STRINGSTRING
EFL24626.1 EFL24626.1 EFL20313.1 EFL20313.1 EFL20381.1 EFL20381.1 EFL20395.1 EFL20395.1 EFL20399.1 EFL20399.1 EFL20404.1 EFL20404.1 EFL20405.1 EFL20405.1 glyA glyA EFL20479.1 EFL20479.1 EFL20655.1 EFL20655.1 EFL20687.1 EFL20687.1 EFL20691.1 EFL20691.1 EFL20710.1 EFL20710.1 EFL20712.1 EFL20712.1 EFL20762.1 EFL20762.1 EFL20795.1 EFL20795.1 EFL20798.1 EFL20798.1 EFL20814.1 EFL20814.1 EFL20920.1 EFL20920.1 EFL21007.1 EFL21007.1 pfkA pfkA EFL21069.1 EFL21069.1 EFL21130.1 EFL21130.1 EFL21131.1 EFL21131.1 EFL21189.1 EFL21189.1 EFL21238.1 EFL21238.1 icmF icmF EFL21243.1 EFL21243.1 EFL21255.1 EFL21255.1 EFL21263.1 EFL21263.1 EFL21280.1 EFL21280.1 EFL21298.1 EFL21298.1 EFL21312.1 EFL21312.1 EFL21377.1 EFL21377.1 EFL21417.1 EFL21417.1 EFL21454.1 EFL21454.1 EFL21501.1 EFL21501.1 EFL21508.1 EFL21508.1 EFL21526.1 EFL21526.1 EFL21605.1 EFL21605.1 EFL21701.1 EFL21701.1 EFL21717.1 EFL21717.1 EFL21744.1 EFL21744.1 EFL21784.1 EFL21784.1 EFL21786.1 EFL21786.1 EFL21944.1 EFL21944.1 EFL21995.1 EFL21995.1 EFL22081.1 EFL22081.1 EFL22104.1 EFL22104.1 EFL22158.1 EFL22158.1 EFL22209.1 EFL22209.1 EFL22210.1 EFL22210.1 EFL22254.1 EFL22254.1 EFL22321.1 EFL22321.1 EFL22342.1 EFL22342.1 EFL22346.1 EFL22346.1 EFL22347.1 EFL22347.1 EFL22377.1 EFL22377.1 EFL22378.1 EFL22378.1 EFL22389.1 EFL22389.1 EFL22414.1 EFL22414.1 EFL22418.1 EFL22418.1 EFL22433.1 EFL22433.1 EFL22434.1 EFL22434.1 EFL22456.1 EFL22456.1 EFL22469.1 EFL22469.1 EFL22493.1 EFL22493.1 EFL22575.1 EFL22575.1 EFL22612.1 EFL22612.1 EFL22620.1 EFL22620.1 EFL22633.1 EFL22633.1 EFL22758.1 EFL22758.1 EFL22980.1 EFL22980.1 EFL22997.1 EFL22997.1 gcvT gcvT gcvH gcvH glyA-2 glyA-2 EFL23055.1 EFL23055.1 EFL23072.1 EFL23072.1 EFL23126.1 EFL23126.1 EFL23128.1 EFL23128.1 pfkA-2 pfkA-2 EFL23140.1 EFL23140.1 ackA ackA EFL23142.1 EFL23142.1 EFL23152.1 EFL23152.1 EFL23165.1 EFL23165.1 EFL23166.1 EFL23166.1 EFL23180.1 EFL23180.1 EFL23200.1 EFL23200.1 EFL23201.1 EFL23201.1 EFL23224.1 EFL23224.1 EFL23228.1 EFL23228.1 glyA-3 glyA-3 EFL23292.1 EFL23292.1 EFL23310.1 EFL23310.1 EFL23345.1 EFL23345.1 EFL23354.1 EFL23354.1 EFL23373.1 EFL23373.1 EFL23473.1 EFL23473.1 EFL23495.1 EFL23495.1 EFL23496.1 EFL23496.1 EFL23502.1 EFL23502.1 EFL23520.1 EFL23520.1 EFL23526.1 EFL23526.1 EFL23529.1 EFL23529.1 fumC fumC EFL23572.1 EFL23572.1 EFL23610.1 EFL23610.1 prs prs ppc ppc EFL23762.1 EFL23762.1 EFL23960.1 EFL23960.1 EFL24096.1 EFL24096.1 EFL24103.1 EFL24103.1 EFL24122.1 EFL24122.1 EFL24123.1 EFL24123.1 EFL24141.1 EFL24141.1 EFL24209.1 EFL24209.1 EFL24402.1 EFL24402.1 EFL24444.1 EFL24444.1 EFL24468.1 EFL24468.1 EFL24475.1 EFL24475.1 EFL24476.1 EFL24476.1 EFL24517.1 EFL24517.1 EFL24612.1 EFL24612.1 EFL24613.1 EFL24613.1 EFL29383.1 EFL29383.1 EFL29353.1 EFL29353.1 EFL29205.1 EFL29205.1 EFL29170.1 EFL29170.1 EFL29098.1 EFL29098.1 EFL28919.1 EFL28919.1 EFL28917.1 EFL28917.1 EFL28909.1 EFL28909.1 EFL28908.1 EFL28908.1 EFL28905.1 EFL28905.1 EFL28888.1 EFL28888.1 EFL28854.1 EFL28854.1 EFL28853.1 EFL28853.1 EFL28852.1 EFL28852.1 EFL28839.1 EFL28839.1 EFL28838.1 EFL28838.1 EFL28837.1 EFL28837.1 EFL28826.1 EFL28826.1 EFL28811.1 EFL28811.1 EFL28772.1 EFL28772.1 EFL28749.1 EFL28749.1 EFL28746.1 EFL28746.1 EFL28745.1 EFL28745.1 EFL28661.1 EFL28661.1 EFL28551.1 EFL28551.1 EFL28512.1 EFL28512.1 EFL28510.1 EFL28510.1 EFL28486.1 EFL28486.1 EFL28380.1 EFL28380.1 EFL28373.1 EFL28373.1 EFL28371.1 