(61 nodes) Mixed, incl. Pentose phosphate pathway, and Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein network (Trichinella britovi)

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	Rpe	Ribulose-phosphate 3-epimerase. (234 aa)
	pgk-1	Phosphoglycerate kinase. (568 aa)
	enol-1	Enolase. (459 aa)
	Dera	Putative deoxyribose-phosphate aldolase. (357 aa)
	gmppb	Mannose-1-phosphate guanyltransferase beta. (359 aa)
	add-1	Adducin-related protein 1. (778 aa)
	GlyP	Alpha-1,4 glucan phosphorylase; Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties. (1509 aa)
	tps-2	Alpha,alpha-trehalose-phosphate synthase [UDP-forming] 2. (1450 aa)
	Gclm	Cytidine deaminase. (687 aa)
	TSTA3	GDP-L-fucose synthase. (553 aa)
	ALG2	Alpha-1,3/1,6-mannosyltransferase ALG2. (390 aa)
	Fbp2	Fructose-1,6-bisphosphatase isozyme 2; Belongs to the FBPase class 1 family. (341 aa)
	Tktl2	Transketolase-like protein 2. (1276 aa)
	PGM2	Phosphoglucomutase-2. (606 aa)
	MVK	2,3-bisphosphoglycerate-independent phosphoglycerate mutase. (524 aa)
	PFK	ATP-dependent 6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis; Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Eukaryotic two domain clade 'E' sub-subfamily. (910 aa)
	Tal	Transaldolase; Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway. (398 aa)
	PFK-2	ATP-dependent 6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis; Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Eukaryotic two domain clade 'E' sub-subfamily. (846 aa)
	GPI	Glucose-6-phosphate isomerase; Belongs to the GPI family. (601 aa)
	XYLB	Xylulose kinase. (531 aa)
	ndx-2	Putative nudix hydrolase 2; Belongs to the Nudix hydrolase family. (237 aa)
	UAP1	UDP-N-acetylhexosamine pyrophosphorylase. (742 aa)
	idnk	Gluconokinase; Belongs to the gluconokinase GntK/GntV family. (188 aa)
	ALG2-2	Alpha-1,3/1,6-mannosyltransferase ALG2. (708 aa)
	tpi-1	Triosephosphate isomerase. (278 aa)
	ALG2-3	Alpha-1,3/1,6-mannosyltransferase ALG2. (708 aa)
	Gmd	GDP-mannose 4,6 dehydratase. (456 aa)
	AGL	Glycogen debranching enzyme. (1742 aa)
	RPIA	Ribose-5-phosphate isomerase. (366 aa)
	aldo-1	Fructose-bisphosphate aldolase; Belongs to the class I fructose-bisphosphate aldolase family. (408 aa)
	T03_6366	Putative glucosamine 6-phosphate N-acetyltransferase. (491 aa)
	gmppa-b	Mannose-1-phosphate guanyltransferase alpha-B. (454 aa)
	T03_16395	Phosphotransferase. (470 aa)
	T25B9.9	6-phosphogluconate dehydrogenase, decarboxylating; Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH. (489 aa)
	prps2	Ribose-phosphate pyrophosphokinase 2. (318 aa)
	gspd-1	Glucose-6-phosphate 1-dehydrogenase; Catalyzes the rate-limiting step of the oxidative pentose- phosphate pathway, which represents a route for the dissimilation of carbohydrates besides glycolysis. (537 aa)
	Mpi	Mannose-6-phosphate isomerase. (423 aa)
	GBE1	1,4-alpha-glucan-branching enzyme. (1408 aa)
	sgl	UDP-glucose 6-dehydrogenase. (574 aa)
	TREH	Trehalase. (614 aa)
	Pgm3	Phosphoacetylglucosamine mutase. (893 aa)
	RBKS	Ribokinase. (338 aa)
	rpia-1	Probable-ribose 5-phosphate isomerase. (249 aa)
	ppp1r3c	Protein phosphatase 1 regulatory subunit 3C. (232 aa)
	AMDHD2	N-acetylglucosamine-6-phosphate deacetylase; Belongs to the metallo-dependent hydrolases superfamily. NagA family. (407 aa)
	PPP1R3B	Protein phosphatase 1 regulatory subunit 3B. (351 aa)
	T03_1092	Phosphotransferase. (516 aa)
	PKM	Pyruvate kinase; Belongs to the pyruvate kinase family. (626 aa)
	ppp1r3cb	Protein phosphatase 1 regulatory subunit 3C-B. (453 aa)
	Galk2-2	N-acetylgalactosamine kinase. (474 aa)
	PGM1	Phosphoglucomutase-1; Belongs to the phosphohexose mutase family. (565 aa)
	PRPSAP2	Phosphoribosyl pyrophosphate synthase-associated protein 2. (772 aa)
	UXS1	UDP-glucuronic acid decarboxylase 1. (710 aa)
	Gale	UDP-glucose 4-epimerase; Belongs to the amiloride-sensitive sodium channel (TC 1.A.6) family. (788 aa)
	gsy-1	Glycogen [starch] synthase; Transfers the glycosyl residue from UDP-Glc to the non- reducing end of alpha-1,4-glucan. (685 aa)
	Gnpda1	Glucosamine-6-phosphate isomerase. (332 aa)
	Gfpt1	Glutamine--fructose-6-phosphate aminotransferase [isomerizing] 1. (697 aa)
	PFK-3	6-phosphofructokinase. (771 aa)
	Nagk	N-acetyl-D-glucosamine kinase. (420 aa)
	gpd-1	Glyceraldehyde-3-phosphate dehydrogenase. (346 aa)
	Gyg1	Glycogenin-1. (404 aa)

