deoxy-D-manno-octulosonate (Kdo) residue(s) from CMP- Kdo to lipid IV(A), the tetraacyldisaccharide-1,4'-bisphosphate precursor of lipid A; Belongs to the glycosyltransferase group 1 family. (432 aa)
waaFADP-heptose--LPS heptosyltransferase; Belongs to the glycosyltransferase 9 family; KEGG: vch:VC0236 heptosyltransferase II; Glycosyltransferases. (352 aa)
ANS84198.1Hypothetical protein. (331 aa)
ANS84202.1Hypothetical protein. (384 aa)
ANS84204.1Imidazole glycerol phosphate synthase subunit HisH; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR (By similarity); Contains 1 glutamine amidotransferase type-1 domain; KEGG: axy:AXYL_06292 glutamine amidotransferase; Pentosyltransferases. (205 aa)
ANS84205.1Putative imidazole glycerol phosphate synthase subunit hisF2; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit (By similarity); Belongs to the HisA/HisF family; KEGG: vvy:VV0356 cyclase; Oxo-acid-lyases. (253 aa)
ANS84208.1Hypothetical protein. (388 aa)
mrcAPenicillin-binding protein 1A; Cell wall formation. Synthesis of cross-linked peptidoglycan from the lipid intermediates. The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal domain (cross-linking of the peptide subunits) (By similarity); In the N-terminal sectio; belongs to the glycosyltransferase 51 family; In the C-terminal sectio; belongs to the transpeptidase family; KEGG: ddc:Dd586_3807 penicillin-binding protein 1A; Hexosyltransferases. (833 aa)
ANS84362.1Membrane-bound lytic murein transglycosylase; Murein-degrading enzyme. May play a role in recycling of muropeptides during cell elongation and/or cell division. (378 aa)
ANS84378.1Hypothetical protein. (589 aa)
nadCNicotinate-nucleotide diphosphorylase (carboxylating); Involved in the catabolism of quinolinic acid (QA); Belongs to the NadC/ModD family; KEGG: vch:VC2422 nicotinate-nucleotide pyrophosphorylase (carboxylating). (295 aa)
umpAProlipoprotein diacylglyceryl transferase; Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins; Belongs to the Lgt family. (274 aa)
chbPN,N'-diacetylchitobiose phosphorylase; Catalyzes the phosphorolysis of cellobiose, yielding glucose 1-phosphate and glucose. Is inactive against cellotriose and the disaccharides lactose, chitobiose and xylobiose. May be the primary enzyme for processing cellobiose in T. neapolitana; Belongs to the glycosyl hydrolase 94 family; KEGG: vch:VC0612 N,N'-diacetylchitobiose phosphorylase. (802 aa)
mrcBPenicillin-binding protein 1B; Cell wall formation. Synthesis of cross-linked peptidoglycan from the lipid intermediates. The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal domain (cross- linking of the peptide subunits). (788 aa)
hprTHypoxanthine phosphoribosyltransferase; Acts preferentially on hypoxanthin; has very low activity towards guanine. Inactive towards xanthine (By similarity); Belongs to the purine/pyrimidine phosphoribosyltransferase family; KEGG: ype:YPO3408 hypoxanthine phosphoribosyltransferase. (176 aa)
ANS84674.1Membrane-bound lytic murein transglycosylase D; Murein-degrading enzyme. May play a role in recycling of muropeptides during cell elongation and/or cell division (By similarity); Belongs to the transglycosylase Slt family; Contains 2 LysM repeats. (523 aa)
lpxBLipid-A-disaccharide synthase; Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. (383 aa)
gptXanthine phosphoribosyltransferase; Acts on guanine, xanthine and to a lesser extent hypoxanthine; Belongs to the purine/pyrimidine phosphoribosyltransferase family. XGPT subfamily. (154 aa)
ANS84584.1Laccase domain protein; Belongs to the LACC1 family; Belongs to the multicopper oxidase YfiH/RL5 family. (246 aa)