EFL28371.1 EFL28351.1 EFL28351.1 EFL28326.1 EFL28326.1 EFL28280.1 EFL28280.1 EFL28277.1 EFL28277.1 EFL28275.1 EFL28275.1 EFL28213.1 EFL28213.1 EFL28209.1 EFL28209.1 EFL28186.1 EFL28186.1 EFL28183.1 EFL28183.1 EFL28072.1 EFL28072.1 EFL28057.1 EFL28057.1 EFL28027.1 EFL28027.1 EFL28013.1 EFL28013.1 EFL27990.1 EFL27990.1 EFL27958.1 EFL27958.1 EFL27935.1 EFL27935.1 EFL27876.1 EFL27876.1 EFL27857.1 EFL27857.1 EFL27818.1 EFL27818.1 EFL27781.1 EFL27781.1 EFL27606.1 EFL27606.1 EFL27600.1 EFL27600.1 EFL27599.1 EFL27599.1 EFL27583.1 EFL27583.1 EFL27582.1 EFL27582.1 vapC-3 vapC-3 EFL27461.1 EFL27461.1 EFL27460.1 EFL27460.1 EFL27416.1 EFL27416.1 EFL27415.1 EFL27415.1 EFL27358.1 EFL27358.1 EFL27335.1 EFL27335.1 EFL27311.1 EFL27311.1 EFL27308.1 EFL27308.1 EFL27307.1 EFL27307.1 EFL27304.1 EFL27304.1 EFL27278.1 EFL27278.1 EFL27277.1 EFL27277.1 EFL27187.1 EFL27187.1 EFL27060.1 EFL27060.1 EFL27045.1 EFL27045.1 EFL27009.1 EFL27009.1 tal tal zwf zwf EFL27005.1 EFL27005.1 EFL27004.1 EFL27004.1 tpiA tpiA pgk pgk EFL26999.1 EFL26999.1 EFL26956.1 EFL26956.1 EFL26947.1 EFL26947.1 EFL26912.1 EFL26912.1 EFL26910.1 EFL26910.1 EFL26841.1 EFL26841.1 pfp-2 pfp-2 EFL26809.1 EFL26809.1 EFL26766.1 EFL26766.1 EFL26765.1 EFL26765.1 EFL26763.1 EFL26763.1 EFL26642.1 EFL26642.1 EFL26605.1 EFL26605.1 EFL26596.1 EFL26596.1 EFL26549.1 EFL26549.1 EFL26469.1 EFL26469.1 EFL26424.1 EFL26424.1 EFL26246.1 EFL26246.1 EFL26161.1 EFL26161.1 EFL26118.1 EFL26118.1 EFL26094.1 EFL26094.1 EFL26056.1 EFL26056.1 EFL26055.1 EFL26055.1 EFL26054.1 EFL26054.1 EFL26011.1 EFL26011.1 EFL26008.1 EFL26008.1 EFL25995.1 EFL25995.1 EFL25927.1 EFL25927.1 EFL25926.1 EFL25926.1 EFL25833.1 EFL25833.1 EFL25762.1 EFL25762.1 EFL25675.1 EFL25675.1 EFL25609.1 EFL25609.1 EFL25554.1 EFL25554.1 EFL25529.1 EFL25529.1 eno eno EFL25490.1 EFL25490.1 EFL25485.1 EFL25485.1 EFL25386.1 EFL25386.1 EFL25357.1 EFL25357.1 EFL25350.1 EFL25350.1 EFL25349.1 EFL25349.1 EFL25348.1 EFL25348.1 EFL25347.1 EFL25347.1 mdh mdh folD folD sucD sucD sucC sucC vapC-2 vapC-2 EFL25238.1 EFL25238.1 EFL25233.1 EFL25233.1 serC serC EFL25181.1 EFL25181.1 EFL25170.1 EFL25170.1 EFL25169.1 EFL25169.1 EFL25160.1 EFL25160.1 gpmA gpmA EFL25106.1 EFL25106.1 EFL24963.1 EFL24963.1 EFL24947.1 EFL24947.1 acsA acsA pfp pfp EFL24719.1 EFL24719.1 EFL24673.1 EFL24673.1 EFL24631.1 EFL24631.1 EFL24628.1 EFL24628.1 EFL24627.1 EFL24627.1 EFL24614.1 EFL24614.1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
EFL24626.1Pyruvate dehydrogenase E2 (dihydrolipoamide acetyltransferase). (464 aa)
EFL20313.1Putative LigA. (437 aa)
EFL20381.1NAD-dependent malic enzyme. (470 aa)
EFL20395.1L-serine ammonia-lyase; Belongs to the iron-sulfur dependent L-serine dehydratase family. (460 aa)
EFL20399.1Mycothiol-dependent formaldehyde dehydrogenase. (361 aa)
EFL20404.1Methylenetetrahydrofolate dehydrogenase/methenyltetrahydrofolate cyclohydrolase. (79 aa)
EFL20405.1Methylenetetrahydrofolate dehydrogenase/methenyltetrahydrofolate cyclohydrolase. (175 aa)
glyAGlycine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. (409 aa)
EFL20479.1ROK family transcriptional regulator. (432 aa)
EFL20655.1Fructose-1,6-bisphosphate aldolase, class II. (280 aa)
EFL20687.1Transketolase. (620 aa)
EFL20691.1Conserved hypothetical protein; Truncated CDS. (204 aa)
EFL20710.1methylmalonyl-CoA mutase, alpha subunit. (741 aa)