Your Current Organism:

Trichinella britovi

NCBI taxonomy Id: 45882
Other names: T. britovi

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AGL	ALG2	A0A0V1CT18	A0A0V1CEL9	Glycogen debranching enzyme.	Alpha-1,3/1,6-mannosyltransferase ALG2.	0.760
AGL	ALG2-2	A0A0V1CT18	A0A0V1CPV2	Glycogen debranching enzyme.	Alpha-1,3/1,6-mannosyltransferase ALG2.	0.760
AGL	ALG2-3	A0A0V1CT18	A0A0V1CR30	Glycogen debranching enzyme.	Alpha-1,3/1,6-mannosyltransferase ALG2.	0.760
AGL	GBE1	A0A0V1CT18	A0A0V1D0V2	Glycogen debranching enzyme.	1,4-alpha-glucan-branching enzyme.	0.966
AGL	GPI	A0A0V1CT18	A0A0V1CMH1	Glycogen debranching enzyme.	Glucose-6-phosphate isomerase; Belongs to the GPI family.	0.550
AGL	GlyP	A0A0V1CT18	A0A0V1CD08	Glycogen debranching enzyme.	Alpha-1,4 glucan phosphorylase; Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties.	0.991
AGL	Gyg1	A0A0V1CT18	A0A0V1DHW1	Glycogen debranching enzyme.	Glycogenin-1.	0.992
AGL	PGM1	A0A0V1CT18	A0A0V1DC61	Glycogen debranching enzyme.	Phosphoglucomutase-1; Belongs to the phosphohexose mutase family.	0.971
AGL	PGM2	A0A0V1CT18	A0A0V1CGC2	Glycogen debranching enzyme.	Phosphoglucomutase-2.	0.874
AGL	PKM	A0A0V1CT18	A0A0V1D916	Glycogen debranching enzyme.	Pyruvate kinase; Belongs to the pyruvate kinase family.	0.754
AGL	Pgm3	A0A0V1CT18	A0A0V1D3C8	Glycogen debranching enzyme.	Phosphoacetylglucosamine mutase.	0.683
AGL	RBKS	A0A0V1CT18	A0A0V1D3D2	Glycogen debranching enzyme.	Ribokinase.	0.801
AGL	T03_1092	A0A0V1CT18	A0A0V1D7E3	Glycogen debranching enzyme.	Phosphotransferase.	0.570
AGL	T03_16395	A0A0V1CT18	A0A0V1CXP6	Glycogen debranching enzyme.	Phosphotransferase.	0.613
AGL	T25B9.9	A0A0V1CT18	A0A0V1CY70	Glycogen debranching enzyme.	6-phosphogluconate dehydrogenase, decarboxylating; Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH.	0.462
AGL	TREH	A0A0V1CT18	A0A0V1D2D4	Glycogen debranching enzyme.	Trehalase.	0.478
AGL	UAP1	A0A0V1CT18	A0A0V1CNB3	Glycogen debranching enzyme.	UDP-N-acetylhexosamine pyrophosphorylase.	0.886
AGL	gsy-1	A0A0V1CT18	A0A0V1DDJ9	Glycogen debranching enzyme.	Glycogen [starch] synthase; Transfers the glycosyl residue from UDP-Glc to the non- reducing end of alpha-1,4-glucan.	0.909
AGL	ndx-2	A0A0V1CT18	A0A0V1CMM1	Glycogen debranching enzyme.	Putative nudix hydrolase 2; Belongs to the Nudix hydrolase family.	0.796
AGL	tps-2	A0A0V1CT18	A0A0V1CD49	Glycogen debranching enzyme.	Alpha,alpha-trehalose-phosphate synthase [UDP-forming] 2.	0.768