ANS84579.1Hypothetical protein; Murein-degrading enzyme that degrades murein glycan strands and insoluble, high-molecular weight murein sacculi, with the concomitant formation of a 1,6-anhydromuramoyl product. Lytic transglycosylases (LTs) play an integral role in the metabolism of the peptidoglycan (PG) sacculus. Their lytic action creates space within the PG sacculus to allow for its expansion as well as for the insertion of various structures such as secretion systems and flagella. In the N-terminal section; belongs to the bacterial solute- binding protein 3 family. (478 aa)
ANS84572.1Soluble lytic murein transglycosylase; Murein-degrading enzyme. Catalyzes the cleavage of the glycosidic bonds between N-acetylmuramic acid and N- acetylglucosamine residues in peptidoglycan. May play a role in recycling of muropeptides during cell elongation and/or cell division (By similarity); Belongs to the transglycosylase Slt family; KEGG: gps:C427_5355 soluble lytic murein transglycosylase; Glycosidases, i. e. enzymes hydrolyzing O- and S-glycosyl compounds. (651 aa)
rlpARlpA-like lipoprotein; Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides. (278 aa)
mrdBRod shape-determining protein RodA; Peptidoglycan polymerase that is essential for cell wall elongation; Belongs to the SEDS family. MrdB/RodA subfamily. (373 aa)
ANS84842.1Uridine phosphorylase; Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1-phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis. Belongs to the PNP/UDP phosphorylase family. (252 aa)
ANS84891.1Membrane-bound lytic murein transglycosylase. (324 aa)
mltGUPF0755 protein YceG; Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation. (338 aa)
trpDAnthranilate phosphoribosyltransferase; Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'- phosphoribosyl)-anthranilate (PRA). (332 aa)
ANS85182.1Anthranilate synthase; Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of am [...] (196 aa)
ANS85280.1Endo-type membrane-bound lytic murein transglycosylase A-like protein; Murein-degrading enzyme. May play a role in recycling of muropeptides during cell elongation and/or cell division (Potential); Belongs to the transglycosylase Slt family. (373 aa)
cobUNicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase; Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6-dimethylbenzimidazole (DMB). (342 aa)
ANS85540.1Hypothetical protein. (355 aa)
ANS85541.1Lipopolysaccharide core biosynthesis glycosyltransferase LpsE; Belongs to the glycosyltransferase group 1 family. Glycosyltransferase 4 subfamily; KEGG: vfi:VF_A1028 null; Hexosyltransferases. (404 aa)
ANS85542.1Hypothetical protein. (343 aa)
ANS85546.1Putative teichuronic acid biosynthesis glycosyltransferase TuaH; Belongs to the glycosyltransferase group 1 family; KEGG: vfi:VF_A1033 null; Hexosyltransferases. (313 aa)
waaBLipopolysaccharide core biosynthesis mannosyltransferase LpcC; Acts at transfer of mannose group to a 3-deoxy-D-mono octulonic acid (KDO) via an alpha-1,5 linkage. Belongs to the glycosyltransferase group 1 family. Glycosyltransferase 4 subfamily; KEGG: clt:CM240_1092 UDP-D-galactose:(glucosyl)LPS alpha-1,6-D-galactosyltransferase; Hexosyltransferases. (368 aa)
hasAKEGG: sht:KO02_15915 hyaluronan synthase. (393 aa)
hisF-2Imidazole glycerol phosphate synthase subunit hisF1; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit. (262 aa)
hisH-2Imidazole glycerol phosphate synthase subunit HisH; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF. (204 aa)
hisGATP phosphoribosyltransferase; Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity. Belongs to the ATP phosphoribosyltransferase family. Long subfamily. (298 aa)
ANS85864.1Hypothetical protein. (469 aa)
arnCUndecaprenyl-phosphate 4-deoxy-4-formamido-L-arabinose transferase; Involved in O antigen modification. Catalyzes the transfer of the glucose residue from UDP-glucose to a lipid carrier (By similarity); Belongs to the glycosyltransferase 2 family. GtrB subfamily; KEGG: cvi:CV_0749 undecaprenyl-phosphate 4-deoxy-4-formamido-L-arabinose transferase. (334 aa)