EFL20712.1methylmalonyl-CoA mutase, beta subunit. (525 aa)
EFL20762.1crotonyl-CoA reductase. (447 aa)
EFL20795.1Modular polyketide synthase. (582 aa)
EFL20798.1Modular polyketide synthase; Unextendable partial coding region. (350 aa)
EFL20814.1Modular polyketide synthase. (488 aa)
EFL20920.1GntR family transcriptional regulator. (270 aa)
EFL21007.1Putative 2-hydroxyacid-family dehydrogenase; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (348 aa)
pfkA6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis; Belongs to the phosphofructokinase type A (PFKA) family. Mixed-substrate PFK group III subfamily. (341 aa)
EFL21069.1LigA protein. (604 aa)
EFL21130.1Putative ROK-family transcriptional regulator. (396 aa)
EFL21131.1Putative GntR-family transcriptional regulator. (251 aa)
EFL21189.1AMP-binding protein. (146 aa)
EFL21238.1Thiolase; Belongs to the thiolase-like superfamily. Thiolase family. (382 aa)
icmFB12 binding domain/ArgK/methylmalonyl-CoA mutase; Catalyzes the reversible interconversion of isobutyryl-CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly. (1083 aa)
EFL21243.13-hydroxybutyryl-CoA dehydrogenase. (285 aa)
EFL21255.1Probable 3-hydroxyacyl-CoA dehydrogenase protein. (190 aa)
EFL21263.1Pyruvate dehydrogenase E1 component; Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). (789 aa)
EFL21280.1LigA protein. (480 aa)
EFL21298.1ATP-grasp domain protein. (418 aa)
EFL21312.1NAD-dependent malic enzyme. (481 aa)
EFL21377.1Glycine dehydrogenase; Truncated CDS; Belongs to the GcvP family. (860 aa)
EFL21417.1Mycothiol-dependent formaldehyde dehydrogenase. (361 aa)
EFL21454.1Nonspecific lipid-transfer protein. (388 aa)
EFL21501.1Pyridoxal-phosphate dependent enzyme. (377 aa)
EFL21508.1Putative ROK family regulatory protein. (408 aa)
EFL21526.1Putative glucokinase. (284 aa)
EFL21605.1Secreted protein. (347 aa)
EFL21701.1Putative ROK-family transcriptional regulator. (415 aa)
EFL21717.1Putative transcriptional repressor. (389 aa)
EFL21744.1Conserved hypothetical protein. (126 aa)
EFL21784.1Ribulose-phosphate 3-epimerase; Belongs to the ribulose-phosphate 3-epimerase family. (230 aa)
EFL21786.1Isocitrate dehydrogenase, NADP-dependent; Belongs to the monomeric-type IDH family. (739 aa)
EFL21944.1Conserved hypothetical protein. (413 aa)
EFL21995.13-hydroxyacyl-CoA dehydrogenase. (286 aa)
EFL22081.1Fatty oxidation complex, alpha subunit. (730 aa)
EFL22104.1GntR family transcriptional regulator. (242 aa)
EFL22158.1ROK family transcriptional regulator. (418 aa)
EFL22209.1Putative ROK-family transcriptional regulator. (49 aa)
EFL22210.1Putative ROK-family transcriptional regulator. (249 aa)
EFL22254.1Putative LigA. (510 aa)
EFL22321.1Catalase HPII. (607 aa)
EFL22342.13-hydroxybutyryl-CoA dehydrogenase. (611 aa)
EFL22346.1crotonyl-CoA reductase. (445 aa)
EFL22347.1methylmalonyl-CoA mutase. (672 aa)
EFL22377.1Transketolase, N- subunit. (293 aa)
EFL22378.1Transketolase, C- subunit. (323 aa)
EFL22389.1ROK family transcriptional regulator. (421 aa)
EFL22414.1Glucokinase. (384 aa)
EFL22418.1GntR family transcriptional regulator. (239 aa)
EFL22433.12-dehydro-3-deoxyphosphogluconate aldolase/4-hydroxy-2-oxoglutarate aldolase. (217 aa)
EFL22434.12-dehydro-3-deoxygluconokinase. (321 aa)
EFL22456.1Malate synthase A; Belongs to the malate synthase family. (539 aa)
EFL22469.1Putative acetyl-CoA synthetase. (383 aa)
