(60 nodes) Perinuclear region of cytoplasm network (Trichinella britovi)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	ife-3	Eukaryotic translation initiation factor 4E-3; Belongs to the eukaryotic initiation factor 4E family. (219 aa)
	OSBP2	Oxysterol-binding protein; Belongs to the OSBP family. (776 aa)
	ALG2-3	Alpha-1,3/1,6-mannosyltransferase ALG2. (708 aa)
	usp20	Ubiquitin carboxyl-terminal hydrolase 20; Belongs to the peptidase C19 family. (731 aa)
	Cyld	Ubiquitin carboxyl-terminal hydrolase CYLD. (588 aa)
	ALG2-2	Alpha-1,3/1,6-mannosyltransferase ALG2. (708 aa)
	Ogt	UDP-N-acetylglucosamine-peptide N-acetylglucosaminyltransferase. (1026 aa)
	S	Protein Star. (318 aa)
	Rab4b	Ras-related protein Rab-4B. (574 aa)
	syd	JNK-interacting protein. (1281 aa)
	Mob4	MOB-like protein phocein. (280 aa)
	T03_17586	Four-domain proteases inhibitor. (302 aa)
	OSBPL6	Oxysterol-binding protein; Belongs to the OSBP family. (737 aa)
	T03_1933	Uncharacterized protein. (153 aa)
	Tsc2	Tuberin. (1672 aa)
	Nsfl1c	NSFL1 cofactor p47. (843 aa)
	asun	Protein asunder-like protein. (728 aa)
	GRASP	General receptor for phosphoinositides 1-associated scaffold protein. (351 aa)
	Eif4h	Eukaryotic translation initiation factor 4H. (206 aa)
	Cherp	Calcium homeostasis endoplasmic reticulum protein. (593 aa)
	ALG2	Alpha-1,3/1,6-mannosyltransferase ALG2. (390 aa)
	Mgat1-2	Alpha-1,3-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase. (559 aa)
	Mgat1	Alpha-1,3-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase. (621 aa)
	VPS53	Vacuolar protein sorting-associated protein 53-like protein. (802 aa)
	RAD51C	DNA repair protein RAD51-like protein 3. (1279 aa)
	pde-4	Putative 3',5'-cyclic phosphodiesterase pde-4. (130 aa)
	EHD1	EH domain-containing protein 1. (569 aa)
	Dgkq	Diacylglycerol kinase. (1323 aa)
	PAX9-2	Putative RING finger protein-like protein. (1082 aa)
	Trpv4	Transient receptor potential cation channel subfamily V member 4; Belongs to the transient receptor (TC 1.A.4) family. (1069 aa)
	cni	Protein cornichon. (143 aa)
	cav1	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (149 aa)
	pde-4-2	Phosphodiesterase. (811 aa)
	EHD1-2	EH domain-containing protein 1; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (588 aa)
	SIRT1	NAD-dependent protein deacetylase sirtuin-1. (432 aa)
	Ehd1	EH domain-containing protein 1. (758 aa)
	Aggf1	Angiogenic factor with G patch and FHA domains 1. (1194 aa)
	ATP7A	Copper-transporting ATPase 1. (1435 aa)
	cav-1	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (232 aa)
	Pde2a	Phosphodiesterase. (805 aa)
	pdhk-2	Protein-serine/threonine kinase. (456 aa)
	CANX	Calnexin. (579 aa)
	Actbeta	Inhibin beta chain. (423 aa)
	Dctn3	Dynactin subunit 3. (191 aa)
	DERL1	Derlin; May be involved in the degradation of misfolded endoplasmic reticulum (ER) luminal proteins; Belongs to the derlin family. (269 aa)
	Tsc1	Hamartin. (1160 aa)
	VPS52	Vacuolar protein sorting-associated protein 52-like protein. (1075 aa)
	PSEN1	Presenilin; Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors. Belongs to the peptidase A22A family. (496 aa)
	tyr-3-2	Putative tyrosinase-like protein tyr-3. (613 aa)
	CYB5A	Cytochrome b5; Belongs to the cytochrome b5 family. (135 aa)
	TYR	Tyrosinase. (585 aa)
	TSNAX	Translin-associated protein X. (378 aa)
	RUNDC1	RUN domain-containing protein 1. (576 aa)
	Rangap1	Ran GTPase-activating protein 1. (592 aa)
	Tsc1-2	Hamartin. (1073 aa)
	T03_4748	Eukaryotic translation initiation factor 4E. (222 aa)
	T03_12281	Ufm1-specific protease 2. (635 aa)
	ACADSB	Short/branched chain specific acyl-CoA dehydrogenase, mitochondrial. (937 aa)
	PDE7A	High affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A; Belongs to the cyclic nucleotide phosphodiesterase family. (394 aa)
	HSP90B1	Endoplasmin. (831 aa)