glgAStarch synthase; Synthesizes alpha-1,4-glucan chains using ADP-glucose. (485 aa)
aprTAdenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. (181 aa)
purFAmidophosphoribosyltransferase; Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine; In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family. (504 aa)
uprTUracil phosphoribosyltransferase; Catalyzes the conversion of uracil and 5-phospho-alpha-D- ribose 1-diphosphate (PRPP) to UMP and diphosphate. (208 aa)
mltFMembrane-bound lytic murein transglycosylase; Murein-degrading enzyme that degrades murein glycan strands and insoluble, high-molecular weight murein sacculi, with the concomitant formation of a 1,6-anhydromuramoyl product. Lytic transglycosylases (LTs) play an integral role in the metabolism of the peptidoglycan (PG) sacculus. Their lytic action creates space within the PG sacculus to allow for its expansion as well as for the insertion of various structures such as secretion systems and flagella. (521 aa)
ANS86215.1Membrane-bound lytic murein transglycosylase; Murein-degrading enzyme. May play a role in recycling of muropeptides during cell elongation and/or cell division. Degrades murein glycan strands and insoluble, high-molecular weight murein sacculi (By similarity). (366 aa)
tgttRNA-guanine(34) transglycosylase; Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, - Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form [...] (377 aa)
queAS-adenosylmethionine:tRNA ribosyltransferase-isomerase; Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA). (350 aa)
ANS86256.1Membrane-bound lytic murein transglycosylase; Murein-degrading enzyme. May play a role in recycling of muropeptides during cell elongation and/or cell division. (373 aa)
deoDBelongs to the PNP/UDP phosphorylase family; KEGG: eco:b4384 purine-nucleoside phosphorylase. (239 aa)
deoAThymidine phosphorylase; The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis. Belongs to the thymidine/pyrimidine-nucleoside phosphorylase family. (442 aa)
murGUndecaprenyldiphospho-muramoylpentapeptide beta-N-acetylglucosaminyltransferase; Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II); Belongs to the glycosyltransferase 28 family. MurG subfamily. (353 aa)
ftsWPutative lipid II flippase FtsW; Peptidoglycan polymerase that is essential for cell division. Belongs to the SEDS family. FtsW subfamily. (396 aa)
ftsIPeptidoglycan synthase FtsI; Catalyzes cross-linking of the peptidoglycan cell wall at the division septum; Belongs to the transpeptidase family. FtsI subfamily. (575 aa)
glgB1,4-alpha-glucan branching enzyme; Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position; Belongs to the glycosyl hydrolase 13 family. GlgB subfamily. (706 aa)
malQ4-alpha-glucanotransferase; Belongs to the disproportionating enzyme family; KEGG: mvs:MVIS_3183 4-alpha-glucanotransferase. (740 aa)
ANS86797.1Glycogen phosphorylase; Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties. (817 aa)
ANS86860.1Hypothetical protein. (525 aa)
ppnPUPF0345 protein; Catalyzes the phosphorolysis of diverse nucleosides, yielding D-ribose 1-phosphate and the respective free bases. Can use uridine, adenosine, guanosine, cytidine, thymidine, inosine and xanthosine as substrates. Also catalyzes the reverse reactions. (92 aa)
bcsACellulose synthase (UDP-forming); In the N-terminal sectio; belongs to the glycosyltransferase 2 family; In the C-terminal sectio; belongs to the AcsB/BcsB family; Contains 1 PilZ domain; KEGG: pgb:H744_2c1635 cellulose synthase (UDP-forming). (619 aa)
Your Current Organism:
Vibrio scophthalmi
NCBI taxonomy Id: 45658
Other names: CAIM 75, CECT 4638, CIP 105211, LMG 19158, LMG:19158, V. scophthalmi, strain A089
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