EFL22493.1Mercuric reductase/transcriptional regulator, fusion. (479 aa)
EFL22575.1Dihydrolipoyl dehydrogenase. (470 aa)
EFL22612.1Fatty acid oxidation complex alpha-subunit. (709 aa)
EFL22620.1ROK family transcriptional regulator. (401 aa)
EFL22633.1Aconitate hydratase 1; Catalyzes the isomerization of citrate to isocitrate via cis- aconitate. (910 aa)
EFL22758.1Putative phosphoglycerate mutase family protein; Unextendable partial coding region. (212 aa)
EFL22980.1methylmalonyl-CoA decarboxylase, alpha subunit. (527 aa)
EFL22997.1Phosphoglycerate dehydrogenase; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (533 aa)
gcvTGlycine cleavage system T protein; The glycine cleavage system catalyzes the degradation of glycine. (375 aa)
gcvHGlycine cleavage system H protein; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein. (126 aa)
glyA-2Glycine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. (421 aa)
EFL23055.1L-serine ammonia-lyase; Belongs to the iron-sulfur dependent L-serine dehydratase family. (437 aa)
EFL23072.1enoyl-CoA hydratase; Belongs to the enoyl-CoA hydratase/isomerase family. (255 aa)
EFL23126.12-keto-3-deoxygluconate kinase. (325 aa)
EFL23128.12-dehydro-3-deoxyphosphogluconate aldolase/4-hydroxy-2-oxoglutarate aldolase. (213 aa)
pfkA-26-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis; Belongs to the phosphofructokinase type A (PFKA) family. Mixed-substrate PFK group III subfamily. (341 aa)
EFL23140.1Phosphate acetyltransferase; Involved in acetate metabolism. In the N-terminal section; belongs to the CobB/CobQ family. (698 aa)
ackAAcetate kinase; Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction; Belongs to the acetokinase family. (381 aa)
EFL23142.1Pyruvate kinase; Belongs to the pyruvate kinase family. (475 aa)
EFL23152.1Putative methylmalonyl-CoA mutase. (566 aa)
EFL23165.1acetyl-CoA acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family. (399 aa)
EFL23166.1methylmalonyl-CoA epimerase. (146 aa)
EFL23180.1Putative 3-hydroxyacyl-CoA dehydrogenase. (282 aa)
EFL23200.1Methylaspartate mutase subunit E (MutE) superfamily protein. (431 aa)
EFL23201.1Putative B12 binding domain protein. (163 aa)
EFL23224.1Modular polyketide synthase; Unextendable partial coding region. (1024 aa)
EFL23228.1Modular polyketide synthase. (2029 aa)
glyA-3Glycine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. (423 aa)
EFL23292.1Oxoglutarate dehydrogenase (succinyl-transferring), E1 component. (1278 aa)
EFL23310.1Malate dehydrogenase (oxaloacetate-decarboxylating). (410 aa)
EFL23345.1Transcriptional regulator, GntR-family. (257 aa)
EFL23354.1Phosphoglycerate mutase. (256 aa)
EFL23373.1Catalase; Belongs to the catalase family. (488 aa)
EFL23473.1Glyceraldehyde-3-phosphate dehydrogenase, type I; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family. (332 aa)
EFL23495.1Putative FAD flavoprotein oxidase. (661 aa)
EFL23496.1Ferredoxin, 2Fe-2S. (256 aa)
EFL23502.1Regulatory protein GntR, HTH. (250 aa)
EFL23520.1Polyphosphate-glucose phosphotransferase. (262 aa)
EFL23526.1Fructose-1,6-bisphosphatase, class II. (343 aa)
EFL23529.1Fumarate hydratase, class I; Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family. (547 aa)
fumCFumarate hydratase, class II; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily. (463 aa)
EFL23572.12-keto-3-deoxygluconate kinase. (368 aa)