Your Current Organism:

Trichinella britovi

NCBI taxonomy Id: 45882
Other names: T. britovi

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a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ACADSB	HSP90B1	A0A0V1CS61	A0A0V1CZK4	Short/branched chain specific acyl-CoA dehydrogenase, mitochondrial.	Endoplasmin.	0.491
ACADSB	Rab4b	A0A0V1CS61	A0A0V1CNM3	Short/branched chain specific acyl-CoA dehydrogenase, mitochondrial.	Ras-related protein Rab-4B.	0.525
ACADSB	Trpv4	A0A0V1CS61	A0A0V1CYD3	Short/branched chain specific acyl-CoA dehydrogenase, mitochondrial.	Transient receptor potential cation channel subfamily V member 4; Belongs to the transient receptor (TC 1.A.4) family.	0.512
ACADSB	Tsc1	A0A0V1CS61	A0A0V1DAX3	Short/branched chain specific acyl-CoA dehydrogenase, mitochondrial.	Hamartin.	0.730
ACADSB	Tsc1-2	A0A0V1CS61	A0A0V1DIE2	Short/branched chain specific acyl-CoA dehydrogenase, mitochondrial.	Hamartin.	0.730
ACADSB	cav-1	A0A0V1CS61	A0A0V1D662	Short/branched chain specific acyl-CoA dehydrogenase, mitochondrial.	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.	0.591
ACADSB	cav1	A0A0V1CS61	A0A0V1CWM1	Short/branched chain specific acyl-CoA dehydrogenase, mitochondrial.	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.	0.591
ALG2	Ogt	A0A0V1CEL9	A0A0V1CPF7	Alpha-1,3/1,6-mannosyltransferase ALG2.	UDP-N-acetylglucosamine-peptide N-acetylglucosaminyltransferase.	0.533
ALG2	RAD51C	A0A0V1CEL9	A0A0V1CZG1	Alpha-1,3/1,6-mannosyltransferase ALG2.	DNA repair protein RAD51-like protein 3.	0.402
ALG2-2	Ogt	A0A0V1CPV2	A0A0V1CPF7	Alpha-1,3/1,6-mannosyltransferase ALG2.	UDP-N-acetylglucosamine-peptide N-acetylglucosaminyltransferase.	0.533
ALG2-2	RAD51C	A0A0V1CPV2	A0A0V1CZG1	Alpha-1,3/1,6-mannosyltransferase ALG2.	DNA repair protein RAD51-like protein 3.	0.402
ALG2-3	Ogt	A0A0V1CR30	A0A0V1CPF7	Alpha-1,3/1,6-mannosyltransferase ALG2.	UDP-N-acetylglucosamine-peptide N-acetylglucosaminyltransferase.	0.533
ALG2-3	RAD51C	A0A0V1CR30	A0A0V1CZG1	Alpha-1,3/1,6-mannosyltransferase ALG2.	DNA repair protein RAD51-like protein 3.	0.402
ATP7A	GRASP	A0A0V1D500	A0A0V1CJH2	Copper-transporting ATPase 1.	General receptor for phosphoinositides 1-associated scaffold protein.	0.743
Actbeta	GRASP	A0A0V1D911	A0A0V1CJH2	Inhibin beta chain.	General receptor for phosphoinositides 1-associated scaffold protein.	0.517
Actbeta	T03_17586	A0A0V1D911	A0A0V1CM73	Inhibin beta chain.	Four-domain proteases inhibitor.	0.827
Aggf1	Cherp	A0A0V1D2A4	A0A0V1CEN8	Angiogenic factor with G patch and FHA domains 1.	Calcium homeostasis endoplasmic reticulum protein.	0.445
Aggf1	Eif4h	A0A0V1D2A4	A0A0V1CI11	Angiogenic factor with G patch and FHA domains 1.	Eukaryotic translation initiation factor 4H.	0.773
CANX	DERL1	A0A0V1D6Z0	A0A0V1DA87	Calnexin.	Derlin; May be involved in the degradation of misfolded endoplasmic reticulum (ER) luminal proteins; Belongs to the derlin family.	0.536
CANX	HSP90B1	A0A0V1D6Z0	A0A0V1CZK4	Calnexin.	Endoplasmin.	0.928