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dapA-2 dapA-2 murE murE B4102_1515 B4102_1515 B4102_1622 B4102_1622 B4102_1779 B4102_1779 B4102_1921 B4102_1921 B4102_2392 B4102_2392 B4102_2439 B4102_2439 B4102_2440 B4102_2440 dapB dapB lysA lysA B4102_2684 B4102_2684 dapF dapF B4102_3098 B4102_3098 B4102_3231 B4102_3231 B4102_3520 B4102_3520 argD argD B4102_3902 B4102_3902 B4102_3961 B4102_3961 B4102_4053 B4102_4053 B4102_4207 B4102_4207 murF murF rex rex B4102_0334 B4102_0334 dapH dapH B4102_0557 B4102_0557 B4102_0651 B4102_0651 B4102_0822 B4102_0822 asd asd B4102_1073 B4102_1073 dapA dapA B4102_1081 B4102_1081
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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dapA-2Dihydrodipicolinate synthase; Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA). (309 aa)
murEUDP-N-acetylmuramoylalanyl-D-glutamate--2, 6-diaminopimelate ligase; Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan. Belongs to the MurCDEF family. MurE subfamily. (486 aa)
B4102_1515Hypothetical protein; Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase and related deacylases. (470 aa)
B4102_1622Aspartokinase; Belongs to the aspartokinase family. (410 aa)
B4102_1779Homoserine dehydrogenase. (430 aa)
B4102_1921Homoserine dehydrogenase. (331 aa)
B4102_2392N-acetyl-L,L-diaminopimelate deacetylase. (386 aa)
B4102_2439Hypothetical protein; Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase and related deacylases. (447 aa)
B4102_2440Hypothetical protein; Predicted transcriptional regulator of N-Acetylglucosamine utilization, GntR family. (240 aa)
dapBDihydrodipicolinate reductase; Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate; Belongs to the DapB family. (267 aa)
lysADiaminopimelate decarboxylase; Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine. (439 aa)
B4102_2684Hypothetical protein; Trehalose operon transcriptional repressor. (238 aa)
dapFDiaminopimelate epimerase; Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L- lysine and an essential component of the bacterial peptidoglycan. (328 aa)
B4102_3098Hypothetical protein; Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase and related deacylases. (463 aa)
B4102_3231Hypothetical protein; Predicted transcriptional regulator of N-Acetylglucosamine utilization, GntR family. (236 aa)
B4102_3520Hypothetical protein. (134 aa)
argDAcetylornithine aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily. (399 aa)
B4102_3902Transcriptional regulator, GntR family domain / Aspartate aminotransferase. (473 aa)
B4102_3961Hypothetical protein; Catalyzes the cleavage of p-aminobenzoyl-glutamate to p-aminobenzoate and glutamate, subunit A. (421 aa)
B4102_4053Hypothetical protein. (267 aa)
B4102_4207Aspartokinase; Belongs to the aspartokinase family. (453 aa)
murFUDP-N-acetylmuramoylalanyl-D-glutamyl-2, 6-diaminopimelate--D-alanyl-D-alanine ligase; Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein; Belongs to the MurCDEF family. MurF subfamily. (459 aa)
rexHypothetical protein; Modulates transcription in response to changes in cellular NADH/NAD(+) redox state. (219 aa)
B4102_0334N-acetyl-L,L-diaminopimelate deacetylase; Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate. (372 aa)
dapH2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-acetyltransferase; Catalyzes the transfer of an acetyl group from acetyl-CoA to tetrahydrodipicolinate. (233 aa)
B4102_0557Hypothetical protein; Catalyzes the cleavage of p-aminobenzoyl-glutamate to p-aminobenzoate and glutamate, subunit A. (392 aa)
B4102_0651Hypothetical protein. (87 aa)
B4102_0822Hypothetical protein; Catalyzes the cleavage of p-aminobenzoyl-glutamate to p-aminobenzoate and glutamate, subunit A. (400 aa)
asdAspartate-semialdehyde dehydrogenase; Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl- 4-phosphate; Belongs to the aspartate-semialdehyde dehydrogenase family. (348 aa)
B4102_1073Aspartokinase; Belongs to the aspartokinase family. (412 aa)
dapADihydrodipicolinate synthase; Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA). (289 aa)
B4102_1081Hypothetical protein; Transcriptional regulator in cluster with Zn-dependent hydrolase. (241 aa)
Your Current Organism:
Bacillus sporothermodurans
NCBI taxonomy Id: 46224
Other names: B. sporothermodurans, CIP 104910, DSM 10599, LMG 17668, LMG 17894, LMG:17668, LMG:17894, strain M215, strain MB 581
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