EFL23610.1Threonine ammonia-lyase. (424 aa)
prsRibose-phosphate pyrophosphokinase; Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib- 5-P); Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily. (325 aa)
ppcPhosphoenolpyruvate carboxykinase (GTP); Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle; Belongs to the PEPCase type 1 family. (906 aa)
EFL23762.1acetate-CoA ligase. (168 aa)
EFL23960.1Alcohol dehydrogenase class III. (350 aa)
EFL24096.1MaoC family protein. (144 aa)
EFL24103.1Putative transcriptional regulator, GntR family. (261 aa)
EFL24122.1Ferredoxin oxidoreductase, alpha subunit. (649 aa)
EFL24123.1Putative oxidoreductase. (360 aa)
EFL24141.1Putative oxidoreductase. (913 aa)
EFL24209.1ROK family transcriptional regulator. (277 aa)
EFL24402.1Conserved domain protein. (68 aa)
EFL24444.1Fructose-bisphosphate aldolase, class II; Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis; Belongs to the class II fructose-bisphosphate aldolase family. (340 aa)
EFL24468.1Ferredoxin, 4Fe-4S. (754 aa)
EFL24475.1Putative regulatory protein KorSA, GntR-family transcriptional regulator. (259 aa)
EFL24476.1Putative GntR-family regulatory protein. (180 aa)
EFL24517.1ATP/GTP binding protein. (179 aa)
EFL24612.1Pyruvate dehydrogenase E2 (dihydrolipoamide acetyltransferase); Truncated CDS. (349 aa)
EFL24613.1Pyruvate dehydrogenase E1 component, beta subunit. (326 aa)
EFL29383.1Putative GntR-family transcriptional regulatory protein. (266 aa)
EFL29353.1ATP/GTP binding protein; Truncated CDS. (69 aa)
EFL29205.1Putative secreted protein. (536 aa)
EFL29170.1NagC-related protein. (408 aa)
EFL29098.1Putative enoyl-CoA hydratase/isomerase family protein; Belongs to the enoyl-CoA hydratase/isomerase family. (262 aa)
EFL28919.1Putative Crp-family transcriptional regulator. (380 aa)
EFL28917.1Putative oxidoreductase. (320 aa)
EFL28909.1Putative transketolase subunit B. (341 aa)
EFL28908.1Putative transketolase subunit A. (276 aa)
EFL28905.1Ribose 5-phosphate isomerase. (158 aa)
EFL28888.1Dihydrolipoyl dehydrogenase. (469 aa)
EFL28854.1Formate dehydrogenase, major subunit; Unextendable partial coding region. (188 aa)
EFL28853.1Formate dehydrogenase-O, major subunit; Unextendable partial coding region. (884 aa)
EFL28852.1Formate dehydrogenase, iron-sulfur subunit; Unextendable partial coding region. (260 aa)
EFL28839.1Pyruvate dehydrogenase E2 (dihydrolipoamide acetyltransferase). (450 aa)
EFL28838.1Pyruvate dehydrogenase E1 component, beta subunit. (346 aa)
EFL28837.1Pyruvate dehydrogenase E1 component, alpha subunit. (361 aa)
EFL28826.1Aldehyde dehydrogenase. (482 aa)
EFL28811.1Putative kinase; Truncated CDS. (134 aa)
EFL28772.16-phosphogluconate dehydrogenase, decarboxylating; Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH. (484 aa)
EFL28749.1Putative 4-phosphoerythronate dehydrogenase; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (330 aa)
EFL28746.1Putative arsenate reductase; Belongs to the ArsC family. (122 aa)
EFL28745.1acyl-CoA ligase; Truncated CDS. (458 aa)
EFL28661.1Vegetative cell wall protein gp1 (Hydroxyproline-rich glycoprotein 1); Unextendable partial coding region. (433 aa)
EFL28551.1Pyridoxal-phosphate dependent enzyme. (314 aa)
EFL28512.1Pyruvate carboxylase; Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second. (1125 aa)
EFL28510.1Phosphoglycerate dehydrogenase; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (332 aa)
EFL28486.1Malate oxidoreductase. (586 aa)
EFL28380.1Conserved hypothetical protein. (138 aa)
EFL28373.1Methylenetetrahydromethanopterin reductase. (312 aa)
EFL28371.1ROK family transcriptional regulator. (425 aa)
EFL28351.1Putative 2-hydroxyacid-family dehydrogenase. (337 aa)
EFL28326.1D-3-phosphoglycerate dehydrogenase; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (332 aa)
EFL28280.1LigA protein. (360 aa)
EFL28277.1Aconitate hydratase 1. (712 aa)
EFL28275.1Putative aconitate hydratase. (656 aa)
EFL28213.1HAD-superfamily subfamily IB hydrolase. (241 aa)
EFL28209.1Glyceraldehyde-3-phosphate dehydrogenase, type I; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family. (484 aa)
EFL28186.1Ribose 5-phosphate isomerase. (154 aa)
EFL28183.1Putative D-3-phosphoglycerate dehydrogenase; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (356 aa)
EFL28072.1Putative SIS domain protein. (300 aa)
EFL28057.1Conserved hypothetical protein. (197 aa)
EFL28027.1Putative acyl-CoA oxidase. (604 aa)
EFL28013.1Transcriptional regulator, GntR family/UbiC transcription regulator. (238 aa)
EFL27990.1Strictosidine synthase. (325 aa)
EFL27958.1Methylenetetrahydrofolate reductase (NAD(P)H); Belongs to the methylenetetrahydrofolate reductase family. (326 aa)
EFL27935.1GntR family transcriptional regulator. (260 aa)
EFL27876.1D-3-phosphoglycerate dehydrogenase; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (340 aa)
EFL27857.1Modular polyketide synthase; Overlaps another CDS with the same product name; unextendable partial coding region. (1187 aa)
EFL27818.1D-3-phosphoglycerate dehydrogenase; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (317 aa)
EFL27781.1LigA protein. (672 aa)
EFL27606.1Phosphoglycerate dehydrogenase; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (529 aa)
EFL27600.1Modular polyketide synthase. (1078 aa)
EFL27599.1Modular polyketide synthase; Truncated CDS. (1307 aa)
EFL27583.1Hypothetical protein. (111 aa)
EFL27582.1Putative 2-dehydro-3-deoxyphosphogluconate aldolase/4-hydroxy-2-oxoglutarate aldolase; Truncated CDS; unextendable partial coding region. (110 aa)
vapC-3PIN family toxin-antitoxin system, toxin component; Toxic component of a toxin-antitoxin (TA) system. An RNase. Belongs to the PINc/VapC protein family. (140 aa)
EFL27461.12-dehydro-3-deoxyphosphogluconate aldolase/4-hydroxy-2-oxoglutarate aldolase. (213 aa)
EFL27460.1Putative transcriptional regulator. (221 aa)
EFL27416.1Ferredoxin Fas2. (235 aa)
EFL27415.1Putative transketolase; Truncated CDS. (271 aa)
EFL27358.1Phosphoglycerate mutase. (204 aa)
EFL27335.1Putative Formate dehydrogenase. (209 aa)
EFL27311.1Mycothiol-dependent formaldehyde dehydrogenase. (302 aa)
EFL27308.1Oxidoreductase, molybdopterin-binding. (237 aa)
EFL27307.1Oxidoreductase, molybdopterin-binding. (424 aa)
EFL27304.1Putative GntR-family transcriptional regulator; Unextendable partial coding region. (250 aa)
EFL27278.1Putative siderophore biosynthesis protein. (380 aa)
EFL27277.1acetyl-CoA carboxylase, carboxyl transferase, beta subunit; Truncated CDS. (338 aa)
EFL27187.1Phosphoserine phosphatase. (411 aa)
EFL27060.1Putative threonine dehydratase, PLP-dependent. (325 aa)
EFL27045.1Glutathione-independent formaldehyde dehydrogenase. (392 aa)
EFL27009.1Transketolase; Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate. (692 aa)
talTransaldolase; Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway; Belongs to the transaldolase family. Type 2 subfamily. (372 aa)
zwfGlucose-6-phosphate dehydrogenase; Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone. (511 aa)
EFL27005.16-phosphogluconolactonase. (172 aa)
EFL27004.1Glucose-6-phosphate isomerase; Belongs to the GPI family. (281 aa)
tpiATriose-phosphate isomerase; Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P); Belongs to the triosephosphate isomerase family. (258 aa)
pgkPhosphoglycerate kinase; Belongs to the phosphoglycerate kinase family. (400 aa)
EFL26999.1Glyceraldehyde-3-phosphate dehydrogenase, type I; Unextendable partial coding region; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family. (191 aa)
EFL26956.1Oxidoreductase alpha (molybdopterin) subunit. (762 aa)
EFL26947.1Pyruvate kinase; Belongs to the pyruvate kinase family. (476 aa)
EFL26912.1Conserved hypothetical protein. (154 aa)
EFL26910.1Putative regulatory protein KorSA, GntR-family transcriptional regulator. (254 aa)
EFL26841.1Methylenetetrahydrofolate reductase (NAD(P)H); Belongs to the methylenetetrahydrofolate reductase family. (305 aa)
pfp-26-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP- PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions. (342 aa)
EFL26809.1Glucokinase. (313 aa)
EFL26766.1Dihydrolipoyl dehydrogenase. (468 aa)
EFL26765.1Dihydrolipoyllysine-residue succinyltransferase, E2 component of oxoglutarate dehydrogenase (succinyl-transferring) complex. (304 aa)
EFL26763.1Pyruvate dehydrogenase (acetyl-transferring), homodimeric type; Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). (891 aa)
EFL26642.1Ferrous iron permease EfeU. (323 aa)
EFL26605.12-dehydro-3-deoxyphosphogluconate aldolase/4-hydroxy-2-oxoglutarate aldolase; Unextendable partial coding region. (210 aa)
EFL26596.1Putative zinc-binding dehydrogenase. (361 aa)
EFL26549.1Thiolase; Belongs to the thiolase-like superfamily. Thiolase family. (389 aa)
EFL26469.1Pyruvate dehydrogenase (acetyl-transferring), homodimeric type; Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). (909 aa)
EFL26424.1Putative transcriptional regulator, GntR family. (239 aa)
EFL26246.1Pyruvate, phosphate dikinase; Belongs to the PEP-utilizing enzyme family. (908 aa)
EFL26161.1Phosphoglycerate mutase; Belongs to the phosphoglycerate mutase family. (217 aa)
EFL26118.1Ribose 5-phosphate isomerase. (162 aa)
EFL26094.1Putative ROK-family transcriptional regulatory protein. (414 aa)
EFL26056.1Succinate dehydrogenase subunit. (248 aa)
EFL26055.1Fumarate reductase, flavoprotein subunit. (648 aa)
EFL26054.1Fumarate reductase, iron-sulfur protein. (252 aa)
EFL26011.1Methylmalonate-semialdehyde dehydrogenase (acylating). (498 aa)
EFL26008.1Deoxyribose-phosphate aldolase. (292 aa)
EFL25995.1Citrate (Si)-synthase; Belongs to the citrate synthase family. (430 aa)
EFL25927.1acetyl/propionyl-CoA carboxylase, alpha subunit; Unextendable partial coding region. (528 aa)
EFL25926.1acetyl/propionyl-CoA carboxylase, alpha subunit. (151 aa)
EFL25833.1acetyl-CoA carboxylase subunit alpha. (584 aa)
EFL25762.1Putative ROK-family transcriptional regulator. (367 aa)
EFL25675.1NAD-dependent malic enzyme. (473 aa)
EFL25609.1Conserved hypothetical protein. (447 aa)
EFL25554.1Transcriptional regulator. (294 aa)
EFL25529.1acetyl-CoA acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family. (406 aa)
enoPhosphopyruvate hydratase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family. (426 aa)
EFL25490.1propionyl-CoA carboxylase, beta subunit. (531 aa)
EFL25485.1acetyl-CoA carboxylase subunit alpha. (584 aa)
EFL25386.1Shikimate kinase. (171 aa)
EFL25357.1Putative methylmalonyl-CoA mutase. (527 aa)
EFL25350.1Succinate dehydrogenase, cytochrome b556 subunit. (126 aa)
EFL25349.1Succinate dehydrogenase, hydrophobic membrane anchor protein. (159 aa)
EFL25348.1Succinate dehydrogenase, flavoprotein subunit. (584 aa)
EFL25347.1Succinate dehydrogenase, iron-sulfur subunit; Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family. (257 aa)
mdhMalate dehydrogenase; Catalyzes the reversible oxidation of malate to oxaloacetate. Belongs to the LDH/MDH superfamily. MDH type 2 family. (329 aa)
folDMethylenetetrahydrofolate dehydrogenase/methenyltetrahydrofolate cyclohydrolase; Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate. (295 aa)
sucDsuccinyl-CoA synthetase, alpha subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit. (294 aa)
sucCsuccinyl-CoA synthetase, beta subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. (390 aa)
vapC-2PIN family toxin-antitoxin system, toxin component; Toxic component of a toxin-antitoxin (TA) system. An RNase. Belongs to the PINc/VapC protein family. (138 aa)
EFL25238.1Citrate (Si)-synthase; Belongs to the citrate synthase family. (371 aa)
EFL25233.1acetyl/propionyl-CoA carboxylase, alpha subunit. (651 aa)
serCPutative phosphoserine aminotransferase; Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine; Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily. (372 aa)
EFL25181.1Putative RpiR-family transcriptional regulator. (310 aa)
EFL25170.1Glucokinase; Unextendable partial coding region. (170 aa)
EFL25169.1Putative sugar kinase. (87 aa)
EFL25160.1Mycothiol-dependent formaldehyde dehydrogenase. (360 aa)
gpmAPhosphoglycerate mutase; Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate. (253 aa)
EFL25106.1Putative ROK-family transcriptional regulator. (323 aa)
EFL24963.1Zinc-binding dehydrogenase. (369 aa)
EFL24947.1HAD-superfamily subfamily IB hydrolase. (278 aa)
acsAacetate-CoA ligase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family. (653 aa)
pfp6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP- PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions. (341 aa)
EFL24719.1Conserved hypothetical protein. (217 aa)
EFL24673.16-phosphogluconate dehydrogenase (decarboxylating). (292 aa)
EFL24631.13-hydroxyacyl-CoA dehydrogenase PaaC. (513 aa)
EFL24628.1Putative 2-oxoisovalerate dehydrogenase E1 component, alpha subunit; Unextendable partial coding region. (375 aa)
EFL24627.1Pyruvate dehydrogenase E1 component, beta subunit; Unextendable partial coding region. (338 aa)
EFL24614.1Pyruvate dehydrogenase (acetyl-transferring) E1 component, alpha subunit. (387 aa)
Your Current Organism:
Streptomyces himastatinicus
NCBI taxonomy Id: 457427
Other names: S. himastatinicus ATCC 53653, Streptomyces himastatinicus ATCC 53653, Streptomyces himastatinicus str. ATCC 53653, Streptomyces himastatinicus strain ATCC 53653, Streptomyces hygroscopicus ATCC 53653
Server load: low (18%) [